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Cited by 801

The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.

Clinical development of liposome based drugs: formulation, characterization, and therapeutic efficacy

Open access
Yeh, Ming-Kung, Hsin-I Chang, Ming-Yen Cheng·2011·International Journal of Nanomedicine

Abstract

Research on liposome formulations has progressed from that on conventional vesicles to new generation liposomes, such as cationic liposomes, temperature sensitive liposomes, and virosomes, by modulating the formulation techniques and lipid composition. Many research papers focus on the correlation of blood circulation time and drug accumulation in target tissues with physicochemical properties of liposomal formulations, including particle size, membrane lamellarity, surface charge, permeability, encapsulation volume, shelf time, and release rate. This review is mainly to compare the therapeutic effect of current clinically approved liposome-based drugs with free drugs, and to also determine the clinical effect via liposomal variations in lipid composition. Furthermore, the major preclinical and clinical data related to the principal liposomal formulations are also summarized.

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Crossref · 10.2147/ijn.s26766

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Metadata

Authors
Yeh, M.-K., Chang, H.-I., & Cheng, M.-Y.
Venue
International Journal of Nanomedicine
Published
2011-12
Volume
7
Pages
49
ISSN
  • 1176-9114 (ISSN-L)
  • 1178-2013
OpenAlex
W2108471741
Cited by
801
References
73
FWCI
15.31
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Clinical development of liposome based drugs: formulation, characterization, and therapeutic efficacy. https://app.cochat.ai/papers/10.2147/ijn.s26766
The paper
Yeh, M.-K., Chang, H.-I., & Cheng, M.-Y. (2011). Clinical development of liposome based drugs: formulation, characterization, and therapeutic efficacy. International Journal of Nanomedicine. https://doi.org/10.2147/ijn.s26766

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.