Role of Physical Activity for Weight Loss and Weight Maintenance

Cox, Carla E.

doi:10.2337/ds17-0013

Cited by 167Physical Activity and HealthObesity, Physical Activity, DietCardiovascular and exercise physiology

Role of Physical Activity for Weight Loss and Weight Maintenance

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Cox, Carla E.·2017·Diabetes Spectrum

DOI 10.2337/ds17-0013PMC PMC5556592

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Abstract

IN BRIEF This article reviews the impact of exercise on weight loss and weight maintenance and the possible reasons that weight loss outcomes resulting from exercise are not consistently realized.

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Crossref · 10.2337/ds17-0013

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In the presence of an altered hypothalamic set point in obesity, acute decreases in leptin theoretically lead to compensatory overeating and decreased metabolic rate, impairing weight loss.
“Acute decreases in leptin concentrations in response to acute bouts of aerobic and resistance exercise have been described [217] but, in the presence of an altered hypothalamic set point in obesity, theoretically lead to compensatory overeating and decreased metabolic rate, impairing weight loss [219,236,237].”
From The Role of Exercise in the Interplay between Myokines, Hepatokines, Osteokines, Adipokines, and Modulation of Inflammation for Energy Substrate Redistribution and Fat Mass Loss: A Review (2020) · cites this paper as [237]
The section “What Are Potential Explanations for Less Weight Loss Than Predicted From Exercise?” discusses compensatory food intake as a possible reason for limited weight loss and reports greater hunger and intake among nonresponders. It does not link this compensation to acute leptin decreases or an altered hypothalamic set point; the reported study found no significant change in resting metabolic rate. No page number is available in our copy. (LLM, conf=0.85)
Experimental — accuracy not yet measured
Behavioural programmes help to sustain new behaviours, relationships with foods and adherence to dietary advice.
“Behavioural programmes help to sustain new behaviours, relationships with foods and adherence to dietary advice [66–68].”
From Diets for weight management in adults with type 2 diabetes: an umbrella review of published meta-analyses and systematic review of trials of diets for diabetes remission (2022) · cites this paper as [67]
Current evidence regarding the effects of physical activity and exercise on weight loss is not strong.
“Furthermore, current evidence regarding the effects of physical activity and exercise on weight loss is not strong [41].”
From Feasibility, Usability, and Effectiveness of a Machine Learning–Based Physical Activity Chatbot: Quasi-Experimental Study (2021) · cites this paper as [41]

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Authors: Cox, C. E.
Affiliations: Providence Medical Group/Endocrinology, Diabetes and Nutrition, Missoula, MT
Corresponding author: Cox, Carla E.
ORCID: Cox, Carla E.
Venue: Diabetes Spectrum
Publisher: American Diabetes Association
Published: 2017-08-01
Volume: 30
Issue: 3
Pages: 157-160
ISSN: 1040-9165 (ISSN-L)
1944-7353
DOI: 10.2337/ds17-0013
PMC: PMC5556592
OpenAlex: W2747983289
Semantic Scholar: 8656d78b7b202c65a071739e0653762c68f48c56
Cited by: 167
References: 29
Citations by year: 2026: 17 · 2025: 20 · 2024: 41 · 2023: 29 · 2022: 22 · 2021: 16 · 2020: 15 · 2019: 4 · 2018: 1
FWCI: 4.01
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
creativecommons.org/licenses/by-nc-nd/3.0/ (vor, 1488 d)
Locations: Diabetes Spectrum (publishedVersion, cc-by-nc-nd)
Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
PubMed Central (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Physiology › Physical Activity and Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords: physical activity, weight loss, weight maintenance, obesity, weight loss outcomes

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Role of Physical Activity for Weight Loss and Weight Maintenance

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