Α Review on the Acute Phase Response in Major Depression

Stress and immunity: An integrated view of relationships between the brain and the immune system

Dantzer, R., & Kelley, K. W. (1989) · Life Sciences · doi:10.1016/0024-3205(89)90345-7 · Cited by 534 · see citing works

Evidence for a systemic immune activation during depression: results of leukocyte enumeration by flow cytometry in conjunction with monoclonal antibody staining

Maes, M., Lambrechts, J., Bosmans, E., Jacobs, J., Suy, E., Vandervorst, C., De Jonckheere, C., Minner, B., & Raus, J. (1992) · Psychological Medicine · doi:10.1017/s0033291700032712 · Cited by 275 · see citing works

Depression‐related disturbances in mitogen‐induced lymphocyte responses and interleukin‐1β and soluble interleukin‐2 receptor production

Maes, M., Bosmans, E., Suy, E., Vandervorst, C., DeJonckheere, C., & Raus, J. (1991) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1991.tb03163.x · Cited by 268 · see citing works

From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.

Slavich, G. M., & Irwin, M. R. (2014) · Psychological Bulletin · doi:10.1037/a0035302 · Cited by 2,206 · see citing works

Twenty years of research on cytokine-induced sickness behavior

Dantzer, R., & Kelley, K. W. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2006.09.006 · Cited by 1,420 · see citing works

Effects of stress on immune function: The good, the bad, and the beautiful

Dhabhar, F. S. (2014) · Immunologic Research · doi:10.1007/s12026-014-8517-0 · Cited by 1,343 · see citing works

Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors

Berk, M., Kapczinski, F., Andreazza, A. C., Dean, O. M., Giorlando, F., Maes, M., Yücel, M., Gama, C. S., Dodd, S., Dean, B., et al. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.10.001 · Cited by 1,178 · see citing works

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness

Maes, M., Galecki, P., Chang, Y. S., & Berk, M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.05.004 · Cited by 1,140 · see citing works

Cytokines for psychologists: Implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition.

Maier, S. F., & Watkins, L. R. (1998) · Psychological Review · doi:10.1037/0033-295x.105.1.83 · Cited by 1,130 · see citing works

Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection and Immunopathology

Dhabhar, F. S. (2009) · Neuroimmunomodulation · doi:10.1159/000216188 · Cited by 903 · see citing works

Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile

Penninx, B. W., Milaneschi, Y., Lamers, F., & Vogelzangs, N. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-129 · Cited by 839 · see citing works

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression

Leonard, B., & Maes, M. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.12.005 · Cited by 805 · see citing works

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

Maes, M., Leonard, B. E., Myint, A. M., Kubera, M., & Verkerk, R. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.12.017 · Cited by 700 · see citing works

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

Maes, M., Berk, M., Goehler, L., Song, C., Anderson, G., Gałecki, P., & Leonard, B. (2012) · BMC Medicine · doi:10.1186/1741-7015-10-66 · Cited by 629 · see citing works

Major Depression and Activation of The Inflammatory Response System

Maes, M. (1999) · Advances in Experimental Medicine and Biology · doi:10.1007/978-0-585-37970-8_2 · Cited by 617 · see citing works

Cytokine Alterations in Bipolar Disorder: A Meta-Analysis of 30 Studies

Modabbernia, A., Taslimi, S., Brietzke, E., & Ashrafi, M. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.01.007 · Cited by 596 · see citing works

Depression and C-Reactive Protein in US Adults: Data From the Third National Health and Nutrition Examination Survey

Ford, D. E., & Erlinger, T. P. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.9.1010 · Cited by 544 · see citing works

Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression

Maes, M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.06.014 · Cited by 544 · see citing works

Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut

Maes, M., Kubera, M., Leunis, J.-C., & Berk, M. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.02.023 · Cited by 446 · see citing works

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

Kubera, M., Obuchowicz, E., Goehler, L., Brzeszcz, J., & Maes, M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.08.026 · Cited by 443 · see citing works

Cerebrospinal Cytokine Levels in Patients with Acute Depression

Levine, J., Barak, Y., Chengappa, K. N. R., Rapoport, A., Rebey, M., & Barak, V. (1999) · Neuropsychobiology · doi:10.1159/000026615 · Cited by 354 · see citing works

The Compensatory Immune-Regulatory Reflex System (CIRS) in Depression and Bipolar Disorder

Maes, M., & Carvalho, A. F. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1016-x · Cited by 306 · see citing works

Association of Interleukin‐6 and Other Biologic Variables with Depression in Older People Living in the Community

Dentino, A. N., Pieper, C. F., Rao, K. M. K., Currie, M. S., Harris, T., Blazer, D. G., & Cohen, H. J. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb01894.x · Cited by 287 · see citing works

The Proinflammatory Cytokine, Interleukin-1α, Reduces Glucocorticoid Receptor Translocation and Function¹

Pariante, C. M., Pearce, B. D., Pisell, T. L., Sanchez, C. I., Po, C., Su, C., & Miller, A. H. (1999) · Endocrinology · doi:10.1210/en.140.9.4359 · Cited by 40 · see citing works

Effects of Cytokines on Glucocorticoid Receptor Expression And Function: Glucocorticoid Resistance and Relevance to Depression

Miller, A. H., Pariante, C. M., & Pearce, B. D. (1999) · Advances in Experimental Medicine and Biology · doi:10.1007/978-0-585-37970-8_7 · Cited by 203 · see citing works

Peripheral Markers of Depression

Nobis, A., Zalewski, D., & Waszkiewicz, N. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9123793 · Cited by 197 · see citing works

A critical review of the mechanism of action for the selective serotonin reuptake inhibitors: Do these drugs possess anti-inflammatory properties and how relevant is this in the treatment of depression?

Walker, F. R. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.10.002 · Cited by 175 · see citing works

Multiple aberrations in shared inflammatory and oxidative & nitrosative stress (IO&NS) pathways explain the co-association of depression and cardiovascular disorder (CVD), and the increased risk for CVD and due mortality in depressed patients

Maes, M., Ruckoanich, P., Chang, Y. S., Mahanonda, N., & Berk, M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.06.008 · Cited by 169 · see citing works

Comorbidity between depression and asthma via immune-inflammatory pathways: a meta-analysis

Jiang, M., Qin, P., & Yang, X. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.04.027 · Cited by 146 · see citing works

Targeting classical IL-6 signalling or IL-6<i>trans</i>-signalling in depression?

Maes, M., Anderson, G., Kubera, M., & Berk, M. (2014) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2014.888417 · Cited by 140 · see citing works

Major Differences in Neurooxidative and Neuronitrosative Stress Pathways Between Major Depressive Disorder and Types I and II Bipolar Disorder

Maes, M., Landucci Bonifacio, K., Morelli, N. R., Vargas, H. O., Barbosa, D. S., Carvalho, A. F., & Nunes, S. O. V. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1051-7 · Cited by 102 · see citing works

T helper 17 cells may drive neuroprogression in major depressive disorder: Proposal of an integrative model

Slyepchenko, A., Maes, M., Köhler, C. A., Anderson, G., Quevedo, J., Alves, G. S., Berk, M., Fernandes, B. S., & Carvalho, A. F. (2016) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.02.002 · Cited by 89 · see citing works

Indicators of immune activation in depressed patients

Sluzewska, A. (1999) · Advances in Experimental Medicine and Biology · doi:10.1007/978-0-585-37970-8_4 · Cited by 66 · see citing works

A Study of TNF-α, TGF-β, IL-10, IL-6, and IFN-γ Gene Polymorphisms in Patients with Depression

Mihailova, S., Ivanova-Genova, E., Lukanov, T., Stoyanova, V., Milanova, V., & Naumova, E. (2016) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2016.03.005 · Cited by 61 · see citing works

Does ceasing exercise induce depressive symptoms? A systematic review of experimental trials including immunological and neurogenic markers

Morgan, J. A., Olagunju, A. T., Corrigan, F., & Baune, B. T. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.02.058 · Cited by 34 · see citing works

Leukocytosis and hypoalbuminemia in mixed bipolar states: Evidence for immune activation

Cassidy, F., Wilson, W. H., & Carroll, B. J. (2002) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2002.0_435.x · Cited by 30 · see citing works