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Cited by 839

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Biochemical markers of muscular damage

Brancaccio, Paola, Lippi, Giuseppe, Maffulli, Nicola·2010·cclm

Abstract

Muscle tissue may be damaged following intense prolonged training as a consequence of both metabolic and mechanical factors. Serum levels of skeletal muscle enzymes or proteins are markers of the functional status of muscle tissue, and vary widely in both pathological and physiological conditions. Creatine kinase, lactate dehydrogenase, aldolase, myoglobin, troponin, aspartate aminotransferase, and carbonic anhydrase CAIII are the most useful serum markers of muscle injury, but apoptosis in muscle tissues subsequent to strenuous exercise may be also triggered by increased oxidative stress. Therefore, total antioxidant status can be used to evaluate the level of stress in muscle by other markers, such as thiobarbituric acid-reactive substances, malondialdehyde, sulfhydril groups, reduced glutathione, oxidized glutathione, superoxide dismutase, catalase and others. As the various markers provide a composite picture of muscle status, we recommend using more than one to provide a better estimation of muscle stress. Clin Chem Lab Med 2010;48:757–67.

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Metadata

Authors
Brancaccio, P., Lippi, G., & Maffulli, N.
Venue
cclm
Published
2010-06-01
Volume
48
Issue
6
Pages
757-767
ISSN
  • 1434-6621 (ISSN-L)
  • 1437-4331
OpenAlex
W2088894776
Cited by
839
References
2
FWCI
29.70
Type
journal article
Language
en
Open access
closed

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