Association of anti-smoking legislation with rates of hospital admission for cardiovascular and respiratory conditions
Open accessAbstract
BACKGROUND: Few studies have examined the impact of anti-smoking legislation on respiratory or cardiovascular conditions other than acute myocardial infarction. We studied rates of hospital admission attributable to three cardiovascular conditions (acute myocardial infarction, angina, and stroke) and three respiratory conditions (asthma, chronic obstructive pulmonary disease, and pneumonia or bronchitis) after the implementation of smoking bans. METHODS: We calculated crude rates of admission to hospital in Toronto, Ontario, from January 1996 (three years before the first phase of a smoking ban was implemented) to March 2006 (two years after the last phase was implemented. We used an autoregressive integrated moving-average (ARIMA) model to test for a relation between smoking bans and admission rates. We compared our results with similar data from two Ontario municipalities that did not have smoking bans and with conditions (acute cholecystitis, bowel obstruction and appendicitis) that are not known to be related to second-hand smoke. RESULTS: Crude rates of admission to hospital because of cardiovascular conditions decreased by 39% (95% CI 38%-40%) and admissions because of respiratory conditions decreased by 33% (95% CI 32%-34%) during the ban period affecting restaurant settings. No consistent reductions in these rates were evident after smoking bans affecting other settings. No significant reductions were observed in control cities or for control conditions. INTERPRETATION: Our results serve to expand the list of health outcomes that may be ameliorated by smoking bans. Further research is needed to establish the types of settings in which smoking bans are most effective. Our results lend legitimacy to efforts to further reduce public exposure to tobacco smoke.
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In Toronto, after a smoking ban in restaurants and related settings, rates of cardiovascular conditions decreased by 39% and admissions for respiratory conditions decreased by 33%, with no changes in control cities or control end points.
“Rates of cardiovascular conditions decreased by 39% and admissions for respiratory conditions decreased by 33%; no changes were observed in control cities or control end points.”
From Population Approaches to Improve Diet, Physical Activity, and Smoking Habits: A Scientific Statement From the American Heart Association (2012) · cites this paper as [417]
Four new reports published since the reviews all demonstrated reductions in cardiovascular and/or respiratory events following smoking bans.
“Since these reviews, 4 new reports of the effects of smoking bans on cardiovascular and respiratory conditions have been published, all demonstrating reductions in cardiovascular and/or respiratory events following smoking bans.”
From Population Approaches to Improve Diet, Physical Activity, and Smoking Habits: A Scientific Statement From the American Heart Association (2012) · cites this paper as [417]
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- Barone-Adesi F, Vizzini L, Merletti F, et al. Short-term effects of Italian smoking regulation on rates of hospital admission for acute myocardial infarction. Eur Heart J 2006;27:2468-72. Correspondence to: Dr. Alisa Naiman, 491 Lawrence Ave. W., Ste. 101, Toronto ON M5M 1C9; a.naiman@utoronto.ca
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BackgroundClean Indoor Air Acts reduce the burden of adverse cardiovascular outcomes
Lippert, W. C., & Gustat, J. (2012) · Public Health · doi:10.1016/j.puhe.2012.01.005 · Cited by 18 · see citing works
Ho, V., Ross, J. S., Steiner, C. A., Mandawat, A., Short, M., Ku-Goto, M.-H., & Krumholz, H. M. (2017) · Medical Care Research and Review · doi:10.1177/1077558716668646 · Cited by 20 · see citing works
Galán, I., Simón, L., Flores, V., Ortíz, C., Fernández-Cuenca, R., Linares, C., Boldo, E., Medrano, M. J., & Pastor‐Barriuso, R. (2015) · BMJ Open · doi:10.1136/bmjopen-2015-008892 · Cited by 16 · see citing works
“7 Regions and countries where preventing SHS exposure is limited to the workplace failed to observe any bene fi ts 14 30 or were very limited.”
BackgroundA review of the evidence on smoking bans and incidence of heart disease
Lee, P. N., Fry, J. S., & Forey, B. A. (2014) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2014.06.014 · Cited by 17 · see citing works
Shiue, I. (2014) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph110303096 · Cited by 17 · see citing works
McDaniel, J. (2018) · Perspectives in Public Health · doi:10.1177/1757913918772598 · Cited by 17 · see citing works
Dusemund, F., Baty, F., & Brutsche, M. H. (2014) · Tobacco Control · doi:10.1136/tobaccocontrol-2013-051290 · Cited by 16 · see citing works
Repace, J., Zhang, B., Bondy, S. J., Benowitz, N. L., & Ferrence, R. G. (2012) · Indoor Air · doi:10.1111/ina.12004 · Cited by 15 · see citing works
Bird, Y., Kashaniamin, L., Nwankwo, C., & Moraros, J. (2020) · Healthcare · doi:10.3390/healthcare8010020 · Cited by 15 · see citing works
Community Interventions for Childhood Asthma ED Visits and Hospitalizations: A Systematic Review
Gill, I. J., Shah, A., Lee, E. K., Sommer, R., Ross, K. R., Bole, A., & Freedman, D. A. (2022) · PEDIATRICS · doi:10.1542/peds.2021-054825 · Cited by 14 · see citing works
Gupta, R., Luo, J., Anderson, R. H., & Ray, A. (2011) · Europe PMC (PubMed Central) · Cited by 15 · see citing works
Johnson, E. L., & Beal, J. R. (2012) · Nicotine & Tobacco Research · doi:10.1093/ntr/nts216 · Cited by 13 · see citing works
Effect of Uruguay’s National 100% Smokefree Law on Emergency Visits for Bronchospasm
Kalkhoran, S. M., Sebrié, E. M., Sandoya, E., & Glantz, S. A. (2015) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2014.12.009 · Cited by 12 · see citing works
Christophi, C. A., Paisi, M., Pampaka, D., Kehagias, M., Vardavas, C. I., & Connolly, G. N. (2013) · BMC Public Health · doi:10.1186/1471-2458-13-76 · Cited by 14 · see citing works
“Over the past few years, an accumulating body of evidence has connected SHS with concerns about the health effects of indoor air-quality in public spaces, especially hospitality venues [6] and a number of studies have indicated that the introduction of smoking bans from all public spaces results in improved air-qualit…”
BackgroundFu, Z., Jiang, H., Xu, Z., Li, H., Wu, N., & Yin, P. (2020) · Annals of Translational Medicine · doi:10.21037/atm.2020.03.145 · Cited by 12 · see citing works
“At a level of society, the legislated bans on smoking seem to be associated with the reduced rates of exacerbation or admission to hospital in COPD population in some developed countries (36-38) and this advance may be mainly ascribed to the decrease of SHS.”
BackgroundCarrión-Valero, F., Izquierdo, J. Q. I., González-Monte, C., Taberner-Alberola, F., Rodrigo, J. A. L., Chorro, F. J., & Martin-Moreno, J. M. (2020) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2019.04.009 · Cited by 12 · see citing works
“The harmful effects of tobacco are not confined to active smokers, but also impact those exposed to secondhand smoke, which is listed as the third leading cause of preventable poor health and premature death in the developed world.(4) Despite compelling evidence of the benefits of laws and policies that prohibit smoki…”
BackgroundGambaryan, M. G., Drapkina, O. M., Васильевна, К. А., Popovich, M. V., & Salagai, O. O. (2022) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2022-3194 · Cited by 13 · see citing works
Smoke-Free Policies and 30-Day Readmission Rates for Chronic Obstructive Pulmonary Disease
Stallings‐Smith, S., Hamadi, H. Y., Peterson, B. N., Apatu, E., & Spaulding, A. (2019) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2019.06.008 · Cited by 11 · see citing works
Peña, M. S. B., Swett, K. R., Kaplan, R. C., Perreira, K. M., Daviglus, M. L., Kansal, M. M., Cai, J., Giachello, A. L. M., Gellman, M. D., Velazquez, E. J., et al. (2018) · Open Heart · doi:10.1136/openhrt-2018-000831 · Cited by 11 · see citing works
Marchese, M. E., Shamo, F., Miller, C. E., Wahl, R. L., & Li, Y. (2015) · Preventing Chronic Disease · doi:10.5888/pcd12.150144 · Cited by 10 · see citing works
Vellakkal, S., Khan, Z., Alavani, H., Fledderjohann, J., & Stückler, D. (2022) · Public Health · doi:10.1016/j.puhe.2022.03.021 · Cited by 9 · see citing works
Habit or addiction: the critical tension in deciding who should enforce hospital smoke-free policies
Lawn, S. (2011) · Canadian Medical Association Journal · doi:10.1503/cmaj.111579 · Cited by 9 · see citing works
Economic Effect of Smoke-Free Ordinances on 11 Missouri Cities
Kayani, N., Cowan, S., Homan, S., Wilson, J., Warren, V., & Yun, S. (2012) · Preventing Chronic Disease · doi:10.5888/pcd9.110277 · Cited by 9 · see citing works
Yıldız, F., Baris, S. A., Başyiğit, İ., Boyacı, H., Aydinlik, H., & Sonmez, P. (2014) · Eastern Mediterranean Health Journal · doi:10.26719/2014.20.12.774 · Cited by 9 · see citing works
“5% overall reduction in hospital admissions for respiratory conditions (17).”
BackgroundChen, C., Huang, Y., & Yang, C. (2018) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2018.1547669 · Cited by 8 · see citing works
“Ideally, a study assessing the effects of SHS needs to be restricted to a non-smoking population (Naiman, Glazier, and Moineddin 2010).”
BackgroundReassessing the evidence relating smoking bans to heart disease
Lee, P. N., & Fry, J. S. (2011) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2011.09.002 · Cited by 8 · see citing works
Yang, Y.-N., Huang, Y., & Yang, C. (2017) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2017.1367085 · Cited by 7 · see citing works
“The importance of restaurants in exposure to smoking may lie in their ubiquity and frequency at which individuals dine out (Naiman et al. 2010) and on health of restaurant workers (Madureira et al. 2012; Pacheco et al. 2012, 2013).”
BackgroundInfluentialAzagba, S., & Asbridge, M. (2013) · Addictive Behaviors · doi:10.1016/j.addbeh.2013.08.006 · Cited by 7 · see citing works
Analyses of the Impact of the Ohio Smoke-Free Workplace Act
Klein, E. G., & Hood, N. (2011) · Cited by 7 · see citing works
Updating the evidence relating smoking bans to incidence of heart disease
Lee, P. N., Fry, J. S., & Thornton, A. J. (2018) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2018.11.014 · Cited by 7 · see citing works
Smoking asthmatics, a neglected large phenotype of asthmatic patients
Katsaounou, P. A., Ioannou, M., Hyland, M. E., Odemyr, M., Otto, S., Anne, L., Matthias, G., Garcia, C. L., Xavier, J., & Ismail, K. (2019) · Open Journal of Asthma · doi:10.17352/oja.000010 · Cited by 7 · see citing works
“Furthermore, from observational studies it seems that smoke free laws reduce admission rates for asthma in adults and children [49,50].”
BackgroundВасильевна, К. А., Agishina, T. A., Gambaryan, M. G., Duplyakov, D. V., & Drapkina, O. M. (2020) · Экология человека · doi:10.33396/1728-0869-2020-5-37-44 · Cited by 6 · see citing works
Gambaryan, M. G., Васильевна, К. А., & Drapkina, O. M. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20105893 · Cited by 6 · see citing works
“A. Nyman et al. observed a 33% decrease in hospital admissions for respiratory diseases during a restaurant ban in Toronto [17].”
BackgroundResultMorito, N., Miura, S.-I., Yano, M., Hitaka, Y., Nishikawa, H., & Saku, K. (2015) · Cardiology Research · doi:10.14740/cr404e · Cited by 6 · see citing works
Salagay, O. О., Antonov, N. S., Sakharova, G. M., Peredelskaya, M. Y., Demidov, I., & Стародубов, В. И. (2019) · Russian Journal of Preventive Medicine · doi:10.17116/profmed2019220627 · Cited by 6 · see citing works
Ye, S., Wang, R., & Zhang, B. (2022) · Health Services and Outcomes Research Methodology · doi:10.1007/s10742-021-00267-3 · Cited by 5 · see citing works
“2011), several studies were conducted to evaluate the reductions in cardiovascular, cerebrovascular, and respiratory related outcomes (mortality, hospital admission, self-reported symptoms) following the implementation of the Irish smoking ban (Stallings-Smith et al. 2013; Goodman et al. 2007; Cronin et al. 2012; Naim…”
BackgroundAre you a regular passive smoker?
Mearns, B. M. (2010) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2010.105 · Cited by 5 · see citing works
Impact of smoke-free legislation on stroke risk: A systematic review and meta-analysis
Chua, Z. X., Amanda, C. Y. L., Lam, T. J. R., Ong, J. S. P., Lim, Y. W. S., Kumar, S., Lim, M. J. R., Tan, B. Y., Aik, J., & Ho, A. F. W. (2024) · European Stroke Journal · doi:10.1177/23969873241293566 · Cited by 5 · see citing works
“In two studies, 17,42 RR and CI was determined using a Poisson regression model accounting for temporal trends.”
Mackay, D., Irfan, M. M., Haw, S. J., & Pell, J. P. (2011) · Postgraduate Medical Journal · doi:10.1136/pgmj.2010.199026rep · Cited by 4 · see citing works
- Authors
- Naiman, A., Glazier, R. H., & Moineddin, R.
- Affiliations
- University of Toronto (CA)
- St. Michael's Hospital (CA)
- Venue
- Canadian Medical Association Journal
- Publisher
- CMA Joule Inc.
- Published
- 2010-04-12
- Volume
- 182
- Issue
- 8
- Pages
- 761-767
- ISSN
- 0820-3946 (ISSN-L)
- 1488-2329
- PMC
- PMC2871198
- OpenAlex
- W2103760950
- Cited by
- 129
- References
- 22
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 6 · 2022: 5 · 2021: 3 · 2020: 7 · 2019: 4 · 2018: 8 · 2017: 10 · 2016: 6 · 2015: 10 · 2014: 9 · 2013: 15 · 2012: 19
- FWCI
- 12.78
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Canadian Medical Association Journal (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Institute for Clinical Evaluative Sciences
- Ontario Ministry of Health and Long-Term Care
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- smoking bans, anti-smoking legislation, passive smoking, hospitalization, cardiovascular disease, respiratory diseases, acute myocardial infarction, angina pectoris, stroke, asthma, chronic obstructive pulmonary disease, pneumonia, bronchitis, public health policy
- MeSH terms
- Adult, Cardiovascular Diseases, Female, Humans, Lung Diseases, Male, Ontario, Patient Admission, Smoking, Social Control, Formal, Tobacco Smoke Pollution
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