The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Functional Characterization of Chitin and Chitosan
Abstract
Chitin and its deacetylated derivative chitosan are natural polymers composed of randomly distributed β-(1-4)- linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine (acetylated unit). Chitin is insoluble in aqueous media while chitosan is soluble in acidic conditions due to the free protonable amino groups present in the D-glucosamine units. Due to their natural origin, both chitin and chitosan can not be defined as a unique chemical structure but as a family of polymers which present a high variability in their chemical and physical properties. This variability is related not only to the origin of the samples but also to their method of preparation. Chitin and chitosan are used in fields as different as food, biomedicine and agriculture, among others. The success of chitin and chitosan in each of these specific applications is directly related to deep research into their physicochemical properties. In recent years, several reviews covering different aspects of the applications of chitin and chitosan have been published. However, these reviews have not taken into account the key role of the physicochemical properties of chitin and chitosan in their possible applications. The aim of this review is to highlight the relationship between the physicochemical properties of the polymers and their behaviour. A functional characterization of chitin and chitosan regarding some biological properties and some specific applications (drug delivery, tissue engineering, functional food, food preservative, biocatalyst immobilization, wastewater treatment, molecular imprinting and metal nanocomposites) is presented. The molecular mechanism of the biological properties such as biocompatibility, mucoadhesion, permeation enhancing effect, anticholesterolemic, and antimicrobial has been updated. Keywords: Chitin/kwd, >, chitosan, molecular weight, deacetylation degree, crystallinity, functional characterization
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Chitosan Chemistry: Relevance to the Biomedical Sciences
Muzzarelli, R. A. A., & Muzzarelli, C. (2005) · Advances in Polymer Science · doi:10.1007/b136820 · Cited by 555
Nitrate and phosphate removal by chitosan immobilized Scenedesmus
Fierro, S., del Pilar Sánchez-Saavedra, M., & Copalcúa, C. (2008) · Bioresource Technology · doi:10.1016/j.biortech.2007.02.043 · Cited by 160
Cited by
Ajmal, A., Majeed, I., Malik, R. N., Idriss, H., & Nadeem, M. A. (2014) · RSC Adv. · doi:10.1039/c4ra06658h · Cited by 1,485
Chitosan: an update on potential biomedical and pharmaceutical applications.
Cheung, R., Ng, T., Wong, J., & Chan, W. (2015) · Marine Drugs · doi:10.3390/md13085156 · Cited by 1,297
Vakili, M., Rafatullah, M., Salamatinia, B., Abdullah, A. Z., Ibrahim, M. H., Tan, K. B., Gholami, Z., & Amouzgar, P. (2014) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2014.07.007 · Cited by 1,099
Natural and synthetic polymers for wounds and burns dressing
Mogoşanu, G. D., & Grumezescu, A. M. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.12.015 · Cited by 1,052
Cellulose-based hydrogel materials: chemistry, properties and their prospective applications
Kabir, S. M. F., Sikdar, P. P., Haque, B., Bhuiyan, M. A. R., Ali, A., & Islam, M. N. (2018) · Progress in Biomaterials · doi:10.1007/s40204-018-0095-0 · Cited by 565
Seafood waste: a source for preparation of commercially employable chitin/chitosan materials
Yadav, M., Goswami, P., Paritosh, K., Kumar, M., Pareek, N., & Vivekanand, V. (2019) · Bioresources and Bioprocessing · doi:10.1186/s40643-019-0243-y · Cited by 515
Microencapsulation with chitosan by spray drying for industry applications – A review
Estevinho, B. N., Rocha, F., Santos, L., & Alves, A. (2013) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2013.04.001 · Cited by 391
Smets, R., Verbinnen, B., Van De Voorde, I., Aerts, G., Claes, J., & Van Der Borght, M. (2020) · Waste and Biomass Valorization · doi:10.1007/s12649-019-00924-2 · Cited by 162
Interaction Between Chitosan and Mucin: Fundamentals and Applications
Collado-González, M., González Espinosa, Y., & Goycoolea, F. M. (2019) · Biomimetics · doi:10.3390/biomimetics4020032 · Cited by 160
Anitha, A., Deepa, N., Chennazhi, K. P., Lakshmanan, V.-K., & Jayakumar, R. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.06.004 · Cited by 158
Antibacterial cotton fibers treated with silver nanoparticles and quaternary ammonium salts
Kang, C. K., Kim, S. S., Kim, S., Lee, J., Lee, J.-H., Roh, C., & Lee, J. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2016.06.043 · Cited by 127
Particulate formulations based on chitosan for nose-to-brain delivery of drugs. A review
Rassu, G., Soddu, E., Cossu, M., Gavini, E., Giunchedi, P., & Dalpiaz, A. (2016) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2015.05.002 · Cited by 87
Bioactive Compounds from Hermetia Illucens Larvae as Natural Ingredients for Cosmetic Application
Almeida, C., Rijo, P., & Rosado, C. (2020) · Biomolecules · doi:10.3390/biom10070976 · Cited by 81
Chitin and Chitosans: Characteristics, Eco-Friendly Processes and Applications in Cosmetic Science
Casadidio, C., Vargas Peregrina, D., Gigliobianco, M. R., Deng, S., Censi, R., & Di Martino, P. (2019) · doi:10.20944/preprints201905.0066.v1 · Cited by 350
Mendes, A. C., Sevilla Moreno, J., Hanif, M., E.L. Douglas, T., Chen, M., & Chronakis, I. S. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19082266 · Cited by 55
The bioengineered cardiac left ventricle
Patel, N. M., & Birla, R. K. (2018) · ASAIO Journal · doi:10.1097/mat.0000000000000642 · Cited by 20
Metadata
- Authors
- Aranaz, I., Mengibar, M., Harris, R., Panos, I., Miralles, B., Acosta, N., Galed, G., & Heras, A.
- Venue
- Current Chemical Biology
- Publisher
- Bentham Science Publishers Ltd.
- Published
- 2009-05-01
- Volume
- 3
- Issue
- 2
- Pages
- 203-230
- ISSN
- 1872-3136 (ISSN-L)
- OpenAlex
- W2025286606
- Cited by
- 1,214
- References
- 3
- FWCI
- 16.00
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
