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Cited by 265

The DOI matches its Crossref record; 171 of the 171 references it cites were found in a registry or an index.

Prevention and treatment of Staphylococcus aureus biofilms

Open access
Bhattacharya, Mohini, Wozniak, Daniel J, Stoodley, Paul, Hall-Stoodley, Luanne·2015·Expert Review of Anti-infective Therapy

Abstract

S. aureus colonizes both artificial and tissue surfaces in humans causing chronic persistent infections that are difficult to cure. It is a notorious pathogen due to its antibiotic recalcitrance and phenotypic adaptability, both of which are facilitated by its ability to develop biofilms. S. aureus biofilms challenge conventional anti-infective approaches, most notably antibiotic therapy. Therefore there is an unmet need to develop and include parallel approaches that target S. aureus biofilm infections. This review discusses two broad anti-infective strategies: (1) preventative approaches (anti-biofilm surface coatings, the inclusion of biofilm-specific vaccine antigens); and (2) approaches aimed at eradicating established S. aureus biofilms, particularly those associated with implant infections. Advances in understanding the distinct nature of S. aureus biofilm development and pathogenesis have led to growing optimism in S. aureus biofilm targeted anti-infective strategies. Further research is needed however, to see the successful administration and validation of these approaches to the diverse types of infections caused by S. aureus biofilms from multiple clinical strains.

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Crossref · 10.1586/14787210.2015.1100533

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Metadata

Authors
Bhattacharya, M., Wozniak, D. J., Stoodley, P., & Hall-Stoodley, L.
Venue
Expert Review of Anti-infective Therapy
Published
2015-11-13
Volume
13
Issue
12
Pages
1499-1516
ISSN
  • 1478-7210 (ISSN-L)
  • 1744-8336
OpenAlex
W2175125938
Cited by
265
References
171
FWCI
4.50
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Prevention and treatment of Staphylococcus aureus biofilms. https://app.cochat.ai/papers/10.1586/14787210.2015.1100533
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Bhattacharya, M., Wozniak, D. J., Stoodley, P., & Hall-Stoodley, L. (2015). Prevention and treatment of Staphylococcus aureus biofilms. Expert Review of Anti-infective Therapy. https://doi.org/10.1586/14787210.2015.1100533

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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