Cited by 146Electroconvulsive Therapy StudiesTreatment of Major DepressionTranscranial Magnetic Stimulation Studies

Current electroconvulsive therapy practice and research in the geriatric population

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Kerner, Nancy, Prudic, Joan·2014·Neuropsychiatry

Abstract

Electroconvulsive therapy (ECT) is utilized worldwide for various severe and treatment-resistant psychiatric disorders. Research studies have shown that ECT is the most effective and rapid treatment available for elderly patients with depression, bipolar disorder and psychosis. For patients who suffer from intractable catatonia and neuroleptic malignant syndrome, ECT can be life saving. For elderly patients who cannot tolerate or respond poorly to medications and who are at a high risk for drug-induced toxicity or toxic drug interactions, ECT is the safest treatment option. Organic causes are frequently associated with late-life onset of neuropsychiatric conditions, such as parkinsonism, dementia and stroke. ECT has proven to be efficacious even when these conditions are present. During the next decade, research studies should focus on the use of ECT as a synergistic therapy, to enhance other biological and psychological treatments, and prevent symptom relapse and recurrence.

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  • ECT is safe and effective in LLD accompanied by Parkinsonism, dementia, and stroke.

    “ECT is safe and effective in LLD accompanied by Parkinsonism, dementia, and stroke157.”

    From Mechanisms and treatment of late-life depression (2019) · cites this paper as [157]

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Research works printed but not linked: 2

  1. [105]Mukherjee S Sackeim HA Schnur DB Electroconvulsive therapy of acute manic episodes: a review of 50 years’ experience Am. J. Psychiatry 1994 151 2 169 176 8296883
  2. [142]Koek RJ Mervis JR Treatment-refractory catatonia, ECT, and parenteral lorazepam Am. J. Psychiatry 1999 156 1 160 161 author reply 161 9892323

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Authors
Kerner, N., & Prudic, J.
Affiliations
New York State Psychiatric Institute (US)
Corresponding author
Kerner, Nancy
Venue
Neuropsychiatry
Published
2014-02
Volume
4
Issue
1
Pages
33-54
ISSN
1758-2008 (ISSN-L)
OpenAlex
W2090911922
Cited by
146
References
267
Citations by year
2026: 8 · 2025: 8 · 2024: 14 · 2023: 14 · 2022: 16 · 2021: 24 · 2020: 9 · 2019: 18 · 2018: 10 · 2017: 13 · 2016: 4 · 2015: 6 · 2014: 1 · 2013: 1
FWCI
6.05
Type
journal article
Language
en
Open access
Locations
  • Neuropsychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • Columbia Academic Commons (Columbia University)
Funders
National Institute of Mental Health (T32MH020004)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
Keywords
electroconvulsive therapy, elderly patients, geriatric depression, bipolar disorder, psychosis, catatonia, neuroleptic malignant syndrome, treatment-resistant psychiatric disorders, parkinsonism, dementia, stroke, drug toxicity, relapse prevention, synergistic therapy

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