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Cited by 542

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States

Open access
Harcourt, Jennifer, Tamin, Azaibi, Lu, Xiaoyan, Kamili, Shifaq, Sakthivel, Senthil K., Murray, Janna, Queen, Krista, Tao, Ying, Paden, Clinton R., Zhang, Jing, Li, Yan, Uehara, Anna, Wang, Haibin, Goldsmith, Cynthia, Bullock, Hannah A., Wang, Lijuan, Whitaker, Brett, Lynch, Brian, Gautam, Rashi, Schindewolf, Craig, Lokugamage, Kumari G., Scharton, Dionna, Plante, Jessica A., Mirchandani, Divya, Widen, Steven G., Narayanan, Krishna, Makino, Shinji, Ksiazek, Thomas G., Plante, Kenneth S., Weaver, Scott C., Lindstrom, Stephen, Tong, Suxiang, Menachery, Vineet D., Thornburg, Natalie J.·2020·Emerging Infectious Diseases

Abstract

A novel coronavirus, severe acute respiratory syn- drome coronavirus 2 (SARS-CoV-2), has been identified as the source of a pneumonia outbreak in Wuhan, China, in late 2019 (1,2).The virus was found to be a member of the β coronavirus family, in the same species as SARS-CoV and SARS-related bat CoVs (3,4).Patterns of spread indicate that SARS-CoV-2 can be transmitted person-to-person, and may be more transmissible than SARS-CoV (5-7).The spike protein of coronaviruses mediates virus binding and cell entry.Initial characterization of SARS-CoV-2 spike indicates that it binds the same receptor as SARS-CoV angiotensin-converting enzyme, which is expressed in both upper and lower human respiratory tracts (8).The unprecedented rapidity of spread of this outbreak represents a critical need for reference reagents.The public health community requires viral lysates to serve as diagnostic references, and the research community needs virus isolates to test antiviral compounds, develop new vaccines, and perform basic research.In this article, we describe isolation of SARS-CoV-2 from a patient who had coronavirus disease (COVID-19) in the United States and described its genomic sequence and replication characteristics.We have made the virus isolate available to the public health community by depositing it into 2 virus reagent repositories.

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Metadata

Authors
Harcourt, J., Tamin, A., Lu, X., Kamili, S., Sakthivel, S. K., Murray, J., Queen, K., Tao, Y., Paden, C. R., Zhang, J., Li, Y., Uehara, A., Wang, H., Goldsmith, C., Bullock, H. A., Wang, L., Whitaker, B., Lynch, B., Gautam, R., Schindewolf, C., Lokugamage, K. G., Scharton, D., Plante, J. A., Mirchandani, D., Widen, S. G., Narayanan, K., Makino, S., Ksiazek, T. G., Plante, K. S., Weaver, S. C., Lindstrom, S., Tong, S., Menachery, V. D., & Thornburg, N. J.
Venue
Emerging Infectious Diseases
Published
2020-06
Volume
26
Issue
6
Pages
1266-1273
ISSN
  • 1080-6040 (ISSN-L)
  • 1080-6059
OpenAlex
W3009584253
Cited by
542
References
8
FWCI
14.18
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States. https://app.cochat.ai/papers/10.3201/eid2606.200516
The paper
Harcourt, J., Tamin, A., Lu, X., Kamili, S., Sakthivel, S. K., Murray, J., Queen, K., Tao, Y., Paden, C. R., Zhang, J., Li, Y., Uehara, A., Wang, H., Goldsmith, C., Bullock, H. A., Wang, L., Whitaker, B., Lynch, B., Gautam, R., . . . Thornburg, N. J. (2020). Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States. Emerging Infectious Diseases. https://doi.org/10.3201/eid2606.200516

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.