Analysis of Knock-Out Mice to Determine the Role of HPC-1/Syntaxin 1A in Expressing Synaptic Plasticity

SNAP receptors implicated in vesicle targeting and fusion

Söllner, T. H., Whiteheart, S. W., Brunner, M., Erdjument‐Bromage, H., Geromanos, S. J., Tempst, P., & Rothman, J. E. (1993) · Nature · doi:10.1038/362318a0 · Cited by 3,239

The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review.

Prut, L., & Belzung, C. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01272-x · Cited by 3,190

Long-Term Potentiation--A Decade of Progress?

Malenka, R. C., & Nicoll, A. R. A. (1999) · Science · doi:10.1126/science.285.5435.1870 · Cited by 2,729

Applications of the Morris water maze in the study of learning and memory

D’Hooge, R., & Deyn, P. P. D. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00067-4 · Cited by 2,083

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

Bennett, M. K., Calakos, N., & Scheller, R. H. (1992) · Science · doi:10.1126/science.1321498 · Cited by 1,263

Cleavage of proBDNF by tPA/Plasmin Is Essential for Long-Term Hippocampal Plasticity

Pang, P. T., Teng, H. K., Zaitsev, E., Woo, N. T., Sakata, K., Zhen, S., Teng, K. K., Yung, W.-H., Hempstead, B. L., & Lu, B. (2004) · Science · doi:10.1126/science.1100135 · Cited by 1,136

Postsynaptic signaling and plasticity mechanisms

Sheng, M., & Kim, M. J. (2002) · Science · doi:10.1126/science.1075333 · Cited by 731

Profound neuronal plasticity in response to inactivation of the dopamine transporter

Jones, S. R., Gainetdinov, R. R., Jaber, M., Giros, B., Wightman, R. M., & Caron, M. G. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.7.4029 · Cited by 712

Abnormal Spine Morphology and Enhanced LTP in LIMK-1 Knockout Mice

Meng, Y., Zhang, Y., Tregoubov, V., Janus, C., Cruz, L., Jackson, M., Lu, W.-Y., MacDonald, J. F., Wang, J. Y., Falls, D. L., et al. (2002) · Neuron · doi:10.1016/s0896-6273(02)00758-4 · Cited by 688

SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice

Schoch, S., Deák, F., Königstorfer, A., Mozhayeva, M. G., Sara, Y., Südhof, T. C., & Kavalali, E. T. (2001) · Science · doi:10.1126/science.1064335 · Cited by 664

Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism

Sanders, S. J., Ercan-Sencicek, A. G., Hus, V., Luo, R., Murtha, M. T., Moreno-De-Luca, D., Chu, S. H., Moreau, M. P., Gupta, A. R., Thomson, S. A., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.002 · Cited by 1,263

The genomic basis of the Williams – Beuren syndrome

Schubert, C. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8401-y · Cited by 245

Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis

Ohara-Imaizumi, M., Fujiwara, T., Nakamichi, Y., Okamura, T., Akimoto, Y., Kawai, J., Matsushima, S., Kawakami, H., Watanabe, T., Akagawa, K., et al. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200608132 · Cited by 211

Open Syntaxin Docks Synaptic Vesicles

Hammarlund, M., Palfreyman, M. T., Watanabe, S., Olsen, S. R., & Jørgensen, E. M. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050198 · Cited by 201

Glutamate and GABA synthesis, release, transport and metabolism as targets for seizure control

Rowley, N. M., Madsen, K. K., Schousboe, A., & White, H. S. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.02.013 · Cited by 211

Curcumin Enhances Neurogenesis and Cognition in Aged Rats: Implications for Transcriptional Interactions Related to Growth and Synaptic Plasticity

Dong, S., Zeng, Q., Mitchell, E. S., Xiu, J., Duan, Y., Li, C., Tiwari, J. K., Hu, Y., Cao, X., & Zhao, Z. Y. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031211 · Cited by 179

Copy number variants at Williams–Beuren syndrome 7q11.23 region

Merla, G., Brunetti‐Pierri, N., Micale, L., & Fusco, C. (2010) · Human Genetics · doi:10.1007/s00439-010-0827-2 · Cited by 159

Syntabulin–Kinesin-1 Family Member 5B-Mediated Axonal Transport Contributes to Activity-Dependent Presynaptic Assembly

Cai, Q., Pan, P., & Sheng, Z. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0731-07.2007 · Cited by 152

SNAREopathies: Diversity in Mechanisms and Symptoms

Verhage, M., & Sørensen, J. B. (2020) · Neuron · doi:10.1016/j.neuron.2020.05.036 · Cited by 121

Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4

Jewell, J. L., Oh, E., & Thurmond, D. C. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00597.2009 · Cited by 127

Differential Effects of SNAP-25 Deletion on Ca2+-Dependent and Ca2+-Independent Neurotransmission

Bronk, P., Deák, F., Wilson, M. C., Liu, X., Südhof, T. C., & Kavalali, E. T. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00226.2007 · Cited by 126

A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse

Jeans, A. F., Oliver, P. L., Johnson, R., Capogna, M., Vikman, J., Molnár, Z., Babbs, A., Partridge, C. J., Salehi, A. A., Bengtsson, M., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610222104 · Cited by 122

Endosomal and Phagosomal SNAREs

Dingjan, I., Linders, P. T. A., Verboogen, D. R. J., Revelo, N. H., ter Beest, M., & van den Bogaart, G. (2018) · Physiological Reviews · doi:10.1152/physrev.00037.2017 · Cited by 114

Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1‐targeted mice

Young, E. J., Lipina, T. V., Tam, E., Mandel, A., Clapcote, S. J., Bechard, A. R., Chambers, J., Mount, H. T. J., Fletcher, P. J., Roder, J., et al. (2007) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2007.00343.x · Cited by 109

Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons

Vardar, G., Chang, S., Arancillo, M., Wu, Y.-J., Trimbuch, T., & Rosenmund, C. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1314-16.2016 · Cited by 108

Induced chromosome deletions cause hypersociability and other features of Williams–Beuren syndrome in mice

Li, H. H., Roy, M., Kusçuoglu, U., Spencer, C. M., Halm, B., Harrison, K. C., Bayle, J. H., Splendore, A., Ding, F., Meltzer, L. A., et al. (2009) · EMBO Molecular Medicine · doi:10.1002/emmm.200900003 · Cited by 107

Cognitive reserve, presynaptic proteins, and dementia in the elderly

Honer, W. G., Barr, A. M., Sawada, K., Thornton, A. E., Morris, M. C., Leurgans, S. E., Schneider, J. A., & Bennett, D. A. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.38 · Cited by 100

Biomarker-based dissection of neurodegenerative diseases

Olsson, B., Zetterberg, H., Hampel, H. J., & Blennow, K. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.04.006 · Cited by 102

Munc18-1 Is Critical for Plasma Membrane Localization of Syntaxin1 but Not of SNAP-25 in PC12 Cells

Arunachalam, L., Han, L., Tassew, N. G., He, Y., Wang, L., Xie, L., Fujita, Y., Kwan, E. P., Davletov, B. A., Monnier, P. P., et al. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-07-0662 · Cited by 93

Syntaxin 1B, but Not Syntaxin 1A, Is Necessary for the Regulation of Synaptic Vesicle Exocytosis and of the Readily Releasable Pool at Central Synapses

Mishima, T., Fujiwara, T., Sanada, M., Kofuji, T., Kanai‐Azuma, M., & Akagawa, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090004 · Cited by 89

Vesicular traffic in cell navigation

Zylbersztejn, K., & Galli, T. (2011) · FEBS Journal · doi:10.1111/j.1742-4658.2011.08168.x · Cited by 88

Titration of Syntaxin1 in Mammalian Synapses Reveals Multiple Roles in Vesicle Docking, Priming, and Release Probability

Arancillo, M., Min, S., Gerber, S., Münster‐Wandowski, A., Wu, Y.-J., Herman, M. A., Trimbuch, T., Rah, J., Ahnert‐Hilger, G., Riedel, D., et al. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0187-13.2013 · Cited by 78

Interaction between environmental and genetic factors modulates schizophrenic endophenotypes in the Snap-25 mouse mutant blind-drunk

Oliver, P. L., & Davies, K. E. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp425 · Cited by 78

The involvement of actin, calcium channels and exocytosis proteins in somato-dendritic oxytocin and vasopressin release

Tobin, V. A., Leng, G., & Ludwig, M. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00261 · Cited by 70

Animal models of Williams syndrome

Osborne, L. R. (2010) · American Journal of Medical Genetics Part C Seminars in Medical Genetics · doi:10.1002/ajmg.c.30257 · Cited by 72

Disorders of synaptic vesicle fusion machinery

Melland, H., Arvell, E. H., & Gordon, S. L. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15181 · Cited by 66

Impaired cognition, sensorimotor gating, and hippocampal long-term depression in mice lacking the prostaglandin E2 EP2 receptor

Savonenko, A., Muñoz, P., Melnikova, T., Wang, Q., Liang, X., Breyer, R., Montine, T., Kirkwood, A., & Andreasson, K. I. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.01.016 · Cited by 70

A Signaling Mechanism Coupling Netrin-1/Deleted in Colorectal Cancer Chemoattraction to SNARE-Mediated Exocytosis in Axonal Growth Cones

Cotrufo, T., Pérez‐Brangulí, F., Muhaisen, A., Ros, O., Andrés, R. M., Baeriswyl, T., Fuschini, G., Tarragó, T., Pascual, M., Ureña, J. M., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3018-11.2011 · Cited by 63

LIM-Kinases in Synaptic Plasticity, Memory, and Brain Diseases

Zablah, Y. B., Zhang, H., Gugustea, R., & Jia, Z. (2021) · Cells · doi:10.3390/cells10082079 · Cited by 58

Leaky synapses: Regulation of spontaneous neurotransmission in central synapses

Wasser, C. R., & Kavalali, E. T. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.03.028 · Cited by 55

Plasticity-related microRNA and their potential contribution to the maintenance of long-term potentiation

Ryan, B., Joilin, G., & Williams, J. M. (2015) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2015.00004 · Cited by 62

Molecular mechanisms of synaptogenesis

Qi, C., Luo, L.-D., Feng, I., & Ma, S. (2022) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2022.939793 · Cited by 54

Diabetes differentially affects the content of exocytotic proteins in hippocampal and retinal nerve terminals

Gaspar, J. M., Baptista, F. I., Galvão, J., Castilho, Á., Cunha, R. A., & Ambrósio, A. F. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.06.021 · Cited by 53

Regulation of SNARE-Mediated Membrane Fusion during Exocytosis

McNew, J. A. (2008) · Chemical Reviews · doi:10.1021/cr0782325 · Cited by 51

Endosomal Fusion upon SNARE Knockdown is Maintained by Residual SNARE Activity and Enhanced Docking

Bethani, I., Werner, A. A., Kadian, C., Geumann, U., Jahn, R., & Rizzoli, S. O. (2009) · Traffic · doi:10.1111/j.1600-0854.2009.00959.x · Cited by 48

HPC ‐1/syntaxin 1A and syntaxin 1B play distinct roles in neuronal survival

Kofuji, T., Fujiwara, T., Sanada, M., Mishima, T., & Akagawa, K. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12722 · Cited by 45

Syntaxin 1B is important for mouse postnatal survival and proper synaptic function at the mouse neuromuscular junctions

Wu, Y.-J., Tejero, R., Arancillo, M., Vardar, G., Korotkova, T. M., Kintscher, M., Schmitz, D., Ponomarenko, A. A., Tabares, L., & Rosenmund, C. (2015) · Journal of Neurophysiology · doi:10.1152/jn.00577.2015 · Cited by 44

Heterogeneity of glutamatergic and GABAergic release machinery in cerebral cortex: analysis of synaptogyrin, vesicle-associated membrane protein, and syntaxin

Bragina, L., Giovedì, S., Barbaresi, P., Benfenati, F., & Conti, F. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.11.009 · Cited by 44

Intelligence in Williams Syndrome is related to STX1A, which encodes a component of the presynaptic SNARE complex

Gao, M. C., Bellugi, U., Dai, L., Mills, D. L., Sobel, E. M., Lange, K., & Korenberg, J. R. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010292 · Cited by 42

Calcium Regulates Molecular Interactions of Otoferlin with Soluble NSF Attachment Protein Receptor (SNARE) Proteins Required for Hair Cell Exocytosis

Ramakrishnan, N. A., Drescher, M. J., Morley, B. J., Kelley, P. M., & Drescher, D. G. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.480533 · Cited by 41

New Roles of Syntaxin-1A in Insulin Granule Exocytosis and Replenishment

Liang, T., Qin, T., Xie, L., Dolai, S., Zhu, D. Y., Prentice, K. J., Wheeler, M. B., Kang, Y., Osborne, L. R., & Gaisano, H. Y. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.769885 · Cited by 39

Dynamin 1 Is Required for Memory Formation

Fà, M., Staniszewski, A., Saeed, F., Francis, Y. I., & Arancio, O. (2014) · PLoS ONE · doi:10.1371/journal.pone.0091954 · Cited by 39

Deletion of SNAP-23 Results in Pre-Implantation Embryonic Lethality in Mice

Suh, Y. H., Yoshimoto-Furusawa, A., Weih, K. A., Tessarollo, L., Roche, K. W., Mackem, S., & Roche, P. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018444 · Cited by 37

Bisphenol A Exposure in utero Disrupts Hypothalamic Gene Expression Particularly Genes Suspected in Autism Spectrum Disorders and Neuron and Hormone Signaling

Henriksen, A. D. P., Andrade, A., Harris, E. P., Rissman, E. F., & Wolstenholme, J. T. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093129 · Cited by 37

Robust syntaxin-4 immunoreactivity in mammalian horizontal cell processes

Hirano, A. A., Brandstätter, J. H., VILA, A., & Brecha, N. C. (2007) · Visual Neuroscience · doi:10.1017/s0952523807070198 · Cited by 37

SNAREs and developmental disorders

Tang, B. L. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.30067 · Cited by 33

Membrane Trafficking in Neuronal Development: Ins and Outs of Neural Connectivity

Winkle, C. C., & Gupton, S. L. (2016) · International review of cytology · doi:10.1016/bs.ircmb.2015.10.003 · Cited by 35

The presynaptic machinery at the synapse of C. elegans

Calahorro, F., & Izquierdo, P. G. (2018) · Invertebrate Neuroscience · doi:10.1007/s10158-018-0207-5 · Cited by 40

Syntaxin Requirement for Ca2+-Triggered Exocytosis in Neurons and Endocrine Cells Demonstrated with an Engineered Neurotoxin

Wang, D., Zhang, Z., Dong, M., Sun, S., Chapman, E. R., & Jackson, M. B. (2011) · Biochemistry · doi:10.1021/bi200290p · Cited by 32

SNARE Function Is Not Involved in Early Endosome Docking

Geumann, U., Barysch, S. V., Hoopmann, P., Jahn, R., & Rizzoli, S. O. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-05-0457 · Cited by 31

Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: Further characterization of presynaptic mechanisms

Matsuzawa, R., Fujiwara, T., Nemoto, K., Fukushima, T., Yamaguchi, S., Akagawa, K., & Hori, Y. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.11.017 · Cited by 29

HPC‐1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5‐HTergic systems

Fujiwara, T., Snada, M., Kofuji, T., Yoshikawa, T., & Akagawa, K. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07269.x · Cited by 29

Impairment of Catecholamine Systems during Induction of Long-Term Potentiation at Hippocampal CA1 Synapses in HPC-1/Syntaxin 1A Knock-out Mice

Mishima, T., Fujiwara, T., Kofuji, T., & Akagawa, K. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2911-11.2012 · Cited by 29

Cognitive deficits in mice lacking Nsun5, a cytosine‐5 RNA methyltransferase, with impairment of oligodendrocyte precursor cells

Zhang, T., Chen, P., Li, W., Sha, S., Wang, Y., Yuan, Z., Shen, B., & Chen, L. (2018) · Glia · doi:10.1002/glia.23565 · Cited by 30

Epilepsy-causing STX1B mutations translate altered protein functions into distinct phenotypes in mouse neurons

Vardar, G., Gerth, F., Schmitt, X. J., Rautenstrauch, P., Trimbuch, T., Schubert, J., Lerche, H., Rosenmund, C., & Freund, C. (2020) · Brain · doi:10.1093/brain/awaa151 · Cited by 29

Mapping Genetically Controlled Neural Circuits of Social Behavior and Visuo-Motor Integration by a Preliminary Examination of Atypical Deletions with Williams Syndrome

Hoeft, F., Dai, L., Haas, B. W., Sheau, K. E., Mimura, M., Mills, D. L., Galaburda, A. M., Bellugi, U., Korenberg, J. R., & Reiss, A. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104088 · Cited by 28

Unusual social behavior in HPC‐1/syntaxin1A knockout mice is caused by disruption of the oxytocinergic neural system

Fujiwara, T., Sanada, M., Kofuji, T., & Akagawa, K. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13634 · Cited by 27

Microduplication of Xp11.23p11.3 with effects on cognition, behavior, and craniofacial development

El‐Hattab, A. W., Bournat, J. C., Eng, P., Wu, J., Walker, B., Stankiewicz, P., Cheung, S., & Brown, C. (2010) · Clinical Genetics · doi:10.1111/j.1399-0004.2010.01496.x · Cited by 25

Loss of Granuphilin and Loss of Syntaxin-1A Cause Differential Effects on Insulin Granule Docking and Fusion

Wang, H., Ishizaki, R., Kobayashi, E., Fujiwara, T., Akagawa, K., & Izumi, T. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.268631 · Cited by 25

Synaptic plasticity and spatial working memory are impaired in the CD mouse model of Williams-Beuren syndrome

Borralleras, C., Mato, S., Amédée, T., Matute, C., Mulle, C., Jurado, L. A. P., & Campuzano, V. (2016) · Molecular Brain · doi:10.1186/s13041-016-0258-7 · Cited by 23

Neonatal exposure to BDE 209 impaired learning and memory, decreased expression of hippocampal core SNAREs and synaptophysin in adult rats

Li, X., Wang, C., Wang, W., Yue, C., & Tang, Y. M. (2017) · NeuroToxicology · doi:10.1016/j.neuro.2017.01.004 · Cited by 24

Sequential steps underlying neuronal plasticity induced by a transient exposure to gabazine

Pegoraro, S., Broccard, F. D., Ruaro, M. E., Bianchini, D., Avossa, D., Pastore, G., Bisson, G., Altafini, C., & Torre, V. (2009) · Journal of Cellular Physiology · doi:10.1002/jcp.21998 · Cited by 25

SNARE complex in axonal guidance and neuroregeneration

Araújo, S. J., Ulloa, F., Cotrufo, T., Ricolo, D., & Soriano, E. (2018) · Neural Regeneration Research · doi:10.4103/1673-5374.228710 · Cited by 26

Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells

Sakurai, T., Kitadate, K., Nishioka, H., Fujii, H., Ogasawara, J., Kizaki, T., Sato, S., Fujiwara, T., Akagawa, K., Izawa, T., et al. (2013) · British Journal Of Nutrition · doi:10.1017/s000711451300086x · Cited by 22

Enzyme-treated Asparagus officinalis Extract Shows Neuroprotective Effects and Attenuates Cognitive Impairment in Senescence-accelerated Mice

Sakurai, T., Ito, T., Wakame, K., Kitadate, K., Arai, T., Ogasawara, J., Kizaki, T., Sato, S., Ishibashi, Y., Fujiwara, T., et al. (2014) · Natural Product Communications · doi:10.1177/1934578x1400900130 · Cited by 22

Genetic disorders of neurotransmitter release machinery

Uzay, B., & Kavalali, E. T. (2023) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2023.1148957 · Cited by 19

Behavioral Analysis of SNAP-25 and Synaptobrevin-2 Haploinsufficiency in Mice

Monteggia, L. M., Lin, P.-Y., Adachi, M., & Kavalali, E. T. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.08.014 · Cited by 18

A conserved role for Syntaxin-1 in pre- and post-commissural midline axonal guidance in fly, chick, and mouse

Ros, O., Barrecheguren, P. J., Cotrufo, T., Schaettin, M., Roselló-Busquets, C., Vílchez-Acosta, A., Hernaiz-Llorens, M., Martínez‐Mármol, R., Ulloa, F., Stoeckli, E. T., et al. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007432 · Cited by 18

Fast, Ca2+-dependent exocytosis at nerve terminals: Shortcomings of SNARE-based models

Meriney, S. D., Umbach, J. A., & Gundersen, C. B. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2014.07.001 · Cited by 18

SNAP23 deficiency causes severe brain dysplasia through the loss of radial glial cell polarity

Kunii, M., Noguchi, Y., Yoshimura, S., Kanda, S., Iwano, T., Avriyanti, E., Atik, N., Sato, T., Sato, K., Ogawa, M., et al. (2020) · The Journal of Cell Biology · doi:10.1083/jcb.201910080 · Cited by 16

A part of patients with autism spectrum disorder has haploidy of HPC-1/syntaxin1A gene that possibly causes behavioral disturbance as in experimentally gene ablated mice

Kofuji, T., Hayashi, Y., Fujiwara, T., Sanada, M., Tamaru, M., & Akagawa, K. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.02.052 · Cited by 17

Syntaxin 1A is required for normal in utero development

McRory, J. E., Rehak, R., Simms, B., Doering, C. J., Chen, L., Hermosilla, T., Duke, C., Dyck, R. H., & Zamponi, G. W. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.08.031 · Cited by 17

Modeling Williams syndrome with induced pluripotent stem cells

Chailangkarn, T., & Muotri, A. R. (2017) · Neurogenesis · doi:10.1080/23262133.2017.1283187 · Cited by 18

Genome-wide DNA methylation changes associated with olfactory learning and memory in Apis mellifera

Li, Y., Zhang, L.-Z., Yi, Y., Hu, W.-W., Guo, Y.-J., Zeng, Z., Huang, Z.-Y., & Wang, Z. (2017) · Scientific Reports · doi:10.1038/s41598-017-17046-1 · Cited by 18

Syntaxin 1B regulates synaptic GABA release and extracellular GABA concentration, and is associated with temperature‐dependent seizures

Mishima, T., Fujiwara, T., Kofuji, T., Saito, A., Terao, Y., & Akagawa, K. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15159 · Cited by 14

Conformational states of syntaxin-1 govern the necessity of N-peptide binding in exocytosis of PC12 cells and Caenorhabditis elegans

Park, S., Bin, N., Rajah, M. M., Kim, B., Chou, T.-C., Kang, S.-Y. A., Sugita, K., Parsaud, L., Smith, M. J., Monnier, P. P., et al. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-09-0638 · Cited by 14

Functional regulation of syntaxin-1: An underlying mechanism mediating exocytosis in neuroendocrine cells

Yang, X., Tu, W., Gao, X., Zhang, Q., Guan, J., & Zhang, J. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1096365 · Cited by 13

Dysfunction of the Hypothalamic-Pituitary-Adrenal axis in STX1A Knockout Mice

Fujiwara, T., Kofuji, T., & Akagawa, K. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02214.x · Cited by 14

Postsynaptic Protein Shank3a Deficiency Synergizes with Alzheimer's Disease Neuropathology to Impair Cognitive Performance in the 3xTg-AD Murine Model

Landry, O., François, A., Mi-mba, M.-F. O. M., Traversy, M.-T., Tremblay, C., Émond, V., Bennett, D. A., Gylys, K. H., Buxbaum, J. D., & Calon, F. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.1945-22.2023 · Cited by 14

Differential protein expression analysis following olfactory learning in Apis cerana

Zhang, L., Yan, W., Wang, Z., Guo, Y.-J., Yi, Y., Zhang, S.-W., & Zeng, Z. (2015) · Journal of Comparative Physiology A · doi:10.1007/s00359-015-1042-3 · Cited by 13

Enhancement of synaptic transmission and nociceptive behaviour in HPC‐1/syntaxin 1A knockout mice following peripheral nerve injury

Takasusuki, T., Fujiwara, T., Yamaguchi, S., Fukushima, T., Akagawa, K., & Hori, Y. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05830.x · Cited by 14

Syntaxin-1a and SNAP-25 expression level is increased in the blood samples of ischemic stroke patients

Cappelletti, P., Filareti, M., Masuelli, L., Bei, R., Hassanzadeh, K., Corbo, M., & Feligioni, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-18719-2 · Cited by 12

STX1A gene variations contribute to the susceptibility of children attention-deficit/hyperactivity disorder: a case–control association study

Wang, M., Gu, X., Huang, X., Zhang, Q., Chen, X., & Wu, J. (2019) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-019-01010-3 · Cited by 13

Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1) in the attenuation of cognitive impairment by exercise training

Sakurai, T., Ogasawara, J., Kizaki, T., Ishibashi, Y., Fujiwara, T., Akagawa, K., Izawa, T., Oh‐ishi, S., Haga, S., & Ohno, H. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.11.008 · Cited by 12

Molecular characterization and gene expression of syntaxin-1 and VAMP2 in the olfactory organ and brain during both seaward and homeward migrations of chum salmon, Oncorhynchus keta.

Abe, T., & Kudo, H. (2019) · Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · doi:10.1016/j.cbpa.2018.09.008 · Cited by 8

SNARE Proteins in Synaptic Vesicle Fusion

Palfreyman, M. T., West, S. E., & Jørgensen, E. M. (2023) · Advances in neurobiology · doi:10.1007/978-3-031-34229-5_4 · Cited by 10

The role of syntaxins in retinal function and health

Tebbe, L., Kakakhel, M., Al‐Ubaidi, M. R., & Naash, M. I. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1380064 · Cited by 9

Roles of SNARE Proteins in Synaptic Vesicle Fusion

Palfreyman, M. T., & Jørgensen, E. M. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-481-0_3 · Cited by 9

Syntaxin 1B contributes to regulation of the dopaminergic system through GABA transmission in the CNS

Fujiwara, T., Kofuji, T., Mishima, T., & Akagawa, K. (2017) · European Journal of Neuroscience · doi:10.1111/ejn.13779 · Cited by 10

The synaptosome‐associated protein 23 ( SNAP23 ) is necessary for proper myogenesis

Gentile, G. M., Gamarra, J. R., Engels, N. M., Blue, R. E., Hoerr, I., Wiedner, H. J., Hinkle, E. R., Cote, J. L., Leverence, E. N., Mills, C. A., et al. (2022) · The FASEB Journal · doi:10.1096/fj.202101627rr · Cited by 8

Investigating the Role of SNARE Proteins in Trafficking of Postsynaptic Receptors using Conditional Knockouts

Bin, N., Huang, M., & Sugita, S. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.11.027 · Cited by 8

Vesicle trafficking with snares: a perspective for autism

Özdemir, Ç., Şahın, N., & Edgünlü, T. (2022) · Molecular Biology Reports · doi:10.1007/s11033-022-07970-5 · Cited by 9

The cell‐ and tissue‐specific transcription mechanism of the TATA‐less syntaxin 1A gene

Nakayama, T. W., Mikoshiba, K., & Akagawa, K. (2015) · The FASEB Journal · doi:10.1096/fj.15-275529 · Cited by 8

Tracking Single Molecule Dynamics in the Adult Drosophila Brain

Hines, A., & van Swinderen, B. (2021) · eNeuro · doi:10.1523/eneuro.0057-21.2021 · Cited by 8

Disturbance of the reciprocal-interaction between the OXTergic and DAergic systems in the CNS causes atypical social behavior in syntaxin 1A knockout mice

Fujiwara, T., Kofuji, T., & Akagawa, K. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113447 · Cited by 6

Unusual retinal layer organization in HPC-1/syntaxin 1A knockout mice

Kaneko, Y., Suge, R., Fujiwara, T., Akagawa, K., & Watanabe, S. (2011) · Journal of Molecular Histology · doi:10.1007/s10735-011-9346-2 · Cited by 6

Distinct Genetic Signatures of Cortical and Subcortical Regions Associated with Human Memory

Tan, P. K., Ananyev, E., & Hsieh, P. (2019) · eNeuro · doi:10.1523/eneuro.0283-19.2019 · Cited by 9

Syntaxin-1 is necessary for UNC5A-C/Netrin-1-dependent macropinocytosis and chemorepulsion

Martínez‐Mármol, R., Muhaisen, A., Cotrufo, T., Roselló-Busquets, C., Ros, O., Hernaiz-Llorens, M., Pérez‐Brangulí, F., Andrés, R. M., Parcerisas, A., Pascual, M., et al. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1253954 · Cited by 6

Heterogeneity of presynaptic proteins: do not forget isoforms

Bragina, L., Fattorini, G., Giovedı̀, S., Bosco, F., Benfenati, F., & Conti, F. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00008 · Cited by 6

Frankincense improves memory retrieval and down-regulates the hippocampal synaptophysin mRNA during the development of the rat brain

Beheshti, S., Tohidloo, S., & Esmaeili, A. (2019) · Physiology and Pharmacology · doi:10.32598/ppj.24.1.60 · Cited by 5

Impairment of Catecholamine Systems during Induction of Long-Term Potentiation at Hippocampal CA1 Synapses in HPC-1/Syntaxin 1A Knock-out Mice

Mishima, T., Fujiwara, T., Kofuji, T., & Akagawa, K. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2911-11.2012 · Cited by 29

Impaired induction of long-term potentiation in HPC-1/syntaxin 1A knockout mice may be due to altered cAMP/PKA signaling

Mishima, T., Fujiwara, T., Kofuji, T., & Akagawa, K. (2009) · Neuroscience Research · doi:10.1016/j.neures.2009.09.313

Enhancement of neurite-sprouting by suppression of HPC-1/syntaxin 1A activity in cultured vertebrate nerve cells

Yamaguchi, K., Nakayama, T., Fujiwara, T., & Akagawa, K. (1996) · Brain Research · doi:10.1016/s0006-8993(96)00861-x · Cited by 32

Enhancement of synaptic transmission by HPC-1 antibody in the cultured hippocampal neuron

Yamaguchi, K., Takada, M., 久美子, 藤., Tsuchimoto, Y., Kushima, Y., Sanada, M., Fujiwara, T., & Akagawa, K. (1997) · Neuroreport · doi:10.1097/00001756-199711100-00043 · Cited by 13

Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.

Lledo, P., Tremblay, P., DeArmond, S. J., Prusiner, S. B., & Nicoll, R. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.6.2403 · Cited by 224