The Potential and Concerns of Using AI in Scientific Research: ChatGPT Performance Evaluation
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Abstract
Background: Artificial intelligence (AI) has many applications in various aspects of our daily life, including health, criminal, education, civil, business, and liability law. One aspect of AI that has gained significant attention is natural language processing (NLP), which refers to the ability of computers to understand and generate human language. Objective: This study aims to examine the potential for, and concerns of, using AI in scientific research. For this purpose, high-impact research articles were generated by analyzing the quality of reports generated by ChatGPT and assessing the application’s impact on the research framework, data analysis, and the literature review. The study also explored concerns around ownership and the integrity of research when using AI-generated text. Methods: A total of 4 articles were generated using ChatGPT, and thereafter evaluated by 23 reviewers. The researchers developed an evaluation form to assess the quality of the articles generated. Additionally, 50 abstracts were generated using ChatGPT and their quality was evaluated. The data were subjected to ANOVA and thematic analysis to analyze the qualitative data provided by the reviewers. Results: When using detailed prompts and providing the context of the study, ChatGPT would generate high-quality research that could be published in high-impact journals. However, ChatGPT had a minor impact on developing the research framework and data analysis. The primary area needing improvement was the development of the literature review. Moreover, reviewers expressed concerns around ownership and the integrity of the research when using AI-generated text. Nonetheless, ChatGPT has a strong potential to increase human productivity in research and can be used in academic writing. Conclusions: AI-generated text has the potential to improve the quality of high-impact research articles. The findings of this study suggest that decision makers and researchers should focus more on the methodology part of the research, which includes research design, developing research tools, and analyzing data in depth, to draw strong theoretical and practical implications, thereby establishing a revolution in scientific research in the era of AI. The practical implications of this study can be used in different fields such as medical education to deliver materials to develop the basic competencies for both medicine students and faculty members.
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When ChatGPT and other AI chatbots were challenged to authenticate their outputs with references, they generated multiple citations with detailed bibliographic data that seemed authentic, but most were fabricated, contained at least one falsified citation datum, or were completely erroneous when verified through medical literature resources.
“Even when ChatGPT and other AI chatbots were challenged to authenticate their outputs with references [13,14], they generated multiple citations with detailed bibliographic data that seemed perfectly authentic, but most were actually fabricated, contained at least one falsified citation data, or were completely erroneous when verified through medical literature resources [13-16].”
From Reference Hallucination Score for Medical Artificial Intelligence Chatbots: Development and Usability Study (2024) · cites this paper as [15]
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Cites
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“Many studies, preprints, blogs, and YouTube (YouTube, LLC/Google LLC) videos have reported multiple benefits of using ChatGPT in higher education, academic writing, technical writing, and medical reports [10].”
BackgroundChatGPT: Applications, Opportunities, and Threats
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“It was stated above that ChatGPT is an AI language model developed and owned by OpenAI, which can be used in higher education, academic writing, and research [10,18].”
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“In short, when using ChatGPT, researchers must be mindful of the legal and regulatory requirements related to their use of the service, including those relating to intellectual property rights, data protection, and privacy [42].”
Why and how to embrace AI such as ChatGPT in your academic life
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“…language models, have become widely adopted for idea generation, drafting, outlining, and providing feedback on academic texts (Barrett and Pack, 2023; Cheng et al., 2025; Dergaa et al., 2023; Escalante et al., 2023; Khlaif et al., 2023; Kim et al., 2024; Nguyen et al., 2024; Song and Song, 2023).”
- Authors
- Khlaif, Z. N., Mousa, A., Hattab, M. K., Itmazi, J., Hassan, A. A., Sanmugam, M., & Ayyoub, A.
- Affiliations
- An-Najah National University (PS)
- Palestine Ahliya University (PS)
- Universiti Sains Malaysia (MY)
- Corresponding author
- Khlaif, Zuheir N
- ORCID
- Venue
- JMIR Medical Education
- Publisher
- JMIR Publications Inc.
- Published
- 2023-09-14
- Volume
- 9
- Pages
- e47049
- ISSN
- 2369-3762 (ISSN-L)
- PMC
- PMC10636627
- OpenAlex
- W4385080756
- Cited by
- 205
- References
- 11
- Citations by year
- 2026: 49 · 2025: 95 · 2024: 60 · 2023: 1
- FWCI
- 8.07
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- JMIR Medical Education (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Greater South Information System
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Physical Sciences › Computer Science › Information Systems › Artificial Intelligence in Education
- Social Sciences › Safety Research › Academic integrity and plagiarism
- Keywords
- ChatGPT, AI-generated text, scientific research, natural language processing, research integrity, research framework development, data analysis, academic writing, prompt quality, peer review concerns
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