Cited by 524Pancreatic and Hepatic Oncology ResearchMetabolism, Diabetes, and CancerPancreatitis Pathology and Treatment

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Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer

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Andersen, Dana K., Korc, Murray, Petersen, Gloria M., Eibl, Guido, Li, Donghui, Rickels, Michael R., Chari, Suresh T., Abbruzzese, James L.·2017·Diabetes

DOI 10.2337/db16-1477PMC PMC5399609

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Abstract

The relationships between diabetes and pancreatic ductal adenocarcinoma (PDAC) are complex. Longstanding type 2 diabetes (T2DM) is a risk factor for pancreatic cancer, but increasing epidemiological data point to PDAC as also a cause of diabetes due to unknown mechanisms. New-onset diabetes is of particular interest to the oncology community as the differentiation of new-onset diabetes caused by PDAC as distinct from T2DM may allow for earlier diagnosis of PDAC. To address these relationships and raise awareness of the relationships between PDAC and diabetes, a symposium entitled Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer was held at the American Diabetes Association’s 76th Scientific Sessions in June 2016. This article summarizes the data presented at that symposium, describing the current understanding of the interrelationships between diabetes, diabetes management, and pancreatic cancer, and identifies areas where additional research is needed.

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Goossens, G. H. (2017) · Obesity Facts · doi:10.1159/000471488 · Cited by 8,481
Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Rahib, L., Smith, B. D., Aizenberg, R., Rosenzweig, A. B., Fleshman, J. M., & Matrisian, L. M. (2014) · Cancer Research · doi:10.1158/0008-5472.can-14-0155 · Cited by 7,094
Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012
Menke, A., Casagrande, S., Geiss, L., & Cowie, C. C. (2015) · JAMA · doi:10.1001/jama.2015.10029 · Cited by 2,362
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes
Kahn, S. E. (2003) · Diabetologia · doi:10.1007/s00125-002-1009-0 · Cited by 2,166 · cited 1×
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Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
Wellcome Trust Case Control Consortium, Zeggini, E., Scott, L. J., Saxena, R., Voight, B. F., Marchini, J. L., Hu, T., de Bakker, P. I., Abecasis, G. R., Almgren, P., et al. (2008) · Nature Genetics · doi:10.1038/ng.120 · Cited by 1,864
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
Madiraju, A. K., Erion, D. M., Rahimi, Y., Zhang, X.-M., Braddock, D. T., Albright, R. A., Prigaro, B. J., Wood, J. L., Bhanot, S., MacDonald, M. J., et al. (2014) · Nature · doi:10.1038/nature13270 · Cited by 1,284
The genetic architecture of type 2 diabetes
Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., et al. (2016) · Nature · doi:10.1038/nature18642 · Cited by 1,051
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Jones, S., Hruban, R. H., Kamiyama, M., Borges, M., Zhang, X., Parsons, D. W., Lin, J. C.-H., Palmisano, E., Brune, K., Jaffee, E. M., et al. (2009) · Science · doi:10.1126/science.1171202 · Cited by 826 · cited 2×
“Susceptibility genes that have been identified range from rare mutations in genes associated with cancer syndromes to common SNPs. Designs that include familybased and case-control studies have uncovered mutations in known syndrome-related genes, such as BRCA1, BRCA2, CDKN2A, and CFTR. Next-generation sequencing has i…”
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Obesity and cancer—mechanisms underlying tumour progression and recurrence
Park, J., Morley, T. S., Kim, M. G., Clegg, D. J., & Scherer, P. E. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.94 · Cited by 808

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Hu, D., Peng, F., Lin, X., Zhang, H., Xia, Y., Lin, J., Zheng, X., & Niu, W. (2019) · Journal of Cancer · doi:10.7150/jca.31184 · Cited by 4
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Authors: Andersen, D. K., Korc, M., Petersen, G. M., Eibl, G., Li, D., Rickels, M. R., Chari, S. T., & Abbruzzese, J. L.
Affiliations: National Institutes of Health (US)
Indiana University Indianapolis (US)
Mayo Clinic (US)
University of California, Los Angeles (US)
The University of Texas MD Anderson Cancer Center (US)
University of Pennsylvania (US)
Duke University (US)
Corresponding author: Abbruzzese, James L.
ORCID: Andersen, Dana K.
Korc, Murray
Petersen, Gloria M.
Eibl, Guido
Li, Donghui
Rickels, Michael R.
Chari, Suresh T.
Abbruzzese, James L.
Venue: Diabetes
Publisher: American Diabetes Association
Published: 2017-04-13
Volume: 66
Issue: 5
Pages: 1103-1110
ISSN: 0012-1797 (ISSN-L)
1939-327X
DOI: 10.2337/db16-1477
PMC: PMC5399609
OpenAlex: W2615250694
Cited by: 516
References: 50
Citations by year: 2026: 43 · 2025: 55 · 2024: 78 · 2023: 71 · 2022: 79 · 2021: 61 · 2020: 59 · 2019: 40 · 2018: 24 · 2017: 5
FWCI: 15.43
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.diabetesjournals.org/content/license (vor, 7 d)
Locations: Diabetes (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
eScholarship (California Digital Library) (submittedVersion)
IUScholarWorks (Indiana University) (submittedVersion)
Funders: National Institutes of Health
Topics: Health Sciences › Medicine › Oncology › Pancreatic and Hepatic Oncology Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
Keywords: pancreatic ductal adenocarcinoma, type 2 diabetes, pancreatic diabetes, new-onset diabetes, pancreatic cancer risk factors, diabetes management, early cancer detection
MeSH terms: Blood Glucose, Diabetes Mellitus, Diabetes Mellitus, Type 2, Humans, Hypoglycemic Agents, Inflammation, Obesity, Pancreatic Neoplasms, Risk Factors, Causality, Genetic Predisposition to Disease, Carcinoma, Pancreatic Ductal, Pancreatitis, Chronic

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