The DOI matches its Crossref record; 61 of the 62 references it cites were found in a registry or an index.
Recent Advances in Biosensor Technology for Potential Applications – An Overview
Open accessAbstract
Imperative utilization of biosensors has acquired paramount importance in the field of drug discovery, biomedicine, food safety standards, defense, security, and environmental monitoring. This has led to the invention of precise and powerful analytical tools using biological sensing element as biosensor. Glucometers utilizing the strategy of electrochemical detection of oxygen or hydrogen peroxide using immobilized glucose oxidase electrode seeded the discovery of biosensors. Recent advances in biological techniques and instrumentation involving fluorescence tag to nanomaterials have increased the sensitive limit of biosensors. Use of aptamers or nucleotides, affibodies, peptide arrays, and molecule imprinted polymers provide tools to develop innovative biosensors over classical methods. Integrated approaches provided a better perspective for developing specific and sensitive biosensors with high regenerative potentials. Various biosensors ranging from nanomaterials, polymers to microbes have wider potential applications. It is quite important to integrate multifaceted approaches to design biosensors that have the potential for diverse usage. In light of this, this review provides an overview of different types of biosensors being used ranging from electrochemical, fluorescence tagged, nanomaterials, silica or quartz, and microbes for various biomedical and environmental applications with future outlook of biosensor technology.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Wearable and mobile sensor technologies can be useful tools in precision nutrition research and practice”
From Wearable Technology to Quantify the Nutritional Intake of Adults: Validation Study (2020) · cites this paper as [14]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
ELECTRODE SYSTEMS FOR CONTINUOUS MONITORING IN CARDIOVASCULAR SURGERY
Clark, L. C., & Lyons, C. (1962) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1962.tb13623.x · Cited by 3,945 · cited 1×
“As explained above, environmental or biomedical applications demand the development of simple, swift, and ultra-sensitive biosensors.”
BackgroundDu, Z., Li, H., & Gu, T. (2007) · Biotechnology Advances · doi:10.1016/j.biotechadv.2007.05.004 · Cited by 1,707 · cited 3×
“In future, these microbial biosensors (Du et al., 2007; Sun et al., 2015) will have wider applications in monitoring environmental metal pollution and sustainable energy production.”
BackgroundNormalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers
Jain, R. K. (2013) · Journal of Clinical Oncology · doi:10.1200/jco.2012.46.3653 · Cited by 1,248 · cited 1×
“Quantum dots technology can be applied to understand the tumor microenvironment for therapeutics and also for the delivery of nano-medicine (Jain, 2013).”
BackgroundNon-invasive wearable electrochemical sensors: a review
Bandodkar, A. J., & Wang, J. (2014) · Trends in Biotechnology · doi:10.1016/j.tibtech.2014.04.005 · Cited by 1,247 · cited 2×
“Some of the advancement are seen in electrochemical sensors in combination with nanomaterials results in new types of biosensors (Kwon and Bard, 2012; Bandodkar and Wang, 2014).”
BackgroundComparative advantages of mechanical biosensors
Arlett, J., Myers, E. B., & Roukes, M. L. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.44 · Cited by 999 · cited 2×
“The ability to fabricate such structures using semiconductor processing procedures bridged biophysics and bioengineering principles toward the progress of practical micro- and nano-electromechanical biosensors that can be produced in large quantities (Arlett et al., 2011).”
BackgroundNanotechnology applications in cancer
Nie, S., Xing, Y., Kim, G. J., & Simons, J. W. (2007) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.9.060906.152025 · Cited by 952 · cited 1×
“…semiconductor quantum dots and iron oxide nanocrystals having optical as well as magnetic properties can be effectively linked with tumor targeting ligands, such as monoclonal antibodies, peptides, or small molecules to target tumor antigens with high affinity and specificity (Nie et al., 2007).”
BackgroundMicrobial biosensors: A review
Su, L., Jia, W., Hou, C., & Yu, L. (2010) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2010.09.005 · Cited by 777 · cited 1×
“Largely, usage of nanomaterials for biosensors has potential challenges, which needs to be addressed if used for biomedicine (Su et al., 2011).”
BackgroundWearable salivary uric acid mouthguard biosensor with integrated wireless electronics
Kim, J., Imani, S., de Araujo, W. R., Warchall, J., Valdés-Ramírez, G., Paixão, T. R. L. C., Mercier, P. P., & Wang, J. (2015) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2015.07.039 · Cited by 678 · cited 2×
“Some of the most-notable sensitive, real-time and portable amperometric electrochemical biosensors have been developed (Kim et al., 2015) for disease diagnosis using body fluids.”
BackgroundMethodBiosensors--Sense and Sensitivity
Turner, A. P. F. (2000) · Science · doi:10.1126/science.290.5495.1315 · Cited by 540 · cited 16×
“The first biosensor invented by Clark and Lyons (1962) to measure glucose in biological samples utilized the strategy of electrochemical detection of oxygen or hydrogen peroxide (Fracchiolla et al., 2013; Turner, 2013) using immobilized glucose oxidase electrode.”
BackgroundMethodInfluentialSilicon Nanomaterials Platform for Bioimaging, Biosensing, and Cancer Therapy
Fei, P., Su, Y., Zhong, Y., Fan, C., Lee, S., & He, Y. (2014) · Accounts of Chemical Research · doi:10.1021/ar400221g · Cited by 499 · cited 3×
“…unique features of silica or quartz or glass materials, several new biosensors were developed with high-end technology for improving bioinstrumentation to biomedicine technology yet cost-effectiveness and biosafety requires attention (Ogi, 2013; Turner, 2013; Peng et al., 2014; Shen et al., 2014).”
Background
Flagged first, then by citations
1 of the 62 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Turner, 2013, Biosensors: sense and sensibility, Chem. Soc. Rev., 42, 3184, 10.1039/c3cs35528d · DOI
Cited by
Sorted by citations
Items 501–522 of 522
Berketa, K. (2024) · Biotechnologia Acta · doi:10.15407/biotech17.02.024
Simulation and Theoretical Analysis of Plastic Optical Fiber Surface Plasmon Resonance Sensors
Varyshchuk, V. (2023) · Automation, Control, and Information Technology · doi:10.1109/acit58437.2023.10275650
“However, till now, devices based on SPR have the following disadvantages, such as limited sensitivity, performance, and relatively high cost [8, 9].”
BackgroundTuning the sensitivity of cell-based biosensors for the detection of biocides.
Morkus, P., Rassenberg, S., Montpetit, D., Filipe, C. D. M., & Latulippe, D. R. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.138740
Manimekalai, B., Arulmozhi, R., Krishnan, M., & Sivanesan, S. (2022) · Environmental Progress & Sustainable Energy · doi:10.1002/ep.13937
“ing nanostructured antibodies (AuNP-Ab) as well as the experimental substrate, in particular.(42)”
BackgroundSingh, A., Verma, N., & Kumar, K. (2022) · Current Pharmacology Reports · doi:10.1007/s40495-021-00271-8
“The biosensor technology emerged as an efficient and cost-effective asparagine detection method in contrast to standard analytical methods [6].”
MethodCharacterization of Critical Determinants of ACE2-RBD Interaction
Brown, E. E. F., Rezaei, R., Jamieson, T., Dave, J., Martin, N., Singaravelu, R., Crupi, M., Boulton, S., Tucker, S., Duong, J., et al. (2021) · bioRxiv · doi:10.1101/2021.01.29.428773
Podstawy konstrukcji biosensorów do badań biotechnologicznych
Dąbrowska, K., & Matejczyk, M. (2020) · doi:10.36921/kos.2020_2554
“Walcarius a., 2018.”
BackgroundPhysical, Physiological, and Biological Measurements
Sanei, S., Jarchi, D., & Constantinides, A. G. (2020) · Wiley eBooks · doi:10.1002/9781119390060.ch3
Recent Updates on Inkjet‐Printed Sensors
Mani, N. K., Prabhu, A., & Kumar, A. (2019) · Bioelectrochemical Interface Engineering · doi:10.1002/9781119611103.ch19
Wearable Technology to Quantify the Nutritional Intake of Adults: Validation Study (Preprint)
Dimitratos, S., German, J., & Schaefer, S. (2019) · doi:10.2196/preprints.16405
ЗАСТОСУВАННЯ КІБЕРФІЗИЧНИХ БІОСЕНСОРНИХ ТА ІМУНОСЕНСОРНИХ СИСТЕМ
Martsenyuk, V., Sverstiuk, A., Bihunyak, T. V., Pavlyshyn, A., & Mochulska, O. М. (2019) · Medical Informatics and Engineering · doi:10.11603/mie.1996-1960.2019.1.10108
Can biosensors detect contaminants in aqueous medium by impedance spectroscopy?
Bertemes, P., & Gómez-Sánchez, J. A. (2019) · International Journal of Biosensors & Bioelectronics · doi:10.15406/ijbsbe.2019.05.00152
a-Si:H p-i-n Photodiode as a Biosensor
Gradišnik, V., & Gumbarevic, D. (2018) · Photodetectors [Working Title] · doi:10.5772/intechopen.80503
“Biosensors can be label-free or label based which depends on their detection system [40].”
BackgroundVos, R., Steylaerts, T., Franquet, A., Moussa, A., Stakenborg, T., & Jans, K. (2018) · Solid State Phenomena · doi:10.4028/www.scientific.net/ssp.282.31
Biomedical diagnostics for all: Democratization and personalization
Jiang, L.-Y. (2018) · Digital Medicine · doi:10.4103/digm.digm_22_18
“We see a large wave of MDx devices Biomedical diagnostics concerns all the diseases that can be diagnosed by biosensors.[1] Pregnancy test strips are one of the most common commercialized biomedical diagnostic devices.”
BackgroundAdvanced materials in nano biosensor: A comprehensive review of design and application
Kaur, R., Arora, V., Singh, H., Chohan, J., Alrwbaye, T., & Acevedo, R. (2026) · AIP Conference Proceedings · doi:10.1063/5.0334561
Biosensors: An innovative approach in tissue engineering
Bharadwaj, A., Dabhade, P., Bagde, A., Shahare, D., & Khedkar, S. S. (2024) · AIP Conference Proceedings · doi:10.1063/5.0240723
Irannejad, N., & Rezaei, B. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-823148-7.00007-6 · Cited by 2
Hydrogels for sensing applications
Pizzetti, F., & Perale, G. (2021) · Advances in chemical engineering · doi:10.1016/bs.ache.2021.03.001
Electrochemical biosensors: State of the art and future perspectives in food analysis
(2021) · Advanced Food Analysis Tools · doi:10.1016/b978-0-12-820591-4.00009-8
A mini review on the use of biosensors for indirectly assisting the diagnosis of fibromyalgia
de Faria, R. A. D., & da Silva, J. F. (2020) · International Journal of Biosensors & Bioelectronics · doi:10.15406/ijbsbe.2020.06.00185
Futuristic Methods for Determining HIV Co-receptor Use
Flynn, J. K., Gartner, M. J., Laumaea, A., & Gorry, P. R. (2019) · Springer eBooks · doi:10.1007/978-3-030-29022-1_23
Metadata
- Authors
- Vigneshvar, S., Sudhakumari, C. C., Senthilkumaran, B., & Prakash, H.
- Affiliations
- Vellore Institute of Technology University (IN)
- University of Hyderabad (IN)
- Corresponding author
- Senthilkumaran, Balasubramanian
- Prakash, Hridayesh
- Venue
- Frontiers in Bioengineering and Biotechnology
- Publisher
- Frontiers Media SA
- Published
- 2016-02-16
- Volume
- 4
- Pages
- 11-11
- ISSN
- 2296-4185 (ISSN-L)
- PMC
- PMC4754454
- OpenAlex
- W2284805588
- Cited by
- 674
- References
- 62
- Citations by year
- 2026: 43 · 2025: 82 · 2024: 101 · 2023: 77 · 2022: 93 · 2021: 74 · 2020: 73 · 2019: 50 · 2018: 42 · 2017: 30 · 2016: 9
- FWCI
- 2.16
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Bioengineering and Biotechnology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Greater South Information System
- Funders
- Department of Science and Technology, Ministry of Science and Technology
- Topics
- Physical Sciences › Chemistry › Analytical Chemistry › Electrochemical sensors and biosensors
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
- Physical Sciences › Engineering › Biomedical Engineering › Biosensors and Analytical Detection
- Keywords
- biosensors, electrochemical biosensor, fluorescent biosensor, nanomaterials, quartz crystal microbalance, aptamers, affibody, peptide arrays, molecularly imprinted polymers, drug discovery, food safety, environmental monitoring, biosensor development
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
