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Cited by 68Phytochemicals and Antioxidant ActivitiesPhytochemistry and Biological ActivitiesMedicinal Plant Research

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

Quantification of chlorogenic acid, rosmarinic acid, and caffeic acid contents in selected Thai medicinal plants using RP-HPLC-DAD

Open access
Chaowuttikul, Chayanon, Palanuvej, Chanida, Ruangrungsi, Nijsiri·2020·Brazilian Journal of Pharmaceutical Sciences
DOI 10.1590/s2175-97902019000317547
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Abstract

The chlorogenic acid, rosmarinic acid, and caffeic acid contents in 100 selected plants were determined using reversed phase high performance liquid chromatography equipped with diode array detector. The optimum condition was 0.2% phosphoric acid in water (solvent A) and methanol (solvent B) as the mobile phase, which was set at 45% B for 20 minutes at a flow rate of 1.2 mL/min. The column temperature was maintained at 30 ºC and the detection wavelength was 325 nm. Among 100 selected plants, 39.64% contained all 3 compounds, 40.54% contained 2 compounds, 14.41% contained only 1 compound, and 5.41% could not detect any of the 3 compounds. The highest contents of chlorogenic acid, rosmarinic acid, and caffeic acid were found in Lonicera japonica flowering buds, Melissa officinalis leaves, and Coffea canephora seeds at the concentration of 9.900 ± 0.004, 19.908 ± 0.171, and 1.233 ± 0.003 g/100 g of dried plant, respectively.

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Registry

Crossref · 10.1590/s2175-97902019000317547

Cites

15 of 15 references verified0 citation errors · 0 not checkable

Statistics

Figures

FIGURE 1 Structures of caffeic acid (A), chlorogenic acid (B) and rosmarinic acid (C).
FIGURE 1 Structures of caffeic acid (A), chlorogenic acid (B) and rosmarinic acid (C).CC-BY · From the PDF
Image 2
CC-BY · From the PDF
Image 3
CC-BY · From the PDF
FIGURE 2 HPLC chromatogram of standard chlorogenic acid, rosmarinic acid and caffeic acid at 325 nm by RP-HPLC-DAD.
FIGURE 2 HPLC chromatogram of standard chlorogenic acid, rosmarinic acid and caffeic acid at 325 nm by RP-HPLC-DAD.CC-BY · From the PDF
FIGURE 3 The calibration curve of chlorogenic acid.
FIGURE 3 The calibration curve of chlorogenic acid.CC-BY · From the PDF
Image 6
CC-BY · From the PDF
FIGURE 5 The calibration curve of caffeic acid.
FIGURE 5 The calibration curve of caffeic acid.CC-BY · From the PDF
FIGURE 6 The peak purity of chlorogenic acid in L. japonica flowering bud ethanolic extract (Peak purity index: 1.000000).
FIGURE 6 The peak purity of chlorogenic acid in L. japonica flowering bud ethanolic extract (Peak purity index: 1.000000).CC-BY · From the PDF
FIGURE 7 The peak purity of rosmarinic acid in L. japonica flowering bud ethanolic extract (Peak purity index: 0.999952).
FIGURE 7 The peak purity of rosmarinic acid in L. japonica flowering bud ethanolic extract (Peak purity index: 0.999952).CC-BY · From the PDF
FIGURE 8 The peak purity of caffeic acid in L. japonica flowering bud ethanolic extract (Peak purity index: 0.999999).
FIGURE 8 The peak purity of caffeic acid in L. japonica flowering bud ethanolic extract (Peak purity index: 0.999999).CC-BY · From the PDF

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Citations

Cites

Show all 15 references

Research works printed but not linked: 1

  1. Zeng JG, 2011, Standardization and quality control of herbal extracts and products, 377

Cited by

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Metadata

Authors
Chaowuttikul, C., Palanuvej, C., & Ruangrungsi, N.
Affiliations
Chulalongkorn University (TH)
ORCID
Palanuvej, Chanida
Venue
Brazilian Journal of Pharmaceutical Sciences
Publisher
FapUNIFESP (SciELO)
Published
2020
Volume
56
ISSN
  • 1984-8250 (ISSN-L)
  • 2175-9790
DOI
10.1590/s2175-97902019000317547
OpenAlex
W3011533417
Cited by
68
References
15
Citations by year
2026: 11 · 2025: 15 · 2024: 14 · 2023: 5 · 2022: 8 · 2021: 11 · 2020: 4
FWCI
3.79
Type
journal article
Language
en
Open access
Licence
Locations
  • Brazilian Journal of Pharmaceutical Sciences (publishedVersion, cc-by)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
  • Americanae (AECID Library) (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, cc-by)
Funders
Chulalongkorn University
Topics
  • Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
Keywords
chlorogenic acid, rosmarinic acid, caffeic acid, Thai medicinal plants, phytochemical quantification, Lonicera japonica, lemon balm, Coffea canephora, flavonoids

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CoChat. (2026). Citation check: Quantification of chlorogenic acid, rosmarinic acid, and caffeic acid contents in selected Thai medicinal plants using RP-HPLC-DAD. https://app.cochat.ai/papers/10.1590/s2175-97902019000317547
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Chaowuttikul, C., Palanuvej, C., & Ruangrungsi, N. (2020). Quantification of chlorogenic acid, rosmarinic acid, and caffeic acid contents in selected Thai medicinal plants using RP-HPLC-DAD. Brazilian Journal of Pharmaceutical Sciences. https://doi.org/10.1590/s2175-97902019000317547

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