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Prenatal SSRI Use and Offspring With Autism Spectrum Disorder or Developmental Delay
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OBJECTIVE: To examine associations between prenatal use of selective serotonin reuptake inhibitors (SSRIs) and the odds of autism spectrum disorders (ASDs) and other developmental delays (DDs). METHODS: A total of 966 mother-child pairs were evaluated (492 ASD, 154 DD, 320 typical development [TD]) from the Childhood Autism Risks from Genetics and the Environment (CHARGE) Study, a population-based case-control study. Standardized measures confirmed developmental status. Interviews with biological mothers ascertained prenatal SSRI use, maternal mental health history, and sociodemographic information. RESULTS: Overall, prevalence of prenatal SSRI exposure was lowest in TD children (3.4%) but did not differ significantly from ASD (5.9%) or DD (5.2%) children. Among boys, prenatal SSRI exposure was nearly 3 times as likely in children with ASD relative to TD (adjusted odds ratio [OR]: 2.91; 95% confidence interval [CI]: 1.07–7.93); the strongest association occurred with first-trimester exposure (OR: 3.22; 95% CI: 1.17–8.84). Exposure was also elevated among boys with DD (OR: 3.39; 95% CI: 0.98–11.75) and was strongest in the third trimester (OR: 4.98; 95% CI: 1.20–20.62). Findings were similar among mothers with an anxiety or mood disorder history. CONCLUSIONS: In boys, prenatal exposure to SSRIs may increase susceptibility to ASD or DD. Findings from published studies on SSRIs and ASD continues to be inconsistent. Potential recall bias and residual confounding by indication are concerns. Larger samples are needed to replicate DD results. Because maternal depression itself carries risks for the fetus, the benefits of prenatal SSRI use should be carefully weighed against potential harms.
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“Relationships between DD and prenatal SSRIs were overall similar to those observed with ASD, and in agreement with previous null reports of prenatal SSRI use and ADHD (21, 25, 42), DD (32, 57), and ID (27, 58).”
From Maternal Psychiatric Conditions, Treatment With Selective Serotonin Reuptake Inhibitors, and Neurodevelopmental Disorders (2021) · cites this paper as [32]
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“These positive findings in other studies persisted even after efforts to reduce confounding by indication through adjustment for maternal psychiatric condition (29, 31, 43, 44), restriction to mothers with psychiatric conditions (27–30, 32), and propensity weighting methods (30).”
From Maternal Psychiatric Conditions, Treatment With Selective Serotonin Reuptake Inhibitors, and Neurodevelopmental Disorders (2021) · cites this paper as [32]
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“Previous studies have observed associations between prenatal SSRI exposure and specific types of DD, including motor (32, 59) and speech/language delays (57).”
From Maternal Psychiatric Conditions, Treatment With Selective Serotonin Reuptake Inhibitors, and Neurodevelopmental Disorders (2021) · cites this paper as [32]
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“However, reflecting the mixed evidence of this research area, our findings also contradict several other large studies conducted in Sweden,(30, 43) the Netherlands (44), California (31, 32), Canada (29), and Denmark (27, 28).”
From Maternal Psychiatric Conditions, Treatment With Selective Serotonin Reuptake Inhibitors, and Neurodevelopmental Disorders (2021) · cites this paper as [32]
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“For ASD as the outcome, seven case–control studies (involving 291,468 patients and 13,243 cases of ASD) [17, 18, 26–29, 32] and eight cohort studies (involving 3,294,218 patients and 27,342 cases of ASD) [16, 19, 25, 30, 31, 33–35] were included.”
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“there was a total of 15 observational studies measuring ASD as an outcome [16–19, 25–35].”
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Citations
Cites
The Measurement of Observer Agreement for Categorical Data
Landis, J. R., & Koch, G. G. (1977) · Biometrics · doi:10.2307/2529310 · Cited by 81,148
Mullen Scales of Early Learning
Bradley‐Johnson, S. (1997) · Psychology in the Schools · doi:10.1002/(sici)1520-6807(199710)34:4 · Cited by 2,329
Social Communication Questionnaire
Lund, E. M. (2014) · Encyclopedia of Special Education · doi:10.1002/9781118660584.ese2224 · Cited by 975
Autism Diagnostic Observation Schedule
Kim, S. H., & Lord, C. (2017) · Springer eBooks · doi:10.1007/978-3-319-56782-2_1520-2 · Cited by 782
A transient placental source of serotonin for the fetal forebrain
Bonnin, A., Goeden, N., Chen, K., Wilson, M. L., King, J., Shih, J. C., Blakely, R. D., Deneris, E. S., & Levitt, P. (2011) · Nature · doi:10.1038/nature09972 · Cited by 608
Combining Information From Multiple Sources in the Diagnosis of Autism Spectrum Disorders
RISI, S., LORD, C., GOTHAM, K., CORSELLO, C., CHRYSLER, C., SZATMARI, P., COOK, E. H., LEVENTHAL, B. L., & PICKLES, A. (2006) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000227880.42780.0e · Cited by 581
Perinatal Risks of Untreated Depression during Pregnancy
Bonari, L., Pinto, N., Ahn, E., Einarson, A., Steiner, M. S., & Koren, G. (2004) · The Canadian Journal of Psychiatry · doi:10.1177/070674370404901103 · Cited by 534
Antidepressant Use During Pregnancy and Childhood Autism Spectrum Disorders
Croen, L. A. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.73 · Cited by 510
Research works printed but not linked: 2
- Sparrow, 1984, Vineland Adaptive Behavior Scales Interview Edition Expanded Form
- Rothman, 2008, Validity in epidemiologic studies, 128
Cited by
Sorted by citations
The Female Autism Phenotype and Camouflaging: a Narrative Review
Hull, L., Petrides, K. V., & Mandy, W. (2020) · Review Journal of Autism and Developmental Disorders · doi:10.1007/s40489-020-00197-9 · Cited by 614
The serotonin system in autism spectrum disorder: From biomarker to animal models
Muller, C. L., Anacker, A. M. J., & Veenstra-VanderWeele, J. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.11.010 · Cited by 531
Brummelte, S., Mc Glanaghy, E., Bonnin, A., & Oberlander, T. F. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2016.02.037 · Cited by 306
Preeclampsia, Placental Insufficiency, and Autism Spectrum Disorder or Developmental Delay
Walker, C. K., Krakowiak, P., Baker, A., Hansen, R. L., Ozonoff, S., & Hertz-Picciotto, I. (2015) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2014.2645 · Cited by 292
Self-citationMandy, W., & Lai, M. (2016) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12501 · Cited by 283
Depression during pregnancy and postpartum
Becker, M., Weinberger, T., Chandy, A., & Schmukler, S. (2016) · Current Psychiatry Reports · doi:10.1007/s11920-016-0664-7 · Cited by 263
Environmental factors influencing the risk of autism
Karimi, P., Kamali, E., Mousavi, S. M., & Karahmadi, M. (2017) · Journal of Research in Medical Sciences · doi:10.4103/1735-1995.200272 · Cited by 289
Prenatal factors associated with autism spectrum disorder (ASD)
Ornoy, A., Weinstein-Fudim, L., & Ergaz, Z. (2015) · Reproductive Toxicology · doi:10.1016/j.reprotox.2015.05.007 · Cited by 238
Sujan, A. C., Rickert, M. E., Öberg, A. S., Quinn, P. D., Hernández-Díaz, S., Almqvist, C., Lichtenstein, P., Larsson, H., & D’Onofrio, B. M. (2017) · JAMA · doi:10.1001/jama.2017.3413 · Cited by 226
The Utility of Zebrafish as a Model for Screening Developmental Neurotoxicity
d’Amora, M., & Giordani, S. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00976 · Cited by 240
Understanding environmental contributions to autism: Causal concepts and the state of science
Hertz‐Picciotto, I., Schmidt, R. J., & Krakowiak, P. (2018) · Autism Research · doi:10.1002/aur.1938 · Cited by 198
Self-citationBrown, H. K., Ray, J. G., Wilton, A. S., Lunsky, Y., Gomes, T., & Vigod, S. N. (2017) · JAMA · doi:10.1001/jama.2017.3415 · Cited by 143
Pearlstein, T. B. (2015) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2015.04.004 · Cited by 149
Perinatal Generalized Anxiety Disorder: Assessment and Treatment
Misri, S. K., Abizadeh, J., Sanders, S., & Swift, E. (2015) · Journal of Women s Health · doi:10.1089/jwh.2014.5150 · Cited by 165
Ornoy, A., Weinstein‐Fudim, L., & Ergaz, Z. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00316 · Cited by 141
Morales, D. R., Slattery, J., Evans, S., & Kurz, X. (2018) · BMC Medicine · doi:10.1186/s12916-017-0993-3 · Cited by 118
Man, K. K. C., Tong, H. H. Y., Wong, L. Y. L., Chan, E. W., Simonoff, E., & Wong, I. C. K. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.11.020 · Cited by 126
Carter, C., & Blizard, R. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.10.011 · Cited by 116
Prenatal environmental risk factors for autism spectrum disorder and their potential mechanisms
Love, C., Sominsky, L., O’Hely, M., Berk, M., Vuillermin, P., & Dawson, S. L. (2024) · BMC Medicine · doi:10.1186/s12916-024-03617-3 · Cited by 110
Mezzacappa, A., Lasica, P.-A., Gianfagna, F., Cazas, O., Hardy, P., Falissard, B., Sutter-Dallay, A.-L., & Gressier, F. (2017) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2017.0124 · Cited by 108
Vigod, S. N., Wilson, C. A., & Howard, L. M. (2016) · BMJ · doi:10.1136/bmj.i1547 · Cited by 148
Glover, M. E., & Clinton, S. M. (2016) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2016.04.008 · Cited by 109
Paroxetine—The Antidepressant from Hell? Probably Not, But Caution Required
Nevels, R. M., Gontkovsky, S. T., & Williams, B. E. (2025) · Psychopharmacology Bulletin · doi:10.64719/pb.4345 · Cited by 95
Salari, A., Fatehi-Gharehlar, L., Motayagheni, N., & Homberg, J. R. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.05.062 · Cited by 97
Antidepressants during pregnancy and autism in offspring: population based cohort study
Rai, D., Lee, B. K., Dalman, C., Newschaffer, C., Lewis, G., & Magnusson, C. (2017) · BMJ · doi:10.1136/bmj.j2811 · Cited by 93
El Marroun, H., White, T., Verhulst, F. C., & Tiemeier, H. (2014) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-014-0558-3 · Cited by 92
Association of Sex With Recurrence of Autism Spectrum Disorder Among Siblings
Palmer, N., Beam, A., Agniel, D., Eran, A., Manrai, A., Spettell, C., Steinberg, G., Mandl, K., Fox, K., Nelson, S. F., et al. (2017) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2017.2832 · Cited by 89
Davis, E. P., Hankin, B. L., Swales, D. A., & Hoffman, M. C. (2018) · Development and Psychopathology · doi:10.1017/s0954579418000470 · Cited by 95
Andalib, S., Emamhadi, M. R., Yousefzadeh-Chabok, S., Shakouri, S. K., Høilund-Carlsen, P. F., Vafaee, M. S., & Michel, T. M. (2017) · European Psychiatry · doi:10.1016/j.eurpsy.2017.06.001 · Cited by 86
Garbarino, V. R., Gilman, T. L., Daws, L. C., & Gould, G. G. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.07.010 · Cited by 85
Millard, S. J., Weston–Green, K., & Newell, K. A. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.06.008 · Cited by 83
Kobayashi, T., Matsuyama, T., Takeuchi, M., & Ito, S. (2016) · Reproductive Toxicology · doi:10.1016/j.reprotox.2016.07.016 · Cited by 86
Beversdorf, D. Q., & MISSOURI AUTISM SUMMIT CONSORTIUM* (2016) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/dbp.0000000000000351 · Cited by 74
Prenatal antidepressant exposure associated withCYP2E1DNA methylation change in neonates
Gurnot, C., Martin-Subero, I., Mah, S. M., Weikum, W., Goodman, S. J., Brain, U. M., Werker, J. F., Kobor, M. S., Esteller, M., Oberlander, T. F., et al. (2015) · Epigenetics · doi:10.1080/15592294.2015.1026031 · Cited by 74
Protective Effect or Missed Diagnosis? Females with Autism Spectrum Disorder
Hull, L., & Mandy, W. (2017) · Future Neurology · doi:10.2217/fnl-2017-0006 · Cited by 80
Safety of Selective Serotonin Reuptake Inhibitors in Pregnancy: A Review of Current Evidence
Alwan, S. S., Friedman, J. M., & Chambers, C. (2016) · CNS Drugs · doi:10.1007/s40263-016-0338-3 · Cited by 80
Gentile, S. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.04.048 · Cited by 70
Jha, S. C., Meltzer-Brody, S., Steiner, R. J., Cornea, E., Woolson, S., Ahn, M., Verde, A. R., Hamer, R. M., Zhu, H., Styner, M., et al. (2016) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2016.05.004 · Cited by 66
Kaplan, Y. C., Arslan, E. K., Acar, S., & Sözmen, K. (2016) · Reproductive Toxicology · doi:10.1016/j.reprotox.2016.09.013 · Cited by 69
Autism risk following antidepressant medication during pregnancy
Viktorin, A., Uher, R., Reichenberg, A., Levine, S. Z., & Sandin, S. (2017) · Psychological Medicine · doi:10.1017/s0033291717001301 · Cited by 62
Lebin, L. G., & Novick, A. M. (2022) · Current Psychiatry Reports · doi:10.1007/s11920-022-01372-x · Cited by 87
Hagberg, K. W., Robijn, A. L., & Jick, S. S. (2018) · Clinical Epidemiology · doi:10.2147/clep.s180618 · Cited by 60
Improving autism perinatal risk factors: A systematic review
Cheng, J. X., Eskenazi, B., Widjaja, F., Cordero, J. F., & Hendren, R. L. (2019) · Medical Hypotheses · doi:10.1016/j.mehy.2019.03.012 · Cited by 64
Rommel, A., Bergink, V., Liu, X., Munk‐Olsen, T., & Molenaar, N. M. (2020) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.19r12965 · Cited by 61
Sprowles, J. L. N., Wendel, J. R. H., Gutierrez, A., Bailey, R. A., Jablonski, S. A., Williams, M. T., & Vorhees, C. V. (2016) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2016.08.007 · Cited by 62
Autism spectrum disorder: Trends in research exploring etiopathogenesis
Gyawali, S., & Patra, B. N. (2019) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12860 · Cited by 59
Ornoy, A., & Koren, G. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20102370 · Cited by 54
Barkoski, J. M., Busgang, S. A., Bixby, M., Bennett, D. H., Schmidt, R. J., Barr, D. B., Panuwet, P., Gennings, C., & Hertz‐Picciotto, I. (2019) · Environmental Research · doi:10.1016/j.envres.2019.108719 · Cited by 55
Self-citationThe posterity of Zebrafish in paradigm of in vivo molecular toxicological profiling
Verma, S. K., Nandi, A., Sinha, A., Patel, P., Mohanty, S., Jha, E., Jena, S., Kumari, P., Ghosh, A., Jerman, I., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116160 · Cited by 56
Sujan, A. C., Öberg, A. S., Quinn, P. D., & D'Onofrio, B. M. (2018) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13004 · Cited by 55
Lee, J., & Freeman, J. L. (2014) · Toxics · doi:10.3390/toxics2030464 · Cited by 54
Viktorin, A., Uher, R., Kolevzon, A., Reichenberg, A., Levine, S. Z., & Sandin, S. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.1727 · Cited by 45
Kaplan, Y. C., Arslan, E. K., Acar, S., & Sözmen, K. (2017) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.13382 · Cited by 53
Variations in Neurodevelopmental Outcomes in Children with Prenatal SSRI Antidepressant Exposure
Rotem‐Kohavi, N., & Oberlander, T. F. (2017) · Birth Defects Research · doi:10.1002/bdr2.1076 · Cited by 51
Leshem, R., Bar‐Oz, B., Diav‐Citrin, O., Gbaly, S., Soliman, J., Renoux, C., & Matok, I. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210303121059 · Cited by 54
Ayano, G., Maravilla, J. C., & Alati, R. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.01.038 · Cited by 46
Autism spectrum disorders: let’s talk about glucose?
Hoirisch-Clapauch, S., & Nardi, A. E. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0370-4 · Cited by 44
Muzik, M., & Hamilton, S. E. (2016) · Maternal and Child Health Journal · doi:10.1007/s10995-016-2038-5 · Cited by 47
Horackova, H., Karahoda, R., Červený, L., Váchalová, V., Ebner, R., Abad, C., & Štaud, F. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13081306 · Cited by 40
Sciara, A., Beasley, B., Crawford, J. D., Anderson, E. P., Carrasco, T., Zheng, S., Ordway, G. A., & Chandley, M. (2020) · Autism Research · doi:10.1002/aur.2284 · Cited by 42
Hjorth, S., Bromley, R., Ystrøm, E., Lupattelli, A., Spigset, O., & Nordeng, H. (2019) · PLoS ONE · doi:10.1371/journal.pone.0219778 · Cited by 40
Marroun, H. E., White, T. J. H., Fernández, G., Jaddoe, V. W. V., Verhulst, F. C., Stricker, B. H. C., & Tiemeier, H. W. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116665335 · Cited by 39
Gemmel, M., Lacalle, S. D., Mort, S. C., Hill, L. A., Charlier, T. D., & Pawluski, J. L. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.10.009 · Cited by 42
Ames, J. L., Ladd-Acosta, C., Fallin, M. D., Qian, Y., Schieve, L. A., DiGuiseppi, C., Lee, L.-C., Kasten, E. P., Zhou, G., Pinto-Martin, J., et al. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.04.002 · Cited by 36
Self-citationPreschool Outcomes Following Prenatal Serotonin Reuptake Inhibitor Exposure
Johnson, K. C., Smith, A. K., Stowe, Z. N., Newport, D. J., & Brennan, P. A. (2016) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.14m09348 · Cited by 36
Perinatal reduction of functional serotonin transporters results in developmental delay
Kroeze, Y., Dirven, B. C. J., Janssen, S., Kröhnke, M., Barte, R. M., Middelman, A., van Bokhoven, H., Zhou, H., & Homberg, J. R. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.05.012 · Cited by 36
Zhou, X., Li, Y., Ou, J.-J., & Li, Y. (2018) · Molecular Autism · doi:10.1186/s13229-018-0207-7 · Cited by 38
Controversies About the Use of Antidepressants in Pregnancy
Robinson, G. E. (2015) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000256 · Cited by 34
Selective serotonin reuptake inhibitors for depression in pregnancy
Susser, L. C., Sansone, S. A., & Hermann, A. D. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2016.07.011 · Cited by 35
Sprowles, J. L. N., Wendel, J. R. H., Gutierrez, A., Bailey, R. A., Jablonski, S. A., Williams, M. T., & Vorhees, C. V. (2017) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2017.06.004 · Cited by 33
Adjimann, T. S., Argañaraz, C., & Soiza‐Reilly, M. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01388-6 · Cited by 34
Podrebarac, S. K., Duerden, E. G., Chau, V., GRUNAU, R. E., Synnes, A. R., Oberlander, T. F., & Miller, S. P. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.11.025 · Cited by 31
Halvorsen, A., Hesel, B., Østergaard, S. D., & Danielsen, A. A. (2019) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13030 · Cited by 31
Prenatal Antidepressant Exposure and Child Motor Development: A Meta-analysis
Grove, K., Lewis, A. J., & Galbally, M. (2018) · PEDIATRICS · doi:10.1542/peds.2018-0356 · Cited by 29
Memantine rescues prenatal citalopram exposure-induced striatal and social abnormalities in mice
Zahra, A., Jiang, J., Chen, Y., Long, C., & Yang, L. (2018) · Experimental Neurology · doi:10.1016/j.expneurol.2018.06.003 · Cited by 28
Vega, M. L., Newport, G. C., Bozhdaraj, D., Saltz, S. B., Nemeroff, C. B., & Newport, D. J. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.18070766 · Cited by 30
Exercise and yoga during pregnancy and their impact on depression: a systematic literature review
Jarbou, N. S., & Newell, K. A. (2022) · Archives of Women s Mental Health · doi:10.1007/s00737-021-01189-2 · Cited by 33
Araújo, J. N. D. M., Delgado, I. F., & Paumgartten, F. J. R. (2020) · Cadernos de Saúde Pública · doi:10.1590/0102-311x00026619 · Cited by 32
Ram, S., Howland, M. A., Sandman, C. A., Davis, E. P., & Glynn, L. M. (2018) · Clinical Psychological Science · doi:10.1177/2167702618811079 · Cited by 28
Zhou, X., Lu, J. Y.-F., Darling, R. D., Simpson, K. L., Zhu, X., Wang, F., Yu, L., Sun, X., Merzenich, M. M., & Lin, R. C. S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1416582111 · Cited by 26
Damkier, P., Pottegård, A., Christensen, R. D., & Hallas, J. (2014) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12322 · Cited by 26
Is there sexual dimorphism of hyperserotonemia in autism spectrum disorder?
Shuffrey, L. C., Guter, S. J., Delaney, S., Jacob, S., Anderson, G. M., Sutcliffe, J. S., Cook, E. H., & Veenstra-VanderWeele, J. M. (2017) · Autism Research · doi:10.1002/aur.1791 · Cited by 25
Healy, D., Noury, J. C. L., & Mangin, D. A. (2016) · International Journal of Risk & Safety in Medicine · doi:10.3233/jrs-160726 · Cited by 24
Meyer, L. R., Dexter, B. C., Lo, C., Kenkel, E. J., Hirai, T., Roghair, R. D., & Haskell, S. E. (2017) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2017.1317342 · Cited by 26
Bond, C. M., Johnson, J. C., Chaudhary, V., McCarthy, E. M., McWhorter, M. L., & Woehrle, N. S. (2019) · Brain Research · doi:10.1016/j.brainres.2019.06.001 · Cited by 27
The microbiome as a modulator of neurological health across the maternal-offspring interface
Orchanian, S. B., & Hsiao, E. Y. (2025) · Journal of Clinical Investigation · doi:10.1172/jci184314 · Cited by 23
Bastaki, K., Alwan, S. S., & Zahir, F. (2020) · Advances in neurobiology · doi:10.1007/978-3-030-30402-7_5 · Cited by 21
Yarger, H. A., & Redcay, E. (2020) · Development and Psychopathology · doi:10.1017/s095457942000084x · Cited by 23
Jajoo, A. N., Donlon, C., Shnayder, S., Levin, M. G., & McVey, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-61362-y · Cited by 20
Vuong, H. E., Coley, E. J. L., Kazantsev, M., Cooke, M. E., Rendon, T. K., Paramo, J., & Hsiao, E. Y. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113353 · Cited by 19
Prenatal antidepressant exposure and sex differences in neonatal corpus callosum microstructure
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Tate, K. M., Kirk, B., Tseng, A., Ulffers, A. E., & Litwa, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910457 · Cited by 20
Edwards, K. A., Madden, A. M. K., & Zup, S. L. (2018) · Brain Research · doi:10.1016/j.brainres.2018.07.020 · Cited by 19
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Metadata
- Authors
- Harrington, R. A., Lee, L.-C., Crum, R. M., Zimmerman, A. W., & Hertz-Picciotto, I.
- Affiliations
- Johns Hopkins University (US)
- University of Massachusetts Chan Medical School (US)
- Department of Public Health Sciences and the MIND Institute, University of California, Davis, Davis, California
- ORCID
- Zimmerman, Andrew W.
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2014-05-01
- Volume
- 133
- Issue
- 5
- Pages
- e1241-e1248
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- PMC
- PMC4006441
- OpenAlex
- W2105930613
- Cited by
- 174
- References
- 50
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 6 · 2023: 3 · 2022: 6 · 2021: 13 · 2020: 17 · 2019: 15 · 2018: 21 · 2017: 25 · 2016: 34 · 2015: 16 · 2014: 7
- FWCI
- 26.85
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- PEDIATRICS (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Autism Speaks
- National Institutes of Health (ES11269)
- National Institute of Environmental Health Sciences (R01ES015359, P01ES011269)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy and Medication Impact
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Keywords
- prenatal SSRI exposure, selective serotonin reuptake inhibitors, autism spectrum disorder, developmental delay, maternal mental health, maternal depression, first trimester exposure, third trimester exposure, sex differences, CHARGE study, maternal medication use
- MeSH terms
- California, Developmental Disabilities, Child Development Disorders, Pervasive, Child, Preschool, Drug Utilization, Female, Humans, Male, Pregnancy, Pregnancy Trimester, First, Pregnancy Trimester, Third, Prenatal Exposure Delayed Effects, Sex Factors, Odds Ratio, Case-Control Studies
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