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Cited by 221Visual perception and processing mechanismsMotor Control and AdaptationVestibular and auditory disorders

Representation of Eye Movements and Stimulus Motion in Topographically Organized Areas of Human Posterior Parietal Cortex

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Konen, Christina S., Kastner, Sabine·2008·The Journal of Neuroscience
DOI 10.1523/jneurosci.1930-08.2008PMC PMC2685070
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Abstract

Recent imaging studies have shown that the human posterior parietal cortex (PPC) contains four topographically organized areas along the intraparietal sulcus (IPS1–IPS4). Using a memory-guided saccade paradigm, we confirmed the locations and retinotopic organization of IPS1–IPS4 and identified two additional areas, IPS5 and superior parietal lobule 1 (SPL1). IPS5 is located at the intersection of the intraparietal and postcentral sulcus; SPL1 branches off the IPS and extends into the superior parietal lobule. Both areas, as well as IPS1–IPS4, each contain a representation of the contralateral visual hemifield. We then probed core functions of the dorsal pathway in these areas, that is, the representation of eye movements and visual motion, to compare the functional characteristics of human PPC to physiologically and anatomically defined areas in monkey PPC. First, as in monkey PPC, a gradient representation of eye movements was found along the IPS with decreasing responses for saccades and increasing responses for smooth pursuit eye movements from posterior/medial to anterior/lateral. The greatest preference for saccades was found in SPL1 and for smooth pursuit in IPS5. Second, and again similar to monkey PPC, all topographically organized PPC areas responded to different types of motion including planar, circular, and radial optic flow, as assessed using adaptation paradigms. Areas in posterior IPS preferred radial optic flow over planar motion, whereas areas in anterior PPC did not show preference for a particular motion type. Together, our results indicate strikingly similar characteristics in the general functional organization of human and monkey PPC, but also reveal some notable differences.

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  • Multiple fMRI studies suggest that other functions associated with VIP in non-human primates, such as optic flow movement, or ego-motion and vestibular conscious perception, involve different regions in IPS and surrounding parietal cortex.

    “multiple fMRI studies suggest that other functions associated with VIP in non-human primates, such as optic flow movement (Konen and Kastner 2008; Sulpizio et al. 2020), or ego-motion and vestibular conscious perception (Schindler and Bartels 2018; Aedo-Jury et al. 2020), involve different regions in the IPS and the surrounding parietal cortex.”

    From Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition (2024) · cites this paper as Konen and Kastner 2008

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Authors
Konen, C. S., & Kastner, S.
Affiliations
Princeton University (US)
Venue
The Journal of Neuroscience
Publisher
Society for Neuroscience
Published
2008-08-13
Volume
28
Issue
33
Pages
8361-8375
ISSN
  • 0270-6474 (ISSN-L)
  • 1529-2401
DOI
10.1523/jneurosci.1930-08.2008
PMC
PMC2685070
OpenAlex
W2044504605
Cited by
221
References
8
Citations by year
2026: 6 · 2025: 8 · 2024: 17 · 2023: 17 · 2022: 6 · 2021: 6 · 2020: 11 · 2019: 9 · 2018: 17 · 2017: 10 · 2016: 12 · 2015: 17 · 2014: 11 · 2013: 20 · 2012: 13
FWCI
7.06
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Deutscher Akademischer Austauschdienst
  • National Institutes of Health (2r01ey017699-14)
  • National Institute of Mental Health (2R01MH64043, P50MH062196, 2P50 MH-62196, R01MH064043)
  • National Eye Institute (R01EY-017699, 1R01 EY017699)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
  • Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
Keywords
posterior parietal cortex, intraparietal sulcus, superior parietal lobule, retinotopic organization, saccades, smooth pursuit eye movements, visual motion processing, optical flow, dorsal visual pathway, human-monkey comparison, adaptation paradigm
MeSH terms
Adult, Brain Mapping, Eye Movements, Female, Humans, Male, Motion Perception, Parietal Lobe, Photic Stimulation, Psychomotor Performance

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