Methamphetamine dependence and neuropsychological functioning: evaluating change during early abstinence

Simon, Sara L.; Dean, Andy C.; Cordova, Xochitl; Monterosso, John R.; London, Edythe D.

doi:10.15288/jsad.2010.71.335

Cited by 117Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on BehaviorHistorical and Modern Theater Studies

Methamphetamine dependence and neuropsychological functioning: evaluating change during early abstinence

Open access

Simon, Sara L., Dean, Andy C., Cordova, Xochitl, Monterosso, John R., London, Edythe D.·2010·Journal of Studies on Alcohol and Drugs

DOI 10.15288/jsad.2010.71.335PMC PMC2859784

Open this paper in CoChat — free account Open PDF

Abstract

OBJECTIVE: The purpose of this work was to assess neuropsychological functioning of individuals in early abstinence from methamphetamine dependence and to test for cognitive change over the first month of abstinence. METHOD: Methamphetamine-dependent subjects in very early abstinence from methamphetamine (4-9 days; n = 27) were compared with healthy comparison subjects (n = 28) on a test battery that evaluated five cognitive domains (attention/processing speed, learning/memory, working memory, timed executive functioning, and untimed executive functioning). A subsample of the methamphetamine-dependent subjects (n =18), who maintained abstinence for 1 month, as well as a subsample of the comparison subjects (n = 21), were retested. RESULTS: At the first assessment, the methamphetamine-dependent subjects showed significantly worse performance than the comparison group on a test of processing speed; they also performed 0.31 SDs worse than the control group on a global battery composite score (p < .05). After a month of abstinence, methamphetamine-dependent subjects demonstrated slightly more cognitive improvement than healthy control subjects on the entire cognitive battery, but this difference did not approach statistical significance (p = .33). CONCLUSIONS: Our findings suggest that methamphetamine-dependent subjects do not show considerable cognitive gains in the first month of abstinence. A greater length of abstinence may be needed for cognitive improvement.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.15288/jsad.2010.71.335

Cites

61 of 61 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The experience of late protracted withdrawal is linked to mild cognitive dysfunction, particularly in functions involving memory and executive function.
“The experience of this longer, subtle phase of withdrawal is linked to mild cognitive dysfunction (33, 34), particularly in functions involving memory and executive function.”
From Clinical management of psychostimulant withdrawal: review of the evidence (2023) · cites this paper as [33]
The Discussion (page unavailable) reports mildly lowered cognitive scores in methamphetamine-dependent participants during early abstinence. But this study followed participants only through the first month, not a late protracted withdrawal phase. The First assessment section (page unavailable) found a significant difference in attention/processing speed, while memory and executive-function differences did not reach significance. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Methamphetamine-dependent subjects show impaired cognitive abilities (attention, memory, and executive functions) after one month or less of abstinence.
“Methamphetaminedependent subjects show impaired cognitive abilities (i.e., attention, memory, and executive functions) after one month or less of abstinence (Monterosso et al., 2005; Simon et al., 2010).”
From Predictive coding in neuropsychiatric disorders: a systematic transdiagnostic review. (2025) · cites this paper as Simon et al., 2010
The First assessment section reports worse overall battery performance and a significant weakness on one attention/processing-speed test after 4–9 days of abstinence. Learning/memory and timed executive-functioning differences were only trends, not significant findings; the Discussion reports no significant improvement in any domain after about one month. The paper therefore does not establish impairment in all three named domains. (LLM, conf=0.90)
Experimental — accuracy not yet measured

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2022) · doi:10.1176/appi.books.9780890425787 · Cited by 23,476 · see citing works
VALIDITY OF THE TRAIL MAKING TEST AS AN INDICATOR OF ORGANIC BRAIN DAMAGE
Reitan, R. M. (1958) · Perceptual and Motor Skills · doi:10.2466/pms.1958.8.3.271 · Cited by 7,925 · see citing works
Individual differences in working memory and reading
Daneman, M., & Carpenter, P. A. (1980) · Journal of Verbal Learning and Verbal Behavior · doi:10.1016/s0022-5371(80)90312-6 · Cited by 6,336 · see citing works
A standardized set of 260 pictures: Norms for name agreement, image agreement, familiarity, and visual complexity.
Snodgrass, J. G., & Vanderwart, M. (1980) · Journal of Experimental Psychology Human Learning & Memory · doi:10.1037//0278-7393.6.2.174 · Cited by 5,604 · see citing works
A standardized set of 260 pictures: Norms for name agreement, image agreement, familiarity, and visual complexity.
Snodgrass, J. G., & Vanderwart, M. (1980) · Journal of Experimental Psychology Human Learning & Memory · doi:10.1037/0278-7393.6.2.174 · Cited by 3,635 · see citing works
Wisconsin Card Sorting Test Manual – Revised and Expanded
Heaton, R. K., Chelune, C., Talley, J., Kay, G., & Curtiss, G. (1981) · Medical Entomology and Zoology · Cited by 2,975 · see citing works
Stroop Color and Word Test: Manual for Clinical and Experimental Uses.
Golden, C. J., Golden, C. J., & Golden, C. (1978) · NSUWorks (Nova Southeastern University) · Cited by 1,814 · see citing works
Normative Data Stratified by Age and Education for Two Measures of Verbal Fluency FAS and Animal Naming
Tombaugh, T. N., Kozak, J., & Rees, L. M. (1999) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/14.2.167 · Cited by 1,447 · see citing works
The Wender Utah Rating Scale: an aid in the retrospective diagnosis of childhood attention deficit hyperactivity disorder [published erratum appears in Am J Psychiatry 1993 Aug;150(8):1280]
(1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.6.885 · Cited by 1,421 · see citing works
Word fluency and brain damage
Borkowski, J. G., Benton, A. L., & Spreen, O. (1967) · Neuropsychologia · doi:10.1016/0028-3932(67)90015-2 · Cited by 1,324 · see citing works
A Self-Administering Scale for Measuring Intellectual Impairment and Deterioration
Shipley, W. C. (1940) · The Journal of Psychology · doi:10.1080/00223980.1940.9917704 · Cited by 1,238 · see citing works
VALIDITY OF THE TRAIL MAKING TEST AS AN INDICATOR OF ORGANIC BRAIN DAMAGE
Reitan, R. M. (1958) · Perceptual and Motor Skills · doi:10.2466/pms.8.7.271-276 · Cited by 1,088 · see citing works
Woodcock-Johnson psycho-Educational battery
Strein, W. O., & Brantley, J. C. (1981) · Journal of School Psychology · doi:10.1016/0022-4405(81)90061-3 · Cited by 769 · see citing works
Neurocognitive Effects of Methamphetamine: A Critical Review and Meta-analysis
Scott, J. C., Woods, S. P., Matt, G. E., Meyer, R. A., Heaton, R. K., Atkinson, J. H., & Grant, I. (2007) · Neuropsychology Review · doi:10.1007/s11065-007-9031-0 · Cited by 669 · see citing works
The nature, time course and severity of methamphetamine withdrawal
McGregor, C., Srisurapanont, M., Jittiwutikarn, J., Laobhripatr, S., Wongtan, T., & White, J. M. (2005) · Addiction · doi:10.1111/j.1360-0443.2005.01160.x · Cited by 458 · cited 1× · see citing works
“Because the MA withdrawal syndrome peaks within the first 24 hours but can persist for approximately the first week of abstinence (McGregor et al., 2005; consisting primarily of increased appetite and sleep, as well as dysphoria and fatigue), we sought to examine if the number of days of ab- TaBLe…”
Background
Deficits in response inhibition associated with chronic methamphetamine abuse
Monterosso, J. R., Aron, A. R., Cordova, X., Xu, J., & London, E. D. (2005) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2005.02.002 · Cited by 425 · see citing works
Nicotine and smoking: A review of effects on human performance.
Heishma, S. J., Taylor, R. C., & Henningfield, J. E. (1994) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.2.4.345 · Cited by 366 · see citing works
Cognitive Impairment in Individuals Currently Using Methamphetamine
Simon, S. L., Domier, C. P., Carnell, J., Brethen, P., Rawson, R. A., & Ling, W. W. (2000) · American Journal on Addictions · doi:10.1080/10550490050148053 · Cited by 322 · see citing works
Methamphetamine Dependence Is Associated With Neurocognitive Impairment in the Initial Phases of Abstinence
Kalechstein, A. D., Newton, T. F., & Green, M. M. (2003) · Journal of Neuropsychiatry · doi:10.1176/jnp.15.2.215 · Cited by 288 · see citing works
Neuropsychological function and delay discounting in methamphetamine-dependent individuals
Hoffman, W. F., Moore, M., Templin, R., McFarland, B. H., HITZEMANN, R. J., & Mitchell, S. H. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0494-0 · Cited by 287 · see citing works
Pharmacokinetics of methamphetamine self-administered to human subjects by smoking S-(+)-methamphetamine hydrochloride.
Cook, C. E., Jeffcoat, A. R., Hill, J. M., Pugh, D. E., Patetta, P. K., Sadler, B. M., White, W. R., & Perez‐Reyes, M. (1993) · Drug Metabolism and Disposition · doi:10.1016/s0090-9556(25)07478-1 · Cited by 263 · see citing works
Higher Cortical and Lower Subcortical Metabolism in Detoxified Methamphetamine Abusers
Volkow, N. D., Chang, L., Wang, G., Fowler, J. S., Franceschi, D., Sedler, M. J., Gatley, S. J., Hitzemann, R., Ding, Y., Wong, C., et al. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.3.383 · Cited by 249 · see citing works
Practice Effects on Commonly Used Measures of Executive Function Across Twelve Months
Basso, M. R., Bornstein, R. A., & Lang, J. M. (1999) · The Clinical Neuropsychologist · doi:10.1076/clin.13.3.283.1743 · Cited by 245 · see citing works
Partial Recovery of Brain Metabolism in Methamphetamine Abusers After Protracted Abstinence
Wang, G., Volkow, N. D., Chang, L. L., Miller, E. N., Sedler, M. J., HITZEMANN, R. J., Zhu, W., Logan, J., Ma, Y., & Fowler, J. S. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.2.242 · Cited by 241 · see citing works
Cognitive function and nigrostriatal markers in abstinent methamphetamine abusers
Johanson, C.-E., Frey, K. A., Lundahl, L. H., Keenan, P., Lockhart, N., Roll, J., Galloway, G. P., Koeppe, R. A., Kilbourn, M. R., Robbins, T., et al. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0330-6 · Cited by 233 · see citing works
Cognitive Performance of Current Methamphetamine and Cocaine Abusers
Simon, S. L., Domier, C. P., Sim, T., Richardson, K., Rawson, R. A., & Ling, W. W. (2001) · Journal of Addictive Diseases · doi:10.1300/j069v21n01_06 · Cited by 228 · see citing works
Perfusion MRI and computerized cognitive test abnormalities in abstinent methamphetamine users
Chang, L., Ernst, T., Speck, O., Patel, H., DeSilva, M., Leonido–Yee, M., & Miller, E. N. (2002) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(02)00004-5 · Cited by 224 · see citing works
Validity of the SCID in substance abuse patients
Kranzler, H. R., Kadden, R. M., Babor, T. F., Tennen, H. A., & Rounsaville, B. J. (1996) · Addiction · doi:10.1111/j.1360-0443.1996.tb03580.x · Cited by 222 · see citing works
The early time course of smoking withdrawal effects
Hendricks, P. S., Ditre, J. W., Drobes, D. J., & Brandon, T. H. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0429-9 · Cited by 209 · cited 1× · see citing works
“Cognitive dysfunction in smokers has been related to nicotine withdrawal (e.g., Domier et al., 2007; Hendricks et al., 2006; Mendrek et al., 2006), with some effects seen very soon after the cessation of smoking (30-180 minutes).”
Background
Decision making by methamphetamine-dependent subjects is associated with error-rate-independent decrease in prefrontal and parietal activation
Paulus, M. P., Hozack, N. E., Frank, L. R., Brown, G. G., & Schuckit, M. A. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01442-7 · Cited by 208 · see citing works
Enlarged striatum in abstinent methamphetamine abusers: A possible compensatory response
Chang, L., Cloak, C. C., Patterson, K., Grob, C. S., Miller, E. N., & Ernst, T. M. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.01.039 · Cited by 206 · see citing works
Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users
McCann, U. D., Kuwabara, H., Kumar, A., Palermo, M., Abbey, R., Brašić, J. R., Ye, W., Alexander, M., Dannals, R. F., Wong, D. F., et al. (2007) · Synapse · doi:10.1002/syn.20471 · Cited by 205 · see citing works
Nicotinic modulation of neuronal networks: from receptors to cognition
Mansvelder, H. D., van Aerde, K. I., Couey, J. J., & Brussaard, A. B. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0070-z · Cited by 201 · see citing works
Preliminary evidence of reduced cognitive inhibition in methamphetamine-dependent individuals
Salo, R. E., NORDAHL, T. E., Possin, K. L., Leamon, M. H., Gibson, D. R., Galloway, G. P., Flynn, N. M., Henik, A., Pfefferbaum, A., & Sullivan, E. V. (2002) · Psychiatry Research · doi:10.1016/s0165-1781(02)00111-7 · Cited by 187 · see citing works
Working memory in cigarette smokers: Comparison to non-smokers and effects of abstinence
Mendrek, A., Monterosso, J. R., Simon, S. L., Jarvik, M. E., Brody, A. L., Olmstead, R. E., Domier, C. P., Cohen, M. S., Monique Ernst, D., & London, E. D. (2005) · Addictive Behaviors · doi:10.1016/j.addbeh.2005.06.009 · Cited by 161 · see citing works
The bioavailability of intranasal and smoked methamphetamine
Harris, D. E. (2003) · Clinical Pharmacology & Therapeutics · doi:10.1016/j.clpt.2003.08.002 · Cited by 143 · see citing works
The effect of relapse on cognition in abstinent methamphetamine abusers
Simon, S. L., Dacey, J., Glynn, S., Rawson, R., & Ling, W. (2004) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2004.03.011 · Cited by 142 · see citing works
Attentional Control and Brain Metabolite Levels in Methamphetamine Abusers
Salo, R. E., NORDAHL, T. E., Natsuaki, Y., Leamon, M. H., Galloway, G. P., Waters, C., Moore, C. D., & Buonocore, M. H. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.031 · Cited by 139 · see citing works
Neurocognitive performance of methamphetamine users discordant for history of marijuana exposure
González, R., Rippeth, J. D., Carey, C. L., Heaton, R. K., Moore, D. J., Schweinsburg, B. C., Cherner, M., & Grant, I. (2004) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2004.04.014 · Cited by 128 · see citing works
Executive functions among individuals with methamphetamine or alcohol as drugs of choice: Preliminary observations
González, R., Bechara, A., & Martin, E. M. (2006) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390600582446 · Cited by 121 · see citing works
Deficient Strategic Control of Verbal Encoding and Retrieval in Individuals With Methamphetamine Dependence.
Woods, S. P., Rippeth, J. D., Conover, E., Gongvatana, A., González, R., Carey, C. L., Cherner, M., Heaton, R. K., & Grant, I. (2005) · Neuropsychology · doi:10.1037/0894-4105.19.1.35 · Cited by 120 · see citing works
The interactive effects of age and length of abstinence on the recovery of neuropsychological functioning in chronic male alcoholics: A 2-year follow-up study
Rourke, S. B., & Grant, I. (1999) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617799533067 · Cited by 113 · see citing works
Substance abuse and emotion
(2010) · Choice Reviews Online · doi:10.5860/choice.47-3489 · Cited by 113 · see citing works
Substance abuse and emotion.
(2010) · doi:10.1037/12067-000 · Cited by 112 · see citing works
Matching for Education in Studies of Schizophrenia
Resnick, S. M. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820030078011 · Cited by 95 · see citing works
Normative data for the Verbal Selective Reminding Test.
Larrabee, G. J., Trahan, D. E., Curtiss, G., & Levin, H. S. (1988) · Neuropsychology · doi:10.1037/h0091731 · Cited by 81 · see citing works
Dopamine transporters and cognitive function in methamphetamine abuser after a short abstinence: a SPECT study
Chou, Y.-H., Huang, W.-S., Su, T.-P., Lu, R.-B., Wan, F.-J., & Fu, Y.-K. (2007) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.05.002 · Cited by 78 · see citing works
Changes in cerebral glucose metabolism during early abstinence from chronic methamphetamine abuse
Berman, S. M., Voytek, B., Mandelkern, M. A., Hassid, B. D., Isaacson, A. J., Monterosso, J. R., Miotto, K. A., Ling, W. W., & London, E. D. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002107 · Cited by 70 · see citing works
MEMORY IMPAIRMENT IN METHAMPHETAMINE DEPENDENT PATIENTS
MOON, M., Soo, K., Park, J.-W., & Kim, D. (2007) · International Journal of Neuroscience · doi:10.1080/00207450500535503 · Cited by 57 · see citing works
Effects of cigarette smoking and abstinence on stroop task performance
Domier, C. P., Monterosso, J. R., Brody, A. L., Simon, S. L., Mendrek, A., Olmstead, R. E., Jarvik, M. E., Cohen, M. S., & London, E. D. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0869-x · Cited by 47 · see citing works
Retention in Immediate Memory Estimated without Retrieval
Buschke, H. (1963) · Science · doi:10.1126/science.140.3562.56 · Cited by 41 · see citing works
A case of central pontine and extrapontine myelinolysis with early hypermetabolism on 18FDG-PET scan
Roh, J. K., Nam, H. W., & Lee, M. C. (1998) · Journal of Korean Medical Science · doi:10.3346/jkms.1998.13.1.99 · Cited by 41 · see citing works
A dissociation in attentional control: Evidence from methamphetamine dependence
Salo, R. E., NORDAHL, T. E., Moore, C. D., Waters, C., Natsuaki, Y., Galloway, G. P., Kile, S. J., & Sullivan, E. V. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.10.035 · Cited by 41 · see citing works
Relationships among aging, IQ, and intracranial volume in alcoholics and control subjects.
Schottenbauer, M. A., Momenan, R., Kerick, M., & Hommer, D. W. (2007) · Neuropsychology · doi:10.1037/0894-4105.21.3.337 · Cited by 34 · see citing works
Age differences on the California Card Sorting Test: Implications for the assessment of problem solving by the elderly
Beatty, W. W. (1993) · Bulletin of the Psychonomic Society · doi:10.3758/bf03337338 · Cited by 14 · see citing works
The Bioavailability of Intranasal and Smoked Methamphetamine
Mendelson, J. E., Boxenbaum, H., Harris, D. S., Uemura, N., Nath, R. P., Everhart, E. T., & Jones, R. T. (2003) · Clinical Pharmacology & Therapeutics · doi:10.1016/s0009-9236(03)90689-8 · Cited by 12 · see citing works
Normative data for the Verbal Selective Reminding Test.
Larrabee, G. J., Trahan, D. E., Curtiss, G., & Levin, H. S. (1988) · Neuropsychology · doi:10.1037//0894-4105.2.3-4.173 · Cited by 8 · see citing works
A dissociation in attentional control: Evidence from methamphetamine dependence
Salo, R. E., NORDAHL, T. E., MOORE, C., Waters, C., Natsuaki, Y., Galloway, G., Kile, S. J., & Sullivan, E. V. (2005) · Biological Psychiatry · doi:10.1016/j.biopysch.2004.10.035 · Cited by 4 · see citing works
Cerebral deficits associated with impaired cognition and regulation of emotion in methamphetamine abuse.
Dean, A. C., & London, E. D. (2010) · American Psychological Association eBooks · doi:10.1037/12067-010 · Cited by 3 · see citing works
Untitled work
(1985) · doi:10.1002/1097-4679(198509)41:5

Flagged first, then by citations

Research works printed but not linked: 5

Bornstein, R. A. (1985). Normative data on selected neuropsychological measures from a nonclinical sample. Journal of Clinical Psychology, 41, 651-658.
Buschke, H. (1973). Selective reminding of analyses of memory and learn- ing. Journal of Verbal Learning and Verbal Behavior, 12, 543-550.
Jaffe, C., Bush, K. R., Sraits-Troster, K., Meredith, C., Romwall, L., Rosen- baum, G., … Saxon, A. J. (2005). A comparison of methamphetamine- dependent inpatients with and without attention-deficit hyperactivity disorder symptomatology. Journal of Addictive Diseases, 24, 133-152.
Satz, P. (1993). Brain reserve and capacity on symptom onset after brain injury: A formulation and review of evidence for threshold theory. Neuropsychology, 7, 273-295.
Ward, M. F., Wender, P. H., & Reimherr, F. W. (1993). The Wender Utah Rating Scale: An aid in the retrospective diagnosis of childhood at- tention deficit hyperactivity disorder. American Journal of Psychiatry, 150, 885-890.

Sorted by citations

Cognitive deficits in individuals with methamphetamine use disorder: A meta-analysis
Potvin, S., Pelletier, J., Grot, S., Hébert, C., Barr, A. M., & Lecomte, T. (2018) · Addictive Behaviors · doi:10.1016/j.addbeh.2018.01.021 · Cited by 359 · see citing works
Cognitive enhancement as a treatment for drug addictions
Sofuoglu, M., DeVito, E. E., Waters, A. J., & Carroll, K. M. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.06.021 · Cited by 296 · see citing works
An Evaluation of the Evidence that Methamphetamine Abuse Causes Cognitive Decline in Humans
Dean, A. C., Groman, S. M., Morales, A. M., & London, E. D. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.179 · Cited by 251 · see citing works
Is Cognitive Functioning Impaired in Methamphetamine Users? A Critical Review
Hart, C. L., Marvin, C. B., Silver, R., & Smith, E. E. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.276 · Cited by 242 · see citing works
Withdrawal symptoms in abstinent methamphetamine‐dependent subjects
Zorick, T. S., Nestor, L. J., Miotto, K. A., Sugar, C. A., Hellemann, G., Scanlon, G. C., Rawson, R. A., & London, E. D. (2010) · Addiction · doi:10.1111/j.1360-0443.2010.03066.x · Cited by 231 · see citing works
Chronic methamphetamine abuse and corticostriatal deficits revealed by neuroimaging
London, E. D., Kohno, M., Morales, A. M., & Ballard, M. E. (2014) · Brain Research · doi:10.1016/j.brainres.2014.10.044 · Cited by 187 · see citing works
Prefrontal hypoactivation during cognitive control in early abstinent methamphetamine-dependent subjects
Nestor, L. J., Ghahremani, D. G., Monterosso, J. R., & London, E. D. (2011) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2011.04.010 · Cited by 150 · see citing works
Recovery of neurocognitive functions following sustained abstinence after substance dependence and implications for treatment
Schulte, M. H. J., Cousijn, J., den Uyl, T. E., Goudriaan, A. E., van den Brink, W., Veltman, D. J., Schilt, T., & Wiers, R. W. H. J. (2014) · Clinical Psychology Review · doi:10.1016/j.cpr.2014.08.002 · Cited by 150 · see citing works
Gray-matter volume in methamphetamine dependence: Cigarette smoking and changes with abstinence from methamphetamine
Morales, A. M., Lee, B., Hellemann, G., O’Neill, J., & London, E. D. (2012) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2012.02.017 · Cited by 142 · see citing works
Molecular, Behavioral, and Physiological Consequences of Methamphetamine Neurotoxicity: Implications for Treatment
Moszczyńska, A., & Callan, S. P. (2017) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.116.238501 · Cited by 133 · see citing works
Effect of Modafinil on Learning and Task-Related Brain Activity in Methamphetamine-Dependent and Healthy Individuals
Ghahremani, D. G., Tabibnia, G., Monterosso, J. R., Hellemann, G., Poldrack, R. A., & London, E. D. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.233 · Cited by 119 · see citing works
Levels of Neural Progenitors in the Hippocampus Predict Memory Impairment and Relapse to Drug Seeking as a Function of Excessive Methamphetamine Self-Administration
Recinto, P., Samant, A. R. H., Chávez, G., Kim, A., Yuan, C. J., Soleiman, M. T., Grant, Y., Edwards, S., Wee, S., Koob, G. F., et al. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.315 · Cited by 112 · see citing works
Neural Correlates of Affect Processing and Aggression in Methamphetamine Dependence
Payer, D. E., Lieberman, M. D., & London, E. D. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.154 · Cited by 111 · see citing works
Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors
Shin, E., Dang, D., Tran, T.-V., Tran, H., Jeong, J. H., Nah, S.-Y., Jang, C., Yamada, K., Nabeshima, T., & Kim, H. (2017) · Archives of Pharmacal Research · doi:10.1007/s12272-017-0897-y · Cited by 104 · see citing works
Cognitive Function as a Transdiagnostic Treatment Target in Stimulant Use Disorders
Sofuoglu, M., DeVito, E. E., Waters, A. J., & Carroll, K. M. (2016) · Journal of Dual Diagnosis · doi:10.1080/15504263.2016.1146383 · Cited by 101 · see citing works
The Impact of Exercise On Depression and Anxiety Symptoms Among Abstinent Methamphetamine-Dependent Individuals in A Residential Treatment Setting
Rawson, R. A., Chudzynski, J., Gonzales, R., Mooney, L., Dickerson, D., Ang, A., Dolezal, B., & Cooper, C. B. (2015) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2015.04.007 · Cited by 90 · see citing works
Pharmacological treatments for methamphetamine addiction: current status and future directions
Ballester, J., Valentine, G. W., & Sofuoglu, M. (2016) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2017.1268916 · Cited by 89 · see citing works
The cognitive impairments and psychological wellbeing of methamphetamine dependent patients compared with health controls
Zhong, N., Jiang, H., Du, J., Zhao, Y. F., Sun, H., Xu, D., Li, C., Zhuang, W., Li, X., Hashimoto, K., et al. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.04.005 · Cited by 84 · see citing works
The neurobiological mechanisms of physical exercise in methamphetamine addiction
Morais, A., Pita, I. R., Ribeiro, C., & Pereira, F. C. (2017) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12788 · Cited by 78 · see citing works
Acute Modafinil Effects on Attention and Inhibitory Control in Methamphetamine-Dependent Humans
Dean, A. C., Sevak, R. J., Monterosso, J. R., Hellemann, G., Sugar, C. A., & London, E. D. (2011) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2011.72.943 · Cited by 79 · see citing works
Methamphetamine abuse disturbs the dopaminergic system to impair hippocampal-based learning and memory: An overview of animal and human investigations
Shukla, M., & Vincent, B. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.09.016 · Cited by 72 · see citing works
Modafinil improves methamphetamine-induced object recognition deficits and restores prefrontal cortex ERK signaling in mice
González, B., Raineri, M., Cadet, J. L., García‐Rill, E., Urbano, F. J., & Bisagno, V. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.02.002 · Cited by 58 · see citing works
Denial in methamphetamine users: Associations with cognition and functional connectivity in brain
Dean, A. C., Kohno, M., Morales, A. M., Ghahremani, D. G., & London, E. D. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.03.004 · Cited by 53 · see citing works
Functional and Structural Brain Changes Associated with Methamphetamine Abuse
Jan, R. K., Kydd, R. R., & Russell, B. R. (2012) · Brain Sciences · doi:10.3390/brainsci2040434 · Cited by 51 · see citing works
Impulsivity predicts poorer improvement in quality of life during early treatment for people with methamphetamine dependence
Rubenis, A. J., Fitzpatrick, R. E., Lubman, D. I., & Verdejo‐García, A. (2017) · Addiction · doi:10.1111/add.14058 · Cited by 48 · see citing works
Cognition and Related Neural Findings on Methamphetamine Use Disorder: Insights and Treatment Implications From Schizophrenia Research
Guerin, A. A., Bonomo, Y. A., Lawrence, A. J., Baune, B. T., Nestler, E. J., Rossell, S. L., & Kim, J. H. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00880 · Cited by 48 · see citing works
Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cycle
Yuan, C. J., Quiocho, J., Kim, A., Wee, S., & Mandyam, C. D. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.08.004 · Cited by 45 · see citing works
Effects of exposure to amphetamine derivatives on passive avoidance performance and the central levels of monoamines and their metabolites in mice: Correlations between behavior and neurochemistry
Murnane, K. S., Perrine, S. A., Finton, B. J., Galloway, M. P., Howell, L. L., & Fantegrossi, W. E. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2504-0 · Cited by 43 · see citing works
Predicting adherence to treatment for methamphetamine dependence from neuropsychological and drug use variables
Dean, A. C., London, E. D., Sugar, C. A., Ramirez, C. M., Swanson, A., Heinzerling, K. G., Kalechstein, A. D., & SHOPTAW, S. J. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.06.008 · Cited by 43 · see citing works
The effects of modafinil treatment on neuropsychological and attentional bias performance during 7-day inpatient withdrawal from methamphetamine dependence.
Hester, R., Lee, N., Pennay, A., Nielsen, S., & Ferris, J. (2010) · Experimental and Clinical Psychopharmacology · doi:10.1037/a0021791 · Cited by 42 · see citing works
Cognitive deficit in methamphetamine users relative to childhood academic performance: link to cortical thickness
Dean, A. C., Morales, A. M., Hellemann, G., & London, E. D. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0065-1 · Cited by 39 · see citing works
A meta-analysis of the relationship between abstinence and neuropsychological functioning in methamphetamine use disorder.
Basterfield, C., Hester, R., & Bowden, S. C. (2019) · Neuropsychology · doi:10.1037/neu0000552 · Cited by 43 · see citing works
HIV and Chronic Methamphetamine Dependence Affect Cerebral Blood Flow
Ances, B. M., Vaida, F., Cherner, M., Yeh, M. J., Liang, C. L., Gardner, C. S., Grant, I., Ellis, R. J., & Buxton, R. B. (2011) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-011-9270-y · Cited by 41 · see citing works
Evidence-Based Guidelines for the Pharmacologic Management of Methamphetamine Dependence, Relapse Prevention, Chronic Methamphetamine-Related, and Comorbid Psychiatric Disorders in Post-Acute Settings
Härtel-Petri, R., Krampe-Scheidler, A., Braunwarth, W.-D., Havemann-Reinecke, U., Jeschke, P., Looser, W., Mühlig, S., Schäfer, I., Scherbaum, N., Bothe, L., et al. (2017) · Pharmacopsychiatry · doi:10.1055/s-0043-105500 · Cited by 39 · see citing works
Methamphetamine-induced short-term increase and long-term decrease in spatial working memory affects protein Kinase M zeta (PKMζ), dopamine, and glutamate receptors
Braren, S. H., Drapala, D., Tulloch, I. K., & Serrano, P. A. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00438 · Cited by 39 · see citing works
Methamphetamine withdrawal and the restoration of cognitive functions – a study over a course of 6 months abstinence
Proebstl, L., Krause, D., Kamp, F., Hager, L., Manz, K. M., Schacht-Jablonowsky, M., Straif, M., Riebschläger, M., Neumann, S., Anne, S., et al. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.112599 · Cited by 39 · see citing works
Clinical management of psychostimulant withdrawal: review of the evidence
Li, M. J., & Shoptaw, S. J. (2023) · Addiction · doi:10.1111/add.16093 · Cited by 39 · see citing works
Neuropsychological comparisons of cocaine versus methamphetamine users: A research synthesis and meta-analysis
Hall, M. G., Hauson, A. O., Wollman, S. C., Allen, K. E., Connors, E. J., Stern, M. J., Kimmel, C. L., Stephan, R. A., Sarkissians, S., Barlet, B. D., et al. (2017) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2017.1355919 · Cited by 37 · see citing works
Cognitive profile of ketamine-dependent patients compared with methamphetamine-dependent patients and healthy controls
Wang, L., Chen, C., Lin, S., Chen, Y., Xu, K., & Huang, M. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4910-z · Cited by 37 · see citing works
Distributed attentional deficits in chronic methamphetamine abusers: Evidence from the Attentional Network Task (ANT)
Salo, R. E., Gabay, S., Fassbender, C., & Henik, A. (2011) · Brain and Cognition · doi:10.1016/j.bandc.2011.08.012 · Cited by 30 · see citing works
Reduced Neural Recruitment for Bayesian Adjustment of Inhibitory Control in Methamphetamine Dependence
Harlé, K. M., Zhang, S., Ma, N., Yu, A. J., & Paulus, M. P. (2016) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2016.06.008 · Cited by 29 · see citing works
Gray-matter structure in long-term abstinent methamphetamine users
Nie, L., Zhao, Z., Wen, X., Luo, W. F., Ju, T., Ren, A., Wu, B., & Li, J. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02567-3 · Cited by 28 · see citing works
Neurocognitive and psychiatric dimensions of hot, but not cool, impulsivity predict HIV sexual risk behaviors among drug users in protracted abstinence
Wilson, M. J., & Vassileva, J. (2016) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952990.2015.1121269 · Cited by 27 · see citing works
Effects of a Group-Based Aerobic Exercise Program on the Cognitive Functions and Emotions of Substance Use Disorder Patients: a Randomized Controlled Trial
Zhu, T., Tao, W., Peng, B., Su, R., Wang, D., Hu, C. Y., & Chang, Y. (2021) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-021-00518-x · Cited by 28 · see citing works
The role of hippocampal adult neurogenesis in methamphetamine addiction
Takashima, Y., & Mandyam, C. D. (2017) · Brain Plasticity · doi:10.3233/bpl-170058 · Cited by 27 · see citing works
Goofballing of Opioid and Methamphetamine: The Science Behind the Deadly Cocktail
Hazani, H. M., Mohamed, I. N., Mustapha, M., Mohamed, W. M. Y., Yahaya, M. F., Teoh, S. L., Mohamed, R. M. P., Isa, M. F. M., Abdulrahman, S. M., Ramadah, R., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.859563 · Cited by 25 · see citing works
Structural, Functional and Spectroscopic MRI Studies of Methamphetamine Addiction
Salo, R. E., & Fassbender, C. (2011) · Current topics in behavioral neurosciences · doi:10.1007/7854_2011_172 · Cited by 26 · see citing works
Predictive coding in neuropsychiatric disorders: a systematic transdiagnostic review.
Qela, B., Damiani, S., De Santis, S., Groppi, F., Pichiecchio, A., Asteggiano, C., Brondino, N., Monteleone, A. M., Grassi, L., Politi, P., et al. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106020 · Cited by 26 · see citing works
“…methamphetamine addicts showed impaired predictive ability and greater inflexibility than HCs. Methamphetamine-dependent subjects show impaired cognitive abilities (i.e., attention, memory, and executive functions) after one month or less of abstinence (Monterosso et al., 2005; Simon et al., 2010).”
Working memory predicts methamphetamine hair concentration over the course of treatment: moderating effect of impulsivity and implications for dual‐systems model
Rubenis, A. J., Fitzpatrick, R. E., Lubman, D. I., & Verdejo‐García, A. (2017) · Addiction Biology · doi:10.1111/adb.12575 · Cited by 24 · see citing works
The relationship between duration of abstinence and gray-matter brain structure in chronic methamphetamine users
Nie, L., Ghahremani, D. G., Mandelkern, M. A., Dean, A. C., Luo, W. F., Ren, A., Li, J., & London, E. D. (2021) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2020.1778712 · Cited by 24 · see citing works
Hazards of Illicit Methamphetamine Production and Efforts at Reduction: Data from the Hazardous Substances Emergency Events Surveillance System
Melnikova, N., Welles, W. L., Wilburn, R. E., Rice, N., Wu, J., & Stanbury, M. J. (2011) · Public Health Reports · doi:10.1177/00333549111260s115 · Cited by 24 · see citing works
Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic Methamphetamine Exposure
Wu, Y., Dong, Z.-Y., Jiang, X., Qu, L., Zhou, W., Sun, X., Hou, J., Xu, H., & Cheng, M. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.00302-23 · Cited by 24 · see citing works
More Alike than Different: Health Needs, Services Utilization, and Outcomes of Asian American and Pacific Islander (AAPI) Populations Treated for Substance Use Disorders
Evans, E., Pierce, J. M., Li, L., Rawson, R. A., & Hser, Y. (2012) · Journal of Ethnicity in Substance Abuse · doi:10.1080/15332640.2012.735172 · Cited by 22 · see citing works
MMP-9-BDNF pathway is implicated in cognitive impairment of male individuals with methamphetamine addiction during early withdrawal
Cheng, M., Liu, Q., Wang, Y., Hao, Y., Jing, P., Jiao, S., Ma, L., Pan, C., & Wu, Y. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.03.020 · Cited by 22 · see citing works
An Update of the Review of Neuropsychological Consequences of HIV and Substance Abuse: A Literature Review and Implications for Treatment and Future Research
Norman, L. R., & Basso, M. R. (2015) · Current Drug Abuse Reviews · doi:10.2174/1874473708666150309124820 · Cited by 19 · see citing works
Overlapping Cognitive Patterns in Schizophrenia and Methamphetamine Dependence
Salo, R. E., Ravizza, S. M., & Fassbender, C. (2011) · Cognitive and Behavioral Neurology · doi:10.1097/wnn.0b013e31823fc1d0 · Cited by 19 · see citing works
Relationship of Age to Impulsivity and Decision Making: A Baseline Secondary Analysis of a Behavioral Treatment Study in Stimulant Use Disorders
Kalapatapu, R. K., Lewis, D. F., Vinogradov, S., Batki, S. L., & Winhusen, T. M. (2013) · Journal of Addictive Diseases · doi:10.1080/10550887.2013.795471 · Cited by 18 · see citing works
Educational attainment is not a good proxy for cognitive function in methamphetamine dependence
Dean, A. C., Hellemann, G., Sugar, C. A., & London, E. D. (2011) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2011.11.019 · Cited by 17 · see citing works
Striatal Dopamine D2/D3 Receptor Availability Is Associated with Executive Function in Healthy Controls but Not Methamphetamine Users
Ballard, M. E., Dean, A. C., Mandelkern, M. A., & London, E. D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0143510 · Cited by 17 · see citing works
Distribution of Methamphetamine and Its Metabolite Amphetamine in Acute and Subacute Ethanol-Methamphetamine Combination Abuse Model Rats
Liang, M., Liu, Y., Zheng, N., Ananda, S., & Liu, L. (2012) · Journal of Analytical Toxicology · doi:10.1093/jat/bkr007 · Cited by 16 · see citing works
Methamphetamine dependence in Australia–why is ‘ice’ (crystal meth) so addictive?
Scott, R. J. (2023) · Psychiatry Psychology and Law · doi:10.1080/13218719.2023.2206870 · Cited by 14 · see citing works
The spatial learning and memory performance in methamphetamine-sensitized and withdrawn rats.
Bigdeli, I., Asia, M. N.-H., Miladi‐Gorji, H., & Fadaei, A. (2015) · Europe PMC (PubMed Central) · Cited by 14 · see citing works
Neurocognitive Dysfunctions and Their Therapeutic Modulation in Patients With Methamphetamine Dependence: A Pilot Study
Bernhardt, N. R., Petzold, J., Groß, C., Scheck, A., Pooseh, S., Mayer-Pelinski, R., Zimmermann, U. S., Smolka, M. N., & Pilhatsch, M. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00581 · Cited by 14 · see citing works
CYP2D6 genotype may moderate measures of brain structure in methamphetamine users
Dean, A. C., Nurmi, E. L., Morales, A. M., Cho, A. K., Seaman, L. C., & London, E. D. (2020) · Addiction Biology · doi:10.1111/adb.12950 · Cited by 13 · see citing works
Functional interactions of HIV-infection and methamphetamine dependence during motor programming
Archibald, S. L., Jacobson, M. W., Fennema‐Notestine, C., Ogasawara, M., Woods, S. P., Letendre, S. L., Grant, I., & Jernigan, T. L. (2012) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2012.03.006 · Cited by 13 · see citing works
Prävalenz und Therapie bei Abhängigkeit von Methamphetamin („Crystal“)
Soyka, M., Koller, G., Proebstl, L., Kamp, F., Franke, A. G., Schmidt, P., Baumgärtner, G., Schacht-Jablonowsky, M., Sievert, A., Straif, M., et al. (2017) · Fortschritte der Neurologie · Psychiatrie · doi:10.1055/s-0042-119862 · Cited by 13 · see citing works
Effects of intrastriatal dopamine D1 or D2 antagonists on methamphetamine-induced egocentric and allocentric learning and memory deficits in Sprague–Dawley rats
Gutierrez, A., Regan, S. L., Hoover, C. S., Williams, M. T., & Vorhees, C. V. (2019) · Psychopharmacology · doi:10.1007/s00213-019-05221-3 · Cited by 13 · see citing works
Impulse Inhibition Ability With Methamphetamine Dependents Varies at Different Abstinence Stages
Liu, W., Tian, Y., Yan, X., & Yang, J. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.626535 · Cited by 13 · see citing works
Effect of fendiline on the maintenance and expression of methamphetamine-induced conditioned place preference in Sprague–Dawley rats
Voigt, R. M., Riddle, J. L., & Napier, T. C. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3347-7 · Cited by 12 · see citing works
Voluntary oral methamphetamine increases memory deficits and contextual sensitization during abstinence associated with decreased PKMζ and increased κOR in the hippocampus of female mice
Avila, J. A., Memos, N. K., Aslan, A., Andrejewski, T., Luine, V. N., & Serrano, P. A. (2021) · Journal of Psychopharmacology · doi:10.1177/02698811211048285 · Cited by 12 · see citing works
Cognition during active methamphetamine use versus remission
Huckans, M. S., Boyd, S. J., Moncrief, G. G., Hantke, N. C., Winters, B., Shirley, K., Sano, E., McCready, H. D., Dennis, L. E., Kohno, M., et al. (2021) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2021.1976734 · Cited by 12 · see citing works
The impact of methamphetamine use and dependence: A systematic review on the cognitive-behavioural implications for road safety
Love, S., Nicolls, M., Rowland, B., & Davey, J. D. (2024) · Transportation Research Part F Traffic Psychology and Behaviour · doi:10.1016/j.trf.2024.05.002 · Cited by 12 · see citing works
Pharmacological cognitive enhancers
Peltier, M. R., & Sofuoglu, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815298-0.00023-x · Cited by 9 · see citing works
Neuropharmacological Evidence Implicating Drug-Induced Glutamate Receptor Dysfunction in Affective and Cognitive Sequelae of Subchronic Methamphetamine Self-Administration in Mice
Denning, C. J. E., Madory, L. E., Herbert, J. N., Cabrera, R. A., & Szumlinski, K. K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031928 · Cited by 10 · see citing works
Executive Dysfunction in Addiction
Verdejo‐García, A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803676-1.00016-7 · Cited by 10 · see citing works
Sustained attention but not effort-based decision-making predicts treatment motivation change in people with methamphetamine dependence
Rubenis, A. J., Fitzpatrick, R. E., Lubman, D. I., & Verdejo‐García, A. (2018) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2018.09.007 · Cited by 9 · see citing works
Lack of longitudinal changes in cognition in individuals with methamphetamine use disorder during the first 6 weeks after commencing treatment
Fitzpatrick, R. E., Robinson, A. H., Rubenis, A. J., Lubman, D. I., & Verdejo‐García, A. (2021) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990.2020.1869243 · Cited by 9 · see citing works
Disruption of regional homogeneity in the brains of chronic methamphetamine users
Nie, L., Wen, X., Luo, W., Ju, T., Ren, A., Wu, B., Li, J., & Hu, J. (2022) · Brain Imaging and Behavior · doi:10.1007/s11682-022-00637-6 · Cited by 8 · see citing works
The effects of early exposure to MK-801 during environmental enrichment on spatial memory, methamphetamine self-administration and cue-induced renewal in rats
Zhang, P., Pan, J., Mao, Z., Xu, X., Lin, D., Wu, B., Zhou, W., & Liu, Y. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.01.032 · Cited by 8 · see citing works
Sex differences in behavior, cognitive, and physiological recovery following methamphetamine administration
Armenta-Reséndiz, M., Carter, J. S., Hunter, Z., Taniguchi, M., Reichel, C. M., & Lavı́n, A. (2024) · Psychopharmacology · doi:10.1007/s00213-024-06638-1 · Cited by 7 · see citing works
Mini mental state examination (MMSE) in substance users and non substance users: A comparison study
Shakeri, J., Farnia, V., Golshani, S., Rahami, B., Salemi, S., Hookari, S., Alikhani, M., & Abdoli, N. (2020) · Journal of Substance Use · doi:10.1080/14659891.2020.1779360 · Cited by 7 · see citing works
Functionally Relevant Brain Alterations in Polysubstance Users
Meyerhoff, D. J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805373-7.00021-9 · Cited by 7 · see citing works
Methamphetamine abuse impairs sequential working memory
Wang, Y., Zhang, H., Li, S., Song, S., Ye, Z., & Zhou, X. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1458509 · Cited by 6 · see citing works
Memory and Executive Function Deficits in Abstinent Patients with Methamphetamine Use Disorder
Salas-González, C., Gudayol‐Ferré, E., Villuendas‐González, E. R., Blázquez, F. P., Ramírez, V. G., & Murillo-Servín, A. K. (2022) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-022-00939-2 · Cited by 9 · see citing works
Does chronic use of amphetamine-type stimulants impair interference control? – A meta-analysis
Opitz, A., Petasch, M.-S., Klappauf, R., Kirschgens, J., Hinz, J. R., Dittmann, L., Dathe, A. S., Quednow, B. B., Beste, C., & Stock, A. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.105020 · Cited by 6 · see citing works
Modeling neurocognitive and neurobiological recovery in addiction
Meyerhoff, D. J., & Durazzo, T. C. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815298-0.00028-9 · Cited by 6 · see citing works
The Effectiveness of Mindfulness in the Treatment of Methamphetamine Addiction Symptoms: Does Neuroplasticity Play a Role?
Chmiel, J., Malinowska, A., Rybakowski, F., & Leszek, J. (2024) · Brain Sciences · doi:10.3390/brainsci14040320 · Cited by 8 · see citing works
Adaptive Changes in Group 2 Metabotropic Glutamate Receptors Underlie the Deficit in Recognition Memory Induced by Methamphetamine in Mice
Busceti, C. L., Menna, L. D., Castaldi, S., D’Errico, G., Taddeucci, A., Bruno, V., Fornai, F., Pittaluga, A., Battaglia, G., & Nicoletti, F. (2024) · eNeuro · doi:10.1523/eneuro.0523-23.2024 · Cited by 5 · see citing works
Attention Deficits in Chronic Methamphetamine Users as a Potential Target for Enhancing Treatment Efficacy
Mehrjerdi, Z. A., Noroozi, A., Barr, A. M., & Ekhtiari, H. (2012) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 5 · see citing works
Efficacy of Working Memory training on Craving and Cognitive Functioning of Opiate Users
Bagheri, Z., Hassani‐Abharian, P., Armani, A., Taromian, F., Bytamar, J. M., Molavi, N., & Moradi, A. (2018) · Clinical and Experimental Psychology · doi:10.4172/2471-2701.1000202 · Cited by 4 · see citing works
Factors affecting the occurrence of psychotic symptoms in chronic methamphetamine users
Nie, L., Zhaom, Z., Wen, X., Luo, W. F., Ju, T., Ren, A., Wu, B., London, E. D., & Li, J. (2018) · Journal of Addictive Diseases · doi:10.1080/10550887.2019.1661752 · Cited by 4 · see citing works
Bias Toward Drug-Related Stimuli Is Affected by Loading Working Memory in Abstinent Ex-Methamphetamine Users
Deldar, Z., Ekhtiari, H., Pouretemad, H. R., & Khatibi, A. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00776 · Cited by 4 · see citing works
Synaptic remodeling of GluA1 and GluA2 expression in the nucleus accumbens promotes susceptibility to cognitive deficits concomitant with downstream GSK3β mediated neurotoxicity in female mice during abstinence from voluntary oral methamphetamine
Memos, N. K., Avila, J. A., Rodriguez, E., & Serrano, P. A. (2023) · Addiction Neuroscience · doi:10.1016/j.addicn.2023.100112 · Cited by 3 · see citing works
Effects of High‐Frequency rTMS Combined With Physical Exercise on Mood Disorders in Patients With Methamphetamine Use Disorder: A Randomized Clinical Trial
Wang, K., Li, Y., Yang, Y., Zhang, T., & Luo, J. (2026) · Depression and Anxiety · doi:10.1155/da/6470779 · Cited by 3 · see citing works
Individuals recently abstinent from methamphetamine show selective cognitive and behavioral differences when compared to age-matched controls
Vest, M. F., Dumitrescu, A. M., Johnson, M. W., Thompson, E., Thomas, A., Patterson, J. C., & Murnane, K. S. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1604252 · Cited by 3 · see citing works
Abnormal regional brain activity associated with relapse in early abstinent methamphetamine-dependent individuals
Ma, M., Yu, T., Qin, Z., Zhao, P., Zhao, M., Guo, J., Huang, N., Liu, M., Zhang, K., Cai, Q., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-11438-4 · Cited by 2 · see citing works
Serum brain-derived neurotrophic factor levels in patients with schizophrenia and methamphetamine addiction: correlation with Mini-Mental State Examination (MMSE)
Mohammed, S. M., Hashim, Z. H., Hussein, M. M., & Al-Mayah, Q. S. (2023) · Journal of Medicine and Life · doi:10.25122/jml-2022-0250 · Cited by 2 · see citing works
A Comparative Study on Visual Memory and Reaction Time in Students With Specific Learning Disability (SLD) and Normal Children
Kargar, F., & Talebi, S. (2022) · ناتوانی های یادگیری · doi:10.32598/jld.10.2.4 · Cited by 2 · see citing works
Multimodal Magnetic Resonance Neuroimaging and Cognition in Polysubstance Users
Meyerhoff, D. J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800634-4.00086-x · Cited by 2 · see citing works
The Effectiveness of Computerized Cognitive Rehabilitation in Improving Response Inhibition and Working Memory in Adolescents with Tendency to Substance Use
abdolmohamamadi, K., Mohammadzadeh, A., & غدیری, ف. (2023) · فصلنامه علمی و پژوهشی اعتیادپژوهی · doi:10.52547/etiadpajohi.16.66.71 · Cited by 1 · see citing works

Methamphetamine Dependence Is Associated With Neurocognitive Impairment in the Initial Phases of Abstinence
Kalechstein, A. D., Newton, T. F., & Green, M. M. (2003) · Journal of Neuropsychiatry · doi:10.1176/jnp.15.2.215 · Cited by 288 · see citing works
A meta-analysis of the relationship between abstinence and neuropsychological functioning in methamphetamine use disorder.
Basterfield, C., Hester, R., & Bowden, S. C. (2019) · Neuropsychology · doi:10.1037/neu0000552 · Cited by 43 · see citing works
The cognitive impairments and psychological wellbeing of methamphetamine dependent patients compared with health controls
Zhong, N., Jiang, H., Du, J., Zhao, Y. F., Sun, H., Xu, D., Li, C., Zhuang, W., Li, X., Hashimoto, K., et al. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.04.005 · Cited by 84 · see citing works
Methamphetamine withdrawal and the restoration of cognitive functions – a study over a course of 6 months abstinence
Proebstl, L., Krause, D., Kamp, F., Hager, L., Manz, K. M., Schacht-Jablonowsky, M., Straif, M., Riebschläger, M., Neumann, S., Anne, S., et al. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.112599 · Cited by 39 · see citing works
Longer term improvement in neurocognitive functioning and affective distress among methamphetamine users who achieve stable abstinence
Iudicello, J. E., Woods, S. P., Vigil, O., Scott, J. C., Cherner, M., Heaton, R. K., Atkinson, J. H., Grant, I., & Ce, T. H. N. R. (2010) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390903512637 · Cited by 111 · see citing works

Authors: Simon, S. L., Dean, A. C., Cordova, X., Monterosso, J. R., & London, E. D.
Affiliations: University of California, Los Angeles (US)
University of Southern California (US)
ORCID: Dean, Andy C.
Monterosso, John R.
London, Edythe D.
Venue: Journal of Studies on Alcohol and Drugs
Publisher: Alcohol Research Documentation, Inc.
Published: 2010-05
Volume: 71
Issue: 3
Pages: 335-344
ISSN: 1937-1888 (ISSN-L)
1938-4114
DOI: 10.15288/jsad.2010.71.335
PMC: PMC2859784
OpenAlex: W2094075971
Cited by: 117
References: 60
Citations by year: 2026: 2 · 2025: 5 · 2024: 7 · 2023: 8 · 2022: 8 · 2021: 9 · 2020: 5 · 2019: 9 · 2018: 6 · 2017: 12 · 2016: 7 · 2015: 6 · 2014: 4 · 2013: 3 · 2012: 8
FWCI: 6.51
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Studies on Alcohol and Drugs (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Institute on Drug Abuse (R01DA015179, DA-50038, DA 15179, P20DA022539, DA 022539, R01DA020726, DA 020726)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
Keywords: methamphetamine dependence, early abstinence, cognitive recovery, neuropsychological performance, processing speed, attention, working memory, executive function, learning and memory, drug addiction
MeSH terms: Adult, Cognition Disorders, Female, Humans, Longitudinal Studies, Male, Memory Disorders, Methamphetamine, Neuropsychological Tests, Time Factors, Case-Control Studies, Amphetamine-Related Disorders, Executive Function

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Methamphetamine dependence and neuropsychological functioning: evaluating change during early abstinence

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks