Sleep, Sex Steroid Hormones, Sexual Activities, and Aging in Asian Men
Open accessAbstract
ABSTRACT: This was a cross‐sectional study to examine the different associations of age and sleep duration with sex steroid hormones and sexual activities in 531 Asian Chinese men aged between 29 and 72 years old. Sleep duration and sexual activities were evaluated through a self‐administered questionnaire, and total testosterone (T), sex hormone–binding globulin (SHBG), estradiol (E2), and dehydroepiandrosterone sulfate (DHEAS) were measured by established immunoassay methods in a single blood sample collected between 8:00 and 11:00 am. Bioavailable T (BioT) was calculated using the Vermeulen formula. Age was a major determinant of sleep, sex steroid hormones, and sexual activities in men. BioT, DHEAS, coital frequency, masturbation, and sleep duration declined with age. On the other hand, SHBG and E2 increased with age. Sleep duration, independently of age, aerobic exercise, and body fat, was positively associated with T and BioT, but not with DHEAS, E2, or any of the sexual activities studied. Men who masturbated had higher levels of both T and BioT. DHEAS was significantly associated with coital frequency and desire for sex. The present study showed that besides age, sleep duration was associated with androgen concentrations in men, and thus the evaluation of sleep hygiene may be beneficial in the management of men with low androgen concentrations. DHEAS may be independently associated with some sexual functions in men.
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A consistent relationship between sleep duration and testosterone has not been apparent in large cross-sectional studies of healthy community-dwelling older and young and older men.
“A consistent relationship between sleep duration and testosterone has not been apparent in large cross-sectional studies of healthy community-dwelling older [37, 38] and young and older [39] men when divided according to studies that objectively measured sleep by actigraphy (a method to infer sleep from wrist-worn devices that detect motion) or polysomnography [37] from those obtained by self-”
From Sleep, testosterone and cortisol balance, and ageing men (2022) · cites this paper as [39]
The paper describes a cross-sectional study of 531 men aged 29–72 whose sleep duration was assessed by questionnaire (p. 1; Methodologies, p. 2), so it fits the cited study category. But its Results (p. 3) find a significant positive association between sleep duration and testosterone; it does not establish that large cross-sectional studies lack a consistent relationship. (LLM, conf=0.83)
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“A consistent relationship between sleep duration and testosterone has not been apparent in large cross-sectional studies of healthy community-dwelling older [37, 38] and young and older [39] men when divided according to studies that objectively measured sleep by actigraphy (a method to infer sleep from wrist-worn dev…”
MethodLiu, P. Y. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2019-00683 · Cited by 55 · see citing works
- Authors
- Goh, V. H. ‐., & Tong, T. Y. ‐.
- Affiliations
- University of California, Los Angeles (US)
- National University of Singapore (SG)
- Corresponding author
- Goh, Victor H.‐H.
- ORCID
- Goh, Victor H.‐H.
- Venue
- Journal of Andrology
- Publisher
- Wiley
- Published
- 2010-03-04
- Volume
- 31
- Issue
- 2
- Pages
- 131-137
- ISSN
- 0196-3635 (ISSN-L)
- 1939-4640
- OpenAlex
- W2083256525
- Cited by
- 47
- References
- 34
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 2 · 2020: 2 · 2019: 4 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 5 · 2014: 3 · 2013: 5 · 2012: 5
- FWCI
- 3.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Andrology (publishedVersion)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion)
- Funders
- National Center for Research Resources (M01RR0425, M01RR000425)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Keywords
- sleep duration, sex hormones, aging, men, testosterone, bioavailable testosterone, sex hormone-binding globulin, estradiol, dehydroepiandrosterone sulfate, sexual activity, sexual frequency, masturbation, sexual desire, aerobic exercise, fat mass, sleep hygiene
- MeSH terms
- Adult, Aged, Aging, Cross-Sectional Studies, Humans, Male, Middle Aged, Surveys and Questionnaires, Sexual Behavior, Gonadal Steroid Hormones, Sleep, Asian People
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