Santalum Genus: phytochemical constituents, biological activities and health promoting-effects
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Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (α-santalol and β-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.
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The worldwide increasing tendency toward using phytochemicals may be due to low toxicity and synergistic effects.
“The worldwide increasing tendency toward using phytochemicals may be due to low toxicity, and synergistic effects [199,200,201].”
From Multi-Target Mechanisms of Phytochemicals in Alzheimer’s Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation (2022) · cites this paper as [201]
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In my experience, matron had no time for kindness
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Cited by
Sorted by citations
Sharifi-Rad, J., Rapposelli, S., Sestito, S., Herrera-Bravo, J., Arancibia-Diaz, A., Salazar, L. A., Yeskaliyeva, B., Beyatli, A., Leyva-Gómez, G., González-Contreras, C., et al. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12091515 · Cited by 125 · see citing works
Self-citation
- Authors
- Sharifi-Rad, J., Quispe, C., Turgumbayeva, A., Mertdinç, Z., Tütüncü, S., Aydar, E. F., Özçelik, B., Anna, S.-W., Mariola, S., Koziróg, A., Otlewska, A., Antolak, H., Sen, S., Acharya, K., Lapava, N., Emamzadeh-Yazdi, S., Martorell, M., Kumar, M., Varoni, E. M., Iriti, M., & Calina, D.
- Affiliations
- Facultad de Medicina , Universidad del Azuay , Cuenca , Ecuador
- Arturo Prat University (CL)
- Al-Farabi Kazakh National University (KZ)
- Istanbul Technical University (TR)
- Department of Forage Crop Production , Institute of Soil Science and Plant Cultivation – State Research Institute , Czartoryskich 8, 24-100 Puławy , Poland
- Lodz University of Technology (PL)
- University of Calcutta (IN)
- Fakir Chand College (IN)
- Vitebsk State Medical University (BY)
- Department of Plant and Soil Sciences , University of Pretoria , Gauteng 0002 , Pretoria , South Africa
- University of Concepción (CL)
- ICAR - Central Institute for Research on Cotton Technology (IN)
- University of Milan (IT)
- Department of Clinical Pharmacy , University of Medicine and Pharmacy of Craiova , 200349 Craiova , Romania
- Corresponding author
- Iriti, Marcello
- ORCID
- Venue
- Zeitschrift für Naturforschung C
- Publisher
- Walter de Gruyter GmbH
- Published
- 2022-09-07
- Volume
- 78
- Issue
- 1-2
- Pages
- 9-25
- ISSN
- 0341-0471 (ISSN-L)
- 0939-5075
- 1865-7125
- OpenAlex
- W4294919857
- Cited by
- 39
- References
- 103
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 12 · 2023: 10 · 2022: 6
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Zeitschrift für Naturforschung C (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (submittedVersion, cc-by)
- UpSpace Institutional Repository (University of Pretoria) (submittedVersion, cc-by)
- Istanbul Technical University Academic Open Archive (Istanbul Technical University) (submittedVersion)
- Greater South Information System
- Funders
- Agencia Nacional de Investigación y Desarrollo (ACE210012)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Wood and Agarwood Research
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- Santalum, sandalwood, Santalaceae, phytochemical constituents, essential oils, α-santalol, β-santalol, phenolic compounds, fatty acids, antioxidant activity, anti-inflammatory activity, antibacterial activity, antifungal activity, antiviral activity, neuroleptic activity, antidiabetic activity, hypolipidemic activity, anticancer activity, safety, traditional medicine, health promotion
- MeSH terms
- Polycyclic Sesquiterpenes, Humans, Oils, Volatile, Plant Extracts, Plant Oils, Sesquiterpenes, Santalum, Phytochemicals
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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