NOX1 deficiency in apolipoprotein E-knockout mice is associated with elevated plasma lipids and enhanced atherosclerosis

Analyzing real-time PCR data by the comparative CT method

Schmittgen, T. D., & Livak, K. J. (2008) · Nature Protocols · doi:10.1038/nprot.2008.73 · Cited by 26,190 · see citing works

The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology

Bedard, K., & Krause, K.-H. (2007) · Physiological Reviews · doi:10.1152/physrev.00044.2005 · Cited by 6,989 · see citing works

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

Drummond, G. R., Selemidis, S., Griendling, K. K., & Sobey, C. G. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3403 · Cited by 899 · see citing works

Superoxide Production and Expression of Nox Family Proteins in Human Atherosclerosis

Sorescu, D., Weiss, D., Lassègue, B., Clempus, R. E., Szöcs, K., Sorescu, G. P., Valppu, L., Quinn, M. T., Lambeth, J. D., Vega, J. D., et al. (2002) · Circulation · doi:10.1161/01.cir.0000012917.74432.66 · Cited by 847 · see citing works

Effects of Angiotensin II Infusion on the Expression and Function of NAD(P)H Oxidase and Components of Nitric Oxide/cGMP Signaling

Mollnau, H., Wendt, M., Szöcs, K., Lassègue, B., Schulz, E., Oelze, M., Li, H., Bodenschatz, M., August, M., Kleschyov, A. L., et al. (2002) · Circulation Research · doi:10.1161/01.res.0000012569.55432.02 · Cited by 676 · see citing works

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis

Clarke, M. C. H., Figg, N. L., Maguire, J. J., Davenport, A. P., Goddard, M. J., Littlewood, T. D., & Bennett, M. R. (2006) · Nature Medicine · doi:10.1038/nm1459 · Cited by 645 · see citing works

p47phox is required for atherosclerotic lesion progression in ApoE–/– mice

Barry-Lane, P. A., Patterson, C., van der Merwe, M., Hu, Z., Holland, S. M., Yeh, E. T. H., & Runge, M. S. (2001) · Journal of Clinical Investigation · doi:10.1172/jci200111927 · Cited by 489 · see citing works

Nox1 Is Involved in Angiotensin II–Mediated Hypertension: A Study in Nox1-Deficient Mice

Matsuno, K., Yamada, H., Iwata, K., Jin, D., Katsuyama, M., Matsuki, M., Takai, S., Yamanishi, K., Miyazaki, M., Matsubara, H., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.573709 · Cited by 470 · see citing works

Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

Kleinschnitz, C., Grund, H., Wingler, K., Armitage, M. E., Jones, E., Mittal, M., Barit, D., Schwarz, T., Geis, C., Kraft, P., et al. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000479 · Cited by 447 · see citing works

Upregulation of Nox-Based NAD(P)H Oxidases in Restenosis After Carotid Injury

Szöcs, K., Lassegue, B. P., Sorescu, D., Hilenski, L. L., Valppu, L., Couse, T. L., Wilcox, J. N., Quinn, M. T., Lambeth, J. D., & Griendling, K. K. (2002) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/hq0102.102189 · Cited by 444 · see citing works

Nox1 Overexpression Potentiates Angiotensin II-Induced Hypertension and Vascular Smooth Muscle Hypertrophy in Transgenic Mice

Dikalova, A., Clempus, R., Lassègue, B., Cheng, G., McCoy, J., Dikalov, S., Martin, A. S., Lyle, A., Weber, D. S., Weiss, D., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.538934 · Cited by 438 · see citing works

Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration

Clarke, M. C. H., Littlewood, T. D., Figg, N., Maguire, J. J., Davenport, A. P., Goddard, M., & Bennett, M. R. (2008) · Circulation Research · doi:10.1161/circresaha.108.175976 · Cited by 396 · see citing works

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

Gray, S. P., Di Marco, E., Okabe, J., Szyndralewiez, C., Heitz, F., Montezano, A. C., de Haan, J. B., Koulis, C., El-Osta, A., Andrews, K. L., et al. (2013) · Circulation · doi:10.1161/circulationaha.112.132159 · Cited by 386 · see citing works

Role of NADPH Oxidase in the Vascular Hypertrophic and Oxidative Stress Response to Angiotensin II in Mice

Wang, H. D., Xu, S., Johns, D. G., Du, Y., Quinn, M. T., Cayatte, A. J., & Cohen, R. A. (2001) · Circulation Research · doi:10.1161/hh0901.089987 · Cited by 342 · see citing works

Decreased blood pressure in NOX1‐deficient mice

Gavazzi, G., Banfi, B., Deffert, C., Fiette, L., Schappi, M., Herrmann, F., & Krause, K.-H. (2006) · FEBS Letters · doi:10.1016/j.febslet.2005.12.049 · Cited by 321 · see citing works

Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE^−/−mice

Judkins, C. P., Diep, H., Broughton, B. R. S., Mast, A. E., Hooker, E. U., Miller, A. A., Selemidis, S., Dusting, G. J., Sobey, C. G., & Drummond, G. R. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00799.2009 · Cited by 299 · see citing works

gp91phox-Containing NADPH Oxidase Mediates Endothelial Dysfunction in Renovascular Hypertension

Jung, O., Schreiber, J. G., Geiger, H., Pedrazzini, T., Busse, R., & Brandes, R. P. (2004) · Circulation · doi:10.1161/01.cir.0000124223.00113.a4 · Cited by 255 · see citing works

NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition

Selemidis, S., Sobey, C. G., Wingler, K., Schmidt, H. H. H. W., & Drummond, G. R. (2008) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2008.08.005 · Cited by 241 · see citing works

The Nicotinamide Adenine Dinucleotide Phosphate Oxidase Homologues NOX1 and NOX2/gp91phox Mediate Hepatic Fibrosis in Mice

Paik, Y., Iwaisako, K., Seki, E., Inokuchi, S., Schnabl, B., Österreicher, C. H., Kisseleva, T., & Brenner, D. A. (2011) · Hepatology · doi:10.1002/hep.24281 · Cited by 195 · see citing works

[31] Quantification of matrix metalloproteinases in tissue samples

Woessner, J. F. (1995) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(95)48033-1 · Cited by 175 · see citing works

Atherosclerosis Is Attenuated by Limiting Superoxide Generation in Both Macrophages and Vessel Wall Cells

Vendrov, A. E., Hakim, Z. S., Madamanchi, N. R., Rojas, M., Madamanchi, C., & Runge, M. S. (2007) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.107.152629 · Cited by 173 · see citing works

Impaired Superoxide Production Due to a Deficiency in Phagocyte NADPH Oxidase Fails to Inhibit Atherosclerosis in Mice

Kirk, E. A., Dinauer, M. C., Rosen, H., Chait, A., Heinecke, J. W., & LeBoeuf, R. C. (2000) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.20.6.1529 · Cited by 171 · see citing works

Nox4 is a Novel Inducible Source of Reactive Oxygen Species in Monocytes and Macrophages and Mediates Oxidized Low Density Lipoprotein–Induced Macrophage Death

Lee, C. F., Qiao, M., Schröder, K., Zhao, Q. D., & Asmis, R. (2010) · Circulation Research · doi:10.1161/circresaha.109.215392 · Cited by 167 · see citing works

Mechanisms Contributing to Cerebral Infarct Size after Stroke: Gender, Reperfusion, T Lymphocytes, and Nox2-Derived Superoxide

Brait, V. H., Jackman, K. A., Walduck, A. K., Selemidis, S., Diep, H., Mast, A., Guida, E., Broughton, B. R. S., Drummond, G. R., & Sobey, C. G. (2010) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2010.14 · Cited by 155 · see citing works

Role for Nox1 NADPH oxidase in atherosclerosis

Sheehan, A. L., Carrell, S., Johnson, B., Stanić, B., Bánfi, B., & Miller, F. J. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.02.028 · Cited by 148 · see citing works

NAD(P)H Oxidases in Rat Basilar Arterial Endothelial Cells

Ago, T., Kitazono, T., Kuroda, J., Kumai, Y., Kamouchi, M., Ooboshi, H., Wakisaka, M., Kawahara, T., Rokutan, K., Ibayashi, S., et al. (2005) · Stroke · doi:10.1161/01.str.0000163111.05825.0b · Cited by 135 · see citing works

The p47phox- and NADPH oxidase organiser 1 (NOXO1)-dependent activation of NADPH oxidase 1 (NOX1) mediates endothelial nitric oxide synthase (eNOS) uncoupling and endothelial dysfunction in a streptozotocin-induced murine model of diabetes

Youn, J. Y., Gao, L., & Cai, H. (2012) · Diabetologia · doi:10.1007/s00125-012-2557-6 · Cited by 128 · see citing works

Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4

Wendt, M. C., Daiber, A., Kleschyov, A. L., Mülsch, A., Sydow, K., Schulz, E., Chen, K., Keaney, J. F., Lassègue, B., Walter, U., et al. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.03.020 · Cited by 122 · see citing works

Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2‐deficient mice

Jackman, K. A., Miller, A. A., Silva, T. M. D., Crack, P. J., Drummond, G. R., & Sobey, C. G. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2008.00073.x · Cited by 120 · see citing works

Nox Activator 1

Niu, X.-L., Madamanchi, N. R., Vendrov, A. E., Tchivilev, I., Rojas, M., Madamanchi, C., Brandes, R. P., Krause, K. H., Humphries, J., Smith, A., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.908319 · Cited by 115 · see citing works

NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation

Cui, W., Matsuno, K., Iwata, K., Ibi, M., Matsumoto, M., Zhang, J., Zhu, K., Katsuyama, M., Torok, N. J., & Yabe‐Nishimura, C. (2011) · Hepatology · doi:10.1002/hep.24465 · Cited by 113 · see citing works

An Osteopontin–NADPH Oxidase Signaling Cascade Promotes Pro–Matrix Metalloproteinase 9 Activation in Aortic Mesenchymal Cells

Lai, C., Seshadri, V., Huang, K., et al. (2006) · Circulation Research · doi:10.1161/01.res.0000227550.00426.60 · Cited by 112 · see citing works

Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18

Valente, A. J., Yoshida, T., Murthy, S. N., Sakamuri, S. S. V. P., Katsuyama, M., Clark, R. A., Delafontaine, P., & Chandrasekar, B. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00231.2012 · Cited by 103 · see citing works

NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice

Kahles, T., Kohnen, A., Heumueller, S., Rappert, A., Bechmann, I., Liebner, S., Wittko, I. M., Neumann-Haefelin, T., Steinmetz, H., Schroeder, K., et al. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.05.023 · Cited by 91 · see citing works

Noxa1 is a central component of the smooth muscle NADPH oxidase in mice

Ambasta, R. K., Schreiber, J. G., Janiszewski, M., Busse, R., & Brandes, R. P. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.12.035 · Cited by 90 · see citing works

Nox1 transactivation of epidermal growth factor receptor promotes N-cadherin shedding and smooth muscle cell migration

Jagadeesha, D. K., Takapoo, M., Bánfi, B., Bhalla, R. C., & Miller, F. J. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvr308 · Cited by 80 · see citing works

Augmented Superoxide Production By Nox2-Containing NADPH Oxidase Causes Cerebral Artery Dysfunction During Hypercholesterolemia

Miller, A. A., Silva, T. M. D., Judkins, C. P., Diep, H., Drummond, G. R., & Sobey, C. G. (2010) · Stroke · doi:10.1161/strokeaha.109.575365 · Cited by 74 · see citing works

Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke

Jackman, K. A., Miller, A. A., Drummond, G. R., & Sobey, C. G. (2009) · Brain Research · doi:10.1016/j.brainres.2009.06.056 · Cited by 72 · see citing works

Upregulation of Vascular NAD(P)H Oxidase Subunit gp91phox and Impairment of the Nitric Oxide Signal Transduction Pathway in Hypertension

Morawietz, H., Weber, M., Rueckschloss, U., Lauer, N., Hacker, A., & Kojda, G. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5312 · Cited by 69 · see citing works

Nox4 NADPH oxidase contributes to smooth muscle cell phenotypes associated with unstable atherosclerotic plaques

Xu, S., Chamseddine, A. H., Carrell, S., & Miller, F. J. (2014) · Redox Biology · doi:10.1016/j.redox.2014.04.004 · Cited by 66 · see citing works

Inhibitory Effect of Delphinidin on Monocyte–Endothelial Cell Adhesion Induced by Oxidized Low-Density Lipoprotein via ROS/p38MAPK/NF-κB Pathway

Chen, C.-Y., Yi, L., Jin, X., Zhang, T., Fu, Y.-J., Zhu, J.-D., Mi, M.-T., Zhang, Q.-Y., Ling, W.-H., & Yu, B. (2011) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-011-9216-2 · Cited by 61 · see citing works

Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation

Bruder-Nascimento, T. B., Chinnasamy, P., Riascos‐Bernal, D. F., Cáu, S. B. D. A., Callera, G. E., Touyz, R. M., Tostes, R. C., & Sibinga, N. E. S. (2013) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2013.10.013 · Cited by 58 · see citing works

Activation of NADPH Oxidase 1 Increases Intracellular Calcium and Migration of Smooth Muscle Cells

Zimmerman, M. C., Takapoo, M., Jagadeesha, D. K., Stanić, B., Bánfi, B., Bhalla, R. C., & Miller, F. J. (2011) · Hypertension · doi:10.1161/hypertensionaha.111.177006 · Cited by 54 · see citing works

Involvement of NADPH oxidase in oxidized LDL-induced upregulation of heat shock factor-1 and plasminogen activator inhibitor-1 in vascular endothelial cells

Zhao, R., Ma, X., Xie, X., & Shen, G. X. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.91023.2008 · Cited by 51 · see citing works

Increased Epidermal Growth Factor–Like Ligands Are Associated With Elevated Vascular Nicotinamide Adenine Dinucleotide Phosphate Oxidase in a Primate Model of Atherosclerosis

Stanić, B., Pandey, D., Fulton, D. J., & Miller, F. J. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.256107 · Cited by 49 · see citing works

Tyrphostin AG490 reduces NAPDH oxidase activity and expression in the aorta of hypercholesterolemic apolipoprotein E-deficient mice

Fenyo, I. M., Albulescu, I. C., Raicu, M., & Manea, A. (2011) · Vascular Pharmacology · doi:10.1016/j.vph.2011.03.006 · Cited by 40 · see citing works

Increased Expression of Nox1 in Neointimal Smooth Muscle Cells Promotes Activation of Matrix Metalloproteinase-9

Xu, S., Shriver, A. S., Jagadeesha, D. K., Chamseddine, A. H., Szöcs, K., Weintraub, N. L., Griendling, K. K., Bhalla, R. C., & Miller, F. J. (2012) · Journal of Vascular Research · doi:10.1159/000332958 · Cited by 39 · see citing works

Nox1 NADPH oxidase is necessary for late but not early myocardial ischaemic preconditioning

Jiang, S., Streeter, J., Schickling, B., Zimmerman, K., Weiss, R. M., & Miller, F. J. (2014) · Cardiovascular Research · doi:10.1093/cvr/cvu027 · Cited by 24 · see citing works

Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression

Kim, H. A., Brait, V. H., Lee, S., Silva, T. M. D., Diep, H., Eisenhardt, A., Drummond, G. R., & Sobey, C. G. (2012) · Brain Research · doi:10.1016/j.brainres.2012.09.023 · Cited by 23 · see citing works

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

Forrester, S. J., Kikuchi, D. S., Hernandes, M. S., Xu, Q., & Griendling, K. K. (2018) · Circulation Research · doi:10.1161/circresaha.117.311401 · Cited by 2,081 · see citing works

Roles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis

Förstermann, U., Xia, N., & Li, H. (2017) · Circulation Research · doi:10.1161/circresaha.116.309326 · Cited by 1,519 · see citing works

Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

Tejero, J., Shiva, S., & Gladwin, M. T. (2019) · Physiological Reviews · doi:10.1152/physrev.00036.2017 · Cited by 541 · see citing works

Therapeutic potential of nadph oxidase 1/4 inhibitors

Teixeira, G., Szyndralewiez, C., Molango, S., Carnesecchi, S., Heitz, F., Wiesel, P., & Wood, J. M. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13532 · Cited by 163 · see citing works

NADPH Oxidases and Mitochondria in Vascular Senescence

Salazar, G. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19051327 · Cited by 133 · see citing works

The Nox Family of NADPH Oxidases: Friend or Foe of the Vascular System?

Takac, I., Schröder, K., & Brandes, R. P. (2011) · Current Hypertension Reports · doi:10.1007/s11906-011-0238-3 · Cited by 142 · see citing works

Role of NADPH Oxidase in the Endothelial Dysfunction and Oxidative Stress in Aorta of Aged Spontaneous Hypertensive Rats

Taye, A., & Wind, S. (2010) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 4 · see citing works

Nox1-Based NADPH Oxidase Is the Major Source of UVA-Induced Reactive Oxygen Species in Human Keratinocytes

Valencia, A., & Kochevar, I. E. (2008) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700960 · Cited by 194 · see citing works

NOX1/NADPH in the hypothalamus regulate anxiety-like behaviors in mice

Ibi, M., Zhang, X., & Yabe‐Nishimura, C. (2020) · Proceedings for Annual Meeting of The Japanese Pharmacological Society · doi:10.1254/jpssuppl.93.0_1-lbs-07

Novel Nox homologues in the vasculature: focusing on Nox4 and Nox5

Montezano, A. C. I., Burger, D. E., Ceravolo, G. S., Yusuf, H., Montero, M. J., & Touyz, R. M. (2010) · Clinical Science · doi:10.1042/cs20100384 · Cited by 106 · see citing works