The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Characterization of complications associated with open and endoscopic craniosynostosis surgery at a single institution
Open accessAbstract
OBJECT: The authors present a retrospective cohort study examining complications in patients undergoing surgery for craniosynostosis using both minimally invasive endoscopic and open approaches. METHODS: Over the past 10 years, 295 nonsyndromic patients (140 undergoing endoscopic procedures and 155 undergoing open procedures) and 33 syndromic patients (endoscopic procedures in 10 and open procedures in 23) met the authors’ criteria. Variables analyzed included age at surgery, presence of a preexisting CSF shunt, skin incision method, estimated blood loss, transfusions of packed red blood cells, use of intravenous steroids or tranexamic acid, intraoperative durotomies, procedure length, and length of hospital stay. Complications were classified as either surgically or medically related. RESULTS: In the nonsyndromic endoscopic group, the authors experienced 3 (2.1%) surgical and 5 (3.6%) medical complications. In the nonsyndromic open group, there were 2 (1.3%) surgical and 7 (4.5%) medical complications. Intraoperative durotomies occurred in 5 (3.6%) endoscopic and 12 (7.8%) open cases, were repaired primarily, and did not result in reoperations for CSF leakage. Similar complication rates were seen in syndromic cases. There was no death or permanent morbidity. Additionally, endoscopic procedures were associated with significantly decreased estimated blood loss, transfusions, procedure length, and length of hospital stay compared with open procedures. CONCLUSIONS: Rates of intraoperative durotomies and surgical and medical complications were comparable between endoscopic and open techniques. This is the largest direct comparison to date between endoscopic and open interventions for synostosis, and the results are in agreement with previous series that endoscopic surgery confers distinct advantages over open surgery in appropriate patient populations.
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“Endoscopic surgery demonstrates a significantly lower mortality rate compared to open techniques, attributed to its minimally invasive nature and reduced surgical trauma.”
From Developments in diagnostic and surgical techniques in children with sagittal suture craniosynostosis: a systematic review spanning the last 30 years (2025) · cites this paper as [12]
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“Endoscopic procedures are particularly advantageous when performed early in life, as they involve smaller incisions and facilitate quicker recovery [12–15].”
From Developments in diagnostic and surgical techniques in children with sagittal suture craniosynostosis: a systematic review spanning the last 30 years (2025) · cites this paper as [12]
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“However, it should be noted at this point that due to the advanced age of open surgical approaches and the more complex findings, potentially more difficult extensive operations must be performed compared to younger children who may be operated on with less pronounced findings [12].”
From Developments in diagnostic and surgical techniques in children with sagittal suture craniosynostosis: a systematic review spanning the last 30 years (2025) · cites this paper as [12]
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Metadata
- Authors
- Han, R. H., Nguyen, D. C., Bruck, B. S., Skolnick, G. B., Yarbrough, C. K., Naidoo, S. D., Patel, K. B., Kane, A. A., Woo, A. S., & Smyth, M. D.
- Affiliations
- Department of Neurological Surgery and
- Washington University in St. Louis (US)
- The University of Texas Southwestern Medical Center (US)
- ORCID
- Venue
- Journal of Neurosurgery: Pediatrics
- Published
- 2016-03
- Volume
- 17
- Issue
- 3
- Pages
- 361-370
- ISSN
- 1933-0707 (ISSN-L)
- 1933-0715
- PMC
- PMC4775423
- OpenAlex
- W2181195897
- Cited by
- 123
- References
- 35
- Citations by year
- 2026: 7 · 2025: 19 · 2024: 15 · 2023: 13 · 2022: 15 · 2021: 10 · 2020: 15 · 2019: 9 · 2018: 10 · 2017: 8 · 2016: 2
- FWCI
- 4.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Neurosurgery Pediatrics (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (UL1TR000448, TL1TR000449)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Surgery › Craniofacial Disorders and Treatments
- Health Sciences › Medicine › Clinical Neurology › Neurosurgical Procedures and Complications
- Health Sciences › Medicine › Surgery › Pectus Deformity Diagnosis and Treatment
- Keywords
- craniosynostosis, endoscopic craniosynostosis surgery, surgical complications, syndromic craniosynostosis, nonsyndromic craniosynostosis, blood loss, blood transfusion, length of hospital stay, cerebrospinal fluid shunt
- MeSH terms
- Child, Child, Preschool, Craniosynostoses, Humans, Infant, Infant, Newborn, Missouri, Postoperative Complications, Reoperation, Retrospective Studies, Treatment Outcome, Minimally Invasive Surgical Procedures, Plastic Surgery Procedures
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