Particulate formulations based on chitosan for nose-to-brain delivery of drugs. A review

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Chitosan alleviates symptoms of Parkinson’s disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood–brain barrier

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Intranasal Therapeutics for Neurodegenerative Disorders: Overcoming the Blood–Brain Barrier with Smart Formulations and Devices

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Chitosan-based nanocomposites for gene delivery: Application and future perspectives

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Nanotechnological approaches for efficient N2B delivery: from small-molecule drugs to biopharmaceuticals

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Development of thiolated polyethylene glycol-poly (lactic-co-glycolic acid) co-polymeric nanoparticles for intranasal delivery of quetiapine: in vitro–ex vivo characterization

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Spray Dried Levodopa-Doped Powder Potentially for Intranasal Delivery

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Nose to brain delivery of insulin loaded in PLGA and chitosan-coated PLGA nanoparticles: A promising approach for Alzheimer's disease therapy

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Intranasal gene therapy for the treatment of neurological disorders

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Nanocarrier Mediated Intranasal Drug Delivery Systems for the Management of Parkinsonism: A Review

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Development of Nanocomposite Microspheres for Nasal Administration of Deferiprone in Neurodegenerative Disorders

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Development and Characterization of Levodopa Loaded Pharmacosomes for Brain Targeting via Intranasal Route: Pharmacodynamic Evaluation in Rats

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Intranasal delivery of sulpiride nanostructured lipid carrier to central nervous system; in vitro characterization and in vivo study

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Intranasal Delivery of Lipid Nanoparticles: A Ground-breaking Approach for Brain Targeting

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Factors Affecting the Design of Nasal Drug Delivery System

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Tamarind seed polymer-based formulations: advances and applications in biomedical science

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Biomedical applications of biopolymer-based (nano)materials

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Overview of chitosan-based nanosystems for prostate cancer therapy

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Chitosan-based nanoparticles for the treatment of neurological disorders

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Surface Modification of Solid Lipid Nanoparticles: Enhancements in Drug Delivery and Treatment Efficacy

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Potential Biomedical Applications of Marine Sponge-Derived Chitosan: Current Breakthroughs in Drug Delivery for Wound Care

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Nose

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Nose-to-Brain Drug Delivery Strategies for the Treatment of Neurological Disorders

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Controlled Drug Delivery via the Nasal Route

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Peptide drugs for obesity and type 2 diabetes mellitus: an overview of clinical trials

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Nanomedicines for CNS therapy: Fundamental aspects

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Recouvrement et modification de nanoparticules afin d’optimiser leurs propriétés physico-chimiques pour des applications pharmaceutiques

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Hydrogel in brain targeting

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Spray-dried L-Cysteine Chitosan microparticles enable prolonged intranasal delivery of Donepezil

Lelio, B. D., Topalian, R., Brenner, I., Rau, I. A., Stoll, R., Rosenau, F., Tovar, G. E. M., Gruber‐Traub, C., & Mavoungou, C. (2026) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2026.108750

Chitosan-Based Nose-to-Brain Drug Delivery for Management of Neurological Disorders: Intrinsic Neuroprotective Action and Carrier Capabilities

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Spray-dried chitosan particles as controlled intranasal drug delivery systems with high encapsulation efficiency for small molecules and monoclonal antibodies

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Chitosan in nasal delivery systems for therapeutic drugs

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Chitosan nanoparticles for nasal drug delivery

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Recent Advancements in the Chitosan‐Decorated Nasal Drug Delivery Systems: Biopharmaceutical Characteristics, Patent Reports, and Clinical Trials

Hafeez, A. (2026) · Starch - Stärke · doi:10.1002/star.70256

Chitosan-coated solid lipid nanoparticles for nose-to-brain drug delivery: A comprehensive review

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Chitosan-Based Nanoparticles for Nose-to-Brain Drug Delivery: A Real Path toward Effective CNS Therapy?

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