The DOI matches its Crossref record; 307 of the 307 references it cites were found in a registry or an index.
Epigenetics and Allergy: from Basic Mechanisms to Clinical Applications
Open accessAbstract
Allergic diseases are on the rise in the Western world and well-known allergy-protecting and -driving factors such as microbial and dietary exposure, pollution and smoking mediate their influence through alterations of the epigenetic landscape. Here, we review key facts on the involvement of epigenetic modifications in allergic diseases and summarize and critically evaluate the lessons learned from epigenome-wide association studies. We show the potential of epigenetic changes for various clinical applications: as diagnostic tools, to assess tolerance following immunotherapy or possibly predict the success of therapy at an early time point. Furthermore, new technological advances such as epigenome editing and DNAzymes will allow targeted alterations of the epigenome in the future and provide novel therapeutic tools.
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Citations
Cites
2 retracted
In utero supplementation with methyl donors enhances allergic airway disease in mice
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RetractedIn utero supplementation with methyl donors enhances allergic airway disease in mice
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Cited by
Atopic dermatitis endotypes and implications for targeted therapeutics
Czarnowicki, T., He, H., Krueger, J. G., & Guttman-Yassky, E. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.10.032 · Cited by 631
Advances and novel developments in mechanisms of allergic inflammation
Han, X., Krempski, J. W., & Nadeau, K. (2020) · Allergy · doi:10.1111/all.14632 · Cited by 129
Genetics and epigenetics of atopic dermatitis: an updated systematic review
Martin, M. J., Estravís, M., García-Sánchez, A., Dávila, I., Isidoro-García, M., & Sanz, C. (2020) · Genes · doi:10.3390/genes11040442 · Cited by 99
Network Medicine in Pathobiology
Lee, L. Y.-H., & Loscalzo, J. (2019) · The American Journal of Pathology · doi:10.1016/j.ajpath.2019.03.009 · Cited by 95
Understanding asthma and allergies by the lens of biodiversity and epigenetic changes
Fiuza, B. S. D., Fonseca, H. F., Meirelles, P. M., Marques, C. R., da Silva, T. M., & Figueiredo, C. A. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.623737 · Cited by 38
Metadata
- Authors
- Potaczek, D. P., Harb, H., Michel, S., Alhamwe, B. A., Renz, H., & Tost, J.
- Venue
- Epigenomics
- Publisher
- Informa UK Limited
- Published
- 2017-03-21
- Volume
- 9
- Issue
- 4
- Pages
- 539-571
- ISSN
- 1750-1911 (ISSN-L)
- 1750-192X
- OpenAlex
- W2601211966
- Cited by
- 284
- References
- 307
- FWCI
- 10.09
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Potaczek, D. P., Harb, H., Michel, S., Alhamwe, B. A., Renz, H., & Tost, J. (2017). Epigenetics and Allergy: from Basic Mechanisms to Clinical Applications. Epigenomics. https://doi.org/10.2217/epi-2016-0162
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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