BCOR Involvement in Cancer

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

Louis, D. N., Perry, A., Reifenberger, G., von Deimling, A., Figarella‐Branger, D., Cavenee, W. K., Ohgaki, H., Wiestler, O. D., Kleihues, P., & Ellison, D. W. (2016) · Acta Neuropathologica · doi:10.1007/s00401-016-1545-1 · Cited by 15,703 · see citing works

The 2007 WHO Classification of Tumours of the Central Nervous System

Louis, D. N., Ohgaki, H., Wiestler, O. D., Cavenee, W. K., Burger, P. C., Jouvet, A., Scheithauer, B. W., & Kleihues, P. (2007) · Acta Neuropathologica · doi:10.1007/s00401-007-0243-4 · Cited by 15,422 · see citing works

Frequent pathway mutations of splicing machinery in myelodysplasia

Yoshida, K., Sanada, M., Shiraishi, Y., Nowak, D., Nagata, Y., Yamamoto, R., Sato, Y., Sato-Otsubo, A., Kon, A., Nagasaki, M., et al. (2011) · Nature · doi:10.1038/nature10496 · Cited by 2,029 · see citing works

Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

Haferlach, T., Nagata, Y., Grossmann, V, Okuno, Y., Bacher, U., Nagae, G., Schnittger, S., Sanada, M., Kon, A., Alpermann, T., et al. (2014) · Leukemia · doi:10.1038/leu.2013.336 · Cited by 1,532 · see citing works

Evolution and impact of subclonal mutations in chronic lymphocytic leukemia

Landau, D. A., Carter, S. L., Stojanov, P., McKenna, A., Stevenson, K., Lawrence, M. S., Sougnez, C., Stewart, C., Sivachenko, A., Wang, L., et al. (2013) · Cell · doi:10.1016/j.cell.2013.01.019 · Cited by 1,379 · see citing works

Polycomb silencers control cell fate, development and cancer

Sparmann, A., & van Lohuizen, M. (2006) · Nature reviews. Cancer · doi:10.1038/nrc1991 · Cited by 1,294 · see citing works

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

Mackay, A., Burford, A., Carvalho, D., Izquierdo, E., Fazal-Salom, J., Taylor, K. R., Bjerke, L., Clarke, M., Vinci, M., Nandhabalan, M., et al. (2017) · Cancer Cell · doi:10.1016/j.ccell.2017.08.017 · Cited by 1,212 · see citing works

Genome Regulation by Polycomb and Trithorax: 70 Years and Counting

Schuettengruber, B., Bourbon, H.-M., Di Croce, L., & Cavalli, G. (2017) · Cell · doi:10.1016/j.cell.2017.08.002 · Cited by 1,094 · see citing works

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

Kool, M., Korshunov, A., Remke, M., Jones, D., Schlanstein, M., Northcott, P. A., Cho, Y., Köster, J., Meeteren, A. Y. N. S., van Vuurden, D. G., et al. (2012) · Acta Neuropathologica · doi:10.1007/s00401-012-0958-8 · Cited by 1,057 · see citing works

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Sturm, D., Orr, B. A., Toprak, U. H., Hovestadt, V., Jones, D., Capper, D., Sill, M., Buchhalter, I., Northcott, P. A., Irina, L., et al. (2016) · Cell · doi:10.1016/j.cell.2016.01.015 · Cited by 979 · see citing works

Transcriptional regulation by Polycomb group proteins

Di Croce, L., & Helin, K. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2669 · Cited by 864 · see citing works

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

Gao, Z., Zhang, J., Bonasio, R., Strino, F., Sawai, A., Parisi, F., Kluger, Y., & Reinberg, D. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.01.002 · Cited by 852 · see citing works

Dissecting the genomic complexity underlying medulloblastoma

Jones, D. T. W., Jäger, N., Kool, M., Zichner, T., Hutter, B., Sultan, M., Cho, Y.-J., Pugh, T. J., Hovestadt, V., Stütz, A. M., et al. (2012) · Nature · doi:10.1038/nature11284 · Cited by 839 · see citing works

Non-coding recurrent mutations in chronic lymphocytic leukaemia

Puente, X. S., Beà, S., Valdés‐Mas, R., Villamor, N., Gutiérrez‐Abril, J., Martín-Subero, J. I., Munar, M., Rubio-Pérez, C., Jares, P., Aymerich, M., et al. (2015) · Nature · doi:10.1038/nature14666 · Cited by 813 · see citing works

Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2

Knutson, S. K., Warholic, N. M., Wigle, T. J., Klaus, C. R., Allain, C. J., Raimondi, A., Scott, M. P., Chesworth, R., Moyer, M. P., Copeland, R. A., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1303800110 · Cited by 794 · see citing works

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.Preprint

van der Lugt, N. M. T., Domen, J., Linders, K., van ROON, M. A., Robanus-Maandag, E. C., Riele, H. T., van der Valk, M., Deschamps, J., Sofroniew, M. V., & van Lohuizen, M. (1994) · Genes & Development · doi:10.1101/gad.8.7.757 · Cited by 781 · see citing works

Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

Kool, M., Jones, D., Jäger, N., Northcott, P. A., Pugh, T. J., Hovestadt, V., Piro, R. M., Esparza, L. A., Markant, S. L., Remke, M., et al. (2014) · Cancer Cell · doi:10.1016/j.ccr.2014.02.004 · Cited by 756 · see citing works

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

Pugh, T. J., Weeraratne, S. D., Archer, T. C., Pomeranz Krummel, D. A., Auclair, D., Bochicchio, J., Carneiro, M. O., Carter, S. L., Cibulskis, K., Erlich, R. L., et al. (2012) · Nature · doi:10.1038/nature11329 · Cited by 750 · see citing works

Comprehensive Genomic Analysis of Rhabdomyosarcoma Reveals a Landscape of Alterations Affecting a Common Genetic Axis in Fusion-Positive and Fusion-Negative Tumors

Shern, J. F., Chen, L., Chmielecki, J., Wei, J. S., Patidar, R., Rosenberg, M. W., Ambrogio, L., Auclair, D., Wang, J., Song, Y. K., et al. (2014) · Cancer Discovery · doi:10.1158/2159-8290.cd-13-0639 · Cited by 742 · see citing works

Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

Blackledge, N. P., Farcas, A. M., Kondo, T., King, H. W., McGouran, J. F., Hanssen, L. L. P., Ito, S., Cooper, S., Kondo, K., Koseki, Y., et al. (2014) · Cell · doi:10.1016/j.cell.2014.05.004 · Cited by 734 · see citing works

Medulloblastomics: the end of the beginning

Northcott, P. A., Jones, D., Kool, M., Robinson, G. W., Gilbertson, R. J., Cho, Y., Pomeroy, S. L., Korshunov, A., Lichter, P., Taylor, M. D., et al. (2012) · Nature reviews. Cancer · doi:10.1038/nrc3410 · Cited by 661 · see citing works

Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

Yoshizato, T., Dumitriu, B., Hosokawa, K., Makishima, H., Yoshida, K., Townsley, D., Sato-Otsubo, A., Sato, Y., Liu, D., Suzuki, H., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1414799 · Cited by 646 · see citing works

Hierarchical Recruitment of Polycomb Group Silencing Complexes

Wang, L., Brown, J. L., Cao, R., Zhang, Y., Kassis, J. A., & Jones, R. S. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.05.009 · Cited by 562 · see citing works

Non-coding recurrent mutations in chronic lymphocytic leukaemia

Puente, X. S., Beà, S., Valdés‐Mas, R., Villamor, N., Gutiérrez‐Abril, J., Martín-Subero, J. I., Munar, M., Rubio-Pérez, C., Jares, P., Aymerich, M., et al. (2016) · Nature · doi:10.1038/nature18910 · Cited by 546 · see citing works

Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia

Metzeler, K. H., Herold, T., Rothenberg-Thurley, M., Amler, S., Sauerland, M. C., Görlich, D., Schneider, S., Konstandin, N. P., Dufour, A., Bräundl, K., et al. (2016) · Blood · doi:10.1182/blood-2016-01-693879 · Cited by 529 · see citing works

Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes

MacKintosh, C. (2004) · Biochemical Journal · doi:10.1042/bj20031332 · Cited by 527 · see citing works

A novel retinoblastoma therapy from genomic and epigenetic analyses

Zhang, J., Benavente, C. A., McEvoy, J. D., Flores‐Otero, J., Ding, L., Chen, X. '., Ulyanov, A. V., Wu, G., Wilson, M. W., Wang, J., et al. (2012) · Nature · doi:10.1038/nature10733 · Cited by 515 · see citing works

BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma.

French, C. A., Miyoshi, I., Kubonishi, I., Grier, H. E., Pérez‐Atayde, A. R., & Fletcher, J. A. (2003) · PubMed · Cited by 503 · see citing works

BCoR, a novel corepressor involved in BCL-6 repressionPreprint

Huynh, K. D., Fischle, W., Verdin, E. M., & Bardwell, V. J. (2000) · Genes & Development · doi:10.1101/gad.14.14.1810 · Cited by 475 · see citing works

A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion

Pierron, G., Tirode, F., Lucchesi, C., Reynaud, S., Ballet, S., Cohen‐Gogo, S., Perrin, V., Coindre, J., & Delattre, O. (2012) · Nature Genetics · doi:10.1038/ng.1107 · Cited by 475 · see citing works

KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

Farcas, A. M., Blackledge, N. P., Sudbery, I. M., Long, H. K., McGouran, J. F., Rose, N. R., Lee, S., Sims, D., Cerase, A., Sheahan, T. W., et al. (2012) · eLife · doi:10.7554/elife.00205 · Cited by 472 · see citing works

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression

Kalb, R., Latwiel, S., Baymaz, H. I., Jansen, P. W. T. C., Müller, C. W., Vermeulen, M., & Müller, J. (2014) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2833 · Cited by 451 · see citing works

Landscape Of Genetic Lesions In 944 Patients With Myelodysplastic Syndromes

Nagata, Y., Grossmann, V., Okuno, Y., Bacher, U., Nagae, G., Schnittger, S., Shiozawa, Y., Kon, A., Alpermann, T., Yoshida, K., et al. (2013) · Blood · doi:10.1182/blood.v122.21.521.521 · Cited by 430 · see citing works

Clear Cell Sarcoma of the Kidney

Argani, P., Perlman, E. J., Breslow, N. E., Browning, N. G., Green, D. M., D’Angio, G. J., & Beckwith, J. B. (2000) · The American Journal of Surgical Pathology · doi:10.1097/00000478-200001000-00002 · Cited by 374 · see citing works

Targeting Polycomb systems to regulate gene expression: modifications to a complex story

Blackledge, N. P., Rose, N. R., & Klose, R. J. (2015) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm4067 · Cited by 370 · see citing works

Polycomb Group and SCF Ubiquitin Ligases Are Found in a Novel BCOR Complex That Is Recruited to BCL6 Targets

Gearhart, M. D., Corcoran, C. M., Wamstad, J. A., & Bardwell, V. J. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00630-06 · Cited by 352 · see citing works

Transcriptomic definition of molecular subgroups of small round cell sarcomas

Watson, S., Perrin, V., Guillemot, D., Reynaud, S., Coindre, J., Karanian, M., Guinebretière, J., Fréneaux, P., Loarer, F. L., Bouvet, M., et al. (2018) · The Journal of Pathology · doi:10.1002/path.5053 · Cited by 335 · see citing works

Divergent clonal selection dominates medulloblastoma at recurrence

Morrissy, A. S., Garzia, L., Shih, D. J. H., Zuyderduyn, S., Huang, X., Skowron, P., Remke, M., Cavalli, F. M. G., Ramaswamy, V., Lindsay, P. E., et al. (2016) · Nature · doi:10.1038/nature16478 · Cited by 329 · see citing works

Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR

Ng, D., Thakker, N., Corcoran, C. M., Donnai, D., Perveen, R., Schneider, A. S., Hadley, D. W., Tifft, C. J., Zhang, L., Wilkie, A. O. M., et al. (2004) · Nature Genetics · doi:10.1038/ng1321 · Cited by 320 · see citing works

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

Gaidzik, V. I., Teleanu, V., Papaemmanuil, E., Weber, D., Paschka, P., Hahn, J., Wallrabenstein, T., Kolbinger, B., Köhne, C.-H., Horst, H. A., et al. (2016) · Leukemia · doi:10.1038/leu.2016.126 · Cited by 278 · see citing works

A new world of Polycombs: unexpected partnerships and emerging functions

Schwartz, Y. B., & Pirrotta, V. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3603 · Cited by 277 · see citing works

BCOR-CCNB3 Fusion Positive Sarcomas

Kao, Y., Owosho, A. A., Sung, Y., Zhang, L., Fujisawa, Y., Lee, J., Wexler, L. H., Argani, P., Swanson, D. M., Dickson, B. C., et al. (2017) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000000965 · Cited by 275 · see citing works

Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype

Großmann, V., Tiacci, E., Holmes, A. B., Kohlmann, A., Martelli, M. P., Kern, W., Rosseto, A. S., Klein, H., Dugas, M., Schindela, S., et al. (2011) · Blood · doi:10.1182/blood-2011-07-365320 · Cited by 265 · see citing works

Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome

Kulasekararaj, A. G., Jiang, J., Smith, A., Mohamedali, A. M., Mian, S. A., Gandhi, S., Gäken, J. A., Czepulkowski, B. H., Marsh, J. C. W., & Mufti, G. J. (2014) · Blood · doi:10.1182/blood-2014-05-574889 · Cited by 265 · see citing works

A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton

Akasaka, T., Kanno, M., Balling, R., Mieza, M. A., Taniguchi, M., & Koseki, H. (1996) · Development · doi:10.1242/dev.122.5.1513 · Cited by 260 · see citing works

14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma

Lee, C., Ou, W., Mariño‐Enríquez, A., Zhu, M. J., Mayeda, M., Wang, Y., Guo, X., Brunner, A. L., Amant, F. C., French, C. A., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115528109 · Cited by 258 · see citing works

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis

Béguelin, W., Teater, M., Gearhart, M. D., Calvo Fernández, M. T., Goldstein, R. L., Cárdenas, M. G., Hatzi, K., Rosen, M., Shen, H., Corcoran, C. M., et al. (2016) · Cancer Cell · doi:10.1016/j.ccell.2016.07.006 · Cited by 254 · see citing works

Genetic alterations of the cohesin complex genes in myeloid malignancies

Thota, S., Viny, A. D., Makishima, H., Spitzer, B. G., Radivoyevitch, T., Przychodzen, B. P., Sekeres, M. A., Levine, R. L., & Maciejewski, J. P. (2014) · Blood · doi:10.1182/blood-2014-04-567057 · Cited by 247 · see citing works

Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients

Kihara, R., Nagata, Y., Kiyoi, H., Kato, T., Yamamoto, E., Suzuki, K., Chen, F., Asou, N., Ohtake, S., Miyawaki, S., et al. (2014) · Leukemia · doi:10.1038/leu.2014.55 · Cited by 242 · see citing works

Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial–mesenchymal transition

Zhao, S., Bellone, S., Lopez, S., Thakral, D., Schwab, C. L., English, D. P.-G., Black, J., Cocco, E., Choi, J., Zammataro, L. A., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1614120113 · Cited by 230 · see citing works

The Molecular Landscape of Recurrent and Metastatic Head and Neck Cancers

Morris, L. G. T., Chandramohan, R., West, L., Zehir, A., Chakravarty, D., Pfister, D. G., Wong, R. J., Lee, N. Y., Sherman, E. J., Baxi, S. S., et al. (2016) · JAMA Oncology · doi:10.1001/jamaoncol.2016.1790 · Cited by 224 · see citing works

BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders

Damm, F., Chesnais, V., Nagata, Y., Yoshida, K., Scourzic, L., Okuno, Y., Itzykson, R., Sanada, M., Shiraishi, Y., Gelsi‐Boyer, V., et al. (2013) · Blood · doi:10.1182/blood-2012-11-469619 · Cited by 217 · see citing works

BCOR Overexpression Is a Highly Sensitive Marker in Round Cell Sarcomas With BCOR Genetic Abnormalities

Kao, Y., Sung, Y., Zhang, L., Jungbluth, A. A., Huang, S., Argani, P., Agaram, N. P., Zin, A., Alaggio, R., & Antonescu, C. R. (2016) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000000697 · Cited by 208 · see citing works

Clonal hematopoiesis in acquired aplastic anemia

Ogawa, S. (2016) · Blood · doi:10.1182/blood-2016-01-636381 · Cited by 203 · see citing works

Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of Infancy

Kao, Y., Sung, Y., Zhang, L., Huang, S., Argani, P., Chung, C. T. ‐., Graf, N. S., Wright, D. C., Kellie, S. J., Agaram, N. P., et al. (2016) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000000629 · Cited by 202 · see citing works

Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics

Hoffman, L. M., DeWire, M. D., Ryall, S. T., Buczkowicz, P., Leach, J., Miles, L., Ramani, A. K., Brudno, M., Kumar, S. S., Drissi, R., et al. (2016) · Acta Neuropathologica Communications · doi:10.1186/s40478-015-0269-0 · Cited by 196 · see citing works

BCOR-CCNB3 (Ewing-like) Sarcoma

Puls, F., Niblett, A., Marland, G., Gaston, C. L., Douis, H., Mangham, D. C., Sumathi, V. P., & Kindblom, L. (2014) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000000223 · Cited by 190 · see citing works

Round cell sarcomas beyond E wing: emerging entities

Antonescu, C. R. (2013) · Histopathology · doi:10.1111/his.12281 · Cited by 188 · see citing works

Molecular architecture of polycomb repressive complexes

Chittock, E. C., Latwiel, S., Miller, T. C. R., & Müller, C. W. (2017) · Biochemical Society Transactions · doi:10.1042/bst20160173 · Cited by 187 · see citing works

ZC3H7B-BCOR high-grade endometrial stromal sarcomas: a report of 17 cases of a newly defined entity

Lewis, N. E., Soslow, R. A., DeLair, D. F., Park, K. J., Murali, R., Hollmann, T. J., Davidson, B., Micci, F., Panagopoulos, I., Hoang, L. N., et al. (2017) · Modern Pathology · doi:10.1038/modpathol.2017.162 · Cited by 183 · see citing works

Novel ZC3H7B‐BCOR, MEAF6‐PHF1, and EPC1‐PHF1 fusions in ossifying fibromyxoid tumors—molecular characterization shows genetic overlap with endometrial stromal sarcoma

Antonescu, C. R., Sung, Y., Chen, C., Zhang, L., Chen, H., Singer, S., Agaram, N. P., Sboner, A., & Fletcher, C. D. �. (2013) · Genes Chromosomes and Cancer · doi:10.1002/gcc.22132 · Cited by 182 · see citing works

Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma

Seki, M., Nishimura, R., Yoshida, K., Shimamura, T., Shiraishi, Y., Sato, Y., Kato, M., Chiba, K., Tanaka, H., Hoshino, N., et al. (2015) · Nature Communications · doi:10.1038/ncomms8557 · Cited by 177 · see citing works

Novel BCOR-MAML3 and ZC3H7B-BCOR Gene Fusions in Undifferentiated Small Blue Round Cell Sarcomas

Specht, K., Zhang, L., Sung, Y., Nucci, M. R., Dry, S., Vaiyapuri, S., Richter, G. H. S., Fletcher, C. D. �., & Antonescu, C. R. (2016) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000000591 · Cited by 176 · see citing works

Genetic alterations of JAK/STAT cascade and histone modification in extranodal NK/T-cell lymphoma nasal type

Lee, S., Park, H. Y., Kang, S. Y., Kim, S. J., Hwang, J., Lee, S., Kwak, S. H., Park, K. S., Yoo, H. Y., Kim, W. S., et al. (2015) · Oncotarget · doi:10.18632/oncotarget.3776 · Cited by 174 · see citing works

Clinical, immunophenotypic, cytogenetic, and molecular genetic features in 117 adult patients with mixed-phenotype acute leukemia defined by WHO-2008 classification

Yan, L., Ping, N., Zhu, M., Sun, A., Xue, Y., Ruan, C., Drexler, H. G., MacLeod, R. A. F., Wu, D., & Chen, S. (2012) · Haematologica · doi:10.3324/haematol.2012.064485 · Cited by 174 · see citing works

Consistent in-frame internal tandem duplications of BCOR characterize clear cell sarcoma of the kidney

Ueno‐Yokohata, H., Okita, H., Nakasato, K., Akimoto, S., Hata, J.-I., Koshinaga, T., Fukuzawa, M., & Kiyokawa, N. (2015) · Nature Genetics · doi:10.1038/ng.3338 · Cited by 173 · see citing works

Memories from the Polycomb Group Proteins

Lanzuolo, C., & Orlando, V. (2012) · Annual Review of Genetics · doi:10.1146/annurev-genet-110711-155603 · Cited by 171 · see citing works

Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney

Roy, A., Kumar, V., Zorman, B., Fang, E., Haines, K. M., Doddapaneni, H., Hampton, O. A., White, S. J., Bavle, A. A., Patel, N. R., et al. (2015) · Nature Communications · doi:10.1038/ncomms9891 · Cited by 161 · see citing works

PRC1 complex diversity: where is it taking us?

Gil, J., & O’Loghlen, A. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.06.005 · Cited by 160 · see citing works

BCOR Internal Tandem Duplication in High-grade Uterine Sarcomas

Mariño‐Enríquez, A., Lauria, A., Przybył, J., Ng, T., Kowalewska, M., Dêbiec‐Rychter, M., Ganesan, R., Sumathi, V. P., George, S., McCluggage, W. G., et al. (2017) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000000993 · Cited by 158 · see citing works

BCOR–CCNB3 fusions are frequent in undifferentiated sarcomas of male children

Peters, T., Kumar, V., Polikepahad, S., Lin, F. Y. H., Sarabia, S. F., Liang, Y., Wang, W., Lazar, A. J., Doddapaneni, H., Chao, H., et al. (2014) · Modern Pathology · doi:10.1038/modpathol.2014.139 · Cited by 157 · see citing works

Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis

van den Boom, V., Maat, H., Geugien, M., López, A. R., Sotoca, A. M., Jaques, J., Brouwers-Vos, A. Z., Fusetti, F., Groen, R. W. J., Yuan, H., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.12.034 · Cited by 156 · see citing works

Fusion of the ZC3H7B and BCOR genes in endometrial stromal sarcomas carrying an X;22‐translocation

Panagopoulos, I., Thorsen, J., Gorunova, L., Haugom, L., Bjerkehagen, B., Davidson, B., Heim, S., & Micci, F. (2013) · Genes Chromosomes and Cancer · doi:10.1002/gcc.22057 · Cited by 154 · see citing works

BCOR is a robust diagnostic immunohistochemical marker of genetically diverse high-grade endometrial stromal sarcoma, including tumors exhibiting variant morphology

Chiang, S., Lee, C., Stewart, C. J. R., Oliva, E., Hoang, L. N., Ali, R. H., Hensley, M. L., Arias‐Stella, J., Frosina, D., Jungbluth, A. A., et al. (2017) · Modern Pathology · doi:10.1038/modpathol.2017.42 · Cited by 149 · see citing works

BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia

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RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes

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Somatic genomic alterations in retinoblastoma beyond RB1 are rare and limited to copy number changes

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CNS high‐grade neuroepithelial tumor with BCOR internal tandem duplication: a comparison with its counterparts in the kidney and soft tissue

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A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs

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BCOR regulates myeloid cell proliferation and differentiation

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Primary Renal Sarcomas With BCOR-CCNB3 Gene Fusion

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Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets

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Genetic characterization of T‐PLL reveals two major biologic subgroups and JAK3 mutations as prognostic marker

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Development and Evaluation of a Pan-Sarcoma Fusion Gene Detection Assay Using the NanoString nCounter Platform

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Cytogenetic and molecular profile of endometrial stromal sarcoma

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Genes encoding members of the JAK ‐ STAT pathway or epigenetic regulators are recurrently mutated in T‐cell prolymphocytic leukaemia

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Massively Parallel Sequencing Identifies Recurrent Mutations in TP53 in Thymic Carcinoma Associated with Poor Prognosis

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Whole transcriptome sequencing identifies BCOR internal tandem duplication as a common feature of clear cell sarcoma of the kidney

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KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1

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Oculo‐facio‐cardio‐dental syndrome: Skewed X chromosome inactivation in mother and daughter suggest X‐linked dominant Inheritance

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BCOR internal tandem duplication and YWHAE–NUTM2B/E fusion are mutually exclusive events in clear cell sarcoma of the kidney

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Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene

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Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia

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Number of RUNX1 mutations, wild-type allele loss and additional mutations impact on prognosis in adult RUNX1-mutated AML

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Chromatin remodelling and DNA repair genes are frequently mutated in endometrioid endometrial carcinoma

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BCOR-CCNB3 Undifferentiated Sarcoma—Does Immunohistochemistry Help in the Identification?

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RoXaN, a Novel Cellular Protein Containing TPR, LD, and Zinc Finger Motifs, Forms a Ternary Complex with Eukaryotic Initiation Factor 4G and Rotavirus NSP3

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Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy

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Genomic Profile of Chronic Lymphocytic Leukemia in Korea Identified by Targeted Sequencing

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A Novel POK Family Transcription Factor, ZBTB5, Represses Transcription of p21CIP1 Gene

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Chromothripsis Is a Recurrent Genomic Abnormality in High-Risk Myelodysplastic Syndromes

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Whole Genome and Transcriptome Sequencing of a B3 Thymoma

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Successful Treatment of Recurrent Primitive Myxoid Mesenchymal Tumor of Infancy WithBCORInternal Tandem Duplication

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Successful treatment of acute promyelocytic leukemia with a t(X;17)(p11.4;q21) and BCOR-RARA fusion gene

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Personalized oncogenomic analysis of metastatic adenoid cystic carcinoma: using whole-genome sequencing to inform clinical decision-makingPreprint

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Round Cell Tumors of Bone

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ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/ RUNX1‐RUNX1T1 and associated with a better prognosis

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Evaluation and Diagnosis of Central Nervous System Embryonal Tumors (Non-Medulloblastoma)

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Mutations in KMT2C, BCOR and KDM5C Predict Response to Immune Checkpoint Blockade Therapy in Non-Small Cell Lung Cancer

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BCOR-coupled H2A monoubiquitination represses a subset of androgen receptor target genes regulating prostate cancer proliferation

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A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups

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DNA damage repair proteins across the Tree of Life

Nischwitz, E., Schoonenberg, V. A. C., Fradera-Sola, A., Dejung, M., Vydzhak, O., Levin, M., Luke, B. T., Butter, F., & Scheibe, M. (2023) · iScience · doi:10.1016/j.isci.2023.106778 · Cited by 10 · see citing works

Genome‐wide CRISPR/Cas9 knockout screening to mitigate cell growth inhibition induced by histone deacetylase inhibitors in recombinant CHO cells

Kim, D., Kim, S. H., Yoon, C., & Lee, G. (2023) · Biotechnology and Bioengineering · doi:10.1002/bit.28611 · Cited by 10 · see citing works

Pediatric Soft Tissue Tumors With BCOR ITD Express EGFR but Not OLIG2

Salgado, C. M., Zin, A., Garrido‐Pontnou, M., Kletskaya, I. S., Vito, R. D., Reyes‐Múgica, M., Bisogno, G., Donofrio, V., & Alaggio, R. (2020) · Pediatric and Developmental Pathology · doi:10.1177/1093526620945528 · Cited by 10 · see citing works

CNS tumors with YWHAE:NUTM2 and KDM2B-fusions present molecular similarities to extra-CNS tumors having BCOR internal tandem duplication or alternative fusions

Tauziède‐Espariat, A., Pierron, G., Guillemot, D., Bochaton, D., Watson, S., Masliah‐Planchon, J., Vasiljevic, A., Meurgey, A., Chotard, G., Hasty, L., et al. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01279-3 · Cited by 9 · see citing works

Detection of driver mutations and genomic signatures in endometrial cancers using artificial intelligence algorithms

Stan, A. L., Bosart, K., Kaur, M., Vo, M., Escorcia, W., Yoder, R. J., Bouley, R. A., & Petreaca, R. C. (2024) · PLoS ONE · doi:10.1371/journal.pone.0299114 · Cited by 9 · see citing works

Whole-exome Sequencing of Atypical Parathyroid Tumors Detects Novel and Common Genes Linked to Parathyroid Tumorigenesis

Pardi, E., Poma, A. M., Torregrossa, L., Pierotti, L., Borsari, S., Valentina, S. D., Marcocci, C., & Cetani, F. (2024) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae441 · Cited by 8 · see citing works

JAZF1, YWHAE and BCOR gene translocation in primary extrauterine low‐grade and high‐grade endometrial stromal sarcomas

Sun, L., Zhao, W., Zhao, Z., & Zhu, Y. (2021) · Histopathology · doi:10.1111/his.14608 · Cited by 8 · see citing works

Progression of prostate cancer reprograms MYC-mediated lipid metabolism via lysine methyltransferase 2A

Whitlock, N. C., White, M. E., Capaldo, B. J., Ku, A. T., Agarwal, S., Fang, L., Wilkinson, S. C., Trostel, S. Y., Shi, Z.-D., Basuli, F., et al. (2022) · Discover Oncology · doi:10.1007/s12672-022-00565-3 · Cited by 8 · see citing works

Functional impact of multi-omic interactions in breast cancer subtypes

Ochoa, S., & Lemus, E. H. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2022.1078609 · Cited by 9 · see citing works

Strategies for the Treatment of Infantile Soft Tissue Sarcomas With BCOR Alterations

Merjaneh, N., Kim, H. J., Escoto, H., Metts, J. L., Ray, A., Bukowinski, A., LeBlanc, Z., Fair, D. B., Watanbe, M., Alva, E. D., et al. (2023) · Journal of Pediatric Hematology/Oncology · doi:10.1097/mph.0000000000002620 · Cited by 8 · see citing works

A Case Series of BCOR Sarcomas With a New Splice Variant of BCOR/CCNB3 Fusion Gene

Kyriazoglou, A. I., Tourkantoni, N., Liontos, M., Zagouri, F., Mahaira, L. G., PAPAKOSTA, A., MICHALI, D., Patereli, A., Stefanaki, K. S., Tzotzola, V., et al. (2020) · In Vivo · doi:10.21873/invivo.12125 · Cited by 8 · see citing works

Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomas

Imle, R., Blösel, D., Kommoss, F. K. F., Placke, S., Stutheit-Zhao, E., Blume, C., Lupar, D., Schmitt, L., Winter, C., Wagner, L., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60519-5 · Cited by 9 · see citing works

Molecular Identification and In Silico Protein Analysis of a Novel BCOR-CLGN Gene Fusion in Intrathoracic BCOR-Rearranged Sarcoma

Chien, Y.-C. C., Madarász, K., Csoma, S. L., Mótyán, J. A., Huang, H., Méhes, G., & Mokánszki, A. (2023) · Cancers · doi:10.3390/cancers15030898 · Cited by 7 · see citing works

Assessment of Genetic Stability in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Using Droplet Digital PCR

Park, J. W., Bae, S. J., Yun, J. H., Kim, S., & Park, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25021101 · Cited by 8 · see citing works

BCOR::CREBBP fusion in malignant neuroepithelial tumor of CNS expands the spectrum of methylation class CNS tumor with BCOR/BCOR(L1)-fusion

Ebrahimi, A., Waha, A., Schittenhelm, J., Gohla, G., Schuhmann, M. U., & Pietsch, T. (2024) · Acta Neuropathologica Communications · doi:10.1186/s40478-024-01780-5 · Cited by 7 · see citing works

The clinical, morphological, and genetic heterogeneity of endometrial stromal sarcoma

Davidson, B., Matías‐Guiu, X., & Lax, S. (2020) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-020-02762-3 · Cited by 7 · see citing works

The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cellsPreprint

Fang, J., Fang, J., Singh, S., Wells, B., Wu, Q., Jin, H., Janke, L., Wan, S., Steele, J. A., Connelly, J. P., et al. (2025) · eLife · doi:10.7554/elife.101299.3 · Cited by 8 · see citing works

Comprehensive bioinformatics analysis of MEX3 family genes in hepatocellular carcinoma

Zhang, X., Sun, P., Chu, T., Feng, Y., & Zhang, X. (2025) · Scientific Reports · doi:10.1038/s41598-025-02057-0 · Cited by 6 · see citing works

Description of a Novel ERBB4-rearranged Uterine Sarcoma

Lim, S. H., Mansor, S., Kathirvel, R., Kuick, C. H., Lim-Tan, S. K., & McCluggage, W. G. (2021) · International Journal of Gynecological Pathology · doi:10.1097/pgp.0000000000000826 · Cited by 6 · see citing works

An Unusual Endometrial Stromal Neoplasm With JAZF1-BCORL1 Rearrangement

Moghaddam, P. A., Young, R. H., Ismiil, N. D., Bennett, J. A., & Oliva, E. (2023) · International Journal of Gynecological Pathology · doi:10.1097/pgp.0000000000000941 · Cited by 6 · see citing works

The utility of FISH analysis in the diagnosis of BCOR-rearranged sarcomas

Cocchi, S., Gambarotti, M., Gamberi, G., Magagnoli, G., Maioli, M., Stevanin, M., Samperi, F., Righi, A., & Benini, S. (2024) · Pathology - Research and Practice · doi:10.1016/j.prp.2024.155209 · Cited by 6 · see citing works

Genotypes versus phenotypes: The potential paradigm shift in the diagnosis and management of pediatric neoplasms

Chan, G., & Chan, C. M. (2020) · Pediatric Investigation · doi:10.1002/ped4.12211 · Cited by 6 · see citing works

Mouse Models of Frequently Mutated Genes in Acute Myeloid Leukemia

Mohanty, S., & Heuser, M. (2021) · Cancers · doi:10.3390/cancers13246192 · Cited by 6 · see citing works

Clinicopathologic and molecular analysis of aBCOR–CCNB3undifferentiated sarcoma of the kidney reveals significant epigenetic alterationsPreprint

Hagoel, T. J., Gomez, E. C., Gupta, A. K., Twist, C. J., Kozielski, R., Martin, J. C., Gao, L., Kuechle, J., Singh, P. K., Lynch, M. L., et al. (2021) · Molecular Case Studies · doi:10.1101/mcs.a005942 · Cited by 6 · see citing works

Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR–ncPRC1.1Preprint

van der Meer, J. W., Larue, A., van der Knaap, J. A., Chalkley, G. E., Sijm, A., Beikmohammadi, L., Kozhevnikova, E. N., van der Vaart, A., Tilly, B. C., Bezstarosti, K., et al. (2025) · Genes & Development · doi:10.1101/gad.352272.124 · Cited by 6 · see citing works

Osteosarcoma’s genetic landscape painted by genes’ mutations

Urban, W., Krzystańska, D., Piekarz, M., Nazar, J., & Jankowska, A. (2023) · Acta Biochimica Polonica · doi:10.18388/abp.2020_6869 · Cited by 5 · see citing works

BCOR abnormalities in endometrial stromal sarcoma

Fayoumi, A. (2025) · Gynecologic Oncology Reports · doi:10.1016/j.gore.2024.101672 · Cited by 5 · see citing works

Mesonephric-like adenocarcinoma of the endometrium: detailed molecular characterization of the first case showing a morphological continuum from mesonephric-like metaplasia and atypical mesonephric-like hyperplasia to adenocarcinoma

Santoro, A., Angelico, G., Narducci, N., Travaglino, A., Piermattei, A., Inzani, F. S., Arciuolo, D., Addante, F., Urtueta, B. P., Tinnirello, G., et al. (2025) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-024-03972-9 · Cited by 5 · see citing works

Molecular Diversity of Embryonic-Type Neuroectodermal Tumors Arising From Testicular Germ Cell Tumors

Zong, Y., Huang, R., Bitar, M., Drakaki, A., Zhang, L., Lin, D. I., & Ye, H. (2024) · Modern Pathology · doi:10.1016/j.modpat.2024.100702 · Cited by 5 · see citing works

BCOR-CCNB3 Sarcoma with Prominent Rhabdoid Cells Mimicking Rhabdomyoblasts: Expanding the Morphologic spectrum of BCOR-CCNB3 Sarcoma

Cai, Z., Duncan, D., Li, R., Thomas, J. O., & Zhu, H. (2021) · International Journal of Surgical Pathology · doi:10.1177/10668969211013891 · Cited by 5 · see citing works

BCOR Internal Tandem Duplication Associated Uterine Sarcoma: Expanding the Clinicopathologic Spectrum

Thiryayi, S. A., Ettler, H. C., Goebel, E. A., Préfontaine, M., Paton, T., Wong, A., Yee, D., Agro, E., Mayers, J. G., Lerner‐Ellis, J. P., et al. (2021) · International Journal of Gynecological Pathology · doi:10.1097/pgp.0000000000000822 · Cited by 5 · see citing works

Infantile Fibrosarcoma and Other Spindle Cell Neoplasms of Infancy. A Review of Morphologically Overlapping yet Molecularly Distinctive Entities

Jabbari, S., Salari, B., He, M., & Dehner, L. P. (2022) · Fetal and Pediatric Pathology · doi:10.1080/15513815.2021.2024631 · Cited by 4 · see citing works

Outcomes of children with clear cell sarcoma of kidney following NWTS strategies in Shanghai China (2003–2021)

Zhang, A., Yuan, X., Jiang, S., Xu, D., Huang, C., Tang, J. Y., & Gao, Y. (2024) · PLoS ONE · doi:10.1371/journal.pone.0306863 · Cited by 4 · see citing works

Exploring the molecular insights of concurrent composite mucoepidermoid carcinoma and papillary thyroid carcinoma

Falcone, R., Sponziello, M., Carletti, R., Gioia, C. R. T. D., Nardi, F., Mio, C., Pecce, V., Abballe, L., Grani, G., Ramundo, V., et al. (2020) · Endocrine · doi:10.1007/s12020-020-02221-8 · Cited by 4 · see citing works

Epigenetic Deregulation by BCOR Oncogenic Fusions in Sarcomas

Pejkovska, A. (2024) · heiDOK (Heidelberg University) · doi:10.11588/heidok.00035218

Abstract 6168: Investigating the mechanism of oncogenesis of BCOR-CCNB3 fusion positive sarcomas

Pete, V. A., Shirai, R., Hakim, S., Broadman, J., Oike, N., Goodspeed, A. E., & Hayashi, M. (2026) · Cancer Research · doi:10.1158/1538-7445.am2026-6168

BCOR Biology in Development and Cancer

Royston, H. N., Taddia, A., Santori, F. R., Ivanova, N., & Funato, K. (2026) · Cells · doi:10.3390/cells15201856

Gene of the month: BCOR

Aldera, A. P., & Govender, D. (2020) · Journal of Clinical Pathology · doi:10.1136/jclinpath-2020-206513 · Cited by 29 · see citing works

A Pan-Cancer Landscape Analysis Reveals a Subset of Endometrial Stromal and Pediatric Tumors Defined by Internal Tandem Duplications of BCOR

Juckett, L. T., Lin, D. I., Madison, R. W., Ross, J. S., Schrock, A. B., & Ali, S. M. (2018) · Oncology · doi:10.1159/000493322 · Cited by 46 · see citing works