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Embryonic anti-aging niche.
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Mouse primary myoblasts can be used for determining the effects of proteins secreted by human cells on myogenic cell proliferation and differentiation.
“We previously established that mouse primary myoblasts can be used for determining the effects of the proteins that are secreted by human cells on myogenic cell proliferation and differentiation [15, 19, 20].”
From Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin (2020) · cites this paper as [19]
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Cites
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“While the senescent niche can signal its own clearance via the immune system, some senescent cells persist and produce cytokines, causing chronic inflammation and tissue aging [27-29].”
BackgroundIncreased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
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Self-citationNotch-Mediated Restoration of Regenerative Potential to Aged Muscle
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Self-citationRibosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span
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“Likewise, genetic inactivation of the cyclindependent kinase (CDK) inhibitor, p16 was shown to rejuvenate responses of tissue dedicated stem cells in blood, brain and pancreas, while the over-expression of p16 caused premature aging of lymphocytes [22-26].”
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“Likewise, genetic inactivation of the cyclindependent kinase (CDK) inhibitor, p16 was shown to rejuvenate responses of tissue dedicated stem cells in blood, brain and pancreas, while the over-expression of p16 caused premature aging of lymphocytes [22-26].”
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Self-citationTelomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
Tomás-Loba, A., Flores, I., Fernández-Marcos, P. J., Cayuela, M. L., Maraver, A., Tejera, A., Borrás, C., Matheu, A., Klatt, P., Flores, J. M., et al. (2008) · Cell · doi:10.1016/j.cell.2008.09.034 · Cited by 484 · cited 1×
“Interestingly, the expression of moderately increased levels of p19ARF/p53 cell-cycle inhibitors in transgenic mice that also over-express telomerase promoted the longevity and decreased the biomarkers of aging [30].”
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Flagged first, then by citations
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Cited by
Sorted by citations
Elabd, C., Cousin, W., Upadhyayula, P., Chen, R. Y., Chooljian, M. S., Li, J., Kung, S., Jiang, K. P., & Conboy, I. M. (2014) · Nature Communications · doi:10.1038/ncomms5082 · Cited by 411
Self-citationHeterochronic parabiosis for the study of the effects of aging on stem cells and their niches
Conboy, I. M., & Rando, T. A. (2012) · Cell Cycle · doi:10.4161/cc.20437 · Cited by 239
Self-citationRejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin
Mehdipour, M., Skinner, C., Wong, N., Lieb, M., Liu, C., Etienne, J., Kato, C., Kiprov, D., Conboy, M. J., & Conboy, I. M. (2020) · Aging · doi:10.18632/aging.103418 · Cited by 115
Self-citation
Metadata
- Authors
- Conboy, I. M., Yousef, H., & Conboy, M. J.
- Affiliations
- Department of Bioengineering and QB3 Institute, UC Berkeley, Berkeley, CA 94720-3220, USA
- Department of Molecular and Cellular Biology, UC Berkeley, Berkeley, CA 94720-3200, USA
- Venue
- Aging
- Publisher
- Impact Journals, LLC
- Published
- 2011-05-31
- Volume
- 3
- Issue
- 5
- Pages
- 555-563
- ISSN
- 1945-4589
- PMC
- PMC3156606
- Cited by
- 33
- References
- 19
- Language
- en
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