Cited by 181Mobile Health and mHealth ApplicationsDiabetes Management and EducationDigital Mental Health Interventions

Effectiveness of mobile app-assisted self-care interventions for improving patient outcomes in type 2 diabetes and/or hypertension: systematic review and meta-analysis of randomized controlled trials

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Liu, Kaifeng, Xie, Zhenzhen, Or, Calvin Kalun·2020·JMIR mHealth and uHealth

Published version of a preprint

Abstract

BACKGROUND: Mobile app-assisted self-care interventions are emerging promising tools to support self-care of patients with chronic diseases such as type 2 diabetes and hypertension. The effectiveness of such interventions requires further exploration for more supporting evidence. OBJECTIVE: A systematic review and meta-analysis of randomized controlled trials (RCTs) were conducted to examine the effectiveness of mobile app-assisted self-care interventions developed for type 2 diabetes and/or hypertension in improving patient outcomes. METHODS: ) levels, systolic blood pressure (SBP), and diastolic blood pressure (DBP). Changes in other clinical-, behavioral-, knowledge-, and psychosocial-related outcomes were included as secondary outcomes. Primary outcomes and objective secondary outcomes that were reported in at least two trials were meta-analyzed; otherwise, a narrative synthesis was used for data analysis. RESULTS: levels (standardized mean difference [SMD] -0.44, 95% CI -0.59 to -0.29; P<.001), SBP (SMD -0.17, 95% CI -0.31 to -0.03, P=.02), and DBP (SMD -0.17, 95% CI -0.30 to -0.03, P=.02). Subgroup analyses for primary outcomes showed that several intervention features were supportive of self-management, including blood glucose, blood pressure, and medication monitoring, communication with health care providers, automated feedback, personalized goal setting, reminders, education materials, and data visualization. In addition, 8 objective secondary outcomes were meta-analyzed, which showed that the interventions had significant lowering effects on fasting blood glucose levels and waist circumference. A total of 42 secondary outcomes were narratively synthesized, and mixed results were found. CONCLUSIONS: Mobile app-assisted self-care interventions can be effective tools for managing blood glucose and blood pressure, likely because their use facilitates remote management of health issues and data, provision of personalized self-care recommendations, patient-care provider communication, and decision making. More studies are required to further determine which combinations of intervention features are most effective in improving the control of the diseases. Moreover, evidence regarding the effects of these interventions on the behavioral, knowledge, and psychosocial outcomes of patients is still scarce, which warrants further examination.

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  1. [20]Higgins JPT Green S Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0 2011 Hoboken John Wiley & Sons
  2. [66]Shneiderman B Plaisant C Designing the User Interfaces: Strategies for Effective Human-Computer Interaction 2010 New York Pearson Education

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Authors
Liu, K., Xie, Z., & Or, C. K.
Affiliations
University of Hong Kong (HK)
Corresponding author
Or, Calvin Kalun
Venue
JMIR mHealth and uHealth
Published
2020-08-04
Volume
8
Issue
8
Pages
e15779
ISSN
2291-5222 (ISSN-L)
OpenAlex
W3021141263
Cited by
181
References
69
Citations by year
2026: 20 · 2025: 29 · 2024: 39 · 2023: 40 · 2022: 34 · 2021: 14 · 2020: 4
FWCI
4.40
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • JMIR mhealth and uhealth (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
University of Hong Kong
Topics
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
Keywords
mobile health apps, self-care interventions, type 2 diabetes, hypertension, glycemic control, blood pressure control, chronic disease self-management, medication adherence, automated feedback, personalized goal setting, remote patient monitoring, patient-provider communication, waist circumference
MeSH terms
Diabetes Mellitus, Type 2, Humans, Hypertension, Self Care, Randomized Controlled Trials as Topic, Mobile Applications

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