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More Than a Small Brain: The Importance of Studying Neural Function during Development

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Sex differences during development in cortical temporal processing and event related potentials in wild-type and fragile X syndrome model mice

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The NKCC1 Inhibitor Bumetanide Restores Cortical Feedforward Inhibition and Lessens Sensory Hypersensitivity in Early Postnatal Fragile X Mice

Kourdougli, N., Nomura, T., Wu, M. W., Heuvelmans, A. M., Dobler, Z., Contractor, A., & Portera‐Cailliau, C. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.06.023 · Cited by 10 · see citing works

Development of GABAergic Inputs Is Not Altered in Early Maturation of Adult Born Dentate Granule Neurons in Fragile X Mice

Remmers, C. L., & Contractor, A. (2018) · eNeuro · doi:10.1523/eneuro.0137-18.2018 · Cited by 10 · see citing works

Iodine Deficiency Exacerbates Thyroidal and Neurological Effects of Developmental Perchlorate Exposure in the Neonatal and Adult Rat

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Tonotopic differentiation of presynaptic neurotransmitter-releasing machinery in the auditory brainstem during the prehearing period and its selective deficits in Fmr1 knockout mice

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Postnatal critical-period brain plasticity and neurodevelopmental disorders: revisited circuit mechanisms

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A comprehensive review of GABA in autism spectrum disorders: associations, mechanisms, and therapeutic implications

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Selective vulnerability of the ventral hippocampus-prelimbic cortex axis parvalbumin interneuron network underlies learning deficits of fragile X mice

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Cortical excitation:inhibition imbalance causes abnormal brain network dynamics as observed in neurodevelopmental disordersPreprint

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Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target

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Advances in Human Stem Cells and Genome Editing to Understand and Develop Treatment for Fragile X Syndrome

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The involvement of neuronal chloride transporter deficiencies in epilepsy

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In Vitro Patch-Clamp

Nomura, T. (2024) · Methods in molecular biology · doi:10.1007/978-1-0716-3810-1_19 · Cited by 2 · see citing works

Targeting GABA Polarity During Cortical Development Improves Circuit and Sensory Deficits in Fragile X Mice

Padmashri, R., & Dunaevsky, A. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.12.006 · Cited by 2 · see citing works

TrkB agonists prevent post-ischemic BDNF-TrkB mediated emergence of refractory neonatal seizures in CD-1 pupsPreprint

Kipnis, P. A., Sullivan, B. J., Carter, B. M., & Kadam, S. D. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2019.12.23.887190 · Cited by 1 · see citing works

Arid1b haploinsufficiency in pyramidal neurons causes cellular and circuit changes in neocortex but is not sufficient to produce behavioral or seizure phenotypesPreprint

Marshall, A. H., Hanson, M. A., Boyle, D. J., Nagarajan, D., Bibi, N., Fitzgerald, J., Gaitten, E., Kokiko‐Cochran, O. N., Gu, B., & Wester, J. C. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.04.597344 · Cited by 1 · see citing works

Restoring Transient Connectivity During Development Improves Dysfunctions in Fragile X MicePreprint

Dumontier, D., Liebman, S. A., Le, V.-H., George, S., Valdemar, D., Aelst, L. V., & Pouchelon, G. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.08.611918 · Cited by 1 · see citing works

Deletion of Fmr1 in Parvalbumin Inhibitory Neurons Leads to Dysregulated Translation and Selective Behavioral Deficits Associated with Fragile X SyndromePreprint

Kalinowska, M., van der Lei, M. B., Kitiashvili, M., Mamcarz, M., Oliveira, M. M., Longo, F., & Klann, E. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3956659

Timing is key in treating sensory traits in fragile X

Askham, A. V. (2022) · The Transmitter · doi:10.53053/ugbv4448

EGR3 Deletion Rescues Developmental and Epileptic Encephalopathy in Kcna1 -null MicePreprint

Mazumder, A. G., Karedia, S., Adhyapak, N., Schimer, C., Bass, J. S., Kamen, J. L., Jankovic, M. J., Miao, Q., Gallitano, A. L., Saltzman, A. B., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.07.658422

Additional file 2 of Deletion of Fmr1 in parvalbumin-expressing neurons results in dysregulated translation and selective behavioral deficits associated with fragile X syndrome

Kalinowska, M., van der Lei, M. B., Kitiashvili, M., Mamcarz, M., Oliveira, M. M., Longo, F., & Klann, E. (2022) · Figshare · doi:10.6084/m9.figshare.20193627

Additional file 1 of Deletion of Fmr1 in parvalbumin-expressing neurons results in dysregulated translation and selective behavioral deficits associated with fragile X syndrome

Kalinowska, M., van der Lei, M. B., Kitiashvili, M., Mamcarz, M., Oliveira, M. M., Longo, F., & Klann, E. (2022) · Figshare · doi:10.6084/m9.figshare.20193624

Dissecting the role of calcium signaling in Fragile X syndrome

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Rôle de la phosphodiestérase 2A dans la physiopathologie du syndrome de l’X fragile

Delhaye, S. (2021) · doi:10.70675/e0fac395z63d4z46a4z944aza4037215ca98

Arid1b haploinsufficiency in excitatory neurons alters neocortical circuits but not social behavior or seizure phenotypes

Marshall, A. H., Hanson, M. A., Boyle, D. J., Nagarajan, D., Bibi, N., Fitzgerald, J., Gaitten, E., Kokiko‐Cochran, O. N., Gu, B., & Wester, J. C. (2026) · Experimental Neurology · doi:10.1016/j.expneurol.2026.115950

Improvement of sensory deficits in fragile X mice by increasing cortical interneuron activity after the critical period

Kourdougli, N., Suresh, A., Liu, B., Juárez, P., Lin, A., Chung, D. T., Sams, A. G., Gandal, M. J., Martínez‐Cerdeño, V., Buonomano, D. V., et al. (2023) · Neuron · doi:10.1016/j.neuron.2023.06.009 · Cited by 68 · see citing works

BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse

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The Developmental Switch in GABA Polarity Is Delayed in Fragile X Mice

He, Q., Nomura, T., Xu, J., & Contractor, A. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.4447-13.2014 · Cited by 230 · see citing works

Targeting GABA Polarity During Cortical Development Improves Circuit and Sensory Deficits in Fragile X Mice

Padmashri, R., & Dunaevsky, A. (2025) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.12.006 · Cited by 2 · see citing works

Dysregulation of GABAA Receptor-Mediated Neurotransmission during the Auditory Cortex Critical Period in the Fragile X Syndrome Mouse Model.

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