Autistic and dysphasic children. II: epilepsy.
Abstract
In a previously described population of 314 autistic and 237 dysphasic nonautistic children, after exclusion of 12 autistic girls with Rett syndrome, 14% (42 of 302) of autistic children and 8% (19 of 237) of dysphasic children had epilepsy (P = .03). The major risk factors for epilepsy were severe mental deficiency and the combination of severe mental deficiency with a motor deficit. In autistic children without severe mental deficiency, motor deficit, associated perinatal or medical disorder, or a positive family history of epilepsy, epilepsy occurred in 6% (10 of 160) which was analogous to the 8% (14 of 168) found in similar dysphasic nonautistic children. The language subtype of verbal auditory agnosia is associated with the highest risk of epilepsy in autistic (41%, 7 of 17) and dysphasic (58%, 7 of 12) children. The higher percentage of epilepsy in autistic girls, 24% (18 of 74) compared with boys 11% (25 of 228) (P = .003), is attributed to the increased prevalence of cognitive and motor deficit in girls. Once the risk attributable to associated cognitive and motor disabilities is taken into account, there is no difference in the risk of epilepsy between autistic and nonautistic dysphasic children.
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Frequently encountered medical factors in ASD include seizures (particularly in children with severe intellectual disability, motor deficits, or a positive family history of epilepsy), other gastrointestinal symptoms, and sleep disturbances affecting daytime functioning.
“Frequently encountered medical factors in ASD include: seizures, particularly in children who also have severe intellectual disability, motor deficits, or a positive family history of epilepsy 68 , 69 ; other gastrointestinal symptoms 57 , 70 ; and sleep disturbances affecting daytime functioning.”
From Early Intervention for Children With Autism Spectrum Disorder Under 3 Years of Age: Recommendations for Practice and Research (2015) · cites this paper as [69]
Cites
Comparative Study of 5% Permethrin Cream and 1% Lindane Lotion for the Treatment of Scabies
Schultz, M. W. (1990) · Archives of Dermatology · doi:10.1001/archderm.1990.01670260037006 · Cited by 123 · see citing works
Kopf, A. W., Kripke, M. L., & Stern, R. S. (1984) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(84)70225-8 · Cited by 103 · see citing works
1% Permethrin Cream Rinse vs 1% Lindane Shampoo in Treating Pediculosis Capitis
Brandenburg, K. (1986) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1986.02140230064034 · Cited by 65 · see citing works
Krowchuk, D. P., Tunnessen, W. W., & Hurwitz, S. (1992) · PEDIATRICS · doi:10.1542/peds.90.2.259 · Cited by 10 · see citing works
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Epidemiological Surveys of Autism and Other Pervasive Developmental Disorders: An Update
Fombonne, E. (2003) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1025054610557 · Cited by 1,505 · see citing works
Management of Children With Autism Spectrum Disorders
Myers, S. M., Johnson, C. P., & the Council on Children With Disabilities (2007) · Pediatrics · doi:10.1542/peds.2007-2362 · Cited by 1,125 · see citing works
Practice parameter: Screening and diagnosis of autism
Filipek, P. A., Accardo, P., Ashwal, S., Baranek, G. T., Cook, E. H., Dawson, G., Gordon, B., Gravel, J. S., Johnson, C. P., Kallen, R. J., et al. (2000) · Neurology · doi:10.1212/wnl.55.4.468 · Cited by 1,061 · see citing works
Self-citationThe Screening and Diagnosis of Autistic Spectrum Disorders
Filipek, P. A., Accardo, P., Baranek, G. T., Cook, E. H., Dawson, G., Gordon, B., Gravel, J. S., Johnson, C. P., Kallen, R. J., Levy, S. E., et al. (1999) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1021943802493 · Cited by 996 · see citing works
Self-citationZwaigenbaum, L., Bauman, M. L., Choueiri, R., Kasari, C., Carter, A., Granpeesheh, D., Mailloux, Z., Smith Roley, S., Wagner, S., Fein, D., et al. (2015) · Pediatrics · doi:10.1542/peds.2014-3667e · Cited by 856 · see citing works
Tuchman, R. F., & Rapin, I. (2002) · The Lancet Neurology · doi:10.1016/s1474-4422(02)00160-6 · Cited by 713 · see citing works
Self-citationAmiet, C., Gourfinkel-An, I., Bouzamondo, A., Tordjman, S., Baulac, M., Lechat, P., Mottron, L., & Cohen, D. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.04.030 · Cited by 499 · see citing works
Tuchman, R. F., & Rapin, I. (1997) · PEDIATRICS · doi:10.1542/peds.99.4.560 · Cited by 470 · see citing works
Self-citationThe role of epilepsy and epileptiform EEGs in autism spectrum disorders
Spence, S. J., & Schneider, M. T. (2009) · Pediatric Research · doi:10.1203/pdr.0b013e31819e7168 · Cited by 418 · see citing works
Medical Comorbidities in Autism: Challenges to Diagnosis and Treatment
Bauman, M. L. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.06.001 · Cited by 372 · see citing works
Epilepsy in autism spectrum disorders
Canitano, R. (2006) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-006-0563-2 · Cited by 308 · see citing works
Danielsson, S., Gillberg, I. C., Billstedt, E., Gillberg, C., & Olssøn, I. (2005) · Epilepsia · doi:10.1111/j.1528-1167.2005.57504.x · Cited by 296 · see citing works
Autism and Known Medical Conditions: Myth and Substance
Rutter, M. L., Bailey, A. J., Bolton, P., & Couteur, A. S. L. (1994) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1994.tb01164.x · Cited by 287 · see citing works
Chez, M. G., Chang, M., Krasne, V., Coughlan, C. A., Kominsky, M., & Schwartz, A. (2006) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2005.11.001 · Cited by 275 · see citing works
Comorbidity in autism spectrum disorder: a literature review
Mannion, A., & Leader, G. (2013) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2013.09.006 · Cited by 271 · see citing works
Autism spectrum disorders: Concurrent clinical disorders
Ming, X., Brimacombe, M., Chaaban, J., Zimmerman-Bier, B., & Wagner, G. C. (2008) · Journal of Child Neurology · doi:10.1177/0883073807307102 · Cited by 266 · see citing works
Lewine, J. D., Andrews, R., Chez, M., Patil, A.-A., Devinsky, O., Smith, M., Kanner, A., Davis, J. T., Funke, M., Jones, G., et al. (1999) · PEDIATRICS · doi:10.1542/peds.104.3.405 · Cited by 258 · see citing works
Update on the Epidemiology and Prognosis of Pediatric Epilepsy
Shinnar, S., & Pellock, J. M. (2002) · Journal of Child Neurology · doi:10.1177/08830738020170010201 · Cited by 257 · see citing works
Self-citationAutism and epilepsy: A retrospective follow-up study
Hara, H. (2007) · Brain and Development · doi:10.1016/j.braindev.2006.12.012 · Cited by 242 · see citing works
Psychiatric problems in individuals with autism, their parents and siblings
Lainhart, J. E. (1999) · International Review of Psychiatry · doi:10.1080/09540269974177 · Cited by 242 · see citing works
Cognitive and neurodevelopmental comorbidities in paediatric epilepsy
Nickels, K. C., Zaccariello, M. J., Hamiwka, L. D., & Wirrell, E. C. (2016) · Nature Reviews Neurology · doi:10.1038/nrneurol.2016.98 · Cited by 238 · see citing works
Clinical characteristics of children with autism spectrum disorder and co-occurring epilepsy.
Viscidi, E. W., Triche, E. W., Pescosolido, M. F., McLean, R. L., Joseph, R. M., Spence, S. J., & Morrow, E. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067797 · Cited by 235 · see citing works
Chez, M. G., Buchanan, C. P., Aimonovitch, M. C., Becker, M., Schaefer, K., Black, C., & Komen, J. (2002) · Journal of Child Neurology · doi:10.1177/08830738020170111501 · Cited by 221 · see citing works
Ballaban‐Gil, K. R., Rapin, I., Tuchman, R. F., & Shinnar, S. (1996) · Pediatric Neurology · doi:10.1016/s0887-8994(96)00219-6 · Cited by 217 · see citing works
Self-citationEpidemiological Studies of Pervasive Developmental Disorders
Fombonne, E. J. (2005) · Wiley eBooks · doi:10.1002/9780470939345.ch2 · Cited by 204 · see citing works
Associated Medical Disorders and Disabilities in Children with Autistic Disorder
Kielinen, M., Rantala, H., Timonen, E., Linna, S., & Moilanen, I. K. (2004) · Autism · doi:10.1177/1362361304040638 · Cited by 198 · see citing works
EEG features and epilepsy in patients with autism
Rossi, P. G., Parmeggiani, A., Bach, V., Santucci, M., & Visconti, P. (1995) · Brain and Development · doi:10.1016/0387-7604(95)00019-8 · Cited by 197 · see citing works
Mannion, A., Leader, G., & Healy, O. (2013) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2012.05.002 · Cited by 195 · see citing works
Electrical Status Epilepticus in Sleep
Nickels, K. C., & Wirrell, E. C. (2008) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2008.03.002 · Cited by 180 · see citing works
Epilepsy, cognition, and behavior: The clinical picture
Berg, A. T. (2011) · Epilepsia · doi:10.1111/j.1528-1167.2010.02905.x · Cited by 178 · see citing works
Tye, C., Runicles, A. K., Whitehouse, A. J. O., & Alvares, G. A. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00751 · Cited by 177 · see citing works
Giannotti, F., Cortesi, F., Cerquiglini, A., Miraglia, D., Vagnoni, C., Sebastiani, T., & Bernabei, P. (2008) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-008-0584-4 · Cited by 176 · see citing works
Autism and epilepsy: Historical perspective
Tuchman, R., Cuccaro, M., & Alessandri, M. (2010) · Brain and Development · doi:10.1016/j.braindev.2010.04.008 · Cited by 172 · see citing works
Self-citationEpilepsy genes: The link between molecular dysfunction and pathophysiology
Stafstrom, C. E., & Tempel, B. L. (2000) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/1098-2779(2000)6:4 · Cited by 15 · see citing works
Self-citationLanguage regression in childhood
Shinnar, S., Rapin, I., Arnold, S., Tuchman, R. F., Shulman, L., Ballaban‐Gil, K. R., Maw, M., Deuel, R. K., & Volkmar, F. R. (2001) · Pediatric Neurology · doi:10.1016/s0887-8994(00)00266-6 · Cited by 160 · see citing works
Self-citationChugani, H. T., da Silva, E. D., & Chugani, D. (1996) · Annals of Neurology · doi:10.1002/ana.410390514 · Cited by 147 · see citing works
Achkar, C. M. E., & Spence, S. J. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.12.022 · Cited by 159 · see citing works
Gabriels, R. L., Agnew, J., Miller, L. J., Gralla, J., Pan, Z., Goldson, E., Ledbetter, J. C., Dinkins, J. P., & Hooks, E. N. (2008) · Research in Autism · doi:10.1016/j.rasd.2008.02.002 · Cited by 156 · see citing works
Epilepsy, Electroencephalographic Abnormalities, and Regression in Children With Autism
Canitano, R., Luchetti, A., & Zappella, M. (2005) · Journal of Child Neurology · doi:10.1177/08830738050200010401 · Cited by 149 · see citing works
Autism Spectrum Disorder and Epilepsy
Jeste, S., & Tuchman, R. F. (2015) · Journal of Child Neurology · doi:10.1177/0883073815601501 · Cited by 147 · see citing works
Self-citationEpilepsy and autism: Is there a special relationship?
Berg, A. T., & Plioplys, S. (2012) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2012.01.015 · Cited by 144 · see citing works
Epilepsy in adolescents and young adults with autistic disorder
Rossi, P. G., Posar, A., & Parmeggiani, A. (2000) · Brain and Development · doi:10.1016/s0387-7604(99)00124-2 · Cited by 144 · see citing works
Convulsing toward the pathophysiology of autism
Tuchman, R., Moshé, S. L., & Rapin, I. (2009) · Brain and Development · doi:10.1016/j.braindev.2008.09.009 · Cited by 142 · see citing works
Self-citationAutism and epilepsy: Cause, consequence, comorbidity, or coincidence?
Gabis, L. V., Pomeroy, J. C., & Andriola, M. R. (2005) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2005.08.008 · Cited by 142 · see citing works
Caring for the Child With an Autism Spectrum Disorder in the Acute Care Setting
Scarpinato, N., Bradley, J., Kurbjun, K., Bateman, X., Holtzer, B. M., & Ely, B. (2010) · Journal for Specialists in Pediatric Nursing · doi:10.1111/j.1744-6155.2010.00244.x · Cited by 138 · see citing works
Kim, H. L., Donnelly, J. H., Tournay, A. E., Book, T. M., & Filipek, P. A. (2006) · Epilepsia · doi:10.1111/j.1528-1167.2006.00434.x · Cited by 129 · see citing works
Epilepsy and EEG paroxysmal abnormalities in autism spectrum disorders
Parmeggiani, A., Barcia, G., Posar, A., Raimondi, E., Santucci, M., & Scaduto, M. C. (2010) · Brain and Development · doi:10.1016/j.braindev.2010.07.003 · Cited by 128 · see citing works
Hrdlička, M., Komárek, V., Propper, L., Kulísek, R., Zumrová, A., Faladová, L., Havlovičová, M., Sedláček, Z., Blatný, M., & Urbánek, T. (2004) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-004-0353-7 · Cited by 122 · see citing works
In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders
Pantazopoulos, H., & Berretta, S. (2015) · Neural Plasticity · doi:10.1155/2016/9847696 · Cited by 118 · see citing works
Li, B.-M., Liu, X., Yi, Y., Deng, Y., Su, T., Zou, X., & Liao, W. (2011) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2011.04.060 · Cited by 116 · see citing works
Autistic Spectrum Disorder: Evaluating a Possible Contributing or Causal Role of Epilepsy
Deonna, T. W., & Roulet, E. (2006) · Epilepsia · doi:10.1111/j.1528-1167.2006.00697.x · Cited by 111 · see citing works
Autismo e doenças invasivas de desenvolvimento
Gadia, C. A., Tuchman, R. F., & Rotta, N. T. (2004) · Jornal de Pediatria · doi:10.1590/s0021-75572004000300011 · Cited by 108 · see citing works
Self-citationEpilepsy Among Children and Adolescents with Autism Spectrum Disorders: A Population-Based Study
Jokiranta‐Olkoniemi, E., Sourander, A., Suominen, A., Timonen‐Soivio, L., Brown, A. S., & Sillanpää, M. L. (2014) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-014-2126-6 · Cited by 103 · see citing works
Differences in the clinical presentation of Trisomy 21 with and without autism
Molloy, C. A., Murray, D. S., Kinsman, A. M., Castillo, H. A., Mitchell, T., Hickey, F. J., & Patterson, B. (2008) · Journal of Intellectual Disability Research · doi:10.1111/j.1365-2788.2008.01138.x · Cited by 106 · see citing works
Autistic regression and disintegrative disorder: How important the role of epilepsy?
Rapin, I. (1995) · Seminars in Pediatric Neurology · doi:10.1016/s1071-9091(95)80007-7 · Cited by 104 · see citing works
Self-citationScreening Electroencephalograms in Autism Spectrum Disorders: Evidence-Based Guideline
Kagan-Kushnir, T., Roberts, S. W., & Snead, O. C. (2005) · Journal of Child Neurology · doi:10.1177/08830738050200030601 · Cited by 103 · see citing works
Language disorders in children with autism
Rapin, I., & Dunn, M. A. (1997) · Seminars in Pediatric Neurology · doi:10.1016/s1071-9091(97)80024-1 · Cited by 100 · see citing works
Self-citationRisk and Correlates of Autism Spectrum Disorder in Children With Epilepsy: A Community-Based Study
Berg, A. T., Plioplys, S., & Tuchman, R. F. (2011) · Journal of Child Neurology · doi:10.1177/0883073810384869 · Cited by 100 · see citing works
Self-citationSæmundsen, E., Lúðvígsson, P., Hilmarsdottir, I., & Rafnsson, V. (2007) · Epilepsia · doi:10.1111/j.1528-1167.2007.01150.x · Cited by 97 · see citing works
Autism: Electroencephalogram Abnormalities and Clinical Improvement With Valproic Acid
Plioplys, A. V. (1994) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1994.02170020106021 · Cited by 96 · see citing works
Childhood epilepsy in relation to mental handicap and behavioural disorders
Besag, F. (2002) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00006 · Cited by 95 · see citing works
Shelley, B. P., Trimble, M., & Boutros, N. N. (2008) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.20.1.7 · Cited by 93 · see citing works
Epileptic electroencephalographic abnormalities and developmental dysphasias: A study of 32 patients
Échenne, B., Cheminai, R., Rivier, F., Nègre, C., Touchon, J., & Billiard, M. M. (1992) · Brain and Development · doi:10.1016/s0387-7604(12)80233-6 · Cited by 93 · see citing works
Epilepsy in disintegrative psychosis and infantile autism: a long-term validation study
Mouridsen, S. E., Rich, B., & Isager, T. (1999) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162299000213 · Cited by 93 · see citing works
Neumeyer, A. M., Anixt, J. S., Chan, J. G. M., Perrin, J. M., Murray, D. S., Coury, D. L., Bennett, A. E., Farmer, J. G., & Parker, R. A. (2018) · Academic Pediatrics · doi:10.1016/j.acap.2018.06.014 · Cited by 90 · see citing works
Braida, D., Guerini, F., Ponzoni, L., Corradini, I., Astis, S. D., Pattini, L., Bolognesi, E., Benfante, R., Fornasari, D., Chiappedi, M., et al. (2015) · Translational Psychiatry · doi:10.1038/tp.2014.136 · Cited by 88 · see citing works
EpilepsyGene: a genetic resource for genes and mutations related to epilepsy
Xia, R., Li, J., Shao, Q., Chen, H., Lin, Z., Sun, Z. S., & Wu, J. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku943 · Cited by 86 · see citing works
Antiepileptic drugs: affective use in autism spectrum disorders
Martino, A. D., & Tuchman, R. F. (2001) · Pediatric Neurology · doi:10.1016/s0887-8994(01)00276-4 · Cited by 85 · see citing works
Self-citationKawasaki, Y., Yokota, K., Shinomiya, M., Shimizu, Y., & Niwa, S. (1997) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1025886228387 · Cited by 85 · see citing works
Viscidi, E. W., Johnson, A. L., Spence, S. J., Buka, S. L., Morrow, E. M., & Triche, E. W. (2014) · Autism · doi:10.1177/1362361313508027 · Cited by 82 · see citing works
Treatment of Seizure Disorders and EEG Abnormalities in Children with Autism Spectrum Disorders
Tuchman, R. F. (2000) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1005572128200 · Cited by 82 · see citing works
Self-citationMinshew, N. J., Sweeney, J. A., Bauman, M. L., & Webb, S. J. (2005) · doi:10.1002/9780470939345.ch18 · Cited by 78 · see citing works
Overvliet, G. M., Besseling, R. M. H., Vles, J. S. H., Hofman, P. A. M., Backes, W. H., van Hall, M. H. J. A., Klinkenberg, S., Hendriksen, J. G. M., & Aldenkamp, A. P. (2010) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2010.09.015 · Cited by 76 · see citing works
Clinical characteristics of language regression in children
Sy, W., Djukic, A., Shinnar, S., Dharmani, C., Rapin, I., & Korey, S. R. (2003) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.2003.tb00950.x · Cited by 74 · see citing works
Self-citationMedically refractory epilepsy in autism
Sansa, G., Carlson, C., Doyle, W., Weiner, H. L., Bluvstein, J., Barr, W., & Devinsky, O. (2011) · Epilepsia · doi:10.1111/j.1528-1167.2011.03069.x · Cited by 71 · see citing works
McVicar, K. A., & Shinnar, S. (2004) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20028 · Cited by 68 · see citing works
Self-citationAutism spectrum disorder: Screening, diagnosis, and medical evaluation
Spence, S. J., Sharifi‐Hannauer, P., & Wiznitzer, M. (2004) · Seminars in Pediatric Neurology · doi:10.1016/j.spen.2004.07.002 · Cited by 63 · see citing works
Epilepsy and autism severity: a study of 6,975 children
Ewen, J. B., Marvin, A. R., Law, K., & Lipkin, P. H. (2019) · Autism Research · doi:10.1002/aur.2132 · Cited by 56 · see citing works
Connolly, J. J., Glessner, J., & Hakonarson, H. H. (2012) · Child Development · doi:10.1111/j.1467-8624.2012.01838.x · Cited by 62 · see citing works
Seizures and Epilepsy Among Children With Language Regression and Autistic Spectrum Disorders
Trevathan, E. (2004) · Journal of Child Neurology · doi:10.1177/088307380401900106 · Cited by 60 · see citing works
EEG abnormalities and epilepsy in autistic spectrum disorders: Clinical and familial correlates
Ekıncı, O., Arman, A. R., Işık, U., Bez, Y., & Berkem, M. (2009) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2009.11.014 · Cited by 61 · see citing works
CSWS‐related autistic regression versus autistic regression without CSWS
Tuchman, R. F. (2009) · Epilepsia · doi:10.1111/j.1528-1167.2009.02212.x · Cited by 59 · see citing works
Self-citationAutism and pervasive developmental disorders
Gadia, C. A., Tuchman, R. F., & Rotta, N. T. (2004) · Jornal de Pediatria · doi:10.2223/1172 · Cited by 58 · see citing works
Self-citationEpilepsy surgery in children with pervasive developmental disorder
Szabó, C. Á., Wyllie, E., Dolske, M. C., Stanford, L. D., Kotagal, P., & Comair, Y. G. (1999) · Pediatric Neurology · doi:10.1016/s0887-8994(99)00003-x · Cited by 59 · see citing works
EEG Sedation for Children with Autism
Mehta, U., PATEL, I., & Castello, F. V. (2004) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200404000-00005 · Cited by 58 · see citing works
El-Ansary, A. K., Al-Daihan, S., Al-Dbass, A. M., & AL-Ayadhi, L. Y. (2009) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2009.09.008 · Cited by 58 · see citing works
Paroxysmal discharges on EEG in young autistic patients are frequent in frontal regions.
Hashimoto, T., Sasaki, M., Sugai, K., Hanaoka, S., Fukumizu, M., & Kato, T. (2001) · PubMed · Cited by 56 · see citing works
Autistic regression and Landau‐Kleffner syndrome: progress or confusion?
Mantovani, J. F. (2000) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162200210621 · Cited by 56 · see citing works
Prévost, P., Tuller, L., Barthez, M. A., Malvy, J., & Bonnet‐Brilhault, F. (2017) · Applied Psycholinguistics · doi:10.1017/s0142716417000078 · Cited by 55 · see citing works
Noh, H. J., Ponting, C. P., Boulding, H. C., Meader, S., Betancur, C., Buxbaum, J. D., Pinto, D., Marshall, C. R., Lionel, A. C., Scherer, S. W., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003523 · Cited by 54 · see citing works
Pediatric indications for deep brain stimulation
DiFrancesco, M. F., Halpern, C. H., Hurtig, H. H., Baltuch, G. H., & Heuer, G. G. (2012) · Child s Nervous System · doi:10.1007/s00381-012-1861-2 · Cited by 53 · see citing works
Neuropsychiatric Aspects of Epilepsy
Tolchin, B. D., Hirsch, L. J., & LaFrance, W. C., Jr. (2020) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2020.02.002 · Cited by 53 · see citing works
Autism: A review of biological bases, assessment, and intervention.
Volker, M. A., & Lopata, C. J. (2008) · School Psychology Quarterly · doi:10.1037/1045-3830.23.2.258 · Cited by 51 · see citing works
Autism and Epilepsy: What Has Regression Got to Do with It?
Tuchman, R. F. (2006) · Epiliepsy currents/Epilepsy currents · doi:10.1111/j.1535-7511.2006.00113.x · Cited by 52 · see citing works
Self-citationTharp, B. R. (2004) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20025 · Cited by 50 · see citing works
Prévost, P., Tuller, L., Zebib, R., Barthez, M. A., Malvy, J., & Bonnet‐Brilhault, F. (2018) · Autism & Developmental Language Impairments · doi:10.1177/2396941518799643 · Cited by 48 · see citing works
Specific Neurological Phenotypes in Autism Spectrum Disorders Are Associated with Sex Representation
Ben‐Itzchak, E., Ben‐Shachar, S., & Zachor, D. A. (2013) · Autism Research · doi:10.1002/aur.1319 · Cited by 48 · see citing works
Seizures and epilepsy and their relationship to autism spectrum disorders
Matson, J. L., & Neal, D. (2009) · Research in Autism · doi:10.1016/j.rasd.2009.06.003 · Cited by 44 · see citing works
Medical Conditions in the First Years of Life Associated with Future Diagnosis of ASD in Children
Alexeeff, S., Yau, V. M., Qian, Y., Davignon, M. N., Lynch, F. L., Crawford, P. M., Davis, R. E., & Croen, L. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3130-4 · Cited by 43 · see citing works
Filipek, P. A. (2005) · Wiley eBooks · doi:10.1002/9780470939345.ch20 · Cited by 43 · see citing works
- Authors
- Tuchman, R. F., Rapin, I., & Shinnar, S.
- Affiliations
- Albert Einstein College of Medicine (US)
- ORCID
- Shinnar, Shlomo
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 1991-12-01
- Volume
- 88
- Issue
- 6
- Pages
- 1219-1225
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W1888407996
- Cited by
- 251
- References
- 4
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 6 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 8 · 2016: 13 · 2015: 14 · 2014: 5 · 2013: 8 · 2012: 11
- FWCI
- 1.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- PEDIATRICS (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5k07ns000930-05)
- U.S. Public Health Service (20489)
- National Institute of Neurological Disorders and Stroke (1 RO1 NS26151, R01NS026151, 1K07 NS00930)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Epilepsy research and treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- autism spectrum disorder, dysphasia, epilepsy, risk factors, intellectual disability, motor impairment, language disorders, sex differences, family history of epilepsy, perinatal disorders, children
- MeSH terms
- Aphasia, Autistic Disorder, Child, Preschool, Epilepsy, Female, Humans, Intelligence, Male, Intellectual Disability, Psychomotor Disorders, Risk Factors, Seizures, Sex Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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