LEF1/β-Catenin Complex Regulates Transcription of the Cav3.1 Calcium Channel Gene (Cacna1g) in Thalamic Neurons of the Adult Brain

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Maxam, A. M., & Gilbert, W. (1980) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(80)65059-9 · Cited by 14,678 · see citing works

International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

Catterall, W. A., Chandy, K. G., Clapham, D. E., Gutman, G. A., Hofmann, F., Harmar, A. J., Abernethy, D. R., & Spedding, M. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.4.5 · Cited by 7,126 · see citing works

Wnt/β-Catenin Signaling in Development and Disease

Clevers, H. (2006) · Cell · doi:10.1016/j.cell.2006.10.018 · Cited by 5,568 · see citing works

VISTA: computational tools for comparative genomics

Frazer, K. A., Pachter, L. S., Poliakov, A., Rubin, E. M., & Dubchak, I. L. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh458 · Cited by 2,791 · see citing works

International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels

Catterall, W. A., Goldin, A. L., & Waxman, S. G. (2005) · Pharmacological Reviews · doi:10.1124/pr.57.4.4 · Cited by 2,259 · see citing works

Molecular Physiology of Low-Voltage-Activated T-type Calcium Channels

Perez‐Reyes, E. (2003) · Physiological Reviews · doi:10.1152/physrev.00018.2002 · Cited by 1,655 · see citing works

Wnt signalling regulates adult hippocampal neurogenesis

Lie, D. C., Colamarino, S. A., Song, H., Désiré, L., Mira, H., Consiglio, A., Lein, E. S., Jessberger, S., Lansford, H., Dearie, A. R., et al. (2005) · Nature · doi:10.1038/nature04108 · Cited by 1,510 · see citing works

Regulation of Cerebral Cortical Size by Control of Cell Cycle Exit in Neural Precursors

Chenn, A., & Walsh, C. A. (2002) · Science · doi:10.1126/science.1074192 · Cited by 1,431 · see citing works

Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements

Veeman, M. T., Slusarski, D. C., Kaykas, A., Louie, S. H., & Moon, R. T. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00240-9 · Cited by 945 · see citing works

Tonic and burst firing: dual modes of thalamocortical relay.

Sherman, S. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01714-8 · Cited by 796 · see citing works

Differential Distribution of Three Members of a Gene Family Encoding Low Voltage-Activated (T-Type) Calcium Channels

Talley, E. M., Cribbs, L. L., Lee, J., Daud, A. N., Perez‐Reyes, E., & Bayliss, D. A. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-06-01895.1999 · Cited by 790 · see citing works

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

Mao, Y., Ge, X., Frank, C. L., Madison, J. M., Koehler, A. N., Doud, M. K., Tassa, C., Berry-Scott, E., Soda, T., Singh, K. K., et al. (2009) · Cell · doi:10.1016/j.cell.2008.12.044 · Cited by 768 · see citing works

Bursting of Thalamic Neurons and States of Vigilance

Llinás, R. R., & Steriade, M. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00166.2006 · Cited by 682 · see citing works

Balancing cell adhesion and Wnt signaling, the key role of β-catenin

Brembeck, F. H., Rosário, M., & Birchmeier, W. (2005) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2005.12.007 · Cited by 668 · see citing works

Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

Kuwabara, T., Hsieh, J., Muotri, A., Yeo, G., Warashina, M., Lie, D. C., Moore, L., Nakashima, K., Asashima, M., & Gage, F. H. (2009) · Nature Neuroscience · doi:10.1038/nn.2360 · Cited by 648 · see citing works

The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells

Hirabayashi, Y., Itoh, Y., Tabata, H., Nakajima, K., Akiyama, T., Masuyama, N., & Gotoh, Y. (2004) · Development · doi:10.1242/dev.01165 · Cited by 600 · see citing works

Lack of the Burst Firing of Thalamocortical Relay Neurons and Resistance to Absence Seizures in Mice Lacking α1G T-Type Ca2+ Channels

Kim, D., Song, I., Keum, S., Lee, T., Jeong, M.-J., Kim, S.-S., McEnery, M. W., & Shin, H. (2001) · Neuron · doi:10.1016/s0896-6273(01)00343-9 · Cited by 523 · see citing works

β-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system

Zechner, D., Fujita, Y., Hülsken, J., Müller, T. H., Walther, I., Taketo, M. M., Crenshaw, E. B., Birchmeier, W., & Birchmeier, C. (2003) · Developmental Biology · doi:10.1016/s0012-1606(03)00123-4 · Cited by 484 · see citing works

AVID: A Global Alignment ProgramPreprint

Bray, N., Dubchak, I. L., & Pachter, L. S. (2002) · Genome Research · doi:10.1101/gr.789803 · Cited by 484 · see citing works

β-catenin–sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer

Hovanes, K., Li, T. W. H., Munguia, J. E., Truong, T., Milovanović, T., Marsh, J., Holcombe, R. F., & Waterman, M. L. (2001) · Nature Genetics · doi:10.1038/ng0501-53 · Cited by 458 · see citing works

β-catenin is critical for dendritic morphogenesis

Yu, X., & Malenka, R. C. (2003) · Nature Neuroscience · doi:10.1038/nn1132 · Cited by 454 · see citing works

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1

Galcerán, J., Miyashita-Lin, E. M., Devaney, E. J., Rubenstein, J. L. R., & Grosschedl, R. (2000) · Development · doi:10.1242/dev.127.3.469 · Cited by 399 · see citing works

Contrasting biophysical and pharmacological properties of T-type and R-type calcium channels

Randall, A. D., & Tsien, R. W. (1997) · Neuropharmacology · doi:10.1016/s0028-3908(97)00086-5 · Cited by 344 · see citing works

FusionDB: a database for in-depth analysis of prokaryotic gene fusion events

Suhre, K. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkh053 · Cited by 326 · see citing works

Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation

Chen, J., Park, C. S., & Tang, S.-J. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511920200 · Cited by 298 · see citing works

Cadherins and catenins at synapses: Roles in synaptogenesis and synaptic plasticity.

Arikkath, J., & Reichardt, L. F. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.07.001 · Cited by 289 · see citing works

Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis

Oosterwegel, M. A., van de Wetering, M., Timmerman, J. J., Kruisbeek, A. M., Destrée, O., Meijlink, F. C. P. W., & Clevers, H. C. (1993) · Development · doi:10.1242/dev.118.2.439 · Cited by 246 · see citing works

Wnt-3A/β-Catenin Signaling Induces Transcription from the LEF-1 Promoter

Filali, M. S., Cheng, N., Abbott, D., Leontiev, V. V., & Engelhardt, J. F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m107977200 · Cited by 241 · see citing works

The ups and downs of Wnt signaling in prevalent neurological disorders

Ferrari, G. V. D., & Moon, R. T. (2006) · Oncogene · doi:10.1038/sj.onc.1210064 · Cited by 221 · see citing works

T‐cell factors: turn‐ons and turn‐offs

Hurlstone, A. F. L., & Clevers, H. C. (2002) · The EMBO Journal · doi:10.1093/emboj/21.10.2303 · Cited by 208 · see citing works

Mutations in High-Voltage-Activated Calcium Channel Genes Stimulate Low-Voltage-Activated Currents in Mouse Thalamic Relay Neurons

Zhang, Y., Mori, M., Burgess, D. L., & Noebels, J. L. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06362.2002 · Cited by 198 · see citing works

Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization

Kaykas, A., Yang-Snyder, J., Héroux, M., Shah, K. V., Bouvier, M., & Moon, R. T. (2003) · Nature Cell Biology · doi:10.1038/ncb1081 · Cited by 174 · see citing works

TGFβ3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

Nawshad, A., & Hay, E. D. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200306024 · Cited by 159 · see citing works

Inactivation of CACNA1G, a T-type calcium channel gene, by aberrant methylation of its 5' CpG island in human tumors.

Toyota, M., Ho, C., Ohe-Toyota, M., Baylin, S. B., & Issa, J. J. (1999) · PubMed · Cited by 154 · see citing works

Genetic Enhancement of Thalamocortical Network Activity by Elevating α1G-Mediated Low-Voltage-Activated Calcium Current Induces Pure Absence Epilepsy

Ernst, W. L., Zhang, Y., Yoo, J. W., Ernst, S. J., & Noebels, J. L. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2081-08.2009 · Cited by 149 · see citing works

NMDA-Receptor Activation Induces Calpain-Mediated β-Catenin Cleavages for Triggering Gene Expression

Abe, K., & Takeichi, M. (2007) · Neuron · doi:10.1016/j.neuron.2007.01.016 · Cited by 144 · see citing works

Members of the Wnt, Fz, and Frp gene families expressed in postnatal mouse cerebral cortex

Shimogori, T., VanSant, J., Paik, E. K., & Grove, E. A. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20135 · Cited by 137 · see citing works

β-Catenin Overexpression in the Mouse Brain Phenocopies Lithium-Sensitive Behaviors

Gould, T. D., Einat, H., O’Donnell, K. C., Picchini, A. M., Schloesser, R. J., & Manji, H. K. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301338 · Cited by 137 · see citing works

T-type calcium channels in differentiation and proliferation

Lory, P., Bidaud, I., & Chemin, J. (2006) · Cell Calcium · doi:10.1016/j.ceca.2006.04.017 · Cited by 134 · see citing works

A Unique DNA Binding Domain Converts T-Cell Factors into Strong Wnt Effectors

Atcha, F. A., Syed, A., Wu, B., Hoverter, N. P., Yokoyama, N. N., Ting, J.-H. T., Munguia, J. E., Mangalam, H. J., Marsh, J., & Waterman, M. L. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.02132-06 · Cited by 132 · see citing works

Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways

Sancho, R. M., Law, B. M. H., & Harvey, K. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp337 · Cited by 125 · see citing works

Novel TCF‐binding sites specify transcriptional repression by Wnt signalling

Blauwkamp, T. A., Chang, M. V., & Cadigan, K. M. (2008) · The EMBO Journal · doi:10.1038/emboj.2008.80 · Cited by 121 · see citing works

A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis

Petropoulos, K., Arseni, N., Schessl, C., Stadler, C., Rawat, V. P. S., Deshpande, A. J., Heilmeier, B., Hiddemann, W., Quintanilla‐Martínez, L., Bohlander, S. K., et al. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20071875 · Cited by 120 · see citing works

Conditional Knock-Out of β-Cateninin Postnatal-Born Dentate Gyrus Granule Neurons Results in Dendritic Malformation

Gao, X., Arlotta, P., Macklis, J. D., & Chen, J. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3206-07.2007 · Cited by 108 · see citing works

Coordinated Changes in Dendritic Arborization and Synaptic Strength during Neural Circuit Development

Peng, Y., He, S., Marie, H., Zeng, S.-Y., Ma, J., Tan, Z.-J., Lee, S. Y., Malenka, R. C., & Yu, X. (2009) · Neuron · doi:10.1016/j.neuron.2008.11.015 · Cited by 107 · see citing works

Wnt Activation and Alternative Promoter Repression of LEF1 in Colon Cancer

Li, T. W. H., Ting, J.-H. T., Yokoyama, N. N., Bernstein, A., van de Wetering, M., & Waterman, M. L. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00105-06 · Cited by 107 · see citing works

Chromatin-specific regulation of LEF-1–β-catenin transcription activation and inhibition in vitro

Tutter, A. V., Fryer, C. J., & Jones, K. A. (2001) · Genes & Development · doi:10.1101/gad.946501 · Cited by 107 · see citing works

The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing

Hovanes, K., Li, T. W. H., & Waterman, M. L. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.9.1994 · Cited by 101 · see citing works

Parkin protects dopaminergic neurons from excessive Wnt/β-catenin signaling

Rawal, N., Corti, O., Sacchetti, P., Ardila-Osorio, H., Sehat, B., Brice, A., & Arenas, E. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.07.014 · Cited by 95 · see citing works

Expression of regulatory genes during differentiation of thalamic nuclei in mouse and monkey

Jones, E. G., & Rubenstein, J. L. R. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20234 · Cited by 88 · see citing works

Generation and behavioral characterization of β-catenin forebrain-specific conditional knock-out mice

Gould, T. D., O’Donnell, K. C., Picchini, A. M., Dow, E. R., Chen, G., & Manji, H. K. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.12.028 · Cited by 75 · see citing works

Activation of Wingless Targets Requires Bipartite Recognition of DNA by TCF

Chang, M. V., Chang, J. L., Gangopadhyay, A., Shearer, A. M., & Cadigan, K. M. (2008) · Current Biology · doi:10.1016/j.cub.2008.10.047 · Cited by 67 · see citing works

Developmental Expression of Wnt Signaling Factors in Mouse Brain

Coyle-Rink, J., Valle, L. D., Sweet, T., Khalili, K., & Amini, S. (2002) · Cancer Biology & Therapy · doi:10.4161/cbt.313 · Cited by 67 · see citing works

Synaptic Cross-talk between N-Methyl-d-aspartate Receptors and LAPSER1-β-Catenin at Excitatory Synapses

Schmeißer, M. J., Grabrucker, A. M., Bockmann, J., & Boeckers, T. M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.020628 · Cited by 53 · see citing works

Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex

Ivaniutsin, U., Chen, Y., Mason, J. O., Price, D. J., & Pratt, T. (2009) · Neural Development · doi:10.1186/1749-8104-4-3 · Cited by 47 · see citing works

Recovery from Inactivation of T-Type Ca2+Channels in Rat Thalamic Neurons

Kuo, C., & Yang, S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-06-01884.2001 · Cited by 35 · see citing works

Genomic response to Wnt signalling is highly context-dependent — Evidence from DNA microarray and chromatin immunoprecipitation screens of Wnt/TCF targets

Railo, A., Pajunen, A., Itäranta, P., Naillat, F., Vuoristo, J. T., Kilpeläinen, P., & Vainio, S. J. (2009) · Experimental Cell Research · doi:10.1016/j.yexcr.2009.06.021 · Cited by 30 · see citing works

Regulation of α1G T‐type calcium channel gene (CACNA1G) expression during neuronal differentiation

Bertolesi, G. E., Jollimore, C. A. B., Shi, C., Elbaum, L., Denovan‐Wright, E. M., Barnes, S., & Kelly, M. E. M. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02618.x · Cited by 30 · see citing works

Expression of the diabetes‐associated gene TCF7L2 in adult mouse brain

Lee, S., Lee, C. E., Elias, C. F., & Elmquist, J. K. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.22199 · Cited by 22 · see citing works

Nuclear localization of β-catenin in adult mouse thalamus correlates with low levels of GSK-3β

Lucas, J. J., Hernández, F., & Ávila, J. (1999) · Neuroreport · doi:10.1097/00001756-199909090-00002 · Cited by 11 · see citing works

Single-cell profiling of the developing mouse brain and spinal cord with split-pool barcoding

Rosenberg, A. B., Roco, C. M., Muscat, R. A., Kuchina, A., Sample, P., Yao, Z., Graybuck, L. T., Peeler, D. J., Mukherjee, S., Chen, W., et al. (2018) · Science · doi:10.1126/science.aam8999 · Cited by 1,422 · see citing works

WNT signaling underlies the pathogenesis of neuropathic pain in rodents

Zhang, Y., Huang, Z., Liu, S., Liu, Y.-P., Song, A. A., & Song, X. (2013) · Journal of Clinical Investigation · doi:10.1172/jci65364 · Cited by 214 · see citing works

Wnt Signaling and the Control of Human Stem Cell Fate

Camp, J. K. V., Beckers, S., Zegers, D., & Hul, W. V. (2013) · Stem Cell Reviews and Reports · doi:10.1007/s12015-013-9486-8 · Cited by 198 · see citing works

Secreted Frizzled-Related Protein 4 Reduces Insulin Secretion and Is Overexpressed in Type 2 Diabetes

Mahdi, T., Hänzelmann, S., Salehi, A. A., Muhammed, S. J., Reinbothe, T. M., Tang, Y., Axelsson, A. S., Zhou, Y., Jing, X., Almgren, P., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.10.009 · Cited by 194 · see citing works

Wnt Signaling: Role in Alzheimer Disease and Schizophrenia

Inestrosa, N. C., Montecinos-Oliva, C., & Fuenzalida, M. (2012) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-012-9417-5 · Cited by 186 · see citing works

The importance of Wnt signalling for neurodegeneration in Parkinson's disease

Berwick, D. C., & Harvey, K. (2012) · Biochemical Society Transactions · doi:10.1042/bst20120122 · Cited by 131 · see citing works

The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor

Zuccarini, M., Giuliani, P., Ziberi, S., Carluccio, M., Iorio, P. D., Caciagli, F., & Ciccarelli, R. (2018) · Genes · doi:10.3390/genes9020105 · Cited by 120 · see citing works

LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6

Berwick, D. C., & Harvey, K. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds342 · Cited by 105 · see citing works

Cognitive flexibility and long-term depression (LTD) are impaired following β-catenin stabilization in vivo

Mills, F., Bartlett, T. E., Dissing-Olesen, L., Wisniewska, M. B., Kuznicki, J., Macvicar, B. A., Wang, Y. T., & Bamji, S. X. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1404670111 · Cited by 82 · see citing works

Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways

Rolfe, R. A., Nowlan, N. C., Kenny, E. M., Cormican, P., Morris, D. W., Prendergast, P. J., Kelly, D. J., & Murphy, P. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-48 · Cited by 85 · see citing works

Physiological Role of β-Catenin/TCF Signaling in Neurons of the Adult Brain

Wisniewska, M. B. (2013) · Neurochemical Research · doi:10.1007/s11064-013-0980-9 · Cited by 83 · see citing works

Targeting the Wnt/β-catenin pathway in neurodegenerative diseases: recent approaches and current challenges

Serafino, A., Giovannini, D., Rossi, S., & Cozzolino, M. (2020) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2020.1746266 · Cited by 78 · see citing works

The regulation and deregulation of Wnt signaling by PARK genes in health and disease

Berwick, D. C., & Harvey, K. (2013) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjt037 · Cited by 75 · see citing works

Molecular anatomy of the thalamic complex and the underlying transcription factors

Nagalski, A., Puelles, L., Dąbrowski, M., Węgierski, T., Kuźnicki, J., & Wisniewska, M. B. (2015) · Brain Structure and Function · doi:10.1007/s00429-015-1052-5 · Cited by 64 · see citing works

Wnt and lithium: a common destiny in the therapy of nervous system pathologies?

Meffre, D., Grenier, J., Bernard, S., Courtin, F., Dudev, T., Shackleford, G., Jafarian-Tehrani, M., & Massaad, C. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1378-1 · Cited by 61 · see citing works

TCF7L2 regulates postmitotic differentiation programs and excitability patterns in the thalamus

Lipiec, M. A., Koziński, K., Zajkowski, T., Bem, J., Urban‐Ciećko, J., Dąbrowski, M., Chakraborty, C., Szewczyk, Ł. M., Toval, Á., Ferrán, J. L., et al. (2020) · Development · doi:10.1242/dev.190181 · Cited by 50 · see citing works

Synaptic Plasticity at Intrathalamic Connections via CaV3.3 T-type Ca2+Channels and GluN2B-Containing NMDA Receptors

Astori, S., & Lüthi, A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3185-12.2013 · Cited by 48 · see citing works

The Tale of the Three Brothers – Shh, Wnt, and Fgf during Development of the Thalamus

Hagemann, A. I. H., & Scholpp, S. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00076 · Cited by 47 · see citing works

Compensatory T-type Ca2+ channel activity alters D2-autoreceptor responses of Substantia nigra dopamine neurons from Cav1.3 L-type Ca2+ channel KO mice

Pötschke, C., Dragicevic, E., Duda, J., Benkert, J., Dougalis, A., Zio, R. D., Snutch, T. P., Striessnig, J., & Liss, B. (2015) · Scientific Reports · doi:10.1038/srep13688 · Cited by 46 · see citing works

Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders

Lee, S., McAfee, J. C., Lee, J., Gomez, A., Ledford, A. T., Clarke, D., Min, H., Gerstein, M., Boyle, A. P., Sullivan, P. F., et al. (2025) · Cell · doi:10.1016/j.cell.2024.12.022 · Cited by 44 · see citing works

Novel β-catenin target genes identified in thalamic neurons encode modulators of neuronal excitability

Wisniewska, M. B., Nagalski, A., Dąbrowski, M., Misztal, K., & Kuźnicki, J. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-635 · Cited by 42 · see citing works

High-Throughput Data Reveals Novel Circular RNAs via Competitive Endogenous RNA Networks Associated with Human Intracranial Aneurysms

Huang, Q., Huang, Q., Sun, Y., & Wu, S. (2019) · Medical Science Monitor · doi:10.12659/msm.917081 · Cited by 39 · see citing works

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain

Nagalski, A., Irimia, M., Szewczyk, Ł. M., Ferrán, J. L., Misztal, K., Kuźnicki, J., & Wisniewska, M. B. (2012) · Brain Structure and Function · doi:10.1007/s00429-012-0474-6 · Cited by 36 · see citing works

Serine 133 phosphorylation is not required for hippocampal CREB-mediated transcription and behaviorPreprint

Briand, L. A., Lee, B. G., Lay, J. E. L., Kaestner, K. H., & Blendy, J. A. (2015) · Learning & Memory · doi:10.1101/lm.037044.114 · Cited by 33 · see citing works

A signaling loop of REST, TSC2 and β-catenin governs proliferation and function of PC12 neural cells

Tomasoni, R., Negrini, S., Fiordaliso, S., Klajn, A., Tkatch, T., Mondino, A., Meldolesi, J., & D’Alessandro, R. (2011) · Journal of Cell Science · doi:10.1242/jcs.087551 · Cited by 31 · see citing works

WNT Signaling Is a Key Player in Alzheimer’s Disease

Inestrosa, N. C., Tapia‐Rojas, C., Cerpa, W. F., Cisternas, P., & Zolezzi, J. M. (2021) · Handbook of experimental pharmacology · doi:10.1007/164_2021_532 · Cited by 28 · see citing works

TCF4 Mediates the Maintenance of Neuropathic Pain Through Wnt/β-Catenin Signaling Following Peripheral Nerve Injury in Rats

Xu, Z., Chen, Y., Jiang, Y., Yin, D., Liu, C., Chen, X., & Zhang, D. (2015) · Journal of Molecular Neuroscience · doi:10.1007/s12031-015-0565-y · Cited by 28 · see citing works

The transcriptional landscape of Alzheimer’s disease and its association with Wnt signaling pathway

Martínez, M., & Inestrosa, N. C. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.06.029 · Cited by 25 · see citing works

Relationship between serum secreted frizzled-related protein 4 levels and the first-phase of glucose-stimulated insulin secretion in individuals with different glucose tolerance

Liu, F., Qu, H., Li, Y., Tang, Q. J., Yang, Z., Wang, H., & Deng, H. (2015) · Endocrine Journal · doi:10.1507/endocrj.ej15-0212 · Cited by 24 · see citing works

Cav3 T‐type calcium channels

Senatore, A., Zhorov, B. S., & Spafford, J. (2012) · Wiley Interdisciplinary Reviews Membrane Transport and Signalling · doi:10.1002/wmts.41 · Cited by 31 · see citing works

A novel flavonoid derivative of icariside II improves erectile dysfunction in a rat model of cavernous nerve injury

Gu, S.-J., Li, M., Yuan, Y., Xin, Z., & Guan, R. (2021) · Andrology · doi:10.1111/andr.13065 · Cited by 24 · see citing works

Computer Aided Screening of Secreted Frizzled-Related Protein 4 (SFRP4): A Potential Control for Diabetes Mellitus

Bukhari, S. A., Shamshari, W. A., Rahman, M. U., Zia‐Ul‐Haq, M., & Jaafar, H. Z. E. (2014) · Molecules · doi:10.3390/molecules190710129 · Cited by 22 · see citing works

WNT Protein-independent Constitutive Nuclear Localization of β-Catenin Protein and Its Low Degradation Rate in Thalamic Neurons

Misztal, K., Wisniewska, M. B., Ambrozkiewicz, M. C., Nagalski, A., & Kuźnicki, J. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.229666 · Cited by 19 · see citing works

Loss of β-catenin via activated GSK3β causes diabetic retinal neurodegeneration by instigating a vicious cycle of oxidative stress-driven mitochondrial impairment

Shu, X., Zhu, H., Huang, X., Yang, Y., Wang, D., Zhang, Y., Zhang, W., & Ying, Y. (2020) · Aging · doi:10.18632/aging.103446 · Cited by 19 · see citing works

TCF7L2 mediates the cellular and behavioral response to chronic lithium treatment in animal models

Misztal, K., Brożko, N., Nagalski, A., Szewczyk, Ł. M., Krolak, M., Brzozowska, K., Kuźnicki, J., & Wisniewska, M. B. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.10.027 · Cited by 18 · see citing works

Identification of Zebrafish Calcium Toolkit Genes and Their Expression in the Brain

Wasilewska, I., Gupta, R. K., Palchevska, O., & Kuźnicki, J. (2019) · Genes · doi:10.3390/genes10030230 · Cited by 17 · see citing works

Effect of treadmill exercise on pain-related Wnt/β-catenin signaling pathway in dorsal root ganglion neurons at the early phase regeneration of the injured sciatic nerve

Cho, Y.-H., Kim, J.-E., & Seo, T.-B. (2021) · Journal of Exercise Rehabilitation · doi:10.12965/jer.2142136.068 · Cited by 16 · see citing works

Axin: An emerging key scaffold at the synapse

Chen, Y., Fu, A. K. Y., & Ip, N. Y. (2013) · IUBMB Life · doi:10.1002/iub.1184 · Cited by 16 · see citing works

Metabolic pathways in the periphery and brain: Contribution to mental disorders?

Nagalski, A., Koziński, K., & Wisniewska, M. B. (2016) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2016.09.012 · Cited by 14 · see citing works

Transcription Factor Sp1 Regulates T‐Type Ca2+ Channel CaV3.1 Gene Expression

González‐Ramírez, R., Martínez‐Hernández, E., Sandoval, A., & Felix, R. (2013) · Journal of Cellular Physiology · doi:10.1002/jcp.24432 · Cited by 12 · see citing works

Association between immunity and different clinical symptoms in patients with polycystic ovary syndrome

Xiao, H., Yin, T.-L., Diao, L., Zhang, Y., & Huang, C. (2023) · American Journal of Reproductive Immunology · doi:10.1111/aji.13780 · Cited by 11 · see citing works

The expression and activity of β-catenin in the thalamus and its projections to the cerebral cortex in the mouse embryo

Pratt, T., Davey, J. W., Nowakowski, T. J., Raasumaa, C., Rawlik, K., McBride, D., Clinton, M., Mason, J. O., & Price, D. J. (2012) · BMC Neuroscience · doi:10.1186/1471-2202-13-20 · Cited by 11 · see citing works

NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice

Guo, F., Seldin, M. M., Péterfy, M., Charugundla, S., Zhou, Z., Lee, S. D., Mouton, A., Rajbhandari, P., Zhang, W., Pellegrini, M. A., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-95720-1 · Cited by 10 · see citing works

Expression of the Longest RGS4 Splice Variant in the Prefrontal Cortex Is Associated with Single Nucleotide Polymorphisms in Schizophrenia Patients

Ding, L., Stýblo, M., Drobná, Z., & Hegde, A. N. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00026 · Cited by 10 · see citing works

Transcriptional regulation of α1H T-type calcium channel under hypoxia

Sellak, H., Zhou, C., Liu, B., Chen, H., Lincoln, T., & Wu, S. (2014) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00210.2014 · Cited by 10 · see citing works

Transcriptional Regulation of Mouse PXR Gene: An Interplay of Transregulatory Factors

Kumari, S., Mukhopadhyay, G., & Tyagi, R. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044126 · Cited by 9 · see citing works

Treadmill running on neuropathic pain: via modulation of neuroinflammation

He, W., Hou, S.-L., Wang, K.-B., Xu, N., Li, K., Xiong, T., & Luo, J. (2024) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2024.1345864 · Cited by 7 · see citing works

Screening of Potential Genes and Transcription Factors of Postoperative Cognitive Dysfunction via Bioinformatics Methods

Wang, Y., Huang, A., Gan, L., Bao, Y., Zhu, W., Hu, Y., Ma, L., Wei, S., & Lan, Y. (2018) · Medical Science Monitor · doi:10.12659/msm.907445 · Cited by 7 · see citing works

Evaluation of the effects of the T-type calcium channel enhancer SAK3 in a rat model of TAF1 deficiency

Chinnasamy, D., Janakiraman, U., Moutal, A., Fukunaga, K., Khanna, R., & Nelson, M. A. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2020.105224 · Cited by 7 · see citing works

Dynamic Expression Profiles of β-Catenin during Murine Cardiac Valve Development

Guo, L., Glover, J. S., Risner, A., Wang, C. E., Fulmer, D. B., Moore, K. S., Gensemer, C., Rumph, M. K., Moore, R. A., Beck, T. C., et al. (2020) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd7030031 · Cited by 6 · see citing works

spARC recovers human glioma spatial signaling networks with graph filteringPreprint

Kuchroo, M. R., Miyagishima, D. F., Steach, H. R., Godavarthi, A., Takeo, Y., Duy, P. Q., Barak, T., Erson-Omay, Z., Youlten, S. E., Mishra-Gorur, K., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.08.24.505139 · Cited by 6 · see citing works

Finding a Needle in a Genomic Haystack

Bhambhani, C., & Cadigan, K. M. (2014) · doi:10.1002/9781118444122.ch5 · Cited by 5 · see citing works

Enhanced yield and subtype identity of hPSC-derived midbrain dopamine neuron by modulation of WNT and FGF18 signalingPreprint

Kim, T. W., Piao, J., Bocchi, V. D., Koo, S. Y., Choi, S. J., Chaudhry, F. F., Yang, D., Cho, H., Hergenreder, E., Perera, L. R., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.06.631400 · Cited by 5 · see citing works

CI-994 is a dual modulator of class I HDACs and Wnt/β-catenin signaling for the treatment of Alzheimer's disease

Lu, W., Kawatani, K., Ren, Y., Nambara, T., Jia, L., Jeevaratnam, S., Lee, E., Martinez, P. R., Izhar, T., Wang, N., et al. (2026) · Alzheimer's Research & Therapy · doi:10.1186/s13195-026-01982-0 · Cited by 4 · see citing works

Elevated striatal dopamine attenuates nigrothalamic inputs and impairs transthalamic cortico-cortical communication in schizophrenia: A hypothesis

Vukadinovic, Z. (2014) · Medical Hypotheses · doi:10.1016/j.mehy.2014.11.014 · Cited by 3 · see citing works

A Study to Evaluate the Role of Secreted Frizzled-Related Protein 4 (SFRP4) as a Potential Novel Biomarker of Type 2 Diabetes Mellitus

Shrewastwa, M. K., Acharya, V., Kumar, B. S., & Ray, S. (2023) · Medical Journal of Dr D Y Patil Vidyapeeth · doi:10.4103/mjdrdypu.mjdrdypu_987_22 · Cited by 3 · see citing works

Tissue-Specific Chromatin Accessibility Regions and Transcription Factor Binding Sites in Pig Brain and Endocrine Tissues

Ponsuksili, S., Hadlich, F., Trakooljul, N., Li, S., Reyer, H., Oster, M., & Wimmers, K. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05128-5 · Cited by 2 · see citing works

Presynaptic P/Q calcium channel deficit promotes postsynaptic excitability remodeling and neurogenesis in developing thalamic circuitry

Thompson, S. J., Miao, Q., Sonig, A., & Noebels, J. L. (2026) · Neuron · doi:10.1016/j.neuron.2026.03.015 · Cited by 2 · see citing works

Exercise alleviates symptoms of CNS lupus

Jacob, A., Peralta, L. N., Pegues, D., Okamura, K., Chang, A., McSkimming, D. I., & Alexander, J. J. (2021) · Brain Research · doi:10.1016/j.brainres.2021.147478 · Cited by 2 · see citing works

The VAX2-SERPINE1 axis modulates colorectal cancer cell proliferation and apoptosis through WNT/beta-catenin signaling

Zhang, J., Liu, G., Peng, S., Chen, Y., Xie, Y., Lei, Y., Wu, J., Huang, X., Wei, X., Hong, L., et al. (2026) · Translational Oncology · doi:10.1016/j.tranon.2026.102703 · Cited by 1 · see citing works

Harnessing the master transcriptional repressor REST to reciprocally regulate neurogenesis

Nesti, E. (2015) · Neurogenesis · doi:10.1080/23262133.2015.1055419 · Cited by 1 · see citing works

Mechanisms of defective insulin secretion in type 2 diabetes

Mahdi, T. (2013) · Lund University Publications (Lund University)

Optimization of ChIP protocol for investigation of canonical Wnt target genes expression in new born heart

Piven, O. O. (2018) · Faktori eksperimental noi evolucii organizmiv · doi:10.7124/feeo.v22.943

Wnt/β-Catenin Signaling Causes Sinoatrial Node Dysfunction by Inhibition of T-type Calcium CurrentPreprint

Florczak, K., Lu, A., Wang, J., Gu, R., Xia, Y., Kim, K.-H., Stewart, D. J., Davis, D. R., & Liang, W. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4640265

Lef1/betta-catenin reegulates Cav3.1 T-type calcium channel gene (CACNAIG) in the thalamus

Wisniewska, M. B., Michowski, W., Leśniak, W., Misztal, K., Dąbrowski, M., & Kuźnicki, J. (2009) · Acta Neurobiologiae Experimentalis

Transcription Factor Sp1 Regulates T‐Type Ca2+ Channel CaV3.1 Gene Expression

González‐Ramírez, R., Martínez‐Hernández, E., Sandoval, A., & Felix, R. (2013) · Journal of Cellular Physiology · doi:10.1002/jcp.24432 · Cited by 12 · see citing works

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain

Nagalski, A., Irimia, M., Szewczyk, Ł. M., Ferrán, J. L., Misztal, K., Kuźnicki, J., & Wisniewska, M. B. (2012) · Brain Structure and Function · doi:10.1007/s00429-012-0474-6 · Cited by 36 · see citing works

The C Terminus of the L-Type Voltage-Gated Calcium Channel CaV1.2 Encodes a Transcription Factor

Gomez‐Ospina, N., Tsuruta, F., Chang, O. L. B., Hu, L. S., & Dolmetsch, R. E. (2006) · Cell · doi:10.1016/j.cell.2006.10.017 · Cited by 392 · see citing works

Nuclear Beta-catenin is constitutively present in postmitotic thalamic neurons due to reduced activity of Beta-catenin degradation complex

Misztal, K., Wisniewska, M. B., Ambrozkiewicz, M. C., & Kuźnicki, J. (2011) · Acta Neurobiologiae Experimentalis