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Cited by 400

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Immunomodulatory Effects of Probiotics in the Intestinal Tract

Open access
·2008·Current Issues in Molecular Biology

Abstract

The intestinal microbiota is the largest source of microbial stimulation that exerts both harmful and beneficial effects on human health. The interaction between probiotic and enterocytes is the initiating event in immunomodulation and merits particular attention. The effects of probiotic is strain dependent and for each new probiotic strain, profiles of cytokines secreted by lymphocytes, enterocytes or dendritic cells that come in contact with the strain should be systematically established. To evaluate the effects of probiotics on the immune system, models that mimic the mucosa, and thus the physiological reality, should be preferred whenever it is possible. Then, the in vitro observed effects should be backed up by properly conducted randomized double bind clinical studies. More detailed studies are needed to determine the precise action mode of probiotics on both mucosal and systemic immunity.

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Registry

Crossref · 10.21775/cimb.010.037

Cites

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Metadata

Venue
Current Issues in Molecular Biology
Publisher
MDPI AG
Published
2008
Volume
10
Issue
1-2
Pages
37-54
ISSN
1467-3037 (ISSN-L)
OpenAlex
W60937635
Cited by
400
References
10
FWCI
35.12
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Immunomodulatory Effects of Probiotics in the Intestinal Tract. https://app.cochat.ai/papers/10.21775/cimb.010.037
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Immunomodulatory Effects of Probiotics in the Intestinal Tract. (2008). Current Issues in Molecular Biology. https://doi.org/10.21775/cimb.010.037

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.