Longitudinal Effects of Early Childhood Maltreatment on Co-Occurring Substance Misuse and Mental Health Problems in Adulthood: The Role of Adolescent Alcohol Use and Depression
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OBJECTIVE: This study tested a developmental model in which subtypes of childhood maltreatment were hypothesized to have direct and indirect effects on co-occurring depression, anxiety, and substance misuse in adulthood. Indirect effects involved adolescent alcohol use and depression, which were included as mediators in the tested models. METHOD: This prospective longitudinal study (N = 332; 52.4% male) followed the participants from childhood (18 months to 6 years of age) to adulthood (31-41 years old, M = 36.21). Maltreatment subtypes included parent-reported physical and emotional abuse and child-reported sexual abuse. Adult outcomes included measures of substance misuse and mental health (i.e., depression and anxiety). Latent class analysis and structural equation models were used to identify classes of substance misuse and mental health co-occurrence and to test mediating effects of adolescent alcohol use and depression. RESULTS: Three classes were identified: (a) low risk of substance misuse and low mental health symptoms, (b) moderate substance misuse risk and mild depression and anxiety, and (c) moderate substance misuse risk and moderate to high depression and anxiety. Structural models showed that effects of childhood sexual abuse were fully mediated by adolescent alcohol use and depression. Physical abuse increased adolescent depression but did not have direct or indirect effects on adult outcome classes. Emotional abuse had a direct effect on the adult classes. CONCLUSIONS: Children exposed to severe emotional abuse are at higher risk for comorbid substance misuse, depression, and anxiety into their mid-30s, after taking into account evidence of alcohol use and depression during adolescence. Sexual and physical abuse have more proximal effects on adolescent alcohol use and depression, which then influence the risk of adult problems.
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Childhood trauma increases the risk of internet addiction.
“Previous findings have shown that childhood trauma increases the risk of behaviours such as substance abuse and internet addiction (Skinner et al., 2016; Worsley et al., 2018).”
From The relationship between childhood trauma and internet addiction in adolescents: A meta-analysis (2024) · cites this paper as Skinner et al., 2016
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- Authors
- Skinner, M. L., Hong, S., Herrenkohl, T. I., Brown, E. C., Lee, J. O., & Jung, H.
- Affiliations
- University of Washington (US)
- University of Hawaiʻi at Mānoa (US)
- University of Miami (US)
- University of Southern California (US)
- Corresponding author
- Hong, Seunghye
- Venue
- Journal of Studies on Alcohol and Drugs
- Publisher
- Alcohol Research Documentation, Inc.
- Published
- 2016-05
- Volume
- 77
- Issue
- 3
- Pages
- 464-472
- ISSN
- 1937-1888 (ISSN-L)
- 1938-4114
- PMC
- PMC4869903
- OpenAlex
- W2388703698
- Cited by
- 56
- References
- 31
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 5 · 2023: 6 · 2022: 11 · 2021: 7 · 2020: 10 · 2019: 5 · 2018: 1 · 2017: 2 · 2016: 1
- FWCI
- 4.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Studies on Alcohol and Drugs (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01hd049767-04)
- National Institute on Drug Abuse (R01DA032950)
- Office of Behavioral and Social Sciences Research
- National Institute on Minority Health and Health Disparities (U54MD007584)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01 HD049767))
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Social Sciences › Safety Research › Child Welfare and Adoption
- Keywords
- child abuse, substance abuse, depression, anxiety, adolescent alcohol use, emotional abuse, physical abuse, sexual abuse, psychiatric comorbidity, mediation, developmental pathways, adult outcomes
- MeSH terms
- Underage Drinking, Adolescent, Adult, Anxiety, Child, Child, Preschool, Depression, Female, Humans, Infant, Longitudinal Studies, Male, Mental Health, Prospective Studies, Substance-Related Disorders, Adult Survivors of Child Abuse
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