Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

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Items 101–200 of 1,001

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4. Cholesterol as a key player in amyloid β-mediated toxicity in Alzheimer’s disease
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5. Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease
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7. TrkB agonist N-acetyl serotonin promotes functional recovery after traumatic brain injury by suppressing ferroptosis via the PI3K/Akt/Nrf2/Ferritin H pathway
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10. Neuroprotective effects of verbascoside against Alzheimer’s disease via the relief of endoplasmic reticulum stress in Aβ-exposed U251 cells and APP/PS1 mice
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14. Respiratory Disease and Lower Pulmonary Function as Risk Factors for Dementia
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15. DJ-1 in neurodegenerative diseases: Pathogenesis and clinical application
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18. The Potential Role of Cytokines and Growth Factors in the Pathogenesis of Alzheimer’s Disease
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19. Suppression of 6-Hydroxydopamine-Induced Oxidative Stress by Hyperoside Via Activation of Nrf2/HO-1 Signaling in Dopaminergic Neurons
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20. Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer’s disease mouse model
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21. Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review
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22. Understanding Epigenetics in the Neurodegeneration of Alzheimer’s Disease: SAMP8 Mouse Model
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23. The Roles of Nitric Oxide Synthase/Nitric Oxide Pathway in the Pathology of Vascular Dementia and Related Therapeutic Approaches
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24. The neuroprotective effects of intermittent fasting on brain aging and neurodegenerative diseases via regulating mitochondrial function
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25. Could Alzheimer’s Disease Originate in the Periphery and If So How So?
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26. Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer’s disease
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27. Uric acid participating in female reproductive disorders: a review
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28. Huanglian Jiedu decoction remodels the periphery microenvironment to inhibit Alzheimer’s disease progression based on the “brain-gut” axis through multiple integrated omics
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29. Oxidative Damage and Antioxidant Response in Frontal Cortex of Demented and Nondemented Individuals with Alzheimer’s Neuropathology
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30. Tetrahydroxy stilbene glycoside ameliorates Alzheimer’s disease in APP/PS1 mice via glutathione peroxidase related ferroptosis
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31. Natural Therapeutics in Aid of Treating Alzheimer’s Disease: A Green Gateway Toward Ending Quest for Treating Neurological Disorders
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32. The medium-chain fatty acid decanoic acid reduces oxidative stress levels in neuroblastoma cells
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33. Lactobacillus plantarum C29‐Fermented Soybean (DW2009) Alleviates Memory Impairment in 5XFAD Transgenic Mice by Regulating Microglia Activation and Gut Microbiota Composition
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34. Noxious Iron–Calcium Connections in Neurodegeneration
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35. Polyoxometalate nanomaterials for enhanced reactive oxygen species theranostics
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36. Resveratrol: A potential therapeutic natural polyphenol for neurodegenerative diseases associated with mitochondrial dysfunction
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37. Interaction of oxidative stress and BDNF on executive dysfunction in patients with chronic schizophrenia
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38. Mechanisms of action of amyloid-beta and its precursor protein in neuronal cell death
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39. Anthocyanin as a therapeutic in Alzheimer’s disease: A systematic review of preclinical evidences
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40. Inhibition of Histone Deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer's disease: A review (2010–2020)
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41. Protective effect of daidzein against streptozotocin‐induced Alzheimer's disease via improving cognitive dysfunction and oxidative stress in rat model
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42. The role of glycogen synthase kinase 3 beta in neurodegenerative diseases
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43. A New Vision for Therapeutic Hypothermia in the Era of Targeted Temperature Management: A Speculative Synthesis
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44. Histone deacetylases as targets for the treatment of neurodegenerative disorders: Challenges and future opportunities
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45. Bioactive Food Abates Metabolic and Synaptic Alterations by Modulation of Gut Microbiota in a Mouse Model of Alzheimer’s Disease
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46. When Good Kinases Go Rogue: GSK3, p38 MAPK and CDKs as Therapeutic Targets for Alzheimer’s and Huntington’s Disease
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47. The Role of the Transcription Factor Nrf2 in Alzheimer’s Disease: Therapeutic Opportunities
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48. Functions of Astrocytes under Normal Conditions and after a Brain Disease
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49. A Triterpenoid Lupeol as an Antioxidant and Anti-Neuroinflammatory Agent: Impacts on Oxidative Stress in Alzheimer’s Disease
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50. Crosstalk between Nrf2 signaling and mitochondrial function in Parkinson's disease
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51. Direct inhibition of Keap1-Nrf2 Protein-Protein interaction as a potential therapeutic strategy for Alzheimer's disease
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52. Isorhamnetin enhanced cortico-hippocampal learning and memory capability in mice with scopolamine-induced amnesia: Role of antioxidant defense, cholinergic and BDNF signaling
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53. Dietary Supplementation of the Antioxidant Curcumin Halts Systemic LPS-Induced Neuroinflammation-Associated Neurodegeneration and Memory/Synaptic Impairment via the JNK/NF-κB/Akt Signaling Pathway in Adult Rats
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54. Smoking and Neuropsychiatric Disease—Associations and Underlying Mechanisms
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55. Multifaceted neuroprotective effects of (-)-epigallocatechin-3-gallate (EGCG) in Alzheimer’s disease: an overview of pre-clinical studies focused on β-amyloid peptide
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56. Diet’s Role in Modifying Risk of Alzheimer’s Disease: History and Present Understanding
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57. Quercetin Attenuates Oxidative Stress and Apoptosis in Brain Tissue of APP/PS1 Double Transgenic AD Mice by Regulating Keap1/Nrf2/HO‐1 Pathway to Improve Cognitive Impairment
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58. Application of CRISPR/Cas9 in Alzheimer’s Disease
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59. The use of fibroblasts as a valuable strategy for studying mitochondrial impairment in neurological disorders
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60. Vitamin D in Neurological Diseases
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61. The Vital Role of Melatonin and Its Metabolites in the Neuroprotection and Retardation of Brain Aging
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62. Therapeutic Applications and Mechanisms of Superoxide Dismutase (SOD) in Different Pathogenesis
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63. Mechanistic insight into female predominance in Alzheimer’s disease based on aberrant protein S-nitrosylation of C3
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64. Pharmacological Mechanisms Underlying the Neuroprotective Effects of Alpinia oxyphylla Miq. on Alzheimer’s Disease
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67. Comparison of malondialdehyde levels and superoxide dismutase activity in resveratrol and resveratrol/donepezil combination treatment groups in Alzheimer’s disease induced rat model
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69. Photobiomodulation for the aging brain
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70. Dietary Polyphenols as Therapeutic Intervention for Alzheimer’s Disease: A Mechanistic Insight
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71. Advances in polysaccharides of natural source of the anti-Alzheimer's disease effect and mechanism
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72. Acetyl-11-keto-β-boswellic acid ameliorates cognitive deficits and reduces amyloid-β levels in APPswe/PS1dE9 mice through antioxidant and anti-inflammatory pathways
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73. A Growing Link between Circadian Rhythms, Type 2 Diabetes Mellitus and Alzheimer’s Disease
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74. Kaempferol as a therapeutic agent in Alzheimer’s disease: Evidence from preclinical studies
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75. Protective Effects of Sesamol on Systemic Inflammation and Cognitive Impairment in Aging Mice
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76. Modifiable, Non-Modifiable, and Clinical Factors Associated with Progression of Alzheimer’s Disease
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77. Real-Time Detection and Visualization of Amyloid-β Aggregates Induced by Hydrogen Peroxide in Cell and Mouse Models of Alzheimer’s Disease
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79. Gut Microbiota Composition and Epigenetic Molecular Changes Connected to the Pathogenesis of Alzheimer’s Disease
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80. An Integrated Approach to Skeletal Muscle Health in Aging
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82. Neuroprotective and restorative properties of the GLP-1/GIP dual agonist DA-JC1 compared with a GLP-1 single agonist in Alzheimer's disease
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83. Ginkgolide B protects against cognitive impairment in senescence-accelerated P8 mice by mitigating oxidative stress, inflammation and ferroptosis
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85. Treadmill Exercise Attenuates Aβ-Induced Mitochondrial Dysfunction and Enhances Mitophagy Activity in APP/PS1 Transgenic Mice
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88. Aluminum chloride-induced amyloid β accumulation and endoplasmic reticulum stress in rat brain are averted by melatonin
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89. In Vivo Imaging with Genetically Encoded Redox Biosensors
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90. Positive Aspects of Oxidative Stress at Different Levels of the Human Body: A Review
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91. Therapeutic potential of natural molecules against Alzheimer's disease via SIRT1 modulation
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92. Amyloid-β: A double agent in Alzheimer's disease?
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93. Recent Expansions on Cellular Models to Uncover the Scientific Barriers Towards Drug Development for Alzheimer’s Disease
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94. Functional Foods: An Approach to Modulate Molecular Mechanisms of Alzheimer’s Disease
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95. Antioxidative and Anti-inflammatory Effects of Kojic Acid in Aβ-Induced Mouse Model of Alzheimer’s Disease
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96. Synthesis and biological evaluation of 1,2,4-triazole derivatives as potential neuroprotectant against ischemic brain injury
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97. Mitochondrion: a sensitive target for Pb exposure
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98. Roles of NAD(P)H:quinone Oxidoreductase 1 in Diverse Diseases
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99. Zinc in Cognitive Impairment and Aging
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100. EPA-enriched ethanolamine plasmalogen and EPA-enriched phosphatidylethanolamine enhance BDNF/TrkB/CREB signaling and inhibit neuronal apoptosis in vitro and in vivo
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