Blastomycosis mortality rates, United States, 1990–2010
Open accessAbstract
Blastomycosis is a potentially fatal fungal infection endemic to parts of North America. We used national multiple-cause-of-death data and census population estimates for 1990-2010 to calculate age-adjusted mortality rates and rate ratios (RRs). We modeled trends over time using Poisson regression. Death occurred more often among older persons (RR 2.11, 95% confidence limit [CL] 1.76, 2.53 for those 75-84 years of age vs. 55-64 years), men (RR 2.43, 95% CL 2.19, 2.70), Native Americans (RR 4.13, 95% CL 3.86, 4.42 vs. whites), and blacks (RR 1.86, 95% CL 1.73, 2.01 vs. whites), in notably younger persons of Asian origin (mean = 41.6 years vs. 64.2 years for whites); and in the South (RR 18.15, 95% CL 11.63, 28.34 vs. West) and Midwest (RR 23.10, 95% CL14.78, 36.12 vs. West). In regions where blastomycosis is endemic, we recommend that the diagnosis be considered in patients with pulmonary disease and that it be a reportable disease.
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The increased risk for hospitalization among racial and ethnic minorities may signify blastomycosis-related health disparities.
“The increased risk for hospitalization among racial and ethnic minorities may signify blastomycosis-related health disparities [178–180].”
From Race and ethnicity: Risk factors for fungal infections? (2023) · cites this paper as [179]
The increased risk for hospitalization among persons of nonwhite races lends further evidence to the existence of blastomycosis-related health disparities.
“The increased risk for hospitalization among persons of nonwhite races lends further evidence to the existence of blastomycosis-related health disparities, as previously suspected (15–17).”
From Blastomycosis Surveillance in 5 States, United States, 1987–2018 (2021) · cites this paper as [15]
Another study found a decline in blastomycosis-associated deaths nationwide during 1990-2010.
“Another study found a decline in blastomycosis-associated deaths nationwide during 1990–2010 (15); the reasons for the increase in deaths we observed during 2007–2017 are unclear but could reflect improvements in case follow-up, a decline in reporting of less severe cases, or other surveillance changes over time.”
From Blastomycosis Surveillance in 5 States, United States, 1987–2018 (2021) · cites this paper as [15]
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- Authors
- Khuu, D., Shafir, S., Bristow, B., & Sorvillo, F.
- Affiliations
- University of California, Los Angeles (US)
- Corresponding author
- Khuu, Diana
- ORCID
- Khuu, Diana
- Venue
- Emerging Infectious Diseases
- Published
- 2014-11
- Volume
- 20
- Issue
- 11
- Pages
- 1789-1794
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- PMC
- PMC4214285
- OpenAlex
- W2054122662
- Cited by
- 47
- References
- 26
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 2 · 2023: 5 · 2022: 3 · 2021: 9 · 2020: 9 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 3 · 2015: 6
- FWCI
- 2.52
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Emerging infectious diseases (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- University of California, Los Angeles
- Topics
- Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Microbiology › Actinomycetales infections and treatment
- Keywords
- blastomycosis, mortality rates, age-adjusted mortality, regional variation in mortality, racial and ethnic disparities, sex differences, older adults, Native Americans, Asian Americans, endemic fungal infection, lung disease, notifiable diseases, mortality trends
- MeSH terms
- Age Factors, Blastomycosis, Cause of Death, Ethnicity, Humans, Sex Factors, United States, History, 20th Century, History, 21st Century, Datasets as Topic
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