The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Assessment of multifunctional activity of bioactive peptides derived from fermented milk by specific Lactobacillus plantarum strains
Open accessAbstract
Milk-derived bioactive peptides with a single activity (e.g., antioxidant, immunomodulatory, or antimicrobial) have been previously well documented; however, few studies describe multifunctional bioactive peptides, which may be preferred over single-activity peptides, as they can simultaneously trigger, modulate, or inhibit multiple physiological pathways. Hence, the aim of this study was to assess the anti-inflammatory, antihemolytic, antioxidant, antimutagenic, and antimicrobial activities of crude extracts (CE) and peptide fractions (<3 and 3-10 kDa) obtained from fermented milks with specific Lactobacillus plantarum strains. Overall, CE showed higher activity than both peptide fractions (<3 and 3-10 kDa) in most of the activities assessed. Furthermore, activity of <3 kDa was generally higher, or at least equal, to the 3 to 10 kDa peptide fractions. In particular, L. plantarum 55 crude extract or their fractions showed the higher anti-inflammatory (723.68-1,759.43μg/mL of diclofenac sodium equivalents), antihemolytic (36.65-74.45% of inhibition), and antioxidant activity [282.8-362.3µmol of Trolox (Sigma-Aldrich, St. Louis, MO) equivalents]. These results provide valuable evidence of multifunctional role of peptides derived of fermented milk by the action of specific L. plantarum strains. Thus, they may be considered for the development of biotechnological products to be used to reduce the risk of disease or to enhance a certain physiological function.
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Cites
Antioxidant activity applying an improved ABTS radical cation decolorization assay
Re, R., Pellegrini, N., Proteggente, A., Pannala, A., Yang, M., & Rice-Evans, C. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00315-3 · Cited by 26,165
Antimicrobial peptides of multicellular organisms
Zasloff, M. (2002) · Nature · doi:10.1038/415389a · Cited by 8,457
Prior, R. L., Wu, X., & Schaich, K. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0502698 · Cited by 5,650
Ou, B., Hampsch-Woodill, M., & Prior, R. L. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf010586o · Cited by 2,932
The Ames Salmonella/microsome mutagenicity assay
Mortelmans, K., & Zeiger, E. (2000) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/s0027-5107(00)00064-6 · Cited by 2,098
Review on in vivo and in vitro methods evaluation of antioxidant activity
Alam, M. N., Bristi, N. J., & Rafiquzzaman, M. (2013) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2012.05.002 · Cited by 1,758
Food-derived peptides with biological activity: from research to food applications.
Hartmann, R., & Meisel, H. (2007) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2007.01.013 · Cited by 1,102
Antimicrobial peptides: premises and promises
Reddy, K. V. R., Yedery, R. D., & Aranha, C. (2004) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2004.09.005 · Cited by 1,068
Milk-derived bioactive peptides: From science to applications
Korhonen, H. (2009) · Journal of Functional Foods · doi:10.1016/j.jff.2009.01.007 · Cited by 700
Seppo, L., Jauhiainen, T., Poussa, T., & Korpela, R. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.2.326 · Cited by 666
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Health benefits of fermented foods
Şanlier, N., Gökcen, B. B., & Sezgin, A. C. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1383355 · Cited by 789
Sánchez, A., & Vázquez, A. (2017) · Food Quality and Safety · doi:10.1093/fqs/fyx006 · Cited by 868
Food-Derived Bioactive Peptides in Human Health: Challenges and Opportunities
Chakrabarti, S., Guha, S., & Majumder, K. (2018) · Nutrients · doi:10.3390/nu10111738 · Cited by 699
Bioactive peptides as natural antioxidants in food products – A review
Lorenzo, J. M., Munekata, P. E. S., Gómez, B., Barba, F. J., Mora, L., Pérez-Santaescolástica, C., & Toldrá, F. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.07.003 · Cited by 502
Novel technologies for the production of bioactive peptides
Ulug, S. K., Jahandideh, F., & Wu, J. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.12.002 · Cited by 386
Metadata
- Authors
- Aguilar-Toalá, J. E., Santiago-López, L., Peres, C. M., Peres, C., Garcia, H. S., Vallejo-Cordoba, B., González-Córdova, A. F., & Hernández-Mendoza, A.
- Venue
- Journal of Dairy Science
- Publisher
- American Dairy Science Association
- Published
- 2017-01
- Volume
- 100
- Issue
- 1
- Pages
- 65-75
- ISSN
- 0022-0302 (ISSN-L)
- OpenAlex
- W2552606627
- Cited by
- 256
- References
- 64
- FWCI
- 7.37
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Aguilar-Toalá, J. E., Santiago-López, L., Peres, C. M., Peres, C., Garcia, H. S., Vallejo-Cordoba, B., González-Córdova, A. F., & Hernández-Mendoza, A. (2017). Assessment of multifunctional activity of bioactive peptides derived from fermented milk by specific Lactobacillus plantarum strains. Journal of Dairy Science. https://doi.org/10.3168/jds.2016-11846
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