Cited by 227Obsessive-Compulsive Spectrum DisordersDeep Brain Stimulation and Movement DisordersStuttering Research and Treatment

The DOI matches its Crossref record; 139 of the 139 references it cites were found in a registry or an index.

Neurobiology of Tourette Syndrome: Current Status and Need for Further Investigation: Table 1.

Open access

Felling, Ryan J., Singer, Harvey S.·2011·The Journal of Neuroscience

DOI 10.1523/jneurosci.0150-11.2011PMC PMC6703258

Open this paper in CoChat — free account Open PDF

Abstract

Tourette syndrome (TS) is a common, chronic neuropsychiatric disorder characterized by the presence of fluctuating motor and phonic tics. The typical age of onset is ∼5-7 years, and the majority of children improve by their late teens or early adulthood. Affected individuals are at increased risk for the development of various comorbid conditions, such as obsessive-compulsive disorder, attention deficit hyperactivity disorder, school problems, depression, and anxiety. There is no cure for tics, and symptomatic therapy includes behavioral and pharmacological approaches. Evidence supports TS being an inherited disorder; however, the precise genetic abnormality remains unknown. Pathologic involvement of cortico-striatal-thalamo-cortical (CSTC) pathways is supported by neurophysiological, brain imaging, and postmortem studies, but results are often confounded by small numbers, age differences, severity of symptoms, comorbidity, use of pharmacotherapy, and other factors. The primary site of abnormality remains controversial. Although numerous neurotransmitters participate in the transmission of messages through CSTC circuits, a dopaminergic dysfunction is considered a leading candidate. Several animal models have been used to study behaviors similar to tics as well as to pursue potential pathophysiological deficits. TS is a complex disorder with features overlapping a variety of scientific fields. Despite description of this syndrome in the late 19th century, there remain numerous unanswered neurobiological questions.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1523/jneurosci.0150-11.2011

Cites

139 of 139 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The functional anatomy of basal ganglia disorders
Albin, R. L., Young, A. B., & Penney, J. B. (1989) · Trends in Neurosciences · doi:10.1016/0166-2236(89)90074-x · Cited by 5,353
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases
Swedo, S. E., Leonard, H. L., Garvey, M., Mittleman, B., Allen, A. J., Perlmutter, S., Dow, S., Zamkoff, J., Dubbert, B. K., & Lougee, L. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.2.264 · Cited by 1,534
The basal ganglia
Graybiel, A. M. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00593-5 · Cited by 1,051
Tourette's syndrome
Leckman, J. F. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11526-1 · Cited by 696
Course of Tic Severity in Tourette Syndrome: The First Two Decades
Leckman, J. F., Zhang, H., Vitale, A., Lahnin, F., Lynch, K., Bondi, C., Kim, Y.-S., & Peterson, B. S. (1998) · Pediatrics · doi:10.1542/peds.102.1.14 · Cited by 685
Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome
Kalanithi, P. S. A., Zheng, W., Kataoka, Y., DiFiglia, M., Grantz, H., Saper, C. B., Schwartz, M. L., Leckman, J. F., & Vaccarino, F. M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0502624102 · Cited by 558
The Basal Ganglia and Involuntary Movements
Mink, J. W. (2003) · Archives of Neurology · doi:10.1001/archneur.60.10.1365 · Cited by 552
Basal Ganglia Volumes in Patients With Gilles de la Tourette Syndrome
Peterson, B. S., Thomas, P., Kane, M. J., Scahill, L., Zhang, H., Bronen, R., King, R. A., Leckman, J. F., & Staib, L. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.4.415 · Cited by 527
Hyperactivity and impaired response habituation in hyperdopaminergic mice
Zhuang, X., Oosting, R. S., Jones, S. R., Gainetdinov, R. R., Miller, G. W., Caron, M. G., & Hen, R. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.1982 · Cited by 500
A Functional Magnetic Resonance Imaging Study of Tic Suppression in Tourette Syndrome
Peterson, B. S., Skudlarski, P., Anderson, A. W., Zhang, H., Gatenby, J. C., Lacadie, C. M., Leckman, J. F., & Gore, J. C. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.4.326 · Cited by 483

Show all 138 references

Research works printed but not linked: 2

10.1176/appi.ajp.164.6.955 · DOI · Paper page
10.1097/00019052-200306000-00017 · DOI

Sorted by citations

Neurobiology of rodent self-grooming and its value for translational neuroscience
Kalueff, A. V., Stewart, A. M., Song, C., Berridge, K. C., Graybiel, A. M., & Fentress, J. C. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2015.8 · Cited by 852
Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders
Dale, R. C., Merheb, V., Pillai, S. C., Wang, D., Cantrill, L. C., Murphy, T. K., Ben‐Pazi, H., Varadkar, S., Aumann, T. D., Horne, M. K., et al. (2012) · Brain · doi:10.1093/brain/aws256 · Cited by 392
Altered structural connectivity of cortico-striato-pallido-thalamic networks in Gilles de la Tourette syndrome
Worbe, Y., Marrakchi‐Kacem, L., Lecomte, S., Valabrègue, R., Poupon, F., Guevara, P., Tucholka, A., Mangin, J., Vidailhet, M., Lehéricy, S., et al. (2014) · Brain · doi:10.1093/brain/awu311 · Cited by 257
Neuromodulation in Tourette syndrome: dopamine and beyond
Buse, J., Schoenefeld, K., Münchau, A., & Roessner, V. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.10.004 · Cited by 185
Imaging the where and when of tic generation and resting state networks in adult Tourette patients
Neuner, I., Werner, C. J., Arrubla, J., StÃ¶cker, T., Ehlen, C., Wegener, H. P., Schneider, F. W., & Shah, N. J. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00362 · Cited by 198
Response Inhibition and Interference Control in Obsessiveâ€“Compulsive Spectrum Disorders
van Velzen, L. S., Vriend, C., de Wit, S. J., & van den Heuvel, O. A. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00419 · Cited by 169
G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders
Wong, T., Li, G., Li, S., Gao, W., Chen, G., Gan, S., Zhang, M., Li, H., Wu, S., & Du, Y. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01427-2 · Cited by 179
The psychopathological spectrum of Gilles de la Tourette syndrome
Cavanna, A. E., & Rickards, H. E. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.10.011 · Cited by 136
Habituation is altered in neuropsychiatric disorders—A comprehensive review with recommendations for experimental design and analysis
McDiarmid, T. A., Bernardos, A. C., & Rankin, C. H. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.05.028 · Cited by 119
Tics and Tourette Syndrome
Singer, H. S. (2019) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000752 · Cited by 126
Self-citation
Neurobiology of rodent self-grooming and its value for translational neuroscience
Kalueff, A. V., Stewart, A., Song, C., Berridge, K. C., Fentress, J. C., & Graybiel, A. M. (2017) · DSpace@MIT (Massachusetts Institute of Technology) · Cited by 114
Support of the histaminergic hypothesis in Tourette Syndrome: association of the histamine decarboxylase gene in a large sample of families
Karagiannidis, I., Dehning, S., Sandor, P., Tárnok, Z., Rizzo, R., Wolańczyk, T., Madruga-Garrido, M., Hebebrand, J., Nöthen, M. M., Lehmkuhl, G., et al. (2013) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2013-101637 · Cited by 111
Dysfunctions of the basal ganglia-cerebellar-thalamo-cortical system produce motor tics in Tourette syndrome
Caligiore, D., Mannella, F., Arbib, M. A., & Baldassarre, G. (2017) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1005395 · Cited by 115
Tourette's syndrome
Cavanna, A. E., & Seri, S. (2013) · BMJ · doi:10.1136/bmj.f4964 · Cited by 109
Meta-Analysis: Risk of Tics Associated With Psychostimulant Use in Randomized, Placebo-Controlled Trials
Cohen, S. C., Mulqueen, J. M., Ferracioli-Oda, E., Stuckelman, Z. D., Coughlin, C. G., Leckman, J. F., & Bloch, M. H. (2015) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2015.06.011 · Cited by 105
Deep brain stimulation for psychiatric disorders: where we are now
Cleary, D. R., Ozpinar, A., Raslan, A. M. T., & Ko, A. L. (2015) · Neurosurgical FOCUS · doi:10.3171/2015.3.focus1546 · Cited by 103
Image-based analysis and long-term clinical outcomes of deep brain stimulation for Tourette syndrome: a multisite study
Johnson, K. A., Fletcher, P. T., Servello, D., Bona, A. R., Porta, M., Ostrem, J. L., Bardinet, É., Welter, M., Lozano, A. M., Baldermann, J. C., et al. (2019) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2019-320379 · Cited by 100
Pathological glutamatergic neurotransmission in Gilles de la Tourette syndrome
Kanaan, A. S., Gerasch, S., García‐García, I., Lampe, L., Pampel, A., Anwander, A., Near, J., Möller, H. E., & Müller‐Vahl, K. (2016) · Brain · doi:10.1093/brain/aww285 · Cited by 96
Behavior Therapy for Tic Disorders: an Evidenced-Based Review and New Directions for Treatment Research
Mcguire, J. F., Ricketts, E. J., Piacentini, J. C., Murphy, T. K., Storch, E. A., & Lewin, A. B. (2015) · Current Developmental Disorders Reports · doi:10.1007/s40474-015-0063-5 · Cited by 86
Towards a primate model of Gilles de la Tourette syndrome: Anatomo-behavioural correlation of disorders induced by striatal dysfunction
Worbe, Y., Sgambato, V., Epinat‐Duclos, J., Chaigneau, M., Tandé, D., François, C., Féger, J., & Tremblay, L. (2012) · Cortex · doi:10.1016/j.cortex.2012.08.020 · Cited by 92
Motor control, habits, complex motor stereotypies, and Tourette syndrome
Singer, H. S. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12281 · Cited by 85
Self-citation
History of Psychosurgery: A Psychiatrist's Perspective
Lapidus, K. A. B., Kopell, B. H., Ben‐Haim, S., Rezai, A. R., & Goodman, W. K. (2013) · World Neurosurgery · doi:10.1016/j.wneu.2013.02.053 · Cited by 87
An Introduction to the Clinical Phenomenology of Tourette Syndrome
Martino, D., Madhusudan, N., Zis, P., & Cavanna, A. E. (2013) · International review of neurobiology · doi:10.1016/b978-0-12-411546-0.00001-9 · Cited by 85
Understanding autism and other neurodevelopmental disorders through experimental translational neurobehavioral models
Homberg, J. R., Kyzar, E. J., Nguyen, M., Norton, W., Pittman, J. T., Poudel, M. K., Gaikwad, S., Nakamura, S., Koshiba, M., Yamanouchi, H., et al. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.03.013 · Cited by 86
The Roles of Phasic and Tonic Dopamine in Tic Learning and Expression
Maia, T. V., & Conceição, V. A. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.05.025 · Cited by 78
Tourette syndrome: a disorder of the social decision-making network
Albin, R. L. (2017) · Brain · doi:10.1093/brain/awx204 · Cited by 80
Cognitive Behavior Therapy for Obsessive-Compulsive and Related Disorders
Lewin, A. B., Wu, M. S., Mcguire, J. F., & Storch, E. A. (2014) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2014.05.002 · Cited by 73
Putting the Pieces Together in Gilles de la Tourette Syndrome: Exploring the Link Between Clinical Observations and the Biological Basis of Dysfunction
Hashemiyoon, R., Kuhn, J., & Visser-Vandewalle, V. E. R. M. (2016) · Brain Topography · doi:10.1007/s10548-016-0525-z · Cited by 75
Alterations in basal ganglia-cerebello-thalamo-cortical connectivity and whole brain functional network topology in Tourette's syndrome
Ramkiran, S., Heidemeyer, L., Gaebler, A. J., Shah, N. J., & Neuner, I. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.101998 · Cited by 69
A proprietary herbal medicine (5‐ L ing G ranule) for T ourette syndrome: a randomized controlled trial
Zheng, Y., Zhang, Z., Han, X., Ding, Y., Chen, Y., Wang, X., Wei, X., Wang, M., Cheng, Y., Nie, Z., et al. (2015) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12432 · Cited by 67
GABA and glutamate in children with Tourette syndrome: A 1 H MR spectroscopy study at 7 T
Mahone, E. M., Puts, N. A. J., Edden, R. A. E., Ryan, M., & Singer, H. S. (2018) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2017.12.005 · Cited by 65
Self-citation
Neuromodulation for obsessive-compulsive disorder
Lapidus, K. A. B., Stern, E. R., Berlin, H. A., & Goodman, W. K. (2014) · Neurotherapeutics · doi:10.1007/s13311-014-0287-9 · Cited by 63
The What, the When, and the Whether of Intentional Action in the Brain: A Meta-Analytical Review
Zapparoli, L., Seghezzi, S., & Paulesu, E. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00238 · Cited by 69
The Role of Atypical Antipsychotics for Treatment of Tourette’s Syndrome: An Overview
Budman, C. L. (2014) · Drugs · doi:10.1007/s40265-014-0254-0 · Cited by 63
Novel pimozide-β-cyclodextrin-polyvinylpyrrolidone inclusion complexes for Tourette syndrome treatment
Bera, H., Chekuri, S., Sarkar, S., Kumar, S., Muvva, N. B., Mothe, S., & Nadimpalli, J. (2015) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2015.12.054 · Cited by 60
The anarchic brain in action
Zapparoli, L., Porta, M., & Paulesu, E. (2015) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000261 · Cited by 57
Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder
Moya, P. R., Wendland, J. R., Rubenstein, L. M., Timpano, K. R., Heiman, G. A., Tischfield, J. A., King, R. A., Andrews, A. M., Ramamoorthy, S., McMahon, F. J., et al. (2013) · Movement Disorders · doi:10.1002/mds.25460 · Cited by 58
Influence of Gender on Tourette Syndrome Beyond Adolescence
Lichter, D. G., & Finnegan, S. G. (2014) · European Psychiatry · doi:10.1016/j.eurpsy.2014.07.003 · Cited by 59
Animal models of tic disorders: A translational perspective
Godar, S. C., Mosher, L. J., Giovanni, G. D., & Bortolato, M. (2014) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2014.09.008 · Cited by 55
Sleep, anxiety and psychiatric symptoms in children with Tourette syndrome and tic disorders
Modafferi, S., Stornelli, M., Chiarotti, F., Cardona, F., & Bruni, O. (2016) · European Journal of Paediatric Neurology · doi:10.1016/j.ejpn.2016.05.003 · Cited by 53
Disrupted topological organization of structural networks revealed by probabilistic diffusion tractography in Tourette syndrome children
Wen, H., Liu, Y., Rekik, I., Wang, S., Zhang, J., Zhang, Y., Peng, Y., & He, H. (2017) · Human Brain Mapping · doi:10.1002/hbm.23643 · Cited by 55
Combining Disrupted and Discriminative Topological Properties of Functional Connectivity Networks as Neuroimaging Biomarkers for Accurate Diagnosis of Early Tourette Syndrome Children
Wen, H., Liu, Y., Rekik, I., Wang, S., Chen, Z., Zhang, J., Zhang, Y., Peng, Y., & He, H. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0519-1 · Cited by 55
Multi-modal multiple kernel learning for accurate identification of Tourette syndrome children
Wen, H., Liu, Y., Rekik, I., Wang, S., Chen, Z., Zhang, J., Zhang, Y., Peng, Y., & He, H. (2016) · Pattern Recognition · doi:10.1016/j.patcog.2016.09.039 · Cited by 52
Clinical development of valbenazine for tics associated with Tourette syndrome
Farber, R., Angelov, A. S., Kim, K. N., Carmack, T., Thai-Cuarto, D., & Roberts, E. (2021) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2021.1898948 · Cited by 49
Mechanisms Underlying Behavior Therapy for Tourette’s Disorder
Essoe, J. K.-Y., Ramsey, K. A., Singer, H. S., Grados, M. A., & Mcguire, J. F. (2021) · Current Developmental Disorders Reports · doi:10.1007/s40474-021-00225-1 · Cited by 48
Self-citation
Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypes
Moya, P. R., Dodman, N. H., Timpano, K. R., Rubenstein, L. M., Rana, Z. H., Fried, R. L., Reichardt, L. F., Heiman, G. A., Tischfield, J. A., King, R. A., et al. (2013) · European Journal of Human Genetics · doi:10.1038/ejhg.2012.245 · Cited by 49
Depicting the composition of gut microbiota in children with tic disorders: an exploratory study
Xi, W., Gao, X., Zhao, H., Luo, X., Li, J., Tan, X., Wang, L., Zhao, J., Wang, J., Yang, G., et al. (2021) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13409 · Cited by 52
Tourette Syndrome as an Independent Risk Factor for Subsequent Sleep Disorders in Children: A Nationwide Population-Based Case–Control Study
Lee, W., Huang, H.-L., Wong, L., Weng, W., Vasylenko, T., Jong, Y., Lin, W., & Ho, S. (2017) · SLEEP · doi:10.1093/sleep/zsw072 · Cited by 45
Functional Neuroanatomy of Tics
Neuner, I., Schneider, F. W., & Shah, N. J. (2013) · International review of neurobiology · doi:10.1016/b978-0-12-411546-0.00002-0 · Cited by 44
Efficacy of Glutamate Modulators in Tic Suppression: A Double-Blind, Randomized Control Trial of D-serine and Riluzole in Tourette Syndrome
Lemmon, M. E., Grados, M. A., Kline, T., Thompson, C. B., Ali, S. F., & Singer, H. S. (2015) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2015.02.002 · Cited by 41
Self-citation
Heritability of tic disorders: a twin-family study
Zilhäo, N. R., Olthof, M. C., Smit, D. J. A., Cath, D. C., Ligthart, L., Mathews, C. A., Delucchi, K., Boomsma, D. I., & Dolan, C. V. (2016) · Psychological Medicine · doi:10.1017/s0033291716002981 · Cited by 41
Evidence-based treatment of Tourette’s disorder and chronic tic disorders
Essoe, J. K.-Y., Grados, M. A., Singer, H. S., Myers, N. S., & Mcguire, J. F. (2019) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2019.1643236 · Cited by 41
Self-citation
The colorful spectrum of Tourette syndrome and its medical, surgical and behavioral therapies
Roth, J. (2017) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2017.08.004 · Cited by 40
Altered inter-hemispheric communication of default-mode and visual networks underlie etiology of primary insomnia
Dai, X., Liu, B., Ai, S., Nie, X., Xu, Q., Hu, J., Zhang, Q., Xu, Y., Zhang, Z., & Lu, G. (2019) · Brain Imaging and Behavior · doi:10.1007/s11682-019-00064-0 · Cited by 40
Mouse Models of Neurodevelopmental Disease of the Basal Ganglia and Associated Circuits
Pappas, S. S., Leventhal, D., Albin, R. L., & Dauer, W. T. (2014) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-397920-9.00001-9 · Cited by 41
5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
Fanni, S., Scheggi, S., Rossi, F., Tronci, E., Traccis, F., Stancampiano, R., Montis, M. G. D., Devoto, P., Gambarana, C., Bortolato, M., et al. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.09.018 · Cited by 38
ADHD and Giftedness: A Neurocognitive Consideration of Twice Exceptionality
Budding, D., & Chidekel, D. (2012) · Applied Neuropsychology: Child · doi:10.1080/21622965.2012.699423 · Cited by 35
Nondopaminergic Neurotransmission in the Pathophysiology of Tourette Syndrome
Udvardi, P. T., Nespoli, E., Rizzo, F. R., Hengerer, B., & Ludolph, A. G. (2013) · International review of neurobiology · doi:10.1016/b978-0-12-411546-0.00004-4 · Cited by 37
The Potential of Cannabinoid-Based Treatments in Tourette Syndrome
Artukoglu, B. B., & Bloch, M. H. (2019) · CNS Drugs · doi:10.1007/s40263-019-00627-1 · Cited by 39
Social disinhibition is a heritable subphenotype of tics in Tourette syndrome
Hirschtritt, M. E., Darrow, S. M., Illmann, C., Osiecki, L., Grados, M. A., Sandor, P., Dion, Y., King, R. A., Pauls, D. L., Budman, C. L., et al. (2016) · Neurology · doi:10.1212/wnl.0000000000002910 · Cited by 34
Self-citation
Cingulate role in Tourette syndrome
O’Neill, J., Piacentini, J. C., & Peterson, B. S. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64196-0.00011-x · Cited by 32
Brain functional connectivity in chronic tic disorders and Gilles de la Tourette syndrome
Naro, A., Billeri, L., Colucci, P. V., Cause, M. L., Domenico, C. D., Ciatto, L., Bramanti, P., Bramanti, A., & Calabrò, R. S. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101884 · Cited by 33
The Differential Impact of Tourette's Syndrome and Comorbid Diagnosis on the Quality of Life and Functioning of Diagnosed Children and Adolescents
O'hare, D., Helmes, E., Reece, J., Eapen, V., & McBain, K. (2016) · Journal of Child and Adolescent Psychiatric Nursing · doi:10.1111/jcap.12132 · Cited by 32
Tourette syndrome and obsessive-compulsive disorder: A comprehensive review of structural alterations and neurological mechanisms
Денисовна, Ш. А., Zharikova, T. S., Ковалева, О. Н., Luchina, A. M., Aktemirov, A. S., Olsufieva, A. V., Sinelnikov, M. Y., Pontes‐Silva, A., & Zharikov, Y. O. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114606 · Cited by 35
Inter-hemispheric Intrinsic Connectivity as a Neuromarker for the Diagnosis of Boys with Tourette Syndrome
Liao, W., Yu, Y., Miao, H., Feng, Y.-X., Ji, G., & Feng, J. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9863-9 · Cited by 31
Concordance of genetic variation that increases risk for Tourette Syndrome and that influences its underlying neurocircuitry
Mufford, M. S., Cheung, J. W., Jahanshad, N., van der Merwe, C., Ding, L., Groenewold, N. A., Koen, N., Chimusa, E. R., Dalvie, S., Ramesar, R., et al. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0452-3 · Cited by 30
The basal ganglia
Braunlich, K., & Seger, C. A. (2012) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.1217 · Cited by 33
Variants of Base Excision Repair Genes MUTYH, PARP1 and XRCC1 in Alzheimer's Disease Risk
Kwiatkowski, D., Czarny, P. L., Gałecki, P., Bachurska, A., Talarowska, M. E., Orzechowska, A., Bobińska, K., Bielecka-Kowalska, A., Pietras, T., Szemraj, J., et al. (2015) · Neuropsychobiology · doi:10.1159/000381985 · Cited by 29
VMAT2 Inhibitors in Neuropsychiatric Disorders
Tarakad, A., & Shahed, J. J. (2018) · CNS Drugs · doi:10.1007/s40263-018-0580-y · Cited by 30
Efficacy and safety of traditional Chinese medicine for Tourette's syndrome: A meta-analysis of randomized controlled trials
Qi, H., Liu, R., Zheng, W., Zhang, L., Ungvari, G. S., Ng, C. H., Wang, G., & Xiang, Y. (2019) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2019.101853 · Cited by 29
Effects of obstetric complications on volume and functional connectivity of striatum in anorexia nervosa patients
Favaro, A., Tenconi, E., Degortes, D., Manara, R., & Santonastaso, P. (2014) · International Journal of Eating Disorders · doi:10.1002/eat.22320 · Cited by 28
A functional magnetic resonance imaging investigation of motor control in Gilles de la Tourette syndrome during imagined and executed movements
Zapparoli, L., Porta, M., Gandola, M., Invernizzi, P. L., Colajanni, V., Servello, D., Zerbi, A., Banfi, G., & Paulesu, E. (2015) · European Journal of Neuroscience · doi:10.1111/ejn.13130 · Cited by 28
The Impact of a Cognitive–Behavioral Therapy on Event-Related Potentials in Patients with Tic Disorders or Body-Focused Repetitive Behaviors
Morand‐Beaulieu, S., O’Connor, K. P., Richard, M., Sauvé, G., Leclerc, J. B., Blanchet, P. J., & Lavoie, M. E. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00081 · Cited by 32
Update and recent progress in the neurobiology of Tourette syndrome
Szejko, N. (2022) · International review of movement disorders · doi:10.1016/bs.irmvd.2021.11.003 · Cited by 27
Animal Models Recapitulating the Multifactorial Origin of Tourette Syndrome
Macrì, S., Onori, M. P., Roessner, V., & Laviola, G. (2013) · International review of neurobiology · doi:10.1016/b978-0-12-411546-0.00008-1 · Cited by 28
Histaminergic modulation in Tourette syndrome
Cox, J. H., Seri, S., & Cavanna, A. E. (2015) · Expert Opinion on Orphan Drugs · doi:10.1517/21678707.2016.1128819 · Cited by 26
Sense of agency and its disturbances: A systematic review targeting the intentional binding effect in neuropsychiatric disorders
Moccia, L., Luzio, M. D., Conte, E., Modica, M., Ambrosecchia, M., Ardizzi, M., Lanzotti, P., Kotzalidis, G. D., Janiri, D., Nicola, M. D., et al. (2023) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13601 · Cited by 27
NMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in mice
Sasaki, K., Omotuyi, O. I., Ueda, M., Shinohara, K., & Ueda, H. (2015) · Molecular Brain · doi:10.1186/s13041-015-0176-0 · Cited by 26
The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson's disease
Frau, R., Savoia, P., Fanni, S., Fiorentini, C., Fidalgo, C., Tronci, E., Stancampiano, R., Meloni, M., Cannas, A., Marrosu, F., et al. (2017) · Experimental Neurology · doi:10.1016/j.expneurol.2017.01.012 · Cited by 27
Theoretical and practical considerations behind the use of laboratory animals for the study of Tourette syndrome
Macrı̀, S., Onori, M. P., & Laviola, G. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.03.014 · Cited by 26
Association of ADORA1 rs2228079 and ADORA2A rs5751876 Polymorphisms with Gilles de la Tourette Syndrome in the Polish Population
Janik, P., Berdyński, M., Safranow, K., & Żekanowski, C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136754 · Cited by 25
Investigation of previously implicated genetic variants in chronic tic disorders: a transmission disequilibrium test approach
Abdulkadir, M., Londoño, D., Gordon, D., Fernandez, T. V., Brown, L. W., Cheon, K.-A. A., Coffey, B. J., Elzerman, L., Fremer, C., Fründt, O., et al. (2017) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-017-0808-8 · Cited by 25
Balance within the Neurexin Trans-Synaptic Connexus Stabilizes Behavioral Control
Clarke, R. A., & Eapen, V. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00052 · Cited by 24
Optogenetic Stimulation of GABAergic Neurons in the Globus Pallidus Produces Hyperkinesia
Tian, J., Yan, Y., Wang, X., Zhou, R., Lou, H., Duan, S., Chen, J., & Zhang, B. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00185 · Cited by 23
Voluntary tic suppression and the normalization of motor cortical beta power in Gilles de la Tourette syndrome: an EEG study
Zapparoli, L., Macerollo, A., Joyce, E. M., Martino, D., & Kilner, J. M. (2019) · European Journal of Neuroscience · doi:10.1111/ejn.14548 · Cited by 27
Study of medication‐free children with Tourette syndrome do not show imaging abnormalities
Jeppesen, S. S., Debes, N. M., Simonsen, H. J., Rostrup, E., Larsson, H. B. W., & Skov, L. (2014) · Movement Disorders · doi:10.1002/mds.25858 · Cited by 23
The future of tic disorder treatment
Bennett, S. M., Keller, A. E., & Walkup, J. T. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12296 · Cited by 20
Electrophysiological predictors of cognitive-behavioral therapy outcome in tic disorders
Morand‐Beaulieu, S., O’Connor, K. P., Blanchet, P. J., & Lavoie, M. E. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.08.020 · Cited by 20
Impaired forward model updating in young adults with Tourette syndrome
Kim, S., Jackson, G. M., Dyke, K., & Jackson, S. R. (2018) · Brain · doi:10.1093/brain/awy306 · Cited by 22
Executive function in children with Tourette syndrome and attention-deficit/hyperactivity disorder: Cross-disorder or unique impairments?
Openneer, T. J. C., Forde, N. J., Akkermans, S. E. A., Naaijen, J., Buitelaar, J. K., Hoekstra, P. J., & Dietrich, A. (2019) · Cortex · doi:10.1016/j.cortex.2019.11.007 · Cited by 20
Altered structural cerebral cortex in children with Tourette syndrome
Kong, L., Lv, B., Wu, T., Zhang, J., Yang, F., Ouyang, M., Huang, H., Peng, Y., & Liu, Y. (2020) · European Journal of Radiology · doi:10.1016/j.ejrad.2020.109119 · Cited by 21
Histaminergic Control of Corticostriatal Synaptic Plasticity during Early Postnatal Development
Han, S., Márquez-Gómez, R., Woodman, M. J., & Ellender, T. J. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.0740-20.2020 · Cited by 19
The role of neuroactive steroids in tic disorders
Branca, C., & Bortolato, M. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105637 · Cited by 21
Basal ganglia structure in Tourette's disorder and/or attention‐deficit/hyperactivity disorder
Forde, N., Zwiers, M., Naaijen, J., Akkermans, S., Openneer, T. J. C., Visscher, F., Dietrich, A., Buitelaar, J., & Hoekstra, P. (2017) · Movement Disorders · doi:10.1002/mds.26849 · Cited by 18
GDNF gene is associated with tourette syndrome in a family study
Huertas‐Fernández, I., Gómez‐Garre, P., Madruga‐Garrido, M., Bernal‐Bernal, I., Bonilla‐Toribio, M., Martin‐Rodríguez, J. F., Cáceres‐Redondo, M. T., Vargas‐González, L., Carrillo, F., Pascual, A., et al. (2015) · Movement Disorders · doi:10.1002/mds.26279 · Cited by 18
Behavioral and stereological characterization of Hdc KO mice: Relation to Tourette syndrome
Abdurakhmanova, S., Chary, K., Kettunen, M. I., Sierra, A., & Panula, P. (2017) · The Journal of Comparative Neurology · doi:10.1002/cne.24279 · Cited by 18
Functional Evaluations of Genes Disrupted in Patients with Tourette’s Disorder
Sun, N., Tischfield, J. A., King, R. A., & Heiman, G. A. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00011 · Cited by 17
Genetic architecture of Tourette syndrome: our current understanding
Domènech, L., Cappi, C., & Halvorsen, M. (2021) · Psychological Medicine · doi:10.1017/s0033291721000234 · Cited by 18
Olfactory functioning in adults with Tourette syndrome
Kronenbuerger, M., Belenghi, P., Ilgner, J. F. R., Freiherr, J., Hummel, T. R., & Neuner, I. (2018) · PLoS ONE · doi:10.1371/journal.pone.0197598 · Cited by 17
Biomarkers and Tourette syndrome: a systematic review and meta-analysis
Jiang, Y., Li, Y., Chen, X., Zhai, R., Peng, Y., Tai, R., Zhou, C., & Wang, J. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1262057 · Cited by 23

Authors: Felling, R. J., & Singer, H. S.
Affiliations: Johns Hopkins University (US)
Corresponding author: Singer, Harvey S.
ORCID: Felling, Ryan J.
Singer, Harvey S.
Venue: The Journal of Neuroscience
Publisher: Society for Neuroscience
Published: 2011-08-31
Volume: 31
Issue: 35
Pages: 12387-12395
ISSN: 0270-6474 (ISSN-L)
1529-2401
DOI: 10.1523/jneurosci.0150-11.2011
PMC: PMC6703258
OpenAlex: W1970375293
Cited by: 227
References: 138
Citations by year: 2026: 8 · 2025: 12 · 2024: 13 · 2023: 14 · 2022: 7 · 2021: 8 · 2020: 20 · 2019: 16 · 2018: 17 · 2017: 24 · 2016: 26 · 2015: 22 · 2014: 16 · 2013: 18 · 2012: 6
FWCI: 13.61
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-sa
creativecommons.org/licenses/by-nc-sa/4.0/ (vor, 182 d)
Locations: Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Social Sciences › Psychology › Clinical Psychology › Stuttering Research and Treatment
Keywords: Tourette syndrome, neurobiology, dopaminergic dysfunction, tics, genetic inheritance, comorbidities, neurotransmitters, neuroimaging
MeSH terms: Animals, Disease Models, Animal, Tourette Syndrome, Humans, Neurobiology, History, 19th Century

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Neurobiology of Tourette Syndrome: Current Status and Need for Further Investigation: Table 1.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks