Cited by 1Artificial Intelligence in Healthcare and EducationMultimodal Machine Learning ApplicationsTopic Modeling

Model and Task-Aware Test-Time Scaling Strategies for Large Language and Vision-Language Models in Medicine: Evaluation Study

Open access
Oh, Gyutaek, Kim, Seoyeon, Park, Sangjoon, Kim, Byung-Hoon·2026·Journal of Medical Internet Research

Abstract

Background: Test-time scaling has emerged as a promising method to enhance the reasoning capabilities of large language models (LLMs) and vision-language models (VLMs) during inference without additional training. While foundational studies established scaling paradigms in general domains, their applicability to the unique complexities of medical AI remains underexplored. Objective: This study aims to conduct a comprehensive investigation of test-time scaling in the medical domain. We evaluate the impact of scaling across different model sizes and task complexities. Furthermore, we seek to identify domain-specific bottlenecks and assess model robustness against user-driven perturbations, such as misleading clinical authority. Methods: This study evaluated a diverse set of general and medical-specific LLMs and VLMs. Experiments used five textual medical benchmarks comprising over 5500 questions and two multimodal benchmarks comprising 7000 samples. Performance was measured under three scaling conditions: increasing token budgets, iterative sequential scaling, and parallel scaling. Robustness was tested by embedding misleading hints with varying tones and levels of simulated clinical expertise into prompts. Results: For nonreasoning LLMs, accuracy saturated quickly, with token usage often remaining under 500 tokens regardless of budget increases. Reasoning models demonstrated significant performance gains on complex tasks as token budgets increased. Notably, we identified distinct domain-specific behaviors. First, current VLMs showed a structural bottleneck in integrating visual clues and experienced limited benefit from token expansion. Second, medically fine-tuned LLMs excelled in clinical question answering but exhibited degraded scaling efficiency on calculation tasks compared to general-domain models. This reflects a disparity between qualitative clinical alignment and procedural logic. Third, while optimal scaling improved robustness, models exhibited a cognitive vulnerability by readily abandoning correct reasoning when confronted with misleading expert physician hints. Regarding scaling strategies, parallel scaling outperformed sequential scaling on easier tasks. Conversely, extended sequential scaling or increased budgets proved essential for complex problem-solving. Conclusions: Test-time scaling rules from general domains do not perfectly translate to medical AI. Longer reasoning is not universally beneficial. Concise reasoning with parallel scaling is optimal for simpler tasks. An extended chain of thought via sequential scaling or increased budgets is required for complex problems. Furthermore, safe clinical deployment requires addressing fundamental vision-language alignment, balancing clinical and procedural reasoning, and mitigating vulnerabilities to perceived clinical authority.

AI snapshot

Written from the paper’s full text.

TL;DR

This evaluation study tests test-time scaling for medical LLMs and VLMs across token-budget, sequential, parallel, and hybrid strategies, finding that benefits are conditional on model reasoning capacity and task difficulty. It identifies domain-specific bottlenecks in VLM visual integration, medical fine-tuning versus calculation, and vulnerability to misleading expert physician hints.

Key findings

  • Nonreasoning LLMs saturated quickly, often using under 500 tokens regardless of budget increases, while reasoning models improved on complex tasks as token budgets increased; gpt-oss and m1 showed adaptive token use, and m1-32B outperformed larger models on MedXpertQA as the budget increased.
  • VLMs showed limited test-time scaling: most did not increase token use, with exceptions including Qwen3-VL variants, MedGemma-27B, and QVQ; gains were smaller than for LLMs and appeared mainly on difficult MedXpertQA, not easy OmniMedVQA.
  • Medically fine-tuned LLMs excelled on clinical QA but had lower accuracy on MedCalc-Bench than general-domain models, suggesting a disparity between qualitative clinical alignment and procedural calculation reasoning.
  • Parallel scaling outperformed sequential scaling on easier tasks such as PubMedQA, where sequential steps sometimes reduced accuracy; extended sequential scaling or larger token budgets were more effective for complex tasks such as MedXpertQA and MedCalc-Bench. Optimal scaling improved robustness, but misleading expert physician hints still led models to abandon correct reasoning, especially on difficult tasks.

Methods

  • Evaluated general and medical-specific LLMs and VLMs on five textual medical benchmarks comprising over 5500 questions (PubMedQA 500, MedQA 1273, MedBullets 308, MedXpertQA text 2450, MedCalc-Bench 1047) and two multimodal benchmarks comprising 7000 samples (OmniMedVQA 5000, MedXpertQA multimodal 2000).
  • Tested three scaling conditions: increasing token budgets, iterative sequential scaling with a 512-token initial budget and “wait” revisions, and parallel scaling with shortest majority vote; also tested hybrid sequential-parallel scaling. Accuracy and coverage were measured, with temperature 0 for budget/sequential and 0.7 for parallel.
  • Robustness was tested by embedding misleading hints into prompts as another physician’s opinion favoring an incorrect answer, varying tone (hedged vs definitive) and expertise level (novice vs expert) on MedQA, MedBullets, and MedXpertQA.

Limitations

  • The paper states that it did not explore trained verifiers for response selection, that VLM evaluation was less comprehensive than for LLMs, that scaling did not fully restore baseline performance under user-driven perturbations, and that only open-source LLMs were tested, excluding proprietary models such as GPT, Claude, and Gemini.
  • The paper also states that benchmark datasets are finite samples with inherent statistical uncertainty, and that data contamination cannot be completely ruled out, though it argues the focus on relative scaling gains mitigates this concern.
  • Evident from the text: the sequential/parallel scaling and robustness experiments evaluated only two medical reasoning LLMs (HuatuoGPT-o1-7B and m1-7B-1k), which limits generalizability across the broader model set.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.2196/90693

Cites

53 of 53 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

15 of 25 cited sources checked · 9 supported · 0 flagged · accuracy not yet measured

  • Premisecitation

    Test-time scaling has emerged as an effective method for enhancing LLM performance during inference without additional training.

    “To address these challenges, test-time scaling has recently emerged as an effective method for enhancing LLM performance during inference [17-20].”
    Quote in the paperSubstantial claim2 of 4 sources checked
    • cites [17] Muennighoff N Yang Z Shi W et al. S1: simple test-time scaling. In: Hajishirzi H , editor. Presented at: Proceedings of the 2025 Conference on Empirical Methods in Natural Language Processing; Nov 4-9, 2025; Suzhou, China. [doi: 10.18653/v1/2025.emnlp-main.1025] source
    • cites [18] Snell CV Lee J Xu K Kumar A . Scaling LLM test-time compute optimally can be more effective than scaling parameters for reasoning. Presented at: The Thirteenth International Conference on Learning Representations; Apr 24-28, 2025; Singapore EXPO. [doi: 10.18653/v1/2025.emnlp-main] source
    • cites [19] Yang W Ma S Lin Y editors. Towards thinking-optimal scaling of test-time compute for LLM reasoning. In: Wei F , editor. Presented at: The Thirty-ninth Annual Conference on Neural Information Processing Systems; Dec 2-7, 2025; San Diego CA. URL: https://proceedings.neurips.cc/paper_files/paper/2025/hash/3e22bea3b170f4c2aebb9c48d98ae64d-Abstract-Conference.html [Accessed 01-07-2026]

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites [20] Zeng Z Cheng Q Yin Z Zhou Y Qiu X . Revisiting the test-time scaling of o1-like models: do they truly possess test-time scaling capabilities? In: Qiu X , editor. Presented at: Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1); Jul 27 to Aug 1, 2025; Vienna, Austria. [doi: 10.18653/v1/2025.acl-long.232] source
  • Findingnone given

    Medical LLMs generally outperform general domain LLMs on medical QA tasks, except for the recently released Qwen3 variants and gpt-oss.

    “Regarding general vs medical models, as expected, medical LLMs generally outperform general domain LLMs on medical QA tasks, except for the recently released Qwen3 variants and gpt-oss.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • Findingown data

    gpt-oss models achieve higher accuracy on challenging tasks as the token budget expands.

    “The gpt-oss models achieve higher accuracy on challenging tasks as the token budget expands.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • Findingown data

    Nonreasoning LLMs' accuracy quickly saturates and does not improve with increased token budgets.

    “Consequently, as shown in Figure 4, their accuracy quickly saturates and does not improve with increased token budgets.”
    • Also stated in: § Principal Results · plain
      “resulting in negligible accuracy gains.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • Findingown data

    Test-time scaling through increased token budgets can improve performance for certain reasoning LLMs.

    “In summary, test-time scaling through increased token budgets can improve performance for certain reasoning LLMs.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • May combine two claims. 33
  • Classified as probably not a substantial claim. 17
  • The quote only partly states this claim. 1
  • May combine two claims.

    Premisecitation

    Reasoning traces used to train HuatuoGPT-o1 were generated by GPT-4o, while those used for m1 were synthesized by DeepSeek-R1.

    “While the reasoning traces used to train HuatuoGPT-o1 were generated by GPT-4o [6,29], those used for m1 were synthesized by DeepSeek-R1 [9,34].”
    Quote in the paperSubstantial claim4 of 4 sources checked
    • cites [6] Hurst A Lerer A Goucher AP OpenAIet al. GPT-4o system card. arXiv. Preprint posted online on Oct 25, 2024. [doi: 10.48550/arXiv.2410.21276]
    • cites [29] Chen J Cai Z Ji K et al. Towards medical complex reasoning with llms through medical verifiable problems. Presented at: Findings of the Association for Computational Linguistics: ACL 2025; Jul 27 to Aug 1, 2025; Vienna, Austria. [doi: 10.18653/v1/2025.findings-acl.751] source
    • cites [9] Guo, DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning, Nature source
    • cites [34] Huang X Wu J Liu H Tang X Zhou Y . M1: unleash the potential of test-time scaling for medical reasoning with large language models. the second workshop on genai for health: potential, trust, and policy compliance. arXiv. Preprint posted online on Apr 1, 2025. [doi: 10.48550/arXiv.2504.00869] source
  • May combine two claims.

    Interpretationreasoning

    General-domain test-time scaling findings cannot readily predict the multilayered complexities inherent to clinical AI and fail to capture domain-specific bottlenecks and behavioral shifts in medical environments.

    “Crucially, while foundational studies have established test-time scaling paradigms in the general domain by focusing primarily on text-based logic such as mathematics and coding [18-20], their findings cannot readily predict the multilayered complexities inherent to clinical AI.”
    • Also stated in: § Background · plain
      “General-domain frameworks fail to capture the domain-specific bottlenecks and unique behavioral shifts that emerge in medical environments.”
    Quote in the paperSubstantial claim1 of 3 sources checked
    • cites [18] Snell CV Lee J Xu K Kumar A . Scaling LLM test-time compute optimally can be more effective than scaling parameters for reasoning. Presented at: The Thirteenth International Conference on Learning Representations; Apr 24-28, 2025; Singapore EXPO. [doi: 10.18653/v1/2025.emnlp-main] source
    • cites [19] Yang W Ma S Lin Y editors. Towards thinking-optimal scaling of test-time compute for LLM reasoning. In: Wei F , editor. Presented at: The Thirty-ninth Annual Conference on Neural Information Processing Systems; Dec 2-7, 2025; San Diego CA. URL: https://proceedings.neurips.cc/paper_files/paper/2025/hash/3e22bea3b170f4c2aebb9c48d98ae64d-Abstract-Conference.html [Accessed 01-07-2026]

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites [20] Zeng Z Cheng Q Yin Z Zhou Y Qiu X . Revisiting the test-time scaling of o1-like models: do they truly possess test-time scaling capabilities? In: Qiu X , editor. Presented at: Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1); Jul 27 to Aug 1, 2025; Vienna, Austria. [doi: 10.18653/v1/2025.acl-long.232] source

      The Benchmark section (page not provided) evaluates test-time scaling on three mathematical-reasoning benchmarks and GPQA, a broader science benchmark, supporting the general-domain context. The paper does not assess clinical AI or establish that its findings fail to predict clinical complexities, domain-specific bottlenecks, or behavioral shifts in medical settings. (LLM, conf=0.82)

      Experimental — accuracy not yet measured
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The combination of reasoning models and test-time scaling has shown state-of-the-art results on complex tasks such as mathematics problem solving and program code synthesis.

    “The combination of reasoning models and test-time scaling has shown state-of-the-art results on complex tasks such as mathematics problem solving and program code synthesis [6,9].”
    Quote in the paperNot a substantial claim2 of 2 sources checked
    • cites [6] Hurst A Lerer A Goucher AP OpenAIet al. GPT-4o system card. arXiv. Preprint posted online on Oct 25, 2024. [doi: 10.48550/arXiv.2410.21276]

      Section 2 (p. 1) says code and math training data help GPT-4o develop reasoning skills, but does not report state-of-the-art results. Searches for test-time scaling, mathematics problem solving, and code synthesis found no passage establishing the claimed combination or its performance; our copy may omit the end of the paper. (LLM, conf=0.68)

      Experimental — accuracy not yet measured
    • cites [9] Guo, DeepSeek-R1 incentivizes reasoning in LLMs through reinforcement learning, Nature source
  • May combine two claims.

    Premisecitation

    Test-time scaling improves both reliability and accuracy, especially on tasks that require multistep reasoning, without additional training or fine-tuning.

    “Without requiring additional training or fine-tuning, test-time scaling improves both reliability and accuracy, especially on tasks that require multistep reasoning.”
    Quote in the paperSubstantial claim2 of 4 sources checked
    • cites [17] Muennighoff N Yang Z Shi W et al. S1: simple test-time scaling. In: Hajishirzi H , editor. Presented at: Proceedings of the 2025 Conference on Empirical Methods in Natural Language Processing; Nov 4-9, 2025; Suzhou, China. [doi: 10.18653/v1/2025.emnlp-main.1025] source

      The Introduction and §4.2 Performance report that increasing test-time compute improves s1-32B’s results on reasoning benchmarks, including AIME24. Budget forcing is a test-time intervention, but the paper says s1-32B was first fine-tuned on 1,000 examples; it does not establish improved reliability as a separate outcome. Thus the claim is supported for accuracy on reasoning tasks, but not as an unqualified improvement without fine-tuning. (LLM, conf=0.87)

      Experimental — accuracy not yet measured
    • cites [18] Snell CV Lee J Xu K Kumar A . Scaling LLM test-time compute optimally can be more effective than scaling parameters for reasoning. Presented at: The Thirteenth International Conference on Learning Representations; Apr 24-28, 2025; Singapore EXPO. [doi: 10.18653/v1/2025.emnlp-main] source
    • cites [19] Yang W Ma S Lin Y editors. Towards thinking-optimal scaling of test-time compute for LLM reasoning. In: Wei F , editor. Presented at: The Thirty-ninth Annual Conference on Neural Information Processing Systems; Dec 2-7, 2025; San Diego CA. URL: https://proceedings.neurips.cc/paper_files/paper/2025/hash/3e22bea3b170f4c2aebb9c48d98ae64d-Abstract-Conference.html [Accessed 01-07-2026]

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites [20] Zeng Z Cheng Q Yin Z Zhou Y Qiu X . Revisiting the test-time scaling of o1-like models: do they truly possess test-time scaling capabilities? In: Qiu X , editor. Presented at: Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1); Jul 27 to Aug 1, 2025; Vienna, Austria. [doi: 10.18653/v1/2025.acl-long.232] source

      The Introduction and Section 5 (page numbers unavailable) report that parallel test-time scaling improves performance and coverage on reasoning benchmarks. But the paper does not establish an improvement in reliability, and it finds that longer reasoning chains and sequential self-revision do not consistently improve accuracy. The claim overgeneralizes the benefit to test-time scaling as a whole. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
  • Classified as probably not a substantial claim.

    Premisecitation

    Recent studies demonstrate that the use of reasoning models and test-time scaling significantly boosts performance on medical benchmark datasets.

    “Recent studies demonstrate that the use of reasoning models and test-time scaling significantly boosts performance on medical benchmark datasets [30].”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites [30] Jiang S Liao Y Chen Z Zhang Y Wang Y Wang Y . MedS: towards medical slow thinking with self-evolved soft dual-sided process supervision. In: Wang Y , editor. Presented at: The Fortieth AAAI Conference on Artificial Intelligence (AAAI-26); Feb 25 to Mar 4, 2025:31319-31327; Philadelphia,PA. [doi: 10.1609/aaai.v40i37.40395] source
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Prior studies on test-time scaling in general domains have established that increasing inference compute can improve reasoning, though the relationship is not strictly monotonic.

    “Prior studies on test-time scaling in general domains, such as mathematics and coding, have established that increasing inference compute can improve reasoning, though the relationship is not strictly monotonic.”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites [18] Snell CV Lee J Xu K Kumar A . Scaling LLM test-time compute optimally can be more effective than scaling parameters for reasoning. Presented at: The Thirteenth International Conference on Learning Representations; Apr 24-28, 2025; Singapore EXPO. [doi: 10.18653/v1/2025.emnlp-main] source
    • cites [19] Yang W Ma S Lin Y editors. Towards thinking-optimal scaling of test-time compute for LLM reasoning. In: Wei F , editor. Presented at: The Thirty-ninth Annual Conference on Neural Information Processing Systems; Dec 2-7, 2025; San Diego CA. URL: https://proceedings.neurips.cc/paper_files/paper/2025/hash/3e22bea3b170f4c2aebb9c48d98ae64d-Abstract-Conference.html [Accessed 01-07-2026]

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites [20] Zeng Z Cheng Q Yin Z Zhou Y Qiu X . Revisiting the test-time scaling of o1-like models: do they truly possess test-time scaling capabilities? In: Qiu X , editor. Presented at: Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1); Jul 27 to Aug 1, 2025; Vienna, Austria. [doi: 10.18653/v1/2025.acl-long.232] source

      The Related Work section says increasing computation during inference can improve performance, and the Self-Revision results show that accuracy can initially improve before oscillating or declining. The Benchmark section covers mathematical and scientific reasoning, but not coding, so the citing sentence’s coding example is not supported by this paper. (LLM, conf=0.84)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Premisecitation

    Qwen3-VL models were posttrained using SFT, distillation, and Soft Adaptive Policy Optimization, an RL method specifically proposed for Qwen3-VL.

    “For instance, the Qwen3-VL models were posttrained using SFT, distillation, and Soft Adaptive Policy Optimization [57], an RL method specifically proposed for Qwen3-VL.”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites [57] Gao C Zheng C Chen XH et al. Soft adaptive policy optimization. arXiv. Preprint posted online on Nov 25, 2025. [doi: 10.48550/arXiv.2511.20347] source

      Section 5.2 (p. 8) says the authors used SAPO to train Qwen3-VL models, and Section 3 (p. 3) identifies SAPO as an RL fine-tuning method. The paper presents SAPO as a method for large language models generally, not one specifically proposed for Qwen3-VL. Our copy also does not establish the sentence’s SFT and distillation claims. (LLM, conf=0.87)

      Experimental — accuracy not yet measured
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    Optimal reasoning lengths exist and excessive self-revision can sometimes degrade performance.

    “These works demonstrate that optimal reasoning lengths exist and that excessive self-revision can sometimes degrade performance [18-20].”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites [18] Snell CV Lee J Xu K Kumar A . Scaling LLM test-time compute optimally can be more effective than scaling parameters for reasoning. Presented at: The Thirteenth International Conference on Learning Representations; Apr 24-28, 2025; Singapore EXPO. [doi: 10.18653/v1/2025.emnlp-main] source
    • cites [19] Yang W Ma S Lin Y editors. Towards thinking-optimal scaling of test-time compute for LLM reasoning. In: Wei F , editor. Presented at: The Thirty-ninth Annual Conference on Neural Information Processing Systems; Dec 2-7, 2025; San Diego CA. URL: https://proceedings.neurips.cc/paper_files/paper/2025/hash/3e22bea3b170f4c2aebb9c48d98ae64d-Abstract-Conference.html [Accessed 01-07-2026]

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites [20] Zeng Z Cheng Q Yin Z Zhou Y Qiu X . Revisiting the test-time scaling of o1-like models: do they truly possess test-time scaling capabilities? In: Qiu X , editor. Presented at: Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1); Jul 27 to Aug 1, 2025; Vienna, Austria. [doi: 10.18653/v1/2025.acl-long.232] source
  • May combine two claims.

    Findingown data

    Medically fine-tuned LLMs excelled in clinical question answering but exhibited degraded scaling efficiency on calculation tasks compared to general-domain models.

    “Second, medically fine-tuned LLMs excelled in clinical question answering but exhibited degraded scaling efficiency on calculation tasks compared to general-domain models.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The medical benchmark datasets used are valid proxies for real-world clinical tasks and reasoning.
  • May combine two claims.

    Findingown data

    While optimal scaling improved robustness, models exhibited a cognitive vulnerability by readily abandoning correct reasoning when confronted with misleading expert physician hints.

    “Third, while optimal scaling improved robustness, models exhibited a cognitive vulnerability by readily abandoning correct reasoning when confronted with misleading expert physician hints.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: Embedding misleading hints with varying tones and simulated clinical expertise adequately simulates user-driven perturbations such as misleading clinical authority.
  • May combine two claims.

    Findingown data

    For nonreasoning LLMs, accuracy saturated quickly, with token usage often remaining under 500 tokens regardless of budget increases.

    “For nonreasoning LLMs, accuracy saturated quickly, with token usage often remaining under 500 tokens regardless of budget increases.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The medical benchmark datasets used are valid proxies for real-world clinical tasks and reasoning.
  • Classified as probably not a substantial claim.

    Findingnone given

    Many existing LLMs that benefit from increased token budgets are not specifically designed for the medical domain.

    “However, many existing LLMs that benefit from this approach are not specifically designed for the medical domain.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    m1 effectively uses a larger portion of the available token budget and exhibits substantial performance improvements as the token budget increases.

    “In contrast, m1 effectively uses a larger portion of the available token budget and exhibits substantial performance improvements as the token budget increases.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • May combine two claims.

    Findingown data

    QVQ displays test-time scaling on both benchmarks, but its performance is lower on the simpler OmniMedVQA and higher on the more challenging MedXpertQA.

    “Interestingly, while QVQ displays test-time scaling on both benchmarks, its performance is paradoxically lower on the simpler OmniMedVQA and higher on the more challenging MedXpertQA.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • May combine two claims.

    Findingown data

    Extended sequential scaling or increased budgets proved essential for complex problem-solving.

    “Conversely, extended sequential scaling or increased budgets proved essential for complex problem-solving.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The medical benchmark datasets used are valid proxies for real-world clinical tasks and reasoning.
  • May combine two claims.

    Findingnone given

    Current VLMs showed a structural bottleneck in integrating visual clues and experienced limited benefit from token expansion.

    “First, current VLMs showed a structural bottleneck in integrating visual clues and experienced limited benefit from token expansion.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The medical benchmark datasets used are valid proxies for real-world clinical tasks and reasoning.
  • May combine two claims.

    Findingnone given

    DeepSeek-R1 or Qwen3-TH models tend to use more tokens for reasoning as the token budget increases, and perform better with increased token budgets.

    “For example, DeepSeek-R1 or Qwen3-TH models tend to use more tokens for reasoning as the token budget increases, and perform better with increased token budgets.”
    Quote in the paperNot a substantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • Classified as probably not a substantial claim. May combine two claims.

    Findingnone given

    General nonreasoning models have limited medical knowledge and relatively low performance on reasoning-intensive medical question answering tasks.

    “Limited medical knowledgeRelatively low performance on reasoning-intensive medical question answering tasks”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Medically fine-tuned LLMs excel in text-based medical QA but exhibit degraded scaling efficiency on clinical calculation tasks compared to general-domain models.

    “we demonstrate that medically fine-tuned LLMs excel in text-based medical QA but exhibit degraded scaling efficiency on clinical calculation tasks compared to general-domain models.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Test-time scaling by increasing the token budget shows effectiveness only for some models, and even then, the performance gains in VLMs are considerably smaller than those observed in LLMs.

    “This approach shows effectiveness only for some models, and even then, the performance gains in VLMs are considerably smaller than those observed in LLMs.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • May combine two claims.

    Findingnone given

    m1 relies on generating long, uninterrupted reasoning chains and performs best with a simple expansion of the token budget.

    “However, m1 relies on generating long, uninterrupted reasoning chains and performs best with a simple expansion of the token budget.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingnone given

    General reasoning models perform well on medical calculation tasks and high performance on reasoning-intensive tasks.

    “Performs well on medical calculation tasksHigh performance on reasoning-intensive tasks”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    For simpler tasks, extensive reasoning is unnecessary, and models that produce concise reasoning traces offer better computational efficiency.

    “For simpler tasks, extensive reasoning is unnecessary, and models that produce concise reasoning traces offer better computational efficiency.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingnone given

    Medical reasoning models perform well on medical question-answering tasks and high performance on reasoning-intensive tasks.

    “Performs well on medical question-answering tasksHigh performance on reasoning-intensive tasks”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    MedGemma-27B demonstrates improved performance on MedXpertQA as the token budget expands, whereas the smaller MedGemma-4B does not.

    “In our experiment, MedGemma-27B demonstrates improved performance on MedXpertQA as the token budget expands, whereas the smaller MedGemma-4B does not.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • May combine two claims.

    Findingown data

    For complex and challenging tasks, generating longer chain-of-thought reasoning leads to better performance, with models capable of producing extended reasoning traces outperforming their counterparts.

    “In contrast, for complex and challenging tasks, generating longer chain-of-thought reasoning leads to better performance, with models capable of producing extended reasoning traces outperforming their counterparts.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Scaling strategies generally mitigated the negative impact of misleading expert hints but often failed to fully restore baseline performance on difficult tasks.

    “We observed that scaling strategies generally mitigated the negative impact of misleading expert hints but often failed to fully restore baseline performance on difficult tasks.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    The effectiveness of test-time scaling in VLMs is more pronounced on more difficult tasks, while it has little to no impact on simpler tasks.

    “Notably, as in the case of LLMs, the effectiveness of test-time scaling in VLMs is more pronounced on more difficult tasks, while it has little to no impact on simpler tasks.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The ground truth labels in the benchmark datasets are correct.
  • May combine two claims.

    Findingreasoning

    Parallel scaling minimizes the increase in GPU memory footprint to just the required key-value cache and significantly reduces wall-clock time.

    “This minimizes the increase in GPU memory footprint to just the required key-value cache and significantly reduces wall-clock time”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationreasoning

    The underlying models differ in reasoning styles and output structures, likely leading to variations in the length and structure of chain-of-thought traces and influencing how each model uses tokens during inference.

    “These underlying models differ in their reasoning styles and output structures, likely leading to variations in the length and structure of chain-of-thought traces and influencing how each model uses tokens during inference.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationreasoning

    QVQ's performance on MedXpertQA benefits from the presence of more informative textual clues within the questions, while the questions of OmniMedVQA are very simple.

    “In contrast, the performance of QVQ on MedXpertQA benefits from the presence of more informative textual clues within the questions, while the questions of OmniMedVQA are very simple”
    Quote in the paperSubstantial claim
  • The quote only partly states this claim.

    Interpretationreasoning

    The disparity between qualitative clinical alignment and procedural logic reflects the difference in scaling efficiency between medically fine-tuned and general-domain models on calculation tasks.

    “This reflects a disparity between qualitative clinical alignment and procedural logic.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: The medical benchmark datasets used are valid proxies for real-world clinical tasks and reasoning.
  • May combine two claims.

    Interpretationreasoning

    These clues often enable QVQ to infer the correct answer even without fully using the image, thus reducing the impact of its visual processing limitations.

    “These clues often enable the model to infer the correct answer even without fully using the image, thus reducing the impact of its visual processing limitations.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationreasoning

    The stronger performance of general-purpose models on MedCalc-Bench does not necessarily imply deficient medical reasoning overall; it indicates that the benchmark captures a narrower procedural capability that is less tied to domain-specific clinical expertise.

    “Therefore, the stronger performance of general-purpose models does not necessarily imply deficient medical reasoning overall. Instead, it indicates that the benchmark captures a narrower procedural capability that is less tied to domain-specific clinical expertise.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    Minimizing perturbations by providing only neutral and essential information for complex tasks is important.

    “emphasizing the importance of minimizing perturbations by providing only neutral and essential information for complex tasks.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S4 (based).

    Premisenone given

    Generating the same number of tokens with a large-scale model consumes substantially more compute, energy, and financial resources than a smaller model.

    “Generating the same number of tokens with a large-scale model consumes substantially more compute (floating point operations per second), energy, and financial resources than a smaller model.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    Understanding when and how to appropriately scale reasoning at test time is a crucial foundational step toward developing clinical AI systems that are computationally efficient, robust, resilient, and trustworthy in high-stakes health care environments.

    “Ultimately, understanding when and how to appropriately scale reasoning at test time is a crucial foundational step toward developing clinical AI systems that are not only computationally efficient but also robust, resilient, and trustworthy in high-stakes health care environments.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).

    Interpretationnone given

    Compared to LLMs, VLMs require more comprehensive evaluation under test-time scaling.

    “In addition, compared to LLMs, VLMs require more comprehensive evaluation under test-time scaling.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationreasoning

    Current medical alignment heavily prioritizes qualitative clinical knowledge over the general numerical and procedural reasoning captured by calculation benchmarks, leading medically fine-tuned models to be less optimized for calculation-heavy tasks rather than having impaired reasoning capabilities.

    “it suggests that current medical alignment heavily prioritizes qualitative clinical knowledge over the general numerical and procedural reasoning captured by calculation benchmarks.”
    • Also stated in: § Conclusions · hedged
      “This trend likely reflects that current medical fine-tuning practices heavily focus on qualitative textual medical knowledge, meaning these models are less optimized for the procedural, calculation-heavy demands captured by such benchmarks rather than enduring an actual impairment of reasoning capabilities.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    Treating inference compute as a static resource is no longer viable or safe.

    “treating inference compute as a static resource is no longer viable or safe.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim.

    Interpretationreasoning

    Current vision-language medical benchmarks may not be well-suited for evaluating reasoning ability.

    “Next, the limitations may stem from the current vision-language medical benchmarks, which may not be well-suited for evaluating reasoning ability.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    Evaluating deployment feasibility requires balancing reasoning performance against strict computational constraints.

    “Therefore, evaluating deployment feasibility requires balancing reasoning performance against strict computational constraints.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim. May combine two claims.

    Interpretationreasoning

    Most contemporary VLMs still struggle with or entirely lack the ability to jointly and effectively reason over complex visual cues in conjunction with textual information, which may explain the relatively limited performance on MedXpertQA compared to LLMs.

    “Most contemporary VLMs still struggle with or entirely lack the ability to jointly and effectively reason over such complex visual cues in conjunction with textual information, which may explain the relatively limited performance on this benchmark compared to that of LLMs.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    Ensuring patient safety, diagnostic accuracy, and operational efficiency requires a dynamic approach to model deployment.

    “Our study highlights that ensuring patient safety, diagnostic accuracy, and operational efficiency requires a dynamic approach to model deployment.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationreasoning

    Sequential scaling inherently increases latency due to its serial nature and expanding context length, limiting its use to nonurgent, complex diagnostic scenarios.

    “Conversely, sequential scaling inherently increases latency due to its serial nature and expanding context length, limiting its use to nonurgent, complex diagnostic scenarios.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S2 (checkable).

    Interpretationreasoning

    Computational strategies must be carefully tailored to the specific urgency and complexity of the medical scenario.

    “Computational strategies must be carefully tailored to the specific urgency and complexity of the medical scenario.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim.

    Premisereasoning

    Token count does not equate to equal computational cost across different model architectures.

    “token count does not equate to equal computational cost across different model architectures.”
    Quote in the paperSubstantial claim
47 of 47
  • The paper relies on this without support.

    The medical benchmark datasets used are valid proxies for real-world clinical tasks and reasoning.

    “In our experiments, we evaluate LLMs on five medical benchmark datasets, including four medical question answering (QA) datasets and one medical calculation dataset.”
  • The paper relies on this without support.

    Embedding misleading hints with varying tones and simulated clinical expertise adequately simulates user-driven perturbations such as misleading clinical authority.

    “Robustness was tested by embedding misleading hints with varying tones and levels of simulated clinical expertise into prompts.”
  • The paper relies on this without support.

    The ground truth labels in the benchmark datasets are correct.

    “we extract the conclusion from the generated output and strictly compare it against the ground truth label of the dataset.”
  • The paper relies on this without support.

    The benchmark datasets (MedQA, Medbullets, MedXpertQA, PubMedQA, OmniMedVQA, MedCalc-Bench) adequately represent medical reasoning tasks.

    “We also investigate whether test-time scaling enhances the robustness of LLMs to user-driven factors using three medical QA benchmark datasets: MedQA, Medbullets, and MedXpertQA.”
  • The paper relies on this without support.

    The evaluated LLMs and VLMs are representative of current medical and general-domain models.

    “we evaluate two medical reasoning LLMs: HuatuoGPT-o1-7B (denoted as HuatuoGPT-7B) and m1-7B-1k (denoted as m1-7B).”
  • The authors state this as an assumption.

    Public benchmark questions might have been included in the base models' pretraining corpora (data contamination).

    “we cannot completely rule out the possibility of data contamination, where public benchmark questions might have been included in the base models’ pretraining corpora.”
  • The paper relies on this without support.

    The benchmark datasets used for evaluation are finite samples of the broader population of real-world medical questions.

    “the evaluation relies on specific benchmark datasets, which serve as finite samples of the much broader population of real-world medical questions.”
  • The paper relies on this without support.

    Token count is a valid proxy for reasoning length or cognitive limits.

    “our experimental design controls for the token budget to evaluate the cognitive limits of reasoning length”
  • The paper relies on this without support.

    Benchmark performance generalizes to real-world clinical deployment.

    “these findings hold broader implications for the real-world deployment of medical AI”
9 of 9

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

  • Qwen3-Instruct small-model size differs between text and Table 2

    Minor

    The Models section says the smaller Qwen3-Instruct model is 8B, while Table 2 lists it as 4B.

  • Qwen3-Thinking small-model size differs between text and Table 2

    Minor

    The Models section says the smaller Qwen3-Thinking model is 8B, while Table 2 lists it as 4B.

2 of 2

Cites

Flagged first, then by citations

Research works printed but not linked: 8

  1. Brown T Mann B Ryder N et al. Language models are few-shot learners. Presented at: NIPS’20: Proceedings of the 34th International Conference on Neural Information Processing Systems; Dec 6-12, 2020:1877-1901; Vancouver, British Columbia, Canada. URL: https://proceedings.neurips.cc/paper/2020/file/1457c0d6bfcb4967418bfb8ac142f64a-Paper.pdf [Accessed 01-07-2026]
  2. Li J Li D Xiong C . BLIP: bootstrapping language-image pre-training for unified vision-language understanding and generation. In: Hoi S , editor. Presented at: International Conference on Machine Learning; Jul 17-23, 2022; Baltimore MD. URL: https://proceedings.mlr.press/v162/li22n/li22n.pdf [Accessed 01-07-2026]
  3. Li J Li D Savarese S editors. BLIP-2: bootstrapping language-image pre-training with frozen image encoders and large language models. In: Hoi S , editor. Presented at: International Conference on Machine Learning; Jul 23-29, 2023; Honolulu HI. URL: https://proceedings.mlr.press/v202/li23q/li23q.pdf [Accessed 01-07-2026]
  4. Yang W Ma S Lin Y editors. Towards thinking-optimal scaling of test-time compute for LLM reasoning. In: Wei F , editor. Presented at: The Thirty-ninth Annual Conference on Neural Information Processing Systems; Dec 2-7, 2025; San Diego CA. URL: https://proceedings.neurips.cc/paper_files/paper/2025/hash/3e22bea3b170f4c2aebb9c48d98ae64d-Abstract-Conference.html [Accessed 01-07-2026]
  5. Dai W Chen P Ekbote C Liang PP . QoQ-med: building multimodal clinical foundation models with domain-aware GRPO training. Presented at: 39th Conference on Neural Information Processing Systems (NeurIPS 2025); Dec 2-7, 2025; San Diego, CA. URL: https://proceedings.neurips.cc/paper_files/paper/2025/file/359ffa88712bd688963a0ca641d8330b-Paper-Conference.pdf [Accessed 02-07-2026]
  6. Kaya MO Elliott D Papadopoulos DP . Efficient test-time scaling for small vision-language models. Presented at: The Fourteenth International Conference on Learning Representations; Apr 23-27, 2026; Rio de Janeiro, Brazil. URL: https://monurcan.github.io/efficient_test_time_scaling/ [Accessed 04-07-2026]
  7. Zuo Y Qu S Li Y . MedXpertQA: benchmarking expert-level medical reasoning and understanding. In: Hua E , editor. Presented at: Proceedings of the 42nd International Conference on Machine Learning; Jul 13-19, 2025; Vancouver, British Columbia, Canada. URL: https://openreview.net/pdf?id=IyVcxU0RKI [Accessed 02-07-2026]
  8. Dai W Chen P Lu M et al. CLIMB: data foundations for large scale multimodal clinical foundation models. In: Cui H , editor. Presented at: Forty-second International Conference on Machine Learning; Jul 13-19, 2025; Vancouver, British Columbia, Canada. URL: https://openreview.net/pdf?id=TcvjOSePic [Accessed 02-07-2026]

Cited by

Sorted by citations

Authors
Oh, G., Kim, S., Park, S., & Kim, B.-H.
Affiliations
Yonsei University (KR)
Venue
Journal of Medical Internet Research
Published
2026-07-23
Volume
28
Pages
e90693-e90693
ISSN
1438-8871 (ISSN-L)
OpenAlex
W7170198514
Cited by
1
References
26
Citations by year
2026: 1
FWCI
2.02
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Journal of Medical Internet Research (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • PubMed Central (submittedVersion, cc-by)
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Multimodal Machine Learning Applications
  • Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
Keywords
test-time scaling, large language models, vision-language models, artificial intelligence in healthcare, token budget, parallel scaling, chain-of-thought reasoning, medical question answering
MeSH terms
Large Language Models, Humans, Medical Informatics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-07.

Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-07.

Cited sources are checked by gpt-6-sol.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

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