The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents
Open accessAbstract
The effectiveness of anticancer agents may be hindered by low solubility in water, poor permeability, and high efflux from cells. Nanomaterials have been used to enable drug delivery with lower toxicity to healthy cells and enhanced drug delivery to tumor cells. Different nanoparticles have been developed using different polymers with or without surface modification to target tumor cells both passively and/or actively. Polylactide-co-glycolide (PLGA), a biodegradable polyester approved for human use, has been used extensively. Here we report on recent developments concerning PLGA nanoparticles prepared for cancer treatment. We review the methods used for the preparation and characterization of PLGA nanoparticles and their applications in the delivery of a number of active agents. Increasing experience in the field of preparation, characterization, and in vivo application of PLGA nanoparticles has provided the necessary momentum for promising future use of these agents in cancer treatment, with higher efficacy and fewer side effects.
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Cites
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Vitamin E TPGS as a molecular biomaterial for drug delivery
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Customizing poly(lactic-co-glycolic acid) particles for biomedical applications
Swider, E., Koshkina, O., Tel, J., Cruz, L. J., de Vries, I. J. M., & Srinivas, M. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.04.006 · Cited by 328
PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up
Operti, M. C., Bernhardt, A., Grimm, S., Engel, A., Figdor, C. G., & Tagit, O. (2021) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2021.120807 · Cited by 302
Recent developments in the use of nanoparticles for treatment of biofilms
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Metadata
- Authors
- Dinarvand, R., Sepehri, N., Manouchehri, Rouhani, & Atyabi, F.
- Venue
- International Journal of Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2011-04
- Volume
- 6
- Pages
- 877
- ISSN
- 1176-9114 (ISSN-L)
- 1178-2013
- OpenAlex
- W1977718036
- Cited by
- 453
- References
- 19
- FWCI
- 11.36
- Type
- journal article
- Language
- en
- Open access
- gold
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- Dinarvand, R., Sepehri, N., Manouchehri, Rouhani, & Atyabi, F. (2011). Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents. International Journal of Nanomedicine. https://doi.org/10.2147/ijn.s18905
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
