The Effect of Reminiscence Therapy Using Virtual Reality on Apathy in Residential Aged Care: Multisite Nonrandomized Controlled Trial
Open accessPublished version of a preprint
Abstract
Background: Apathy is a frequent and underrecognized neurological disorder symptom. Reduced goal-directed behavior caused by apathy is associated with poor outcomes for older adults in residential aged care. Recommended nonpharmacological treatments include person-centered therapy using information and communication technology. Virtual reality (VR) in the form of head-mounted displays (HMDs) is a fully immersive technology that provides access to a wide range of freely available content. The use of VR as a therapy tool has demonstrated promise in the treatment of posttraumatic stress disorder and anxiety. In addition, VR has been used to improve conditions including depression, anxiety, cognitive function, and balance in older adults with memory deficits, Alzheimer disease, and Parkinson disease. Research using VR for the symptoms of apathy in older adults living in residential aged care facilities is limited. Objective: This study aims to examine whether using HMDs as a tool for reminiscence therapy improves the symptoms of apathy compared with using a laptop computer and physical items with older adults living in residential aged care. Methods: In this multisite trial, 43 participants were allocated to one of three groups: reminiscence therapy intervention using VR in the form of HMDs, reminiscence therapy using a laptop computer supplemented by physical items if required (active control), and a usual care (passive control) group. The primary outcome was apathy, and the secondary outcomes included cognition and depression. The side effects of using HMDs were also measured in the VR group. Results: Mixed model analyses revealed no significant group interaction over time in outcomes between the VR and laptop groups (estimate=−2.24, SE 1.89; t40=−1.18; P=.24). Pooled apathy scores in the two intervention groups compared with the passive control group also revealed no significant group interaction over time (estimate=−0.26, SE 1.66; t40=−0.16; P=.88). There were no significant secondary outcomes. Most participants in the VR group stated that they would prefer to watch content in VR than on a flat screen (Χ22=11.2; P=.004), side effects from HMD use were negligible to minimal according to the Simulator Sickness Questionnaire cutoff scores. Conclusions: Although there were no significant results in outcome measures, this study found that participants engaged in the research and enjoyed the process of reminiscing using both forms of technology. It was found that VR can be implemented in an aged care setting with correct protocols in place. Providing residents in aged care with a choice of technology may assist in increasing participation in activities. We cannot dismiss the importance of immediate effects while the therapy was in progress, and this is an avenue for future research. Trial Registration: Australian New Zealand Clinical Trials Registry ACTRN12619001510134; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=378564. International Registered Report Identifier (IRRID): RR2-DOI: 10.1136/bmjopen-2020-046030
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The preparation of tailored VR content can be labor-intensive and time-consuming.
“The preparation of tailored VR content can be labor-intensive and time-consuming (Saredakis et al., 2021).”
From Facilitators and Barriers to Using Virtual Reality and its Impact on Social Engagement in Aged Care Settings: A Scoping Review (2023) · cites this paper as Saredakis et al., 2021
Methods > Procedure (page unavailable) reports that a researcher spent approximately 60 minutes interviewing each participant to establish topics for personalized reminiscence sessions. This supports a time commitment to tailoring the sessions, but the paper does not say that preparing the VR content itself was labor-intensive or time-consuming. Discussion > Content (page unavailable) says the content could be sourced through readily available apps. (LLM, conf=0.76)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Harris, P. A., Taylor, R., Thielke, R., Payne, J., Gonzalez, N., & Conde, J. G. (2009) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2008.08.010 · Cited by 51,384 · see citing works
Moher, D., Hopewell, S., Schulz, K. F., Montori, V., Gotzsche, P. C., Devereaux, P. J., Elbourne, D., Egger, M., & Altman, D. G. (2010) · BMJ · doi:10.1136/bmj.c869 · Cited by 8,883 · see citing works
Sheikh (1986) · doi:10.1300/j018v05n01_09 · Cited by 7,236 · see citing works
Simulator Sickness Questionnaire: An Enhanced Method for Quantifying Simulator Sickness
Kennedy, R. S., Lane, N. E., Berbaum, K. S., & Lilienthal, M. G. (1993) · The International Journal of Aviation Psychology · doi:10.1207/s15327108ijap0303_3 · Cited by 5,457 · see citing works
A Short Scale for Measuring Loneliness in Large Surveys: Results From Two Population-Based Studies
Hughes, M. E., Waite, L. J., Hawkley, L. C., & Cacioppo, J. T. (2004) · Research on Aging · doi:10.1177/0164027504268574 · Cited by 4,781 · see citing works
Moher, D., Hopewell, S., Schulz, K. F., Montori, V., Gøtzsche, P. C., Devereaux, P. J., Elbourne, D., Egger, M., & Altman, D. G. (2012) · International Journal of Surgery · doi:10.1016/j.ijsu.2011.10.001 · Cited by 2,345 · see citing works
Reliability and validity of the apathy evaluation scale
Marin, R. S., Biedrzycki, R. C., & Firinciogullari, S. (1991) · Psychiatry Research · doi:10.1016/0165-1781(91)90040-v · Cited by 1,805 · see citing works
How Immersive Is Enough? A Meta-Analysis of the Effect of Immersive Technology on User Presence
Cummings, J. J., & Bailenson, J. N. (2016) · Media Psychology · doi:10.1080/15213269.2015.1015740 · Cited by 1,749 · see citing works
Assessing Quality of Life in Older Adults With Cognitive Impairment
Logsdon, R. G., Gibbons, L. E., McCurry, S. M., & Teri, L. (2002) · Psychosomatic Medicine · doi:10.1097/00006842-200205000-00016 · Cited by 1,381 · see citing works
Review on cybersickness in applications and visual displays
Rebenitsch, L., & Owen, C. (2016) · Virtual Reality · doi:10.1007/s10055-016-0285-9 · Cited by 971 · see citing works
Hsieh, S., Schubert, S., Hoon, C., Mioshi, E., & Hodges, J. R. (2013) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000351671 · Cited by 970 · see citing works
Reminiscence therapy for dementia
Woods, B. T., O’Philbin, L., Farrell, E. M., Spector, A. E., & Orrell, M. W. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001120.pub3 · Cited by 880 · see citing works
The Factor Structure of the Presence Questionnaire
Witmer, B. G., Jerome, C. J., & Singer, M. J. (2005) · Presence: Teleoperators and Virtual Environments · doi:10.1162/105474605323384654 · Cited by 770 · see citing works
D'Ath, P., Katona, P., Mullan, E., Evans, S., & Katona, C. (1994) · Family Practice · doi:10.1093/fampra/11.3.260 · Cited by 659 · see citing works
Virtual memory palaces: immersion aids recall
Krokos, E., Catherine Plaisant, B., & Varshney, A. (2018) · Virtual Reality · doi:10.1007/s10055-018-0346-3 · Cited by 610 · see citing works
Strohminger, N., & Nichols, S. (2014) · Cognition · doi:10.1016/j.cognition.2013.12.005 · Cited by 596 · see citing works
Sockeel, P. (2006) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2005.075929 · Cited by 512 · see citing works
Autobiographical memory: Exploring its functions in everyday life
Bluck, S. (2003) · Memory · doi:10.1080/741938206 · Cited by 495 · see citing works
Whose Quality of Life Is It Anyway?
Thorgrimsen, L., Selwood, A., Spector, A. E., Royan, L., Lopez, M. D. M., Woods, B. T., & Orrell, M. W. (2003) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-200310000-00002 · Cited by 454 · see citing works
Effects of reminiscence interventions on psychosocial outcomes: A meta-analysis
Pinquart, M., & Forstmeier, S. (2012) · Aging & Mental Health · doi:10.1080/13607863.2011.651434 · Cited by 407 · see citing works
Difede, J., & Cukor, J. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v68n1102 · Cited by 357 · see citing works
What types of reminiscence are associated with successful aging?
Wong, P. T. P., & Watt, L. (1991) · Psychology and Aging · doi:10.1037//0882-7974.6.2.272 · Cited by 332 · see citing works
Optale, G., Urgesi, C., Busato, V., Marin, S., Piron, L., Priftis, K., Gamberini, L., Capodieci, S., & Bordin, A. (2010) · Neurorehabilitation and Neural Repair · doi:10.1177/1545968309353328 · Cited by 318 · see citing works
Negative symptoms: the ‘pathology’ of motivation and goal-directed behaviour
Brown, R. G., & Pluck, G. C. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01626-x · Cited by 297 · see citing works
Robert, P., Lanctôt, K., Agüera-Ortiz, L., Aalten, P., Brémond, F., Defrancesco, M., Hanon, C., David, R., Dubois, B., Dujardin, K., et al. (2018) · European psychiatry · doi:10.1016/j.eurpsy.2018.07.008 · Cited by 283 · see citing works
Baldwin, S. A., Berkeljon, A., Atkins, D. C., Olsen, J. A., & Nielsen, S. L. (2009) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0015235 · Cited by 274 · see citing works
Selbæk, G., Engedal, K., & Bergh, S. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.09.027 · Cited by 271 · see citing works
The Neuropsychology of Emotion.
Cimino, C. R. (2002) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200201000-00016 · Cited by 270 · see citing works
Yeo, N. L., White, M. P., Alcock, I., Garside, R., Dean, S. G., Smalley, A. J., & Gatersleben, B. (2020) · Journal of Environmental Psychology · doi:10.1016/j.jenvp.2020.101500 · Cited by 260 · see citing works
Randomization in Clinical Trials: Permuted Blocks and Stratification
Broglio, K. (2018) · JAMA · doi:10.1001/jama.2018.6360 · Cited by 243 · see citing works
Clinical Virtual Reality tools to advance the prevention, assessment, and treatment of PTSD
Rizzo, A. ‘., & Shilling, R. (2017) · European Journal of Psychotraumatology · doi:10.1080/20008198.2017.1414560 · Cited by 241 · see citing works
Spiegel, B., Fuller, G., Lopez, M., Dupuy, T., Noah, B., Howard, A., Albert, M., Tashjian, V., Lam, R., Ahn, J., et al. (2019) · PLOS ONE · doi:10.1371/journal.pone.0219115 · Cited by 233 · see citing works
Apathy associated with neurocognitive disorders: Recent progress and future directions
Lanctôt, K. L., Agüera-Ortíz, L., Brodaty, H., Francis, P. T., Geda, Y. E., Ismail, Z., Marshall, G. A., Mortby, M. E., Onyike, C. U., Padala, P. R., et al. (2016) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2016.05.008 · Cited by 222 · see citing works
A Systematic Review of the Use of Technology for Reminiscence Therapy
Lazar, A., Thompson, H. J., & Demiris, G. (2014) · Health Education & Behavior · doi:10.1177/1090198114537067 · Cited by 218 · see citing works
Dermody, G., Whitehead, L., Wilson, G., & Glass, C. (2020) · Journal of Medical Internet Research · doi:10.2196/17331 · Cited by 209 · see citing works
Gardiner, C., Laud, P., Heaton, T., & Gott, M. (2020) · Age and Ageing · doi:10.1093/ageing/afaa049 · Cited by 204 · see citing works
Lara, B., Carnes, A., Dakterzada, F., Benitez, I., & Piñol‐Ripoll, G. (2020) · European Journal of Neurology · doi:10.1111/ene.14339 · Cited by 197 · see citing works
Prevalence and Predictors of Neuropsychiatric Symptoms in Cognitively Impaired Nursing Home Patients
Zuidema, S. U., Koopmans, R. T. C. M., & Verhey, F. R. J. (2007) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988706292762 · Cited by 197 · see citing works
Mapping the Future of Reminiscence: A Conceptual Guide for Research and Practice
Webster, J., Bohlmeijer, E., & Westerhof, G. (2010) · Research on Aging · doi:10.1177/0164027510364122 · Cited by 195 · see citing works
Handbook of Virtual Environments
Hale, K. S., & Stanney, K. M. (2014) · CRC Press eBooks · doi:10.1201/b17360 · Cited by 193 · see citing works
Ballard, C. G., O'Brien, J. T., James, I. A., Mynt, P., Lana, M. M., Potkins, D., Reichelt, K., Lee, L., Swann, A., & Fossey, J. (2001) · International Psychogeriatrics · doi:10.1017/s1041610201007499 · Cited by 173 · see citing works
Steinhauser, K. E., Alexander, S. C., Byock, I. R., George, L. K., Olsen, M. K., & Tulsky, J. A. (2008) · Journal of Palliative Medicine · doi:10.1089/jpm.2008.0078 · Cited by 172 · see citing works
Nonpharmacological Management of Apathy in Dementia: A Systematic Review
Brodaty, H., & Burns, K. A. (2011) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31822be242 · Cited by 164 · see citing works
Challenges of conducting research in long-term care facilities: a systematic review
Lam, H. R., Chow, S. L.-M., Taylor, K., Chow, R., Lam, H., Bonin, K., Rowbottom, L., & Herrmann, N. (2018) · BMC Geriatrics · doi:10.1186/s12877-018-0934-9 · Cited by 158 · see citing works
Experiences in Virtual Reality: a Window to Autobiographical Memory
Schöne, B., Wessels, M., & Gruber, T. (2017) · Current Psychology · doi:10.1007/s12144-017-9648-y · Cited by 153 · see citing works
Jorm, A. F., Mackinnon, A. J., Henderson, A. S., Scott, R., Christensen, H. M., Korten, A. E., Cullen, J. S., & Mulligan, R. (1995) · Psychological Medicine · doi:10.1017/s0033291700033377 · Cited by 149 · see citing works
A systematic review and meta-analysis on the effect of reminiscence therapy for people with dementia
Park, K., Lee, S., 양정은, Song, T., & Hong, G. S. (2019) · International Psychogeriatrics · doi:10.1017/s1041610218002168 · Cited by 144 · see citing works
An Art Gallery Access Programme for people with dementia: ‘You do it for the moment’
MacPherson, S., Bird, M., Anderson, K., Davis, T., & Blair, A. C. (2009) · Aging & Mental Health · doi:10.1080/13607860902918207 · Cited by 138 · see citing works
Apathy in Dementia: An Examination of the Psychometric Properties of the Apathy Evaluation Scale
Clarke, D. E., van Reekum, R., Simard, M., Streiner, D. L., Freedman, M., & Conn, D. K. (2007) · Journal of Neuropsychiatry · doi:10.1176/jnp.2007.19.1.57 · Cited by 133 · see citing works
Association of Apathy With Risk of Incident Dementia
van Dalen, J. W., van Wanrooij, L. L., van Charante, E. P. M., Brayne, C., van Gool, W. A., & Richard, E. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.1877 · Cited by 133 · see citing works
Neurodegeneration and chronic renal failure in methylmalonic aciduria—A pathophysiological approach
Morath, M., Okun, J. G., Müller, I., Sauer, S. W., Hörster, F., Hoffmann, G. F., & Kölker, S. (2007) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-007-0571-5 · Cited by 130 · see citing works
Surr, C. (2005) · Social Science & Medicine · doi:10.1016/j.socscimed.2005.08.025 · Cited by 127 · see citing works
Kverno, K. S., Black, B. S., Nolan, M. T., & Rabins, P. V. (2009) · International Psychogeriatrics · doi:10.1017/s1041610209990196 · Cited by 126 · see citing works
Addenbrooke’s Cognitive Examination-III
Noone, P. A. (2015) · Occupational Medicine · doi:10.1093/occmed/kqv041 · Cited by 119 · see citing works
Con.gural Scoring of Simulator Sickness, Cybersickness and Space Adaptation Syndrome
Stanney, K. M., Kennedy, R. S., Harm, D. L., Compton, D. E., Lanham, D. S., & Drexler, J. M. (2003) · CRC Press eBooks · doi:10.1201/9781410608888.ch12 · Cited by 113 · see citing works
Pharmacological interventions for apathy in Alzheimer's disease
Ruthirakuhan, M. T., Herrmann, N., Abraham, E. H., Chan, S., & Lanctôt, K. L. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012197.pub2 · Cited by 113 · see citing works
Harmand, M. G., Meillon, C., Rullier, L., Ávila‐Funes, J. A., Bergua, V., Dartigues, J., & Amieva, H. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2014.02.006 · Cited by 112 · see citing works
Sluggett, J. K., Ilomäki, J., Seaman, K. L., Corlis, M. E., & Bell, J. S. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.12.011 · Cited by 109 · see citing works
Self-citationThe Geriatric Depression Scale (GDS)
Kurlowicz, L. H., & Greenberg, S. A. (2007) · AJN American Journal of Nursing · doi:10.1097/01.naj.0000292207.37066.2f · Cited by 106 · see citing works
Preliminary Research: Virtual Reality in Residential Aged Care to Reduce Apathy and Improve Mood
Brimelow, R. E., Dawe, B., & Dissanayaka, N. N. (2019) · Cyberpsychology Behavior and Social Networking · doi:10.1089/cyber.2019.0286 · Cited by 100 · see citing works
Beyond Feeling Sick: The Visual and Cognitive Aftereffects of Virtual Reality
Szpak, A., Michalski, S. C., Saredakis, D., Chen, C. S., & Loetscher, T. (2019) · IEEE Access · doi:10.1109/access.2019.2940073 · Cited by 97 · see citing works
Self-citationBaillon, S. F., van Diepen, E., Prettyman, R. J., Redman, J., Rooke, N., & Campbell, R. (2004) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1208 · Cited by 97 · see citing works
Reminiscence therapy for older adults with Alzheimer's disease: A literature review
Cuevas, P. E. G., Davidson, P. M., Mejilla, J. L., & Rodney, T. W. (2020) · International Journal of Mental Health Nursing · doi:10.1111/inm.12692 · Cited by 94 · see citing works
Kumfor, F., Zhen, A., Hodges, J. R., Piguet, O., & Irish, M. (2018) · Cortex · doi:10.1016/j.cortex.2018.03.019 · Cited by 92 · see citing works
Immersive Virtual Reality for the Management of Pain in Community-Dwelling Older Adults
Benham, S., Kang, M., & Grampurohit, N. (2018) · OTJR Occupational Therapy Journal of Research · doi:10.1177/1539449218817291 · Cited by 89 · see citing works
Virtual Reality Applications for Neurological Disease: A Review
Schiza, E. C., Matsangidou, M., Neokleous, K., & Pattichis, C. S. (2019) · Frontiers in Robotics and AI · doi:10.3389/frobt.2019.00100 · Cited by 88 · see citing works
Functions of reminiscence and emotional regulation among older adults
Cappeliez, P., Guindon, M., & Robitaille, A. (2008) · Journal of Aging Studies · doi:10.1016/j.jaging.2007.06.003 · Cited by 87 · see citing works
Virtual and Adaptive Environments: Applications, Implications, and Human Performance Issues
Ruddle, R. A. (2004) · PRESENCE Virtual and Augmented Reality · doi:10.1162/1054746041944821 · Cited by 87 · see citing works
CAVE: An Emerging Immersive Technology -- A Review
Manjrekar, S., Sandilya, S., Bhosale, D., Kanchi, S., Pitkar, A., & Gondhalekar, M. (2014) · UKSim International Conference on Computer Modelling and Simulation (UKSim) · doi:10.1109/uksim.2014.20 · Cited by 84 · see citing works
Using Virtual Reality to Improve Apathy in Residential Aged Care: Mixed Methods Study
Saredakis, D., Keage, H. A., Corlis, M., & Loetscher, T. (2020) · Journal of Medical Internet Research · doi:10.2196/17632 · Cited by 82 · see citing works
Self-citationA systematic review of non‐pharmacological treatments for apathy in dementia
Theleritis, C. G., Siarkos, K., Politis, A. A., Katirtzoglou, E. A., & Politis, A. M. (2017) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4783 · Cited by 81 · see citing works
Promoting Reminiscences with Virtual Reality Headsets: A Pilot Study with People with Dementia
Coelho, T., Marques, C., Moreira, D., Soares, M., Portugal, P., Marques, A., Ferreira, A. R., Martins, S., & Fernandes, L. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17249301 · Cited by 79 · see citing works
Høeg, E. R., Povlsen, T. M., Bruun‐Pedersen, J. R., Lange, B. S., Nilsson, N. C., Haugaard, K. B., Faber, S. M., Hansen, S. W., Kimby, C. K., & Serafin, S. (2021) · Frontiers in Virtual Reality · doi:10.3389/frvir.2021.647993 · Cited by 79 · see citing works
Hsieh, C., Chang, C., Su, S., Hsiao, Y.-L., Shih, Y.-W., Han, W.-H., & Lin, C. (2010) · Journal of Experimental & Clinical Medicine · doi:10.1016/s1878-3317(10)60012-5 · Cited by 72 · see citing works
Fear of falling: efficacy of virtual reality associated with serious games in elderly people
Levy, F., Rautureau, G., Komano, O., Millet, B., Jouvent, R., & Leboucher, P. (2016) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s97809 · Cited by 72 · see citing works
The Handbook of Structured Life Review
Gingerich, B. S. (2008) · Home Health Care Management & Practice · doi:10.1177/1084822308326042 · Cited by 70 · see citing works
Davis, M. C. (2004) · Issues in Mental Health Nursing · doi:10.1080/01612840490443455 · Cited by 57 · see citing works
Apathy: Risk Factor for Mortality in Nursing Home Patients
Nijsten, J. M. H., Leontjevas, R., Pat‐El, R., Smalbrugge, M., Koopmans, R. T. C. M., & Gerritsen, D. L. (2017) · Journal of the American Geriatrics Society · doi:10.1111/jgs.15007 · Cited by 57 · see citing works
Manav, A. İ., & Şimşek, N. (2019) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988718819864 · Cited by 55 · see citing works
Bharathi, A. K. B. G., & Tucker, C. S. (2015) · ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference (IDETC/CIE) · doi:10.1115/detc2015-47388 · Cited by 52 · see citing works
Chan, J. Y. C., Chan, T. K., Wong, M. P. F., Cheung, R. S. M., Yiu, K. K. L., & Tsoi, K. K. F. (2020) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5314 · Cited by 50 · see citing works
Clinical practice guidelines and principles of care for people with dementia in Australia.
Dyer, S. M., Laver, K., Pond, C. D., Cumming, R. G., Whitehead, C., & Crotty, M. (2016) · PubMed · Cited by 47 · see citing works
OKUMURA, Y., Tanimukai, S., & Asada, T. (2008) · Psychogeriatrics · doi:10.1111/j.1479-8301.2008.00236.x · Cited by 45 · see citing works
Bruun-Pedersen, J. R., Serafin, S., & Kofoed, L. B. (2016) · 2016 IEEE International Conference on Healthcare Informatics (ICHI) · doi:10.1109/ichi.2016.31 · Cited by 40 · see citing works
Netz, Y., Lidor, R., & Ziv, G. (2019) · European Review of Aging and Physical Activity · doi:10.1186/s11556-019-0224-3 · Cited by 31 · see citing works
Pharmacologic Approaches for the Management of Apathy in Neurodegenerative Disorders
Bogdan, A., Manera, V., König, A., & David, R. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01581 · Cited by 29 · see citing works
Penteado, C. T., Loureiro, J. C., Pais, M. V., Carvalho, C. L., Sant’Ana, L. C. F. G., Valiengo, L. D. C. L., Stella, F., & Forlenza, O. V. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.578672 · Cited by 27 · see citing works
Virtual visits: Reminiscence in residential aged care with digital mapping technologies
Webber, S., Baker, S., & Waycott, J. (2021) · Australasian Journal on Ageing · doi:10.1111/ajag.12902 · Cited by 27 · see citing works
Computer-assisted reminiscence therapy: developing practice
Pringle, A., & Somerville, S. (2013) · Mental Health Practice · doi:10.7748/mhp2013.12.17.4.34.e830 · Cited by 23 · see citing works
Unmet Needs in Pharmacological Treatment of Apathy in Alzheimer’s Disease: A Systematic Review
Theleritis, C., Siarkos, K., & Politis, A. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01108 · Cited by 18 · see citing works
Saredakis, D., Keage, H. A. D., Corlis, M. E., & Loetscher, T. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-046030 · Cited by 14 · see citing works
Self-citationHuman Aspects of IT for the Aged Population. Applications in Health, Assistance, and Entertainment
(2018) · Lecture notes in computer science · doi:10.1007/978-3-319-92037-5 · Cited by 10 · see citing works
(2003) · Oxford Art Online · doi:10.1093/gao/9781884446054.article.t063204 · Cited by 7 · see citing works
Reminiscence Cognitive Behavior Therapy for Spiritual Well-Being and Self-Esteem of Cancer Patients
Ando, M., Morita, T., & Oshima, A. (2011) · Journal of Cancer Therapy · doi:10.4236/jct.2011.22012 · Cited by 4 · see citing works
Chatterton, C. (2012) · Nursing Older People · doi:10.7748/nop.24.1.8.s2 · Cited by 3 · see citing works
van Reekum, R., & van Reekum, E. A. (2013) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781585625154.da11 · Cited by 1 · see citing works
THE HANDBOOK OF STRUCTURED LIFE REVIEW By Barbara K. Haight and Barrett S. Haight
Brady, E. M. (2008) · Educational Gerontology · doi:10.1080/03601270802505574 · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Wu, Y., Wang, N., Zhang, H., Sun, X., Wang, Y., & Zhang, Y. (2023) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2023.01.023 · Cited by 68 · see citing works
Restout, J., Bernache‐Assollant, I., Morizio, C., Boujut, A., Angelini, L., Tchalla, A. E., & Perrochon, A. (2023) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2022.12.026 · Cited by 54 · see citing works
Hung, L., Mann, J., Wallsworth, C., Upreti, M., Kan, W., Temirova, A., Wong, K. L. Y., Ren, H., To-Miles, F., Wong, J., et al. (2023) · Gerontology and Geriatric Medicine · doi:10.1177/23337214231166355 · Cited by 48 · see citing works
“The preparation of tailored VR content can be labor-intensive and time-consuming (Saredakis et al., 2021).”
BackgroundMao, Q., Zhao, Z., Yu, L., Zhao, Y., & Wang, H. (2024) · Journal of Medical Internet Research · doi:10.2196/53348 · Cited by 46 · see citing works
Virtual Reality in Palliative Care: A Systematic Review
Martin, J. L., Saredakis, D., Hutchinson, A. D., Crawford, G. B., & Loetscher, T. (2022) · Healthcare · doi:10.3390/healthcare10071222 · Cited by 43 · see citing works
Self-citationAn Update on Apathy in Alzheimer’s Disease
Dolphin, H., Dyer, A. H., McHale, C., O’Dowd, S., & Kennelly, S. (2023) · Geriatrics · doi:10.3390/geriatrics8040075 · Cited by 34 · see citing works
Li, G., Li, X., & Chen, L. (2022) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2022.104378 · Cited by 34 · see citing works
Xu, L., Li, S., Yan, R., Ni, Y., Wang, Y., & Li, Y. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1139700 · Cited by 31 · see citing works
Ng, W. H. D., Ang, W. H. D., Fukahori, H., Goh, Y. S., Lim, W. S., Siah, C. J. R., Seah, B., & Liaw, S. Y. (2024) · Journal of Clinical Nursing · doi:10.1111/jocn.17375 · Cited by 30 · see citing works
Lu, Z., Wang, W., Yan, W., Kew, C. L., Seo, J. H., & Ory, M. G. (2023) · JMIR Serious Games · doi:10.2196/45539 · Cited by 28 · see citing works
Counseling Psychological Understanding and Considerations of the Metaverse: A Theoretical Review
Lee, K. (2023) · Healthcare · doi:10.3390/healthcare11182490 · Cited by 21 · see citing works
Li, Y., Wilke, C., Shiyanov, I., & Muschalla, B. (2024) · JMIR Serious Games · doi:10.2196/50796 · Cited by 20 · see citing works
Li, Y., & Muschalla, B. (2024) · Die Rehabilitation · doi:10.1055/a-2316-6541 · Cited by 22 · see citing works
Xu, L., Fields, N. L., Highfill, C., & Troutman, B. A. (2023) · Behavioral Sciences · doi:10.3390/bs13120998 · Cited by 18 · see citing works
Kruse, C. S., Sen, K., Armenta, V., Hubbard, N., & Brooks, R. (2022) · Healthcare · doi:10.3390/healthcare10101845 · Cited by 16 · see citing works
Pardini, S., Calcagno, R., Genovese, A., Salvadori, E., & Mayora, O. (2025) · Brain Sciences · doi:10.3390/brainsci15050500 · Cited by 13 · see citing works
Matsangidou, M., Solomou, T., Frangoudes, F., Papayianni, E., Kkeli, N., & Pattichi, C. S. (2024) · International Journal of Human-Computer Studies · doi:10.1016/j.ijhcs.2024.103413 · Cited by 13 · see citing works
Ho, K. Y., Cheung, P. M., Cheng, T. W., Suen, W. Y., Ho, H. Y., & Cheung, D. S. K. (2022) · JMIR Aging · doi:10.2196/35224 · Cited by 14 · see citing works
Matsangidou, M., Solomou, T., Frangoudes, F., Papayianni, E., & Pattichis, C. S. (2023) · JMIR Aging · doi:10.2196/45799 · Cited by 12 · see citing works
Flynn, A., Koh, W. Q., Reilly, G., Brennan, A., Redfern, S., Barry, M., & Casey, D. (2024) · International Journal of Human-Computer Interaction · doi:10.1080/10447318.2024.2348838 · Cited by 14 · see citing works
To'mah, V., & du Toit, S. H. J. (2023) · Australian Occupational Therapy Journal · doi:10.1111/1440-1630.12916 · Cited by 11 · see citing works
Interventions to reduce social isolation and food insecurity in older adults: a systematic review
Sen, K., Kruse, C., Mileski, M., & Ramamonjiarivelo, Z. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1607057 · Cited by 8 · see citing works
Holloway, H., Conroy, B., Isbel, S. T., & D'Cunha, N. M. (2024) · Digital Health · doi:10.1177/20552076241249568 · Cited by 9 · see citing works
Effect of Virtual Reality Sessions on the Mental Health of Institutionalized Older Adults
Restout, J., Bernache‐Assollant, I., Mandigout, S., & Perrochon, A. (2025) · Clinical Gerontologist · doi:10.1080/07317115.2025.2462002 · Cited by 9 · see citing works
Buele, J., Avilés-Castillo, F., & Palacios-Navarro, G. (2024) · Current Alzheimer Research · doi:10.2174/0115672050367594250206103806 · Cited by 8 · see citing works
Pereira, M., Leite, C., Campos, C., & Coelho, T. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251371236 · Cited by 8 · see citing works
Time travel of older people through virtual reality: a qualitative study
Muslu, L., Karakuş, Z. N., Asï, E., Bayindir, R., & Özer, Z. (2025) · BMC Geriatrics · doi:10.1186/s12877-025-05699-x · Cited by 6 · see citing works
Clay, F., Hunt, R., Obiefuna, N., Solly, J. E., Watson, E. J., Wilkinson, A., Chohan, R., Hatfield, C. F., Fletcher, P. C., & Underwood, B. R. (2023) · Occupational Therapy In Health Care · doi:10.1080/07380577.2023.2270052 · Cited by 4 · see citing works
Virtual Reality Reminiscence Therapy in Dementia Care: Scoping Review of Research
Matsangidou, M. (2025) · JMIR XR and spatial computing. · doi:10.2196/73539 · Cited by 5 · see citing works
Soares, M., Quental, V. S. A., Pereira, M., Sánchez, A. I. C., Costa, A., Portugal, P., & Coelho, T. (2025) · Dementia · doi:10.1177/14713012251366348 · Cited by 4 · see citing works
Porock, D. C., Cain, P., Young, C., Hilbers, J., Bomm, M., Ghosh, M., & Stanley, M. J. (2024) · Australian Journal on Ageing · doi:10.1111/ajag.13379 · Cited by 4 · see citing works
A Web and Nonimmersive VR Approach for Reminiscence Therapy: A Caregiver Perspective Comparison
Sun, W., Akhter, R., Uribe-Quevedo, Á., Presas, D., Liscano, R., & Horsburgh, S. (2022) · SeGAH ... IEEE ... International Conference on Serious Games and Applications for Health/IEEE International Conference on Serious Games and Applications for Health · doi:10.1109/segah54908.2022.9978303 · Cited by 4 · see citing works
Kwan, R. Y. C., Su, J. J., Lee, J. L. C., Ng, F., Lai, M., Lei, C., & Chan, S. W. (2025) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2025.105307 · Cited by 3 · see citing works
Effectiveness of life story book intervention on apathy and verbal fluency in people with dementia
Asano, T., Wang, C., Tsugaruya, M., & Ishikawa, T. (2022) · Clinical Gerontologist · doi:10.1080/07317115.2022.2147887 · Cited by 3 · see citing works
Suchomelová, V., Diallo, K., & Lhotská, L. (2023) · Caritas et Veritas · doi:10.32725/cetv.2023.007 · Cited by 3 · see citing works
Apathy in dementia: pharmacological and nonpharmacological treatment strategies
Büyükgök, D., İnce, E., & Bılgıç, B. (2025) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000001054 · Cited by 2 · see citing works
Environmental enrichment in cognitive and brain aging
Smith, A. E., Bower, I. S., Fabiani, M., & Karayanidis, F. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-820480-1.00050-4 · Cited by 2 · see citing works
Anderson, K. A., Berg‐Weger, M., Olofinboba, O., & Plocher, T. (2024) · Journal of Applied Gerontology · doi:10.1177/07334648241263234 · Cited by 1 · see citing works
Restout, J., Bernache‐Assollant, I., & Perrochon, A. (2025) · Annales Médico-psychologiques revue psychiatrique · doi:10.1016/j.amp.2025.06.007 · Cited by 1 · see citing works
Restout, J., Perrochon, A., & Bernache‐Assollant, I. (2026) · Geriatric Nursing · doi:10.1016/j.gerinurse.2026.103900 · Cited by 1 · see citing works
Yang, H., Jiao, Y., Zhong, Q., Huang, K., He, R., Jia, Y., & Chen, L. (2026) · Digital Health · doi:10.1177/20552076261426310 · Cited by 1 · see citing works
Reconnecting Seniors with Blue Spaces: A Technology-Mediated Immersive Approach
Pellegrini, T., Pittarello, F., & Pranovi, F. (2026) · International Conference on Advanced Visual Interfaces (AVI) · doi:10.1145/3811427.3811465 · Cited by 1 · see citing works
Mise en place, déroulement et évaluation des INM dans le cadre du projet “Bien vieillir”
Vaillant-Ciszewicz, A.-J., Lantermino, L., Quin, C., Cuni, A., & Guérin, O. (2023) · Soins Gérontologie · doi:10.1016/j.sger.2023.09.006 · Cited by 1 · see citing works
Experiences with the Use of Video Bikes and Virtual Reality in Nursing Homes – a Qualitative Study
Johansen, H., Hermansen, B. E., & Helgesen, A. K. (2024) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s457163 · Cited by 1 · see citing works
Offering Out-World Experiences to Dementia In-patients through Virtual Reality. (Preprint)Preprint
Matsangidou, M., Solomou, T., Frangoudes, F., Papayianni, E., & Pattichis, C. S. (2023) · doi:10.2196/preprints.45799
Stefanyoli, C., Ribeiro, D. J. T., Praça, M., Rocha, P., & Jerónimo, P. (2024) · Seven Editora eBooks · doi:10.56238/sevened2024.012-031
Remote Scoping of an Audio-Reminiscence Tool for Care Home Residents
Bradwell, H. L., Jones, R. B., Cooper, L., Edwards, K. J., Tomaz, S. A., Baxter, R., Baines, R., Page, T., Chatterjee, A., Whittaker, A. C., et al. (2024) · IEEE Symposium on Computers and Communications (ISCC) · doi:10.1109/iscc61673.2024.10733572
Virtual Reality Reminiscence Therapy in Dementia Care: A Systematic Review of Research (Preprint)Preprint
Matsangidou, M. (2025) · doi:10.2196/preprints.73539
APLICAÇÕES DA REALIDADE VIRTUAL NA SAÚDE MENTAL DE IDOSOS: UMA REVISÃO DE ESCOPO
de Amorim, D. R. S. G., Mello, C. P. L. D. A., Borba, M. E. B., Salvador, I. A. T., de Oliveira, L. G. B., Veloso, T. F. D. S., Penante, M. E. F. D. V., de Mello, M. S., & Silva, H. R. D. S. E. (2025) · Brazilian Medical Students · doi:10.53843/bms.v10i14.851
Introducing Virtual Reality to Home-Based Primary Care Veterans With Dementia
Kaneshiro, A. G. (2025) · Journal of the American Psychiatric Nurses Association · doi:10.1177/10783903251335980
Effects of Self-Avatars in Virtual Reality-Based Reminiscence Therapy
Takenaka, S., Mizuho, T., Narumi, T., & Kuzuoka, H. (2025) · Augmented Humans International Conference (AHs) · doi:10.1145/3745900.3746067
Yang, Q., Zhu, D., Muroi, F., Yang, H., Chang, F., & Liu, Z. (2025) · Computers in Human Behavior Reports · doi:10.1016/j.chbr.2025.100875
Caregiver Adoption of Virtual Reality in Dementia Care: A Qualitative Study
Feng, Z., Kurian, J. C., Prasad, M., Biloria, N. M., & Saravanakumar, P. (2026) · Journal of Technology in Behavioral Science · doi:10.1007/s41347-026-00600-y
From Barriers to Blueprints: A Critical Systematic Review of Older Adults and Social VR
Conte, S., Munteanu, C., & Sapkota, A. (2026) · CHI Conference on Human Factors in Computing Systems · doi:10.1145/3772318.3791897
Chou, W.-H., Ko, Y.-L., Tian-yi, Y., Xu, Y.-Y., & YU, W.-W. (2026) · International Journal of Human-Computer Interaction · doi:10.1080/10447318.2026.2664701
Amaro, I., Greca, A. D., Rossi, D., Marco, F. D., Citarella, A. A., Tucci, C., & Biasi, L. D. (2026) · Multimedia Tools and Applications · doi:10.1007/s11042-026-21745-1
Feasibility of Immersive Exergames Using Head-Mounted Displays in Dementia Care: A Pilot Study
Fernandes, P. B., Branco, D., Badia, S. B. I., & Faria, A. L. (2026) · Lecture notes in networks and systems · doi:10.1007/978-3-032-32029-2_14
Preliminary Effects of a Seated Dance and Reminiscence Intervention on Veterans with Dementia
Bates, C. M., Barenie, M. J., Hampton, M., McCulloch, H., & Llewellyn, C. (2026) · Journal of Gerontology and Geriatrics · doi:10.3390/jgg74030021
Heward, M., Szymanska, A., Farrington, S., Fenge, L., Murphy, J., Brittain, G., Clark, M., McMahon, J., Thomas, S., & Tweedy, V. (2026) · Dementia · doi:10.1177/14713012261492094
Chen, D., Wang, H., 苏翠红, Lv, S., He, M., & Li, N. (2026) · Psychogeriatrics · doi:10.1111/psyg.70196
- Authors
- Saredakis, D., Keage, H. A., Corlis, M., Ghezzi, E. S., Loffler, H., & Loetscher, T.
- Affiliations
- University of South Australia (AU)
- Corresponding author
- Saredakis, Dimitrios
- ORCID
- Venue
- Journal of Medical Internet Research
- Publisher
- JMIR Publications Inc.
- Published
- 2021-09-20
- Volume
- 23
- Issue
- 9
- Pages
- e29210
- ISSN
- 1438-8871 (ISSN-L)
- PMC
- PMC8491119
- OpenAlex
- W3184629229
- Cited by
- 61
- References
- 97
- Citations by year
- 2026: 11 · 2025: 15 · 2024: 14 · 2023: 15 · 2022: 6
- FWCI
- 6.28
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Journal of Medical Internet Research (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- UniSA Research Outputs Repository (University of South Australia) (acceptedVersion, other-oa)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Australian Government
- Medical Research Council
- National Health and Medical Research Council (1135676, 1136269)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
- Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
- Keywords
- apathy, reminiscence therapy, virtual reality, head-mounted displays, nursing homes, older adults, non-pharmacological treatment, simulator sickness, depression, cognition, client-centered therapy, information and communication technologies, Simulator Sickness Questionnaire
- MeSH terms
- Virtual Reality, Aged, Australia, Cognition, Humans, Parkinson Disease, Apathy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review