Zinc in epidermis and dermis in healthy subjects
Open accessAbstract
Thin tangential skin biopsies were obtained from 40 healthy subjects by a shaving technique. The zinc content in these samples was determined by atomic absorption spectrophotometry. The mean concentration of zinc in epidermis was about 60 micrograms/g and in upper dermis 40 micrograms/g dry weight. The concentration was much higher in the upper than in the lower layer of dermis. There was no correlation between the tissue and serum concentration of zinc. Full awareness of the great risk for contamination is essential and special precautions are mandatory if reproducible results are to be obtained.
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The skin is the third most zinc-abundant tissue in the body, with greater amounts in the epidermis than in the dermis.
“The skin is the third most Zn-abundant tissue in the body, with greater amounts in the epidermis than in the dermis [99,102].”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [102]
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- Authors
- Michaëlsson, G., Ljunghall, K., & Danielson, B.
- Affiliations
- Uppsala University Hospital (SE)
- Venue
- Acta Dermato Venereologica
- Publisher
- Medical Journals Sweden AB
- Published
- 1980-07-07
- Volume
- 60
- Issue
- 4
- Pages
- 295-299
- ISSN
- 0001-5555 (ISSN-L)
- 1651-2057
- OpenAlex
- W2397978929
- Cited by
- 61
- References
- 3
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 5 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 2 · 2012: 3
- FWCI
- 0.46
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Acta Dermato Venereologica (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Keywords
- zinc, epidermis, dermis, serum zinc, healthy volunteers
- MeSH terms
- Adolescent, Adult, Contraceptives, Oral, Female, Humans, Male, Middle Aged, Skin, Spectrophotometry, Atomic, Zinc
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