The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Clinical development of liposome based drugs: formulation, characterization, and therapeutic efficacy
Open accessAbstract
Research on liposome formulations has progressed from that on conventional vesicles to new generation liposomes, such as cationic liposomes, temperature sensitive liposomes, and virosomes, by modulating the formulation techniques and lipid composition. Many research papers focus on the correlation of blood circulation time and drug accumulation in target tissues with physicochemical properties of liposomal formulations, including particle size, membrane lamellarity, surface charge, permeability, encapsulation volume, shelf time, and release rate. This review is mainly to compare the therapeutic effect of current clinically approved liposome-based drugs with free drugs, and to also determine the clinical effect via liposomal variations in lipid composition. Furthermore, the major preclinical and clinical data related to the principal liposomal formulations are also summarized.
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Cites
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Cited by
Advances and Challenges of Liposome Assisted Drug Delivery
Sercombe, L., Veerati, T., Moheimani, F., Wu, S. Y., Sood, A. K., & Hua, S. (2015) · Frontiers in Pharmacology · doi:10.3389/fphar.2015.00286 · Cited by 2,632
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Liposomes: Structure, composition, types, and clinical applications
Nsairat, H., Khater, D., Sayed, U., Odeh, F., Al Bawab, A., & Alshaer, W. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e09394 · Cited by 1,561
The Smart Drug Delivery System and Its Clinical Potential
Liu, D., Yang, F., Xiong, F., & Gu, N. (2016) · Theranostics · doi:10.7150/thno.14858 · Cited by 1,066
Lombardo, D., Kiselev, M. A., & Caccamo, M. T. (2019) · Journal of Nanomaterials · doi:10.1155/2019/3702518 · Cited by 864
Metadata
- Authors
- Yeh, M.-K., Chang, H.-I., & Cheng, M.-Y.
- Venue
- International Journal of Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2011-12
- Volume
- 7
- Pages
- 49
- ISSN
- 1176-9114 (ISSN-L)
- 1178-2013
- OpenAlex
- W2108471741
- Cited by
- 801
- References
- 73
- FWCI
- 15.31
- Type
- journal article
- Language
- en
- Open access
- gold
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- Yeh, M.-K., Chang, H.-I., & Cheng, M.-Y. (2011). Clinical development of liposome based drugs: formulation, characterization, and therapeutic efficacy. International Journal of Nanomedicine. https://doi.org/10.2147/ijn.s26766
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.