The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
Characterization of Nanoparticles for Therapeutics
Abstract
Nanotechnology offers many advantages to traditional drug design, delivery and medical diagnostics; however, nanomedicines present considerable challenges for preclinical development. Nanoparticle constructs intended for medical applications consist of a wide variety of materials, and their small size, unique physicochemical properties and biological activity often require modification of standard characterization techniques. A rational characterization strategy for nanomedicines includes physicochemical characterization, sterility and pyrogenicity assessment, biodistribution (absorption, distribution, metabolism and excretion [ADME]) and toxicity characterization, which includes both in vitro tests and in vivo animal studies. Here, we highlight progress for a few methods that are uniquely useful for nanoparticles or are indicative of their toxicity or efficacy.
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Cites
1 retracted
RETRACTED: Polyethylenimine nanoparticles as efficient transfecting agents for mammalian cells
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Self-citation
Cited by
Batrakova, E. V., & Kabanov, A. V. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.04.013 · Cited by 1,278
Dobrovolskaia, M. A., Aggarwal, P., Hall, J. B., & McNeil, S. E. (2008) · Molecular Pharmaceutics · doi:10.1021/mp800032f · Cited by 1,022
Self-citationXu, W., Ling, P., & Zhang, T. (2013) · Journal of Drug Delivery · doi:10.1155/2013/340315 · Cited by 595
Inhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?
Callaghan, R., Luk, F., & Bebawy, M. (2014) · Drug Metabolism and Disposition · doi:10.1124/dmd.113.056176 · Cited by 453
Kus-Liśkiewicz, M., Fickers, P., & Ben Tahar, I. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222010952 · Cited by 404
Metadata
- Authors
- Hall, J. B., Dobrovolskaia, M. A., Patri, A. K., & McNeil, S. E.
- Venue
- Nanomedicine
- Publisher
- Informa UK Limited
- Published
- 2007-12
- Volume
- 2
- Issue
- 6
- Pages
- 789-803
- ISSN
- 1743-5889 (ISSN-L)
- 1748-6963
- OpenAlex
- W2135913252
- Cited by
- 409
- References
- 61
- FWCI
- 5.62
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hall, J. B., Dobrovolskaia, M. A., Patri, A. K., & McNeil, S. E. (2007). Characterization of Nanoparticles for Therapeutics. Nanomedicine. https://doi.org/10.2217/17435889.2.6.789
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
