CoChat
Sign Up
Cited by 191Autism Spectrum Disorder ResearchChild Nutrition and Feeding IssuesAttention Deficit Hyperactivity Disorder

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Use of Psychotropic Medication in Children and Adolescents With Autism Spectrum Disorders

Coury, Daniel L., Anagnostou, Evdokia, Manning-Courtney, Patricia, Reynolds, Ann, Cole, Lynn, McCoy, Robin, Whitaker, Agnes, Perrin, James M.·2012·PEDIATRICS
DOI 10.1542/peds.2012-0900d
Open this paper in CoChat — free account

Abstract

OBJECTIVES: The goal of this study was to examine rates of psychotropic medication use and identify associated child and family characteristics among children and adolescents with autism spectrum disorder (ASD) enrolled in an autism registry maintained by the Autism Treatment Network (ATN). METHODS: The sample, derived from the ATN registry, consists of 2853 children aged 2 to 17 years with diagnoses of ASD supported by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and the Autism Diagnostic Observation Schedule with available data on medication use. As part of initial enrollment in the registry, parents completed questionnaires on current psychotropic medication use, psychiatric and medical conditions, and demographics. RESULTS: Of the 2853 children, 763 (27%) were taking ≥ 1 psychotropic medication; 15% were prescribed 1 medication, 7.4% received 2 medications, and 4.5% received ≥ 3. Among children aged 3 to 5 years, 11% were taking ≥ 1 psychotropic medication; among 6- to 11-year-old children, 46%; and 66% of adolescents aged 12 to 17 years were taking at ≥ 1 psychotropic medication. A parent report of comorbid diagnosis of attention-deficit/hyperactivity disorder, bipolar disorder, obsessive-compulsive disorder, depression, or anxiety was associated with a high rate of use, with 80% receiving ≥ 1 psychotropic medication. Only 15% of children with no comorbid psychiatric disorder were taking psychotropic medication. Psychotropic medication use was also related to sleep and gastrointestinal problems. CONCLUSIONS: The prescription of psychotropic medications in this registry sample is highly related to comorbid psychiatric disorder. Other factors associated with use include medical comorbidities, race, ethnicity, and older age.

Overview

Integrity signals

Registry

Crossref · 10.1542/peds.2012-0900d

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 32 references

Research works printed but not linked: 1

  1. McDougle, 2008, Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders, J Clin Psychiatry., 69, 15

Cited by

Sorted by citations

See all 191

Related

Metadata

Authors
Coury, D. L., Anagnostou, E., Manning-Courtney, P., Reynolds, A., Cole, L., McCoy, R., Whitaker, A., & Perrin, J. M.
Affiliations
  • Nationwide Children's Hospital (US)
  • University of Toronto (CA)
  • Department of Pediatrics, University of Cincinnati College of Medicine, and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio;
  • University of Colorado Denver (US)
  • University of Rochester Medicine (US)
  • Oregon Health & Science University (US)
  • Columbia University (US)
  • Harvard University (US)
Corresponding author
Coury, Daniel L.
ORCID
Venue
PEDIATRICS
Publisher
American Academy of Pediatrics (AAP)
Published
2012-11-01
Volume
130
Issue
Supplement_2
Pages
S69-S76
ISSN
  • 0031-4005 (ISSN-L)
  • 1098-4275
DOI
10.1542/peds.2012-0900d
OpenAlex
W2134810756
Cited by
191
References
32
Citations by year
2026: 4 · 2025: 11 · 2024: 15 · 2023: 7 · 2022: 20 · 2021: 13 · 2020: 14 · 2019: 11 · 2018: 16 · 2017: 15 · 2016: 17 · 2015: 19 · 2014: 18 · 2013: 11
FWCI
7.84
Type
journal article
Language
en
Open access
closed
Locations
  • PEDIATRICS (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
Keywords
psychotropic drugs, autism spectrum disorder, children and adolescents, psychiatric comorbidity, attention deficit hyperactivity disorder, bipolar disorder, obsessive-compulsive disorder, depression, anxiety, sleep disorders, gastrointestinal problems
MeSH terms
Adolescent, Child, Child Development Disorders, Pervasive, Child, Preschool, Female, Humans, Male, Psychotropic Drugs

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review