The DOI matches its Crossref record; 86 of the 87 references it cites were found in a registry or an index.
Cognitive-Behavioral Therapy for Anxiety in Children With High-Functioning Autism: A Meta-analysis
Open accessAbstract
BACKGROUND: Anxiety is a common and impairing problem in children and adolescents with autism spectrum disorder (ASD). There is emerging evidence that cognitive-behavioral therapy (CBT) could reduce anxiety in children with high-functioning ASD. OBJECTIVE: To systematically review the evidence of using CBT to treat anxiety in children and adolescents with ASD. Methods for this review were registered with PROSPERO (CRD42012002722). METHODS: We included randomized controlled trials published in English in peer-reviewed journals comparing CBT with another treatment, no treatment control, or waitlist control. Two authors independently screened 396 records obtained from database searches and hand searched relevant journals. Two authors independently extracted and reconciled all data used in analyses from study reports. RESULTS: Eight studies involving 469 participants (252 treatment, 217 comparison) met our inclusion criteria and were included in meta-analyses. Overall effect sizes for clinician- and parent-rated outcome measures of anxiety across all studies were d = 1.19 and d = 1.21, respectively. Five studies that included child self-report yielded an average d = 0.68 across self-reported anxiety. CONCLUSIONS: Parent ratings and clinician ratings of anxiety are sensitive to detecting treatment change with CBT for anxiety relative to waitlist and treatment-as-usual control conditions in children with high-functioning ASD. Clinical studies are needed to evaluate CBT for anxiety against attention control conditions in samples of children with ASD that are well characterized with regard to ASD diagnosis and co-occurring anxiety symptoms.
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“Adapted CBT interventions, group and individual, have been shown to be clinically effective for ameliorating anxiety in children and young people and adults. 35,36”
From Guided self-help for depression in autistic adults: The ADEPT feasibility RCT (2019) · cites this paper as [35]
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“animal models of social behavior, including the mice used here, do not fully recapitulate the complexity and natural process in which humans interact, or capture the wide spectrum of behavioral phenotypes that are affected by ASD 14,48,49.”
From Reduced sociability and social agency encoding in adult Shank3-mutant mice are restored through gene re-expression in real time (2021) · cites this paper as [48]
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Metadata
- Authors
- Sukhodolsky, D. G., Bloch, M. H., Panza, K. E., & Reichow, B.
- Affiliations
- Yale University (US)
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2013-10-28
- Volume
- 132
- Issue
- 5
- Pages
- e1341-e1350
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- PMC
- PMC3813396
- OpenAlex
- W2110855627
- Cited by
- 234
- References
- 87
- Citations by year
- 2026: 8 · 2025: 11 · 2024: 16 · 2023: 18 · 2022: 17 · 2021: 27 · 2020: 31 · 2019: 21 · 2018: 22 · 2017: 27 · 2016: 16 · 2015: 14 · 2014: 5 · 2013: 1
- FWCI
- 6.56
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- PEDIATRICS (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (K01MH079130, K23MH091240, R25MH077823)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD083881)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- cognitive behavioral therapy, anxiety, high-functioning autism, autism spectrum disorder, children, adolescents, treatment efficacy, child self-report, waitlist control
- MeSH terms
- Anxiety, Autistic Disorder, Child, Humans, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic
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