The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.
Updates on the Epidemiology of Age-Related Macular Degeneration
Abstract
This meta-analysis reports on current estimates of the prevalence of age-related macular degeneration (AMD) based on a review of recent meta-analyses and literature research. Within an age of 45-85 years, global prevalences of any AMD, early AMD, and late AMD were 8.7% [95% credible interval (CrI), 4.3‒17.4], 8.0% (95% CrI, 4.0‒15.5), and 0.4% (95% CrI, 0.2-0.8). Early AMD was more common in individuals of European ancestry (11.2%) than in Asians (6.8%), whereas prevalence of late AMD did not differ significantly. AMD of any type was less common in individuals of African ancestry. The number of individuals with AMD was estimated to be 196 million (95% CrI, 140‒261) in 2020 and 288 million (95% CrI, 205‒399) in 2040. The worldwide number of persons blind (presenting visual acuity < 3/60) or with moderate to severe vision impairment (MSVI; presenting visual acuity < 6/18 to 3/60 inclusive) due to macular disease in 2010 was 2.1 million [95% uncertainty interval (UI), 1.9‒2.7] individuals out of 32.4 million individuals blind and 6.0 million (95% UI, 5.2‒8.1) persons out of 191 million people with MSVI. Age-standardized prevalence of macular diseases as cause of blindness in adults aged 50+ years worldwide decreased from 0.2% (95% UI, 0.2‒0.2) in 1990 to 0.1% (95% UI, 0.1‒0.2) in 2010; as cause for MSVI, it remained mostly unchanged (1990: 0.4%; 95% UI, 0.3‒0.5; 2010: 0.4%; 95% UI, 0.4‒0.6), with no significant sex difference. In 2015, AMD was the fourth most common cause of blindness globally (in approximately 5.8% of blind individuals) and third most common cause for MSVI (3.9%). These data show the globally increasing importance of AMD.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Murray, C. J. L., Vos, T., Lozano, R., Naghavi, M., Flaxman, A. D., Michaud, C., Ezzati, M., Shibuya, K., Salomon, J. A., Abdalla, S., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61689-4 · Cited by 8,888
Self-citationRanibizumab for Neovascular Age-Related Macular Degeneration
Rosenfeld, P. J., Brown, D. M., Heier, J. S., Boyer, D. S., Kaiser, P. K., Chung, C. Y., & Kim, R. Y. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa054481 · Cited by 5,886
Wong, W. L., Su, X., Li, X., Cheung, C. M. G., Klein, R., Cheng, C.-Y., & Wong, T. Y. (2014) · The Lancet Global Health · doi:10.1016/s2214-109x(13)70145-1 · Cited by 5,331
Bourne, R. R. A., Flaxman, S. R., Braithwaite, T., Cicinelli, M. V., Das, A., Jonas, J. B., Keeffe, J., Kempen, J. H., Leasher, J., Limburg, H., et al. (2017) · The Lancet Global Health · doi:10.1016/s2214-109x(17)30293-0 · Cited by 2,213
Prevalence of age-related maculopathy
Klein, R., Klein, B. E. K., & Linton, K. L. P. (1992) · Ophthalmology · doi:10.1016/s0161-6420(92)31871-8 · Cited by 1,845
Causes of vision loss worldwide, 1990–2010: a systematic analysis
Bourne, R. R. A., Stevens, G. A., White, R. A., Smith, J. L., Flaxman, S. R., Price, H., Jonas, J. B., Keeffe, J., Leasher, J., Naidoo, K., et al. (2013) · The Lancet Global Health · doi:10.1016/s2214-109x(13)70113-x · Cited by 1,831
Age-related macular degeneration
Lim, L. S., Mitchell, P., Seddon, J. M., Holz, F. G., & Wong, T. Y. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60282-7 · Cited by 1,717
Risk factors for age-related macular degeneration
Smith, W., Assink, J., Klein, R., Mitchell, P., Klaver, C. C. W., Klein, B. E. K., Hofman, A., Jensen, S., Wang, J. J., & de Jong, P. T. V. M. (2001) · Ophthalmology · doi:10.1016/s0161-6420(00)00580-7 · Cited by 1,071
Prevalence of age-related maculopathy in Australia
Mitchell, P., Smith, W., Attebo, K., & Wang, J. J. (1995) · Ophthalmology · doi:10.1016/s0161-6420(95)30846-9 · Cited by 1,062
Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis
Chakravarthy, U., Wong, T. Y., Fletcher, A., Piault, E., Evans, C., Zlateva, G., Buggage, R., Pleil, A., & Mitchell, P. (2010) · BMC Ophthalmology · doi:10.1186/1471-2415-10-31 · Cited by 842
Research works printed but not linked: 6
- 10.1111/j.1755-3768.1990.tb04786.x · doi:10.1111/j.1755-3768.1990.tb04786.x
- 10.1186/1471-2415-11-10 · doi:10.1186/1471-2415-11-10
- 10.1136/bjophthalmol-2013-304047 · doi:10.1136/bjophthalmol-2013-304047
- 10.1136/bjophthalmol-2013-303998 · doi:10.1136/bjophthalmol-2013-303998
- 10.1136/bjophthalmol-2013-304013 · doi:10.1136/bjophthalmol-2013-304013
- 10.1016/j.ajo.2007.03.047 · DOI · Paper page
Cited by
Dugel, P. U., Singh, R. P., Koh, A., Ogura, Y., Weissgerber, G., Gedif, K., Jaffe, G. J., Tadayoni, R., Schmidt-Erfurth, U., & Holz, F. G. (2021) · Ophthalmology · doi:10.1016/j.ophtha.2020.06.028 · Cited by 373
Pogue, A. I., & Lukiw, W. J. (2018) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-017-0572-3 · Cited by 105
HSP90 acts as a senomorphic target in senescent retinal pigmental epithelial cells
Chen, D.-D., Peng, X., Wang, Y., Jiang, M., Xue, M., Shang, G., Liu, X., Jia, X., Liu, B., Lu, Y., et al. (2021) · Aging · doi:10.18632/aging.203496 · Cited by 38
Calton, M. A., Croze, R. H., Burns, C., Beliakoff, G., Vazin, T., Szymanski, P., Schmitt, C., Klein, A., Leong, M., Quezada, M., et al. (2024) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.65.14.1 · Cited by 21
Burden of Disease Study of Patients with Neovascular Age-Related Macular Degeneration in Spain
Abraldes, M. J., Calvo, P., Gámez Lechuga, M., Merino, M., Martín Lorenzo, T., Maravilla-Herrera, P., Gil Jiménez, B., & Ruiz-Moreno, J. M. (2024) · Ophthalmology and Therapy · doi:10.1007/s40123-024-00960-9 · Cited by 6
Metadata
- Venue
- Asia-Pacific Journal of Ophthalmology
- Published
- 2017
- Volume
- 6
- Issue
- 6
- Pages
- 493-497
- ISSN
- 2162-0989 (ISSN-L)
- OpenAlex
- W2969630964
- Cited by
- 266
- References
- 59
- FWCI
- 12.15
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Updates on the Epidemiology of Age-Related Macular Degeneration. https://app.cochat.ai/papers/10.22608/apo.2017251
- The paper
- Updates on the Epidemiology of Age-Related Macular Degeneration. (2017). Asia-Pacific Journal of Ophthalmology. https://doi.org/10.22608/apo.2017251
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
