Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

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2. Greek Sage Exhibits Neuroprotective Activity against Amyloid Beta‐Induced Toxicity
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3. Analyzing Olfactory Neuron Precursors Non-Invasively Isolated through NADH FLIM as a Potential Tool to Study Oxidative Stress in Alzheimer’s Disease
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4. PI3K/AKT/Nrf2 signalling pathway is involved in the ameliorative effects of xanthohumol on amyloid β-induced oxidative damage and bone loss
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5. Physical exercise-mediated neuroprotective mechanisms in Parkinson's disease, Alzheimer's disease, and epilepsy
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6. Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice
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7. Tau association with synaptic mitochondria coincides with energetic dysfunction and excitatory synapse loss in the P301S tauopathy mouse model
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8. Reactive Oxygen Species as a Common Pathological Link Between Alcohol Use Disorder and Alzheimer’s Disease with Therapeutic Implications
   Hyein Song, Jiyong Lee, Yeeun Lee, Seungju Kim, Shinwoo Kang · 2025 · International Journal of Molecular Sciences
9. B Lymphocytes in Alzheimer’s Disease—A Comprehensive Review
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10. Sideritis scardica Extracts Demonstrate Neuroprotective Activity against Aβ25–35 Toxicity
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12. Plasma and cerebrospinal fluid nonenzymatic protein damage is sustained in Alzheimer's disease
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13. The old second messenger cAMP teams up with novel cell death mechanisms: potential translational therapeutical benefit for Alzheimer’s disease and Parkinson’s disease
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14. Modulation of Mitochondrial Function as a Therapeutic Strategy for Neurodegenerative Diseases
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15. Molecular Identification and Phytochemical Analysis and Bioactivity Assessment of Catharanthus roseus Leaf Extract: Exploring Antioxidant Potential and Antimicrobial Activities
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16. Design, Synthesis, and Biological Evaluation of Ferulic Acid Template-Based Novel Multifunctional Ligands Targeting NLRP3 Inflammasome for the Management of Alzheimer’s Disease
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17. Common cytokine receptor gamma chain family cytokines activate MAPK, PI3K, and JAK/STAT pathways in microglia to influence Alzheimer’s Disease
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18. Alzheimer’s Disease, Obesity, and Type 2 Diabetes: Focus on Common Neuroglial Dysfunctions (Critical Review and New Data on Human Brain and Models)
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19. Peptide-based inhibitors and nanoparticles: Emerging therapeutics for Alzheimer’s disease
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20. A Snapshot on the Current Status of Alzheimer’s Disease, Treatment Perspectives, in-Vitro and in-Vivo Research Studies and Future Opportunities
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21. Nanomedicines for Subcellular Targeting: The Mitochondrial Perspective
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22. Myocardial Infarction Predisposes Neurodegenerative Diseases
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23. Utility of Reactive Species Generation in Plasma Medicine for Neuronal Development
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24. Engineered nanoparticle-induced epigenetic changes: An important consideration in nanomedicine
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25. Grape seed extract effects on hippocampal neurogenesis, synaptogenesis and dark neurons production in old mice. Can this extract improve learning and memory in aged animals?
    Seyed Hamidreza Rastegar-Moghaddam, Maryam Bigham, Mahmoud Hosseini, Alireza Ebrahimzadeh‐Bideskan, Amir Mohammad Malvandi, Abbas Mohammadipour · 2021 · Nutritional Neuroscience
26. Synthesis and In Vitro Antioxidant Activity of New Pyrimidin/Benzothiazol-Substituted Piperazinyl Flavones
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27. Platelet Extracellular Vesicles as Natural Delivery Vehicles for Mitochondrial Dysfunction Therapy?
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28. Ambroxol confers neuroprotection against scopolamine-induced Alzheimer’s-like pathology by modulating oxidative stress, neuroinflammation, and cognitive deficits via Nrf-2/JNK/GSK-3β signaling pathways
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29. Copper, Cuproptosis, and Neurodegenerative Diseases
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30. Targeting macrophage-derived SPP1 enhances CD8 T cell infiltration via ROS-DNA fragment/cGAS-STING/STAT1-mediated CXCL9/10 in tumor microenvironment
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31. TO901317 activation of LXR-dependent pathways mitigate amyloid-beta peptide-induced neurotoxicity in 3D human neural stem cell culture scaffolds and AD mice
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32. Pinus halepensis Essential Oil Ameliorates Aβ1-42-Induced Brain Injury by Diminishing Anxiety, Oxidative Stress, and Neuroinflammation in Rats
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33. Association between the triglyceride-glucose index and cognitive impairment in China: a community population-based cross-sectional study
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34. Oxazole-4-carboxamide/butylated hydroxytoluene hybrids with GSK-3β inhibitory and neuroprotective activities against Alzheimer's disease
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35. Folicitin abrogates scopolamine induced hyperlipidemia and oxidative stress mediated neuronal synapse and memory dysfunction in mice
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36. Transcriptome analysis identifies the role of Class I histone deacetylase in Alzheimer’s disease
    Fan Geng, Na Zhao, Chen Xiu, Xue-Ting Liu, Mengmeng Zhu, Ying Jiang, Qingguo Ren · 2023 · Heliyon
37. Hydrocortisone Mitigates Alzheimer’s-Related Cognitive Decline through Modulating Oxidative Stress and Neuroinflammation
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38. Effects of Redox Homeostasis and Mitochondrial Damage on Alzheimer’s Disease
    Yi‐Hsuan Wu, Hsi‐Lung Hsieh · 2023 · Antioxidants
39. Oxidative stress is associated with Aβ accumulation in chronic sleep deprivation model
    Zhao Beiyu, Rong Zhou, Yi Zhao, Shan Wei, Liu Peng, Wei Meng, Wei Peng, Ye Yuan, Qiumin Qu · 2024 · Brain Research
40. Neuroprotective, Anti-Inflammatory and Antifibrillogenic Offerings by Emodin against Alzheimer’s Dementia: A Systematic Review
    Priyanka Saha, Faraz Ahmad · 2024 · ACS Omega
41. Withania somnifera (Ashwagandha) Improves Spatial Memory, Anxiety and Depressive-like Behavior in the 5xFAD Mouse Model of Alzheimer’s Disease
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42. Ginsenoside Re Regulates Oxidative Stress through the PI3K/Akt/Nrf2 Signaling Pathway in Mice with Scopolamine-Induced Memory Impairments
    Xin Li, Kai Zheng, Hao Chen, Wei Li · 2024 · Current Issues in Molecular Biology
43. Multicomponent reactions driving the discovery and optimization of agents targeting central nervous system pathologies
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44. Tiaoxin Recipe, a Chinese herbal formula, inhibits microRNA-34a expression in the APPswe/PS1ΔE9 mouse model of Alzheimer’s disease
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45. Intranasal insulin treatment modulates the neurotropic, inflammatory, and oxidant mechanisms in the cortex and hippocampus in a low-grade inflammation model
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46. Activation of Apoptosis in a βB1-CTGF Transgenic Mouse Model
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47. Acute exposition to Roundup Transorb® induces systemic oxidative stress and alterations in the expression of newly sequenced genes in silverside fish (Odontesthes humensis)
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48. Blood-based biomarkers of agitation in Alzheimer's disease: Advances and future prospects
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49. The impact of gamma-radiation on the cerebral- and cerebellar- cortex of male rats’ brain
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50. Age-related Mitochondrial Dysfunction in Parkinson's Disease: New Insights Into the Disease Pathology
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51. Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice
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52. Effect of antioxidant intake patterns on risks of dementia and cognitive decline
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53. AI-assisted multi-OMICS analysis reveals new markers for the prediction of AD
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54. Fluvastatin protects neuronal cells from hydrogen peroxide-induced toxicity with decreasing oxidative damage and increasing PI3K/Akt/mTOR signalling
    Miaoxia Wang, Jia Wang, Meirong Liu, Gang Chen · 2021 · Journal of Pharmacy and Pharmacology
55. Association Study of Alcohol Dehydrogenase and Aldehyde Dehydrogenase Polymorphism With Alzheimer Disease in the Taiwanese Population
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56. Design, synthesis and in-vitro evaluation of fluorinated triazoles as multi-target directed ligands for Alzheimer disease
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57. The hibernation-derived compound SUL-138 shifts the mitochondrial proteome towards fatty acid metabolism and prevents cognitive decline and amyloid plaque formation in an Alzheimer’s disease mouse model
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58. Fucosyltransferase 8 (FUT8) and core fucose expression in oxidative stress response
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59. CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer’s Disease
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60. Design, Synthesis, and Biological Activity of Donepezil: Aromatic Amine Hybrids as Anti-Alzheimerss Drugs
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61. Bioassay-guided identification of potential Alzheimer’s disease therapeutic agents from Kaempferol-Enriched fraction of Aframomum melegueta seeds using in vitro and chemoinformatics approaches
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62. American Ginseng for the Treatment of Alzheimer’s Disease: A Review
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63. Move Your Body toward Healthy Aging: Potential Neuroprotective Mechanisms of Irisin in Alzheimer’s Disease
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64. Neuroprotection of phytic acid in Parkinson’s and Alzheimer’s disease
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65. Effect of berberine on cognitive function and β-amyloid precursor protein in Alzheimer’s disease models: a systematic review and meta-analysis
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66. Design, Synthesis, and Biological Evaluation of Ferulic Acid-Piperazine Derivatives Targeting Pathological Hallmarks of Alzheimer’s Disease
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67. Redox Oxygen Species‐Responsive Nanotheranostics with Dual‐Channel Fluorescent Turn‐On for Early Diagnosis and Targeted Therapy of Alzheimer's Disease
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68. Mechanisms of ozone-induced neurotoxicity in the development and progression of dementia: a brief review
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69. Decreased Bilateral FDG-PET Uptake and Inter-Hemispheric Connectivity in Multi-Domain Amnestic Mild Cognitive Impairment Patients: A Preliminary Study
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70. Aβ and the dementia syndrome: Simple versus complex perspectives
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71. Lavandula stoechas L alleviates dementia by preventing oxidative damage of cholinergic neurons in mice brain
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72. Edaravone prevents memory impairment in an animal model of post-traumatic distress
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73. Exploration of multi‐target effects of 3‐benzoyl‐5‐hydroxychromen‐2‐one in Alzheimer’s disease cell and mouse models
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74. N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible�involvement of CB1 receptor regulation
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75. Pontine Arteriolosclerosis and Locus Coeruleus Oxidative Stress Differentiate Resilience from Mild Cognitive Impairment in a Clinical Pathologic Cohort
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76. Synthesis and activities of acetylcholinesterase inhibitors
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77. Elevated activity of superoxide dismutase in male late-life schizophrenia and its correlation with clinical symptoms and cognitive deficits
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78. From Small Peptides to Large Proteins against Alzheimer’sDisease
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79. Cross-sectional Associations of Fatigue with Cerebral β-Amyloid in Older Adults at Risk of Dementia
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80. Immuno-metabolic changes in herpes virus infection
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81. Engineering exosomes for Alzheimer's disease: Multi‐target therapeutic strategies from pathogenesis to clinical translation
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82. Effects of curcumin and γ‑oryzanol solid dispersion on the brain of middle‑aged rats
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83. Energy Metabolic Disorder of Astrocytes May Be an Inducer of Migraine Attack
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84. The Association of Serum Uric Acid Level, Gout, and Alzheimer’s Disease: A Bidirectional Mendelian Randomization Study
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85. Ginsenoside compound K reduces neuronal damage and improves neuronal synaptic dysfunction by targeting Aβ
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86. Leonurine Alleviates Cognitive Dysfunction and Reduces Oxidative Stress by Activating Nrf-2 Pathway in Alzheimer’s Disease Mouse Model
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87. Signal Pathways and Intestinal Flora through Trimethylamine N-oxide in Alzheimer's Disease
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88. A leaky gut contributes to postural dysfunction in patients with Alzheimer's disease
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89. A comprehensive review on therapeutic potentials of photobiomodulation for neurodegenerative disorders
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90. Targeting misfolding and aggregation of the amyloid-β peptide and mutant p53 protein using multifunctional molecules
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91. Post‐GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3
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92. Lysosomal cholesterol accumulation in aged astrocytes impairs cholesterol delivery to neurons and can be rescued by cannabinoids
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93. Design of Multi-Target drugs of HDACs and other Anti-Alzheimer related Targets: Current strategies and future prospects in Alzheimer’s diseases therapy
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94. Discovery of gallic acid-based mitochondriotropic antioxidant attenuates LPS-induced neuroinflammation
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95. Innovative strategies for overcoming blood-brain barrier challenges in Alzheimer’s disease: A focus on green-synthesized metallic nanoparticles
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96. FTO inhibition mitigates high-fat diet-induced metabolic disturbances and cognitive decline in SAMP8 mice
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97. Regulation and mechanism of Bletilla striata polysaccharide on delaying aging in Drosophila melanogaster
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98. New histone deacetylase inhibitors and anticancer agents from Curcuma longa
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99. Amyloid-beta peptide neurotoxicity in human neuronal cells is associated with modulation of insulin-like growth factor transport, lysosomal machinery and extracellular matrix receptor interactions
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100. S-Adenosylmethionine Alleviates Amyloid-β-Induced Neural Injury by Enhancing Trans-Sulfuration Pathway Activity in Astrocytes
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