The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
How Neutrophils Shape Adaptive Immune Responses
Open accessAbstract
Neutrophils are classically considered as cells pivotal for the first line of defense against invading pathogens. In recent years, evidence has accumulated that they are also important in the orchestration of adaptive immunity. Neutrophils rapidly migrate in high numbers to sites of inflammation (e.g., infection, tissue damage, and cancer) and are subsequently able to migrate to draining lymph nodes (LNs). Both at the site of inflammation as well as in the LNs, neutrophils can engage with lymphocytes and antigen-presenting cells. This crosstalk occurs either directly via cell-cell contact or via mediators, such as proteases, cytokines, and radical oxygen species. In this review, we will discuss the current knowledge regarding locations and mechanisms of interaction between neutrophils and lymphocytes in the context of homeostasis and various pathological conditions. In addition, we will highlight the complexity of the microenvironment that is involved in the generation of suppressive or stimulatory neutrophil phenotypes.
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Citations
Cites
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IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis
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Hajishengallis, G., Chavakis, T., & Lambris, J. D. (2020) · Periodontology 2000 · doi:10.1111/prd.12331 · Cited by 502
Neutrophils in Homeostasis, Immunity, and Cancer
Nicolás-Ávila, J. Á., Adrover, J. M., & Hidalgo, A. (2017) · Immunity · doi:10.1016/j.immuni.2016.12.012 · Cited by 403
Neutrophils at the crossroads of innate and adaptive immunity
Rosales, C. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.4mir0220-574rr · Cited by 372
Rice, C. M., Davies, L. C., Subleski, J. J., Maio, N., Gonzalez-Cotto, M., Andrews, C., Patel, N. L., Palmieri, E. M., Weiss, J. M., Lee, J.-M., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07505-2 · Cited by 353
The regulatory roles of neutrophils in adaptive immunity
Li, Y., Wang, W., Yang, F., Xu, Y., Feng, C., & Zhao, Y. (2019) · Cell Communication and Signaling · doi:10.1186/s12964-019-0471-y · Cited by 269
Metadata
- Authors
- Leliefeld, P. H. C., Koenderman, L., & Pillay, J.
- Venue
- Frontiers in Immunology
- Publisher
- Frontiers Media SA
- Published
- 2015-09-14
- Volume
- 6
- Pages
- 471-471
- ISSN
- 1664-3224 (ISSN-L)
- OpenAlex
- W2208851958
- Cited by
- 247
- References
- 8
- FWCI
- 7.15
- Type
- journal article
- Language
- en
- Open access
- gold
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- Leliefeld, P. H. C., Koenderman, L., & Pillay, J. (2015). How Neutrophils Shape Adaptive Immune Responses. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2015.00471
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
