The DOI matches its Crossref record; 56 of the 58 references it cites were found in a registry or an index.
Distinct Regions of Prefrontal Cortex Mediate Resistance and Vulnerability to Depression
Open accessAbstract
The neuroanatomical correlates of depression remain unclear. Functional imaging data have associated depression with abnormal patterns of activity in prefrontal cortex (PFC), including the ventromedial (vmPFC) and dorsolateral (dlPFC) sectors. If vmPFC and dlPFC are critical neural substrates for the pathogenesis of depression, then damage to either area should affect the expression of depressive symptoms. Using patients with brain lesions we show that, relative to nonfrontal lesions, bilateral vmPFC lesions are associated with markedly low levels of depression, whereas bilateral dorsal PFC lesions (involving dorsomedial and dorsolateral areas in both hemispheres) are associated with substantially higher levels of depression. These findings demonstrate that vmPFC and dorsal PFC are critically and causally involved in depression, although with very different roles: vmPFC damage confers resistance to depression, whereas dorsal PFC damage confers vulnerability.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“damage to VMPFC is associated with low levels of depression, and damage to DLPFC is associated with high levels of depression 206.”
From Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications (2022) · cites this paper as [206]
In the citing paper
“damage to VMPFC is associated with low levels of depression, and damage to DLPFC is associated with high levels of depression 206.”
From Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications (2022) · cites this paper as [206]
In the citing paper
“By virtue of its well-established capacity for regulating mood, attention, memory, and action34, 54-56”
From Evolutionarily conserved prefrontal-amygdalar dysfunction in early-life anxiety (2014) · cites this paper as [56]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
Tzourio-Mazoyer, N., Landeau, B., Papathanassiou, D., Crivello, F., Etard, O., Delcroix, N., Mazoyer, B., & Joliot, M. (2002) · NeuroImage · doi:10.1006/nimg.2001.0978 · Cited by 16,319
Beck, A. T., Steer, R. A., & Brown, G. (2011) · PsycTESTS Dataset · doi:10.1037/t00742-000 · Cited by 7,535
Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications
Clark, L. A., & Watson, D. (1991) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.100.3.316 · Cited by 4,601
Deep Brain Stimulation for Treatment-Resistant Depression
Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059
Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space
Collins, D. L., Neelin, P., Peters, T. M., & Evans, A. C. (1994) · Journal of Computer Assisted Tomography · doi:10.1097/00004728-199403000-00005 · Cited by 3,431 · cited 1×
“The CT image of each brain was spatially normalized to a CT template brain image in MNI space (Collins et al., 1994).”
MethodRethinking feelings: an fMRI study of the cognitive regulation of emotion
Ochsner, K. N., Bunge, S. A., Gross, J. J., & Gabrieli, J. D. E. (2002) · Journal of Cognitive Neuroscience · doi:10.1162/089892902760807212 · Cited by 2,520
Mayberg, H. S., Liotti, M., Brannan, S. K., McGinnis, S., Mahurin, R. K., Jerabek, P. A., Silva, J. A., Tekell, J. L., Martin, C. C., Lancaster, J. L., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.675 · Cited by 2,416
Greicius, M. D., Flores, B. H., Menon, V., Glover, G. H., Solvason, H. B., Kenna, H., Reiss, A. L., & Schatzberg, A. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.020 · Cited by 2,214
Ochsner, K. N., Ray, R. D., Cooper, J. C., Robertson, E. R., Chopra, S., Gabrieli, J. D. E., & Gross, J. J. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.06.030 · Cited by 2,113
Research works printed but not linked: 2
- Damasio H Damasio AR (1989) Lesion analysis in neurospychology (Oxford UP, New York).
- First MB Spitzer RL Gibbon M Williams JBW (2002) Structured clinical interview for DSM-IV-TR axis I disorders, research version (Biometrics Research, New York State Psychiatric Institute, (SCID-I/P) New York) patient edition.
Cited by
Sorted by citations
Items 101–200 of 243
Carlson, J. M., DePetro, E., Maxwell, J. W., Harmon‐Jones, E., & Hajcak, G. (2015) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2015.06.005 · Cited by 27
Ahn, S. J., Kyeong, S.-H., Suh, S. H., Kim, J., Chung, T.-S., & Seok, J. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-1116-y · Cited by 26
Wu, X., Wang, L., Jiang, H., Fu, Y., Wang, T., Ma, Z., Wu, X., Wang, Y., Fan, F., Song, Y., et al. (2023) · NeuroImage Clinical · doi:10.1016/j.nicl.2023.103445 · Cited by 24
Muzik, O., & Diwadkar, V. A. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.08.015 · Cited by 25
The neural basis of conceptual–emotional integration and its role in major depressive disorder
Green, S., Lambon Ralph, M. A., Moll, J., Zakrzewski, J., Deakin, J. F. W., Grafman, J., & Zahn, R. (2013) · Social Neuroscience · doi:10.1080/17470919.2013.810171 · Cited by 24
Self-citationVolumetrics relate to the development of depression after traumatic brain injury
Maller, J. J., Thomson, R. H., Pannek, K., Bailey, N. W., Lewis, P., & Fitzgerald, P. B. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.047 · Cited by 25
SEEKING and depression in stroke patients: An exploratory study
Farinelli, M., Panksepp, J., Gestieri, L., Leo, M. R., Agati, R., Maffei, M., Leonardi, M., & Northoff, G. (2013) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2013.776009 · Cited by 25
Sacu, S., Wackerhagen, C., Erk, S., Romanczuk‐Seiferth, N., Schwarz, K., Schweiger, J. I., Tost, H., Meyer‐Lindenberg, A., Heinz, A., Razi, A., et al. (2022) · Psychological Medicine · doi:10.1017/s0033291722000824 · Cited by 24
Targeting the Neuronal Activity of Prefrontal Cortex: New Directions for the Therapy of Depression
Zhou, X., Bao, W.-D., Liu, D., & Zhu, L. (2019) · Current Neuropharmacology · doi:10.2174/1570159x17666191101124017 · Cited by 22
Song, Y., Huang, C., Zhong, Y., Wang, X., & Tao, G. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.924431 · Cited by 22
Cannabidiol Modulates Alterations in PFC microRNAs in a Rat Model of Depression
Bright, U., & Akirav, I. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032052 · Cited by 21
Frontoamygdalar Effective Connectivity in Youth Depression and Treatment Response
Kung, P., Davey, C. G., Harrison, B. J., Jamieson, A. J., Felmingham, K. L., & Steward, T. (2023) · Biological Psychiatry · doi:10.1016/j.biopsych.2023.06.009 · Cited by 24
Stieger, J., Pinheiro‐Chagas, P., Fang, Y., Li, J., Lusk, Z., Perry, C., Girn, M., Contreras, D., Chen, Q., Huguenard, J. R., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2316021121 · Cited by 20
Martin, D. M., Yeung, K., & Loo, C. K. A. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.05.072 · Cited by 20
Castagna, P. J., Roye, S., Calamia, M. R., Owens-French, J., Davis, T. E., & Greening, S. G. (2017) · Brain Imaging and Behavior · doi:10.1007/s11682-017-9772-1 · Cited by 21
Self-citationBailey, N. W., Hoy, K. E., Maller, J. J., Segrave, R. A., Thomson, R. H., Williams, N., Daskalakis, Z. J., & Fitzgerald, P. B. (2014) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2014.09.008 · Cited by 18
Canceri, J. M., Brown, R., Watson, S. R. D., & Browne, C. J. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00943 · Cited by 20
Struckmann, W., Persson, J., Weigl, W., Gingnell, M., & Bodén, R. (2020) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2020.1785007 · Cited by 19
Lu, Y., Jin, X., Feng, L.-W., Tang, C., Neo, H. L. M., & Ho, R. (2022) · World Journal of Clinical Cases · doi:10.12998/wjcc.v10.i34.12515 · Cited by 19
Tepfer, L. J., Alloy, L. B., & Smith, D. V. (2021) · Depression and Anxiety · doi:10.1002/da.23143 · Cited by 19
Neural systems underlying thought suppression in young women with, and at-risk, for depression.
Carew, C., Milne, A., Tatham, E. L., MacQueen, G., & Hall, G. B. C. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.09.016 · Cited by 22
Li, Y., Li, H.-P., Wu, M.-X., Wang, Q.-Y., & Zeng, X. (2022) · Clinical Neurophysiology · doi:10.1016/j.clinph.2022.07.369 · Cited by 19
Basavaraju, R., Feng, X., France, J., Huey, E. D., & Provenzano, F. A. (2020) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988720964258 · Cited by 18
Self-citationNeural Substrates of Poststroke Depression: Current Opinions and Methodology Trends
Pan, C., Li, G., Sun, W., Miao, J., Qiu, X., Lan, Y., Wang, Y., Wang, H., Zhu, Z., & Zhu, S. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.812410 · Cited by 20
Neuroanatomical correlates of individual differences in social anxiety in a non-clinical population
Tian, X. S., Hou, X., Wang, K., Wei, D., & Qiu, J. (2015) · Social Neuroscience · doi:10.1080/17470919.2015.1091037 · Cited by 18
Nihonmatsu-Kikuchi, N., Hayashi, Y., Yu, X., & Tatebayashi, Y. (2013) · Journal of Alzheimer s Disease · doi:10.3233/jad-130752 · Cited by 18
Kagan, J. (2010) · Emotion Review · doi:10.1177/1754073909353950 · Cited by 18
A Critical Review of Behavioral and Emotional Disinhibition
Huey, E. D. (2020) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000001134 · Cited by 19
Self-citationThe Complexity of Suicide: Review of Recent Neuroscientific Evidence
Ching, E. (2016) · Cited by 16
Wang, N., Shi, M., Wang, J., & Luo, F. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.09.021 · Cited by 16
A pilot study of the prevalence of psychiatric disorders in PLS and ALS
Huey, E. D., Koppel, J. L., Armstrong, N. M., Grafman, J. H., & Floeter, M. K. (2010) · Amyotrophic Lateral Sclerosis · doi:10.3109/17482960903544576 · Cited by 16
Self-citationDiminished appetitive startle modulation following targeted inhibition of prefrontal cortex
Hurlemann, R., Arndt, S. V., Schlaepfer, T. E., Reul, J., Maier, W., & Scheele, D. (2015) · Scientific Reports · doi:10.1038/srep08954 · Cited by 18
Affective Processing in Non-invasive Brain Stimulation Over Prefrontal Cortex
Liu, W., Leng, Y. S., Zou, X. H., Cheng, Z. Q., Yang, W., & Li, B. J. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00439 · Cited by 16
Jorge, R. E. (2015) · Handbook of clinical neurology · doi:10.1016/b978-0-444-63521-1.00038-8 · Cited by 19
Establishing a Causal Role for Medial Prefrontal Cortex in Reality Monitoring
Subramaniam, K., Kothare, H., Hinkley, L. B. N., Tarapore, P. E., & Nagarajan, S. S. (2020) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2020.00106 · Cited by 18
Papadaki, E. Z., Kavroulakis, E., Manolitsi, K., Makrakis, D., Papastefanakis, E., Tsagaraki, P., Papadopoulou, S., Zampetakis, A., Malliou, M., Vakis, A. F., et al. (2020) · Brain Imaging and Behavior · doi:10.1007/s11682-020-00343-1 · Cited by 15
Ishida, T., Dierks, T., Strik, W. K., & Morishima, Y. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00836 · Cited by 18
Wang, T., Liu, X., Wu, X., Fan, Y., Lv, Y., & Chen, B. (2023) · Clinical Neurophysiology · doi:10.1016/j.clinph.2023.11.019 · Cited by 15
Nogueira, M. H., Pimentel‐Silva, L. R., Moreira, J. C. V., de Rezende, T. J. R., Zanao, T. A., de Campos, B. M., Yasuda, C. L., & Cendes, F. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2019.01398 · Cited by 15
Osborn, A. J., Mathias, J. L., Fairweather‐Schmidt, A. K., & Anstey, K. J. (2017) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0000000000000311 · Cited by 15
Tu, C., Chen, C., Yang, C.-C., Gałecki, P., & Su, K. (2020) · Journal of Personalized Medicine · doi:10.3390/jpm10040283 · Cited by 15
Lee, K., Kwon, J., Chun, M., Choi, J., Lee, S., & Im, C. (2024) · Depression and Anxiety · doi:10.1155/2024/4459867 · Cited by 15
Healthy individuals vs patients with bipolar or unipolar depression in gray matter volume
Zhang, Y.-N., Li, H., Shen, Z., Xu, C. S., Huang, Y., & Wu, R. (2021) · World Journal of Clinical Cases · doi:10.12998/wjcc.v9.i6.1304 · Cited by 15
Neural signal variability relates to maladaptive rumination in depression
Philippi, C. L., Leutzinger, K., Pessin, S., Cassani, A., Mikel, O., Walsh, E. C., Hoks, R. M., Birn, R. M., & Abercrombie, H. C. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.10.070 · Cited by 14
Opposing effects of perceptual versus working memory load on emotional distraction
Tavares, T., Logie, K., & Mitchell, D. (2016) · Experimental Brain Research · doi:10.1007/s00221-016-4697-2 · Cited by 14
A depression network caused by brain tumours
Li, Y., Jin, Y., Wu, D., & Zhang, L. (2022) · Brain Structure and Function · doi:10.1007/s00429-022-02573-z · Cited by 15
Aggression, DRD1 polymorphism, and lesion location in penetrating traumatic brain injury
Pardini, M., Krüeger, F., Hodgkinson, C. A., Raymont, V., Strenziok, M., Amore, M., Wassermann, E. M., Goldman, D. A., & Grafman, J. H. (2014) · CNS Spectrums · doi:10.1017/s1092852914000108 · Cited by 14
Self-citationCheng, C., Li, C., Jeng, J., Chang, W.-H., Lin, W., Chen, M., Bai, Y., Tsai, S., & Su, T. (2022) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-022-01523-4 · Cited by 16
Neural correlates of improvements in personality and behavior following a neurological event
King, M. L., Manzel, K. W., Bruss, J., & Tranel, D. (2017) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2017.11.023 · Cited by 14
Self-citationPrefrontal asymmetry in depression? The long-term effect of unilateral brain lesions
Koenigs, M. R., & Grafman, J. H. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.04.063 · Cited by 14
Self-citationCognitive and Behavioral Outcomes from Traumatic Brain Injury
Griffen, J., & Hanks, R. (2014) · Handbook on the Neuropsychology of Traumatic Brain Injury · doi:10.1007/978-1-4939-0784-7_2 · Cited by 19
Iravani, B., Kaboodvand, N., Stieger, J., Liang, E. Y., Lusk, Z., Fransson, P., Deutsch, G. K., Gotlib, I. H., & Parvizi, J. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1634-23.2024 · Cited by 12
Diffusion tensor imaging correlates of depressive symptoms in Parkinson disease
Uhr, L., Tsolaki, E. C., & Pouratian, N. (2022) · The Journal of Comparative Neurology · doi:10.1002/cne.25310 · Cited by 12
Lapate, R. C., Heckner, M. K., Phan, A., Tambini, A., & D’Esposito, M. (2024) · Nature Communications · doi:10.1038/s41467-024-48015-8 · Cited by 11
Emotion regulation in emerging adults with major depressive disorder and frequent cannabis use
Nichols, E. S., Penner, J., Ford, K. A., Wammes, M., Neufeld, R. W. J., Mitchell, D. G. V., Greening, S. G., Théberge, J., Williamson, P., & Osuch, E. A. (2021) · NeuroImage Clinical · doi:10.1016/j.nicl.2021.102575 · Cited by 12
Wang, M., Zhang, K., Zhang, J., Dong, G., Zhang, H., & Du, X. (2015) · PLoS ONE · doi:10.1371/journal.pone.0142957 · Cited by 11
The medial prefrontal cortex: a potential link between self-deception and affect
Duran, K. A., O’Halloran, H., Soder, H. E., Yasin, S., KRAMER, R. A., Rosen, S., Brenya, J., Chavarria, K., Savitska, L., & Keenan, J. P. (2020) · International Journal of Neuroscience · doi:10.1080/00207454.2020.1753729 · Cited by 11
Oğuzhanoğlu, N. K., Sözeri-Varma, G., Karadağ, F., Tümkaya, S., Efe, M., & Kıroğlu, Y. (2014) · PubMed · Cited by 11
Huey, E. D., Fremont, R., Manoochehri, M., Gazes, Y., Lee, S., Cosentino, S., Tierney, M., Wassermann, E. M., Momeni, P., & Grafman, J. H. (2020) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.19100211 · Cited by 10
Self-citationPardini, M., Grafman, J. H., Raymont, V., Amore, M., Serafini, G., Koenigs, M. R., & Krüeger, F. (2019) · CNS Spectrums · doi:10.1017/s1092852918001694 · Cited by 9
Self-citationStupin, K. N., Zenko, M. Y., & Rybnikova, E. A. (2021) · Biochemistry (Moscow) · doi:10.1134/s0006297921060109 · Cited by 9
Guo, Z., Han, X., Kong, T., Wu, Y., Kang, Y., Liu, Y., & Wang, F. (2024) · Scientific Reports · doi:10.1038/s41598-024-58774-5 · Cited by 11
Li, W., Chen, L., Su, T., Li, C., Lin, W., Wu, H.-J., Tsai, S., Bai, Y., Tu, P., & Chen, M. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.05.024 · Cited by 7
Zhang, M., Yang, Y., Zhao, Y., Sui, C., Sui, Y., Jiang, Y., Liu, K., Yang, S., Wang, L., Chen, B., et al. (2024) · Advanced technology in neuroscience . · doi:10.4103/atn.atn-d-24-00018 · Cited by 9
Towards Defining the Neuroanatomical Basis of Late-Onset Psychiatric Symptoms
Barker, M. S., Cosentino, S., Fremont, R., Devanand, D. P., & Huey, E. D. (2022) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/08919887221090213 · Cited by 7
Self-citationLiu, C.-H., Kung, Y., Yeh, T., Hsu, P.-S., Yang, C., Cheng, C.-M., Lin, H.-C., Yang, J.-L., Wu, T., Chang, C., et al. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8070951 · Cited by 7
Shen, X., Toenders, Y. J., Han, L. K. M., Weihs, A., Alexander, N., Andlauer, T. F. M., Brosch, K., Forstner, A. J., Grotegerd, D., Hahn, T., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03136-4 · Cited by 8
Lin, J., Yang, X., Li, H., Lin, W., Zhang, J., & Lei, Y. (2024) · Depression and Anxiety · doi:10.1155/2024/3135532 · Cited by 8
Temperamental Contributions to the Development of Psychological Profiles: II. Two Candidates
Kagan, J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-394427-6.00014-5 · Cited by 7
Serotonin and Emotional Decision-Making
Puig‐Pérez, S. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.81506 · Cited by 6
Towards a neuroimaging biomarker of depression vulnerability
Farb, N. A. S., Segal, Z. V., & Anderson, A. K. (2011) · Translational Neuroscience · doi:10.2478/s13380-011-0033-2 · Cited by 6
“Everything hurts!” Distress in semantic variant primary progressive aphasia
Barker, M. S., Silverman, H. E., Fremont, R., Manoochehri, M., Cosentino, S., & Huey, E. D. (2020) · Cortex · doi:10.1016/j.cortex.2020.03.002 · Cited by 6
Self-citationElmaghraby, R., Blank, E., Miyakoshi, M., Gilbert, D. L., Wu, S. W., Larsh, T., Westerkamp, G., Liu, Y., Horn, P. S., Erickson, C. A., et al. (2025) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2024.0109 · Cited by 5
Neurocircuitry of Anxiety Disorders
Daffre, C., Oliver, K. I., & Pace-Schott, E. F. (2019) · Current clinical psychiatry · doi:10.1007/978-3-030-30687-8_2 · Cited by 6
Treatment Options in Mal de Débarquement Syndrome: A Scoping Review
Kinkhabwala, C. M., Yuen, E., Brennan, E. A., Tejada, A. C., & Rizk, H. G. (2023) · Otology & Neurotology · doi:10.1097/mao.0000000000003832 · Cited by 5
Functional imaging in obese children responding to long-term sports therapy
Kinder, M., Lotze, M., Davids, S., Domín, M., Thoms, K., Wendt, J., Hirschfeld, H., Hamm, A. O., & Lauffer, H. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.06.037 · Cited by 5
Examination of the limbic system's role in emotional experience using a human lesion model
Feinstein, J. S. (2012) · doi:10.17077/etd.hz5d39te · Cited by 5
Xing, H., Liu, X., Zhang, Y., Wu, J., Li, M., Ye, H., Ding, Y., Wang, W., Zheng, Z., & Bao, T. (2025) · Reviews in the Neurosciences · doi:10.1515/revneuro-2024-0151 · Cited by 6
Incorporation of massage into psychotherapy: An integrative and conjoint approach
Posadzki, P., & Bhurke, S. (2011) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-011-0633-2 · Cited by 4
Cognition and nondysphoric depression among adoptees at high risk for psychopathology
Paradiso, S., Caspers, K. M., Tranel, D., & Coryell, W. H. (2010) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2010.10.007 · Cited by 4
Self-citationDepression Complicating Traumatic Brain Injury: The Path to a Poor Prognosis
Rapoport, M. J. (2010) · Psychiatric Annals · doi:10.3928/00485713-20101015-08 · Cited by 4
Examining neural correlates of psychopathology using a lesion-based approach
Calamia, M. R., Markon, K. E., Sutterer, M. J., & Tranel, D. (2018) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2018.06.019 · Cited by 4
Self-citationStewart, J. L., White, E. J., Kuplicki, R., Akeman, E., Bodurka, J., Cha, Y., Feinstein, J. S., Khalsa, S. S., Savitz, J. B., Victor, T. A., et al. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.04.064 · Cited by 4
Stress, Prefrontal Cortex Asymmetry, and Depression
Sullivan, R. M., & Laplante, F. (2011) · Wiley eBooks · doi:10.1002/9781118083222.ch25 · Cited by 4
A circuit-based framework for depression: Reshaping the pathological attractor
Yuan, Z., Quan, J., Cui, Y., & Luo, M. (2026) · Neuron · doi:10.1016/j.neuron.2026.04.009 · Cited by 5
Onwuameze, O. E., & Paradiso, S. (2014) · Psychopathology · doi:10.1159/000360823 · Cited by 3
Carew, C., Tatham, E. L., Milne, A., MacQueen, G., & Hall, G. B. C. (2015) · Journal of Visualized Experiments · doi:10.3791/52061 · Cited by 2
ASPECTOS NEUROPSICOLÓGICOS ASOCIADOS A LA PRESENCIA DE SÍNTOMAS DEPRESIVOS EN NIÑOS ESCOLARIZADOS
Maquet, Y. G., & Valencia, M. (2012) · Cited by 3
Is an Anatomy of Melancholia Possible? Brain Processes, Depression, and Mood Regulation
Forest, D. (2015) · History, philosophy and theory of the life sciences · doi:10.1007/978-94-017-7423-9_7 · Cited by 3
Temperamental Contributions to the Development of Psychological Profiles
Kagan, J. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-375096-9.00012-2 · Cited by 3
Neurocysticercosis: Isolated Lesion in the Left Middle Frontal Gyrus
Mathew, A. S., Clark, C., Lauro, P. M., Khalid, Z., & McLaughlin, N. C. R. (2023) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/acad090 · Cited by 2
Yeung, A., & Rapoport, M. J. (2020) · Brain Injury · doi:10.1080/02699052.2020.1805125 · Cited by 2
Factors associated with utilization of emotion and personality instruments among neuropsychologists
Priluck, J., & Fedio, A. A. (2020) · Applied Neuropsychology Adult · doi:10.1080/23279095.2020.1852238 · Cited by 2
TMS-fMRI Supports Roles for VLPFC and Downstream Regions in Cognitive Reappraisal
Sridhar, M., Azeez, A., & Lissemore, J. I. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.2213-23.2024 · Cited by 2
Stupin, K. N., Зенько, М. Ю., & Rybnikova, E. A. (2021) · Biochemistry (Moscow) · doi:10.31857/s0320972521060105 · Cited by 1
Sequeira‐Cordero, A., & Trías, J. F. (2009) · Americanae (AECID Library) · Cited by 2
Seel, R. T., Macciocchi, S. N., Kreutzer, J. S., Kaelin, D. L., & Katz, D. I. (2011) · European Neurological Review · doi:10.17925/enr.2011.06.01.24 · Cited by 2
Funktionelle Neuroanatomie der Depression
Kammer, T. (2022) · Nervenheilkunde · doi:10.1055/a-1690-0497 · Cited by 2
Dai, H., Hui, J., Wang, D., Ren, L., Lv, Z., Li, J., Yang, Y., Song, J., & Zhang, Z. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.10.084 · Cited by 1
From memory disorders to the development of depression: A system approach
Grigoryan, G. A. (2025) · Biosystems · doi:10.1016/j.biosystems.2025.105440 · Cited by 1
Metadata
- Authors
- Koenigs, M., Huey, E. D., Calamia, M., Raymont, V., Tranel, D., & Grafman, J.
- Affiliations
- University of Wisconsin–Madison (US)
- National Institutes of Health (US)
- University of Iowa (US)
- Henry M. Jackson Foundation (US)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2008-11-19
- Volume
- 28
- Issue
- 47
- Pages
- 12341-12348
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC2644261
- OpenAlex
- W2128478192
- Cited by
- 243
- References
- 58
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 13 · 2023: 11 · 2022: 15 · 2021: 11 · 2020: 17 · 2019: 16 · 2018: 6 · 2017: 19 · 2016: 13 · 2015: 13 · 2014: 18 · 2013: 18 · 2012: 17
- FWCI
- 6.89
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Civil War Book Review (submittedVersion)
- Funders
- National Institutes of Health (Z99 NS999999)
- National Institute on Drug Abuse (R01DA022549)
- National Institute of Neurological Disorders and Stroke (P01 NS19632, P01NS019632, NS-19632, Z01NS002792)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- depression, prefrontal cortex, ventromedial prefrontal cortex, dorsolateral prefrontal cortex, dorsomedial prefrontal cortex, brain lesions, lesion studies, depression vulnerability
- MeSH terms
- Adult, Brain Injuries, Brain Mapping, Cognition Disorders, Depression, Female, Humans, Functional Laterality, Magnetic Resonance Imaging, Male, Middle Aged, Movement Disorders, Severity of Illness Index, Tomography, X-Ray Computed, Veterans, Prefrontal Cortex
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review