Cited by 694Substance Abuse Treatment and OutcomesPsychotherapy Techniques and ApplicationsAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

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Cognitive-Behavioral Treatment With Adult Alcohol and Illicit Drug Users: A Meta-Analysis of Randomized Controlled Trials

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Magill, Molly, Ray, Lara A.·2009·Journal of Studies on Alcohol and Drugs

DOI 10.15288/jsad.2009.70.516PMC PMC2696292

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Abstract

OBJECTIVE: This meta-analysis examined 53 controlled trials of cognitive-behavioral treatment (CBT) for adults diagnosed with alcohol- or illicit-drug-use disorders. The aims were to provide an overall picture of CBT treatment efficacy and to identify client or treatment factors predictive of CBT effect magnitude. METHOD: The inverse variance weighted effect size (Hedges' g) was calculated for each study and pooled using fixed and random effects methods. Potential study-level moderators were assessed in subgroup analyses by primary drug, type of CBT, and type of comparison condition. In addition, seven client and treatment variables were examined in meta-regression analyses. RESULTS: Across studies, CBT produced a small but statistically significant treatment effect (g = 0.154, p < .005). The pooled effect was somewhat lower at 6-9 months (g = 0.1 15, p < .005) and continued to diminish at 12-month follow-up (g = 0.096, p < .05). The effect of CBT was largest in marijuana studies (g = 0.513, p < .005) and in studies with a no-treatment control as the comparison condition (g = 0.796, p < .005). Meta-regression analyses indicated that the percentage of female participants was positively associated and the number of treatment sessions was negatively associated with effect size. CONCLUSIONS: The findings demonstrate the utility of CBT across a large and diverse sample of studies and under rigorous conditions for establishing efficacy. CBT effects were strongest with marijuana users, when CBT was compared with no treatment, and may be larger with women than with men and when delivered in a brief format.

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“Received: March 11, 2013 Accepted: May 03, 2013 Published: May 06, 2013 combined with cognitive-behavioural therapy (CBT) effectively reduces cannabis use [6,7].”
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“49 for CBT with psychosocial interventions, respectively [5]).”
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“The non-medicated consumption of drugs leads to intense craving that has spawned accidents, crime and violence [7].”
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IUPHAR-review: The integration of classic psychedelics into current substance use disorder treatment models
Yaden, D. B., Berghella, A. P., Hendricks, P. S., Yaden, M. E., Levine, M., Rohde, J. S., Nayak, S. M., Johnson, M. W., & Garcia‐Romeu, A. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106998 · Cited by 13
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“…et al., 2010), various anxiety disorders e.g., Hofmann & Smits, 2008), as well as substance use and probems associated with its use (e.g., Magill & Ray, 2009; McHugh, Please cite this article in press as: Milosevic, I., et al. Evaluation of an inte anxiety, and substance use disorders: A pilot…”
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Biological Interventions for Crime Prevention
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“Cognitive-Behavioral Therapy (CBT) has strong empirical support as an efficacious treatment for alcohol use disorders (AUDs; Epstein & McCrady, 2009; Magill & Ray, 2009; Martin & Rehm, 2012; Project MATCH Research Group, 1997, 1998).”
Background
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“24]).(2) Understanding factors related to cocaine use during treatment may facilitate development of more effective treatments.”
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“With more severely affected populations, however, abstinence-based or use-reduction approaches emphasizing drinking moderation or controlled drinking goals [84–87] have been the focus of study in the alcohol intervention literature generally [88–94] and in the naltrexone treatment literature more specifically [95–102].”
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“, a moderate and homogeneous effect of decreasing the days of marijuana use and increasing the days of abstinence, especially in female patients.(54) CM combined with CBT does not appear to have an additional effect in improving cannabis treatment outcomes compared with CBT alone in patients involved with the criminal…”
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“Biological Markers of CBT Response Cognitive behavioral therapy (CBT) is an effective behavioral intervention for drug and alcohol use disorders and its putative active ingredients include learning of skills and strategies for regulating affect, changing maladaptive thoughts, and learning new behavioral strategies.(1,…”
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“There is strong support for its effectiveness in the treatment of alcohol and substance abuse disorders [6], as well as across a wide range of psychiatric conditions [7].”
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“…for the effective alleviation of craving in this treatment modality in patients with methamphetamine dependence is that it raises awareness among them about their previous problematic reactions at the time of craving for drugs (Barrowclough et al., 2009; Brown et al., 2006; Magill & Ray, 2009).”
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“Statistically significant effect sizes are reserved for short-term, cross-sectional research (see, e.g., Mann, Lehert, & Morgan, 2004, for a meta-analysis of acamprosate; Miller, Meyers, Tonigan, & Grant, 2001, for an analysis of Community Reinforcement Approach; Magill & Ray, 2009, for an analysis of Marlatt & Gordon…”
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“These cut points were selected based on prior empirical studies [8] and our intention to capture changes among high-intensity users that could be overlooked if more blunt measures common to RCTs among PWUD, such as daily drug use [44], are used.”
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Authors: Magill, M., & Ray, L. A.
Affiliations: Brown University (US)
ORCID: Magill, Molly
Ray, Lara A.
Venue: Journal of Studies on Alcohol and Drugs
Publisher: Alcohol Research Documentation, Inc.
Published: 2009-07
Volume: 70
Issue: 4
Pages: 516-527
ISSN: 1937-1888 (ISSN-L)
1938-4114
DOI: 10.15288/jsad.2009.70.516
PMC: PMC2696292
OpenAlex: W2035068440
Cited by: 694
References: 111
Citations by year: 2026: 21 · 2025: 32 · 2024: 47 · 2023: 45 · 2022: 37 · 2021: 55 · 2020: 128 · 2019: 45 · 2018: 55 · 2017: 39 · 2016: 34 · 2015: 40 · 2014: 45 · 2013: 32 · 2012: 22
FWCI: 1.55
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Studies on Alcohol and Drugs (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: Boston College
National Institute on Alcohol Abuse and Alcoholism (T32 AA07459-22, AA07459, T32AA007459)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: cognitive behavioral therapy, alcoholism, treatment efficacy, cannabis use, short-term treatment, gender differences
MeSH terms: Adult, Alcoholism, Female, Humans, Male, Sex Characteristics, Time Factors, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Treatment Outcome, Substance-Related Disorders

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Cognitive-Behavioral Treatment With Adult Alcohol and Illicit Drug Users: A Meta-Analysis of Randomized Controlled Trials

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