The DOI matches its Crossref record; 311 of the 311 references it cites were found in a registry or an index.
Mating-Type Genes and MAT Switching in Saccharomyces cerevisiae
Open accessAbstract
Mating type in Saccharomyces cerevisiae is determined by two nonhomologous alleles, MATa and MATα. These sequences encode regulators of the two different haploid mating types and of the diploids formed by their conjugation. Analysis of the MATa1, MATα1, and MATα2 alleles provided one of the earliest models of cell-type specification by transcriptional activators and repressors. Remarkably, homothallic yeast cells can switch their mating type as often as every generation by a highly choreographed, site-specific homologous recombination event that replaces one MAT allele with different DNA sequences encoding the opposite MAT allele. This replacement process involves the participation of two intact but unexpressed copies of mating-type information at the heterochromatic loci, HMLα and HMRa, which are located at opposite ends of the same chromosome-encoding MAT. The study of MAT switching has yielded important insights into the control of cell lineage, the silencing of gene expression, the formation of heterochromatin, and the regulation of accessibility of the donor sequences. Real-time analysis of MAT switching has provided the most detailed description of the molecular events that occur during the homologous recombinational repair of a programmed double-strand chromosome break.
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Cites
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
Imai, S.-I., Armstrong, C. M., Kaeberlein, M., & Guarente, L. (2000) · Nature · doi:10.1038/35001622 · Cited by 3,510
Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae
Pâques, F., & Haber, J. E. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.2.349-404.1999 · Cited by 2,120
Self-citationMechanism of Eukaryotic Homologous Recombination
San Filippo, J., Sung, P., & Klein, H. (2008) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.061306.125255 · Cited by 1,681
Genetic and Functional Diversification of Small RNA Pathways in Plants
Xie, Z., Johansen, L. K., Gustafson, A. M., Kasschau, K. D., Lellis, A. D., Zilberman, D., Jacobsen, S. E., & Carrington, J. C. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020104 · Cited by 1,584
Extrachromosomal rDNA circles—a cause of aging in yeast
Sinclair, D. A., & Guarente, L. (1997) · Cell · doi:10.1016/s0092-8674(00)80493-6 · Cited by 1,500
The Sir2 Family of Protein Deacetylases
Blander, G., & Guarente, L. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073651 · Cited by 1,495
Homologous recombination in DNA repair and DNA damage tolerance
Li, X., & Heyer, W.-D. (2008) · Cell Research · doi:10.1038/cr.2008.1 · Cited by 1,197
Regulation of Homologous Recombination in Eukaryotes
Heyer, W.-D., Ehmsen, K. T., & Liu, J. (2010) · Annual Review of Genetics · doi:10.1146/annurev-genet-051710-150955 · Cited by 1,066
Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends
Zhu, Z., Chung, W.-H., Shim, E. Y., Lee, S. E., & Ira, G. (2008) · Cell · doi:10.1016/j.cell.2008.08.037 · Cited by 1,051
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Cannan, W. J., & Pederson, D. S. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25048 · Cited by 499
“…occurs during the development of somatic nuclei in protozoans (reviewed in Duharcourt et al., 2009), mating-type switching in yeast (reviewed in Haber, 2012), T-cell receptor formation in T-lymphocytes, and immunoglobulin class switching in B-lymphocytes (reviewed in Soulas-Sprauel et al.,…”
BackgroundComplete genome sequence and comparative genomics of the probiotic yeast Saccharomyces boulardii
Khatri, I., Tomar, R., Ganesan, K., Prasad, G. S., & Subramanian, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-00414-2 · Cited by 123
Efficient mating-type switching in Candida glabrata induces cell death
Boisnard, S., Zhou Li, Y., Arnaise, S., Sequeira, G., Raffoux, X., Enache-Angoulvant, A., Bolotin-Fukuhara, M., & Fairhead, C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0140990 · Cited by 29
Use of Haploid Model of Candida albicans to Uncover Mechanism of Action of a Novel Antifungal Agent
Truong, T., Suriyanarayanan, T., Zeng, G., Le, T. D., Liu, L., Li, J., Tong, C., Wang, Y., & Seneviratne, C. J. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00164 · Cited by 16
Metadata
- Authors
- Haber, J. E.
- Venue
- Genetics
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-05-01
- Volume
- 191
- Issue
- 1
- Pages
- 33-64
- ISSN
- 0016-6731 (ISSN-L)
- 1943-2631
- OpenAlex
- W2029895295
- Cited by
- 425
- References
- 311
- FWCI
- 13.48
- Type
- journal article
- Language
- en
- Open access
- bronze
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