The DOI matches its Crossref record; 120 of the 123 references it cites were found in a registry or an index.
Endothelial to Mesenchymal Transition Represents a Key Link in the Interaction between Inflammation and Endothelial Dysfunction
Open accessAbstract
Endothelial cells that line the inner walls of blood vessels are in direct contact with blood and display remarkable heterogeneity in their response to exogenous stimuli. These endothelial cells have unique location-dependent properties determined by the corresponding vascular beds and play an important role in regulating the homeostasis of the vascular system. Evidence suggests that vascular endothelial cells exposed to various environments undergo dynamic phenotypic switching, a key biological program in the context of endothelial heterogeneity, but that might result in endothelial cell dysfunction and, in turn, cause a variety of human diseases. Emerging studies show the importance of endothelial to mesenchymal transition (EndMT) in endothelial dysfunction during inflammation. EndMT is a complex biological process in which endothelial cells lose their endothelial characteristics, acquire mesenchymal phenotypes, and express mesenchymal cell markers such as alpha smooth muscle actin and fibroblast specific protein 1. EndMT is induced by inflammatory responses, leading to pathological states, including tissue fibrosis, pulmonary arterial hypertension, and atherosclerosis, via dysfunction of the vascular system. Although the mechanisms associated with inflammation-induced EndMT have been identified, unraveling the specific role of this phenotypic switching in vascular dysfunction remains a challenge. Here, we review the current understanding on the interactions between inflammatory processes, EndMT, and endothelial dysfunction, with a focus on the mechanisms that regulate essential signaling pathways. Identification of such mechanisms will guide future research and could provide novel therapeutic targets for the treatment of vascular diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In human and animal models, sleep disturbances pre- and post-surgery have been shown to be associated with prolonged postoperative recovery time and increased pain (reviewed in Refs. 110, 229, 571), one of the cardinal signs of inflammation.”
From The Sleep-Immune Crosstalk in Health and Disease (2019) · cites this paper as [110]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Chen, X., Xiu, M., Xing, J., Yu, S., Min, D., & Guo, F. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000479439 · Cited by 5,760
Cellular and molecular mechanisms of fibrosis
Wynn, T. (2008) · The Journal of Pathology · doi:10.1002/path.2277 · Cited by 4,495
Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
Gimbrone, M. A., & García‐Cardeña, G. (2016) · Circulation Research · doi:10.1161/circresaha.115.306301 · Cited by 3,694
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
Vandanmagsar, B., Youm, Y.-H., Ravussin, A., Galgani, J. E., Stadler, K., Mynatt, R. L., Ravussin, E., Stephens, J. M., & Dixit, V. D. (2011) · Nature Medicine · doi:10.1038/nm.2279 · Cited by 2,655
A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes
Thornberry, N. A., Bull, H. G., Calaycay, J. R., Chapman, K. T., Howard, A. D., Kostura, M. J., Miller, D. K., Molineaux, S. M., Weidner, J. R., Aunins, J. G., et al. (1992) · Nature · doi:10.1038/356768a0 · Cited by 2,613
Inflammatory links between obesity and metabolic disease
Lumeng, C. N., & Saltiel, A. R. (2011) · Journal of Clinical Investigation · doi:10.1172/jci57132 · Cited by 2,319
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
Zeisberg, E. M., Tarnavski, O., Zeisberg, M., Dorfman, A. L., McMullen, J. R., Gustafsson, E., Chandraker, A. K., Yuan, X., Pu, W. T., Roberts, A. B., et al. (2007) · Nature Medicine · doi:10.1038/nm1613 · Cited by 2,251
Dinarello, C. A. (2000) · CHEST Journal · doi:10.1378/chest.118.2.503 · Cited by 2,047
Phenotypic Heterogeneity of the Endothelium
Aird, W. C. (2007) · Circulation Research · doi:10.1161/01.res.0000255691.76142.4a · Cited by 1,824
Signaling mechanisms of the epithelial-mesenchymal transition
Gonzalez, D. M., & Medici, D. (2014) · Science Signaling · doi:10.1126/scisignal.2005189 · Cited by 1,721
Flagged first, then by citations
3 of the 123 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
The Sleep-Immune Crosstalk in Health and Disease
Besedovsky, L., Lange, T., & Haack, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00010.2018 · Cited by 1,479
“(109, 244, 336, 485, 572), as well as immunodeficiency due to impaired DC, T, and B cell functions (80, 199, 422), which in turn can promote failure of tumor and pathogen defense (123, 426) (reviewed in Ref.”
BackgroundXu, S., Ilyas, I., Little, P. J., Li, H., Kamato, D., Zheng, X., Luo, S., Li, Z., Liu, P., Han, J., et al. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000096 · Cited by 1,205
Endothelial to Mesenchymal Transition: Role in Physiology and in the Pathogenesis of Human Diseases
Piera-Velázquez, S., & Jiménez, S. A. (2019) · Physiological Reviews · doi:10.1152/physrev.00021.2018 · Cited by 688
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics
Depuydt, M. A. C., Prange, K. H. M., Slenders, L., Örd, T., Elbersen, D., Boltjes, A., de Jager, S. C. A., Asselbergs, F. W., de Borst, G. J., Aavik, E., et al. (2020) · Circulation Research · doi:10.1161/circresaha.120.316770 · Cited by 608
Yang, D., Wang, M., Zhang, C., & Wang, Y. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1359255 · Cited by 356
Resveratrol and endothelial function: A literature review
Parsamanesh, N., Asghari, A., Sardari, S., Tasbandi, A., Jamialahmadi, T., Xu, S., & Sahebkar, A. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105725 · Cited by 211
Endothelial-to-Mesenchymal Transition in Cancer
Clere, N., Renault, S., & Corre, I. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00747 · Cited by 199
Borovac, J. A., D'Amario, D., Bozic, J., & Glavas, D. (2020) · World Journal of Cardiology · doi:10.4330/wjc.v12.i8.373 · Cited by 195
Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension
Gorelova, A., Berman, M., & Ghouleh, I. A. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8169 · Cited by 185
The Key Role of Phosphate on Vascular Calcification
Cozzolino, M. G., Ciceri, P., Galassi, A., Mangano, M., Carugo, S., Capelli, I., & Cianciolo, G. (2019) · Toxins · doi:10.3390/toxins11040213 · Cited by 150
Ma, W., Wang, Y., Zhang, R., Yang, F., Zhang, D., Huang, M., Zhang, L., Dorsey, J. F., Binder, Z. A., O’Rourke, D. M., et al. (2020) · Nature Cancer · doi:10.1038/s43018-020-00147-8 · Cited by 143
Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction
D’Amario, D., Migliaro, S., Borovac, J. A., Restivo, A., Vergallo, R., Galli, M., Leone, A. M., Montone, R. A., Niccoli, G., Aspromonte, N., et al. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01347 · Cited by 138
SARS-CoV-2 Mediated Endothelial Dysfunction: The Potential Role of Chronic Oxidative Stress
Chang, R. P., Mamun, A., Dominic, A., & Le, N. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2020.605908 · Cited by 136
Metformin in cardiovascular diabetology: a focused review of its impact on endothelial function
Ding, Y., Zhou, Y., Ling, P., Feng, X., Luo, S., Zheng, X., Little, P. J., Xu, S., & Weng, J. (2021) · Theranostics · doi:10.7150/thno.64706 · Cited by 121
Thuan, D. T. B., Zayed, H., Eid, A. H., Abou-Saleh, H., Nasrallah, G. K., Mangoni, A. A., & Pintus, G. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01985 · Cited by 115
Dagher, O., Mury, P., Thorin‐Trescases, N., Noly, P., Thorin, É., & Carrier, M. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.658400 · Cited by 119
Endothelial to mesenchymal transition: at the axis of cardiovascular health and disease
Hall, I. F., Kishta, F., Xu, Y., Baker, A. H., & Kovacic, J. C. (2024) · Cardiovascular Research · doi:10.1093/cvr/cvae021 · Cited by 111
Platel, V., Faure, S., Corre, I., & Clere, N. (2019) · Journal of Oncology · doi:10.1155/2019/8361945 · Cited by 101
Srivastava, S. P., Hedayat, A. F., Kanasaki, K., & Goodwin, J. E. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00904 · Cited by 98
Liu, X., Chen, W., Li, W., Li, Y., Priest, J. R., Zhou, B., Wang, J., & Zhou, Z. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.06.092 · Cited by 87
Gaikwad, A. V., Eapen, M. S., McAlinden, K. D., Chia, C., Larby, J., Myers, S., Dey, S., Haug, G., Markos, J., Glanville, A. R., et al. (2020) · Expert Review of Respiratory Medicine · doi:10.1080/17476348.2020.1795832 · Cited by 87
Endothelial Cell Phenotype, a Major Determinant of Venous Thrombo-Inflammation
Pilard, M., Ollivier, E. L., Gourdou‐Latyszenok, V., Couturaud, F., & Lemarié, C. A. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.864735 · Cited by 88
Gan, S., Macalinao, D. G., Shahoei, S. H., Tian, L. H., Jin, X., Basnet, H., Bibby, C., Muller, J., Atri, P., Seffar, E., et al. (2024) · Cancer Cell · doi:10.1016/j.ccell.2024.08.015 · Cited by 96
LncRNA MALAT1 modulates ox-LDL induced EndMT through the Wnt/β-catenin signaling pathway
Li, H., Zhao, Q., Chang, L., Wei, C., Bei, H., Yin, Y., Chen, M., Wang, H., Liang, J., & Wu, Y. (2019) · Lipids in Health and Disease · doi:10.1186/s12944-019-1006-7 · Cited by 83
Metabolic Signatures of Distinct Endothelial Phenotypes
Dumas, S. J., García‐Caballero, M., & Carmeliet, P. (2020) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2020.05.009 · Cited by 82
Dikalov, S., & Dikalova, A. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2018.7632 · Cited by 79
Nair, A. L., Groenendijk, L., Overdevest, R., Fowke, T. M., Annida, R., Mocellin, O., de Vries, H. E., & Wevers, N. R. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1250123 · Cited by 80
Lin, P. P. (2020) · Cells · doi:10.3390/cells9061539 · Cited by 78
Intracellular endothelial cell metabolism in vascular function and dysfunction
Citrin, K. M., Chaube, B., Fernandez-Hernando, C. F., & Suárez, Y. (2024) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2024.11.004 · Cited by 81
Vascular calcification: New insights into endothelial cells
Yuan, C., Ni, L., Zhang, C., Hu, X., & Wu, X. (2020) · Microvascular Research · doi:10.1016/j.mvr.2020.104105 · Cited by 74
Inflammation and hypertension: Underlying mechanisms and emerging understandings
Aboukhater, D., Morad, B., Nasrallah, N., Nasser, S. A., Sahebkar, A., Kobeissy, F. H., Boudaka, A., & Eid, A. H. (2023) · Journal of Cellular Physiology · doi:10.1002/jcp.31019 · Cited by 78
Giordo, R., Nasrallah, G. K., Posadino, A. M., Galimi, F., Capobianco, G., Eid, A. H., & Pintus, G. (2021) · Antioxidants · doi:10.3390/antiox10020224 · Cited by 72
Ji, L., Su, S., Xin, M.-Y., Zhang, Z., Nan, X., Li, Z., & Lu, D. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154329 · Cited by 73
Cancer Biology and Prevention in Diabetes
Srivastava, S. P., & Goodwin, J. E. (2020) · Cells · doi:10.3390/cells9061380 · Cited by 77
MicroRNA targets and biomarker validation for diabetes-associated cardiac fibrosis
Jin, Z.-Q. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105941 · Cited by 69
The Gut–Vascular Barrier as a New Protagonist in Intestinal and Extraintestinal Diseases
Tommaso, N. D., Santopaolo, F., Gasbarrini, A., & Ponziani, F. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021470 · Cited by 74
Ayuso, J. M., Gong, M. M., Skala, M. C., Harari, P. M., & Beebe, D. J. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.201900925 · Cited by 73
TGF-β in Cancer: Metabolic Driver of the Tolerogenic Crosstalk in the Tumor Microenvironment
Angioni, R., Sánchez‐Rodríguez, R., Viola, A., & Molon, B. (2021) · Cancers · doi:10.3390/cancers13030401 · Cited by 73
Endothelial to Mesenchymal Transition: An Insight in Atherosclerosis
Huang, Q., Gan, Y., Yu, Z., Wu, H., & Zhong, Z. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.734550 · Cited by 68
Merčnik, M. H., Schliefsteiner, C., Sánchez‐Duffhues, G., & Wadsack, C. (2024) · Human Reproduction Update · doi:10.1093/humupd/dmae007 · Cited by 77
Tian, R., Li, R., Liu, Y., Liu, J., Pan, T., Zhang, R., Liu, B., Chen, E., Tang, Y.-Q., & Qu, H. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2019.04.009 · Cited by 67
Research progress of endothelial‐mesenchymal transition in diabetic kidney disease
Chen, Y., Zou, H., Lü, H., Xiang, H., & Chen, S. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17356 · Cited by 68
Regulation of Partial and Reversible Endothelial-to-Mesenchymal Transition in Angiogenesis
Fang, J. S., Hultgren, N. W., & Hughes, C. C. W. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.702021 · Cited by 65
Porphyromonas gingivalis regulates atherosclerosis through an immune pathway
Ruan, Q., Guan, P., Qi, W., Li, J., Xi, M., Xiao, L., Zhong, S., Ma, D., & Ni, J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1103592 · Cited by 72
The Role of Fibrinolytic Regulators in Vascular Dysfunction of Systemic Sclerosis
Kanno, Y. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030619 · Cited by 62
Giordo, R., Ahmed, Y. M. A., Allam, H., Abusnana, S., Pappalardo, L., Nasrallah, G. K., Mangoni, A. A., & Pintus, G. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.683594 · Cited by 64
Pathobiology of pulmonary artery hypertension: role of long non-coding RNAs
Zahid, K. R., Raza, U., Chen, J., Raj, U. J., & Gou, D. (2020) · Cardiovascular Research · doi:10.1093/cvr/cvaa050 · Cited by 62
Vähätupa, M., Järvinen, T. A. H., & Uusitalo‐Järvinen, H. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00873 · Cited by 61
Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19
Mothes, R., Reguant, A. P., Koehler, R., Liebeskind, J., Liebheit, A., Bauherr, S., Philipsen, L., Dittmayer, C., Laue, M. M., von Manitius, R., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36333-2 · Cited by 62
The Mechanobiology of Endothelial-to-Mesenchymal Transition in Cardiovascular Disease
Islam, S., Boström, K. I., Carlo, D. D., Simmons, C. A., Tintut, Y., Yao, Y., & Hsu, J. J. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.734215 · Cited by 59
Endothelial to Mesenchymal Transition in Pulmonary Vascular Diseases
Yun, E., Kook, Y., Yoo, K. H., Kim, K. I., Lee, M., Kim, J., & Lee, A. (2020) · Biomedicines · doi:10.3390/biomedicines8120639 · Cited by 61
Self-citationThe Role of Angiogenesis and Pro-Angiogenic Exosomes in Regenerative Dentistry
Zimța, A., Baru, O., Badea, M. E., Buduru, S. D., & Berindan‐Neagoe, I. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20020406 · Cited by 57
Protective Effect of Epigallocatechin Gallate on Endothelial Disorders in Atherosclerosis
Yamagata, K. (2020) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000792 · Cited by 60
Domingo, E., Marqués, P., Francisco, V., Piqueras, L., & Sanz, M. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107058 · Cited by 63
Chen, X., Lin, J., Hu, T., Ren, Z., Li, L., Hameed, I., Zhang, X., Men, C., Guo, Y., Xu, D., et al. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27910 · Cited by 52
Endothelial to mesenchymal transition in atherosclerotic vascular remodeling
Hao, Y., Yuan, H., Ren, Z., Qu, S.-L., Liu, L.-S., Dang-HengWei, Yin, K., Fu, M., & Jiang, Z. (2018) · Clinica Chimica Acta · doi:10.1016/j.cca.2018.12.018 · Cited by 53
Zhao, P., Yao, Q., Zhang, P., The, E., Zhai, Y., Ao, L., Jarrett, M. J., Dinarello, C. A., Fullerton, D. A., & Meng, X. (2021) · Science Advances · doi:10.1126/sciadv.abg1694 · Cited by 49
Endothelial-to-Mesenchymal Transition in Calcific Aortic Valve Disease.
Ma, X., Zhao, D., Yuan, P., Li, J., Yun, Y., Cui, Y., Zhang, T., Ma, J., Sun, L., Ma, H., et al. (2020) · PubMed Central · doi:10.6515/acs.202005_36(3).20200213a · Cited by 49
Zhao, H., Guo, Y., Sun, Y., Zhang, N., & Wang, X. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.29318 · Cited by 48
Clinical Implications of Uric Acid in Heart Failure: A Comprehensive Review
Kumrić, M., Borovac, J. A., Kurir, T. T., & Božić, J. (2021) · Life · doi:10.3390/life11010053 · Cited by 49
Tang, B., Liu, Y., Zhang, J., Lü, M., & Wang, H. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114920 · Cited by 46
Guo, S., Zhou, Y., & Xie, X. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113775 · Cited by 44
Wang, J., Yu, M., Xu, J., Cheng, Y., Li, X., Wei, G., Wang, H., Kong, H., & Xie, W. (2019) · Journal of Biomedical Science · doi:10.1186/s12929-019-0496-y · Cited by 42
Sun, Z., Zhao, H., Fang, D., Davis, C. T., Shi, D., Lei, K., Rich, B. E., Winter, J. M., Guo, L., Sorensen, L. K., et al. (2022) · Neuron · doi:10.1016/j.neuron.2022.07.015 · Cited by 43
Gorica, E., Geiger, M. A., Venanzio, L. D., Atzemian, N., Kleeberger, J., Grigorian, D., Mongelli, A., Veseli, B. E., Mohammed, S. A., Ruschitzka, F. T., et al. (2025) · Cardiovascular Diabetology · doi:10.1186/s12933-025-02774-w · Cited by 50
Endothelial-to-mesenchymal transition: An underappreciated mediator of diabetic complications
Wang, E., Wang, H., & Chakrabarti, S. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1050540 · Cited by 44
Migneault, F., Dieudé, M., Turgeon, J., Beillevaire, D., Hardy, M., Brodeur, A., Thibodeau, N., Perreault, C., & Hébert, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-69548-0 · Cited by 42
Yan, Y., Li, T., Li, Z., He, M., Wang, D., Xu, Y., Yang, X., Bai, Y., Lao, Y., Zhang, Z., et al. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.690627 · Cited by 42
Yu, M., Wu, X., Wang, J., He, M., Han, H., Hu, S., Xu, J., Yang, M., Tan, Q., Wang, Y., et al. (2022) · International Journal of Medical Sciences · doi:10.7150/ijms.69289 · Cited by 40
Chen, J., Jia, J., Ma, L., Li, B., Qin, Q., Qian, J., & Ge, J. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29877 · Cited by 40
Qian, C., Dong, G., Yang, C., Zheng, W., Zhong, C., Shen, Q., Lu, Y., & Zhao, Y. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02028-y · Cited by 42
SHIP‐1, a target of miR‐155, regulates endothelial cell responses in lung fibrosis
Tang, H., Mao, J., Ye, X., Zhang, F., Kerr, W. G., Zheng, T., & Zhu, Z. (2019) · The FASEB Journal · doi:10.1096/fj.201902063r · Cited by 39
Resident vascular endothelial progenitor definition and function: the age of reckoning
Dight, J., Zhao, J., Styke, C., Khosrotehrani, K., & Patel, J. (2021) · Angiogenesis · doi:10.1007/s10456-021-09817-2 · Cited by 39
Sasaki, Y., Raza-Iqbal, S., Tanaka, T., Murakami, K., Anai, M., Osawa, T., Matsumura, Y., Sakai, J., & Kodama, T. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225682 · Cited by 40
Molecular mechanisms of endothelial remodeling under doxorubicin treatment
Podyacheva, E., Danilchuk, M., & Toropova, Y. G. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114576 · Cited by 37
Marden, G., Wan, Q., Wilks, J., Nevin, K., Feeney, M., Wisniacki, N., Trojanowski, M. A., Bujor, A. M., Stawski, L., & Trojanowska, M. (2020) · Arthritis Research & Therapy · doi:10.1186/s13075-020-02266-0 · Cited by 37
Calciprotein Particles Cause Endothelial Dysfunction under Flow
Shishkova, D. K., Markova, V. E., Sinitsky, M. Y., Цепокина, А. В., Velikanova, E. A., Bogdanov, L. A., Glushkova, T. V., & Кутихин, А. Г. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228802 · Cited by 37
Endothelial OCT4 is atheroprotective by preventing metabolic and phenotypic dysfunction
Shin, J., Tkachenko, S., Chaklader, M., Pletz, C., Singh, K., Bulut, G. B., Han, Y. M., Mitchell, K., Baylis, R. A., Kuzmin, A. A., et al. (2022) · Cardiovascular Research · doi:10.1093/cvr/cvac036 · Cited by 37
Niayesh‐Mehr, R., Kalantar, M., Bontempi, G., Montaldo, C., Ebrahimi, S., Allameh, A., Babaei, G., Seif, F., & Strippoli, R. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01925-y · Cited by 36
Ciavarella, C., Motta, I., Vasuri, F., Fittipaldi, S., Valente, S., Pollutri, D., Ricci, F., Gargiulo, M., & Pasquinelli, G. (2021) · Biomolecules · doi:10.3390/biom11020226 · Cited by 36
IL-1β in atherosclerotic vascular calcification: From bench to bedside
Shen, J., Zhao, M., Zhang, C., & Sun, X. (2021) · International Journal of Biological Sciences · doi:10.7150/ijbs.66537 · Cited by 37
Guo, Y., Wang, X., Jia, P., You, Y., Cheng, Y., Deng, H., Luo, S., & Huang, B. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118124 · Cited by 35
Jiang, L., Hao, C.-J., Li, Z., Zhang, P., Wang, S., Yang, S., Wei, F., & Zhang, J. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.11.114 · Cited by 34
Stem Cells in Keloid Lesions: A Review
Lim, K. H., Itinteang, T., Davis, P. F., & Tan, S. T. (2019) · Plastic & Reconstructive Surgery Global Open · doi:10.1097/gox.0000000000002228 · Cited by 34
Endothelial Dysfunction in the Context of Blood–Brain Barrier Modeling
Kutikhin, A. G., Shishkova, D. K., Velikanova, E. A., Sinitsky, M. Y., Sinitskaya, A. V., & Markova, V. E. (2022) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093022030139 · Cited by 36
Panorama of artery endothelial cell dysfunction in pulmonary arterial hypertension
Shen, Y.-H., Ding, D., Lian, T., Qiu, B., Yan, Y., Wang, P., Zhang, W., & Jing, Z. (2024) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2024.10.004 · Cited by 34
Lu, W., Teoh, A. K. Y., Waters, M., Haug, G., Shakeel, I., Hassan, M. I., Shahzad, A. M., Larsson‐Callerfelt, A., Piccari, L., & Sohal, S. S. (2024) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2024.108757 · Cited by 35
The Role of NLRP3 Inflammasome in Radiation-Induced Cardiovascular Injury
Huang, S., Che, J., Chu, Q., & Zhang, P. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00140 · Cited by 33
Ma, K., Li, C., Xu, J., Ren, F., Xu, X. Y., Liu, C., Niu, B., & Li, F. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111327 · Cited by 33
Srivastava, S. P., Goodwin, J. E., Tripathi, P., Kanasaki, K., & Koya, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22116027 · Cited by 33
Fibrotic Changes to Schlemm’s Canal Endothelial Cells in Glaucoma
Kelly, R. A., Perkumas, K. M., Campbell, M., Farrar, G. J., Stamer, W. D., Humphries, P., O’Callaghan, J., & O'Brien, C. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179446 · Cited by 32
Alpha-Smooth Muscle Actin-Positive Perivascular Cells in Diabetic Retina and Choroid
Kim, S., Kim, S. A., Choi, Y. A., Park, D. Y., & Lee, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21062158 · Cited by 31
Rossato, F. A., Su, Y., Mackey, A. M., & Ng, Y. (2020) · Cells · doi:10.3390/cells9092057 · Cited by 31
Current Nanomedicine for Targeted Vascular Disease Treatment: Trends and Perspectives
Choi, K.-A., Kim, J. H., Ryu, K., & Kaushik, N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012397 · Cited by 33
Self-citationMechanosensory entities and functionality of endothelial cells
Mierke, C. T. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1446452 · Cited by 36
Multifaced roles of adipokines in endothelial cell function
Yan, Y., Wang, L., Zhong, N., Wen, D., & Liu, L. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1490143 · Cited by 30
You, N., Liu, G., Yu, M., Chen, W., Fei, X., Sun, T., Han, M., Qin, Z., Wei, Z., & Wang, D. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2024.12.049 · Cited by 31
A dual role of YAP in driving TGFβ-mediated endothelial-to-mesenchymal transition
Savorani, C., Malinverno, M., Seccia, R., Maderna, C., Giannotta, M., Terreran, L., Mastrapasqua, E., Campaner, S., Dejana, E., & Giampietro, C. (2021) · Journal of Cell Science · doi:10.1242/jcs.251371 · Cited by 30
Cai, D., & Chen, S. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102524 · Cited by 30
Charoenwoodhipong, P., Zuelch, M. L., Keen, C. L., Hackman, R. M., & Holt, R. R. (2024) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2024.2398634 · Cited by 34
Metadata
- Authors
- Cho, J. G., Lee, A., Chang, W., Lee, M.-S., & Kim, J.
- Affiliations
- Sookmyung Women's University (KR)
- Pusan National University (KR)
- Corresponding author
- Kim, Jongmin
- Venue
- Frontiers in Immunology
- Publisher
- Frontiers Media SA
- Published
- 2018-02-20
- Volume
- 9
- Pages
- 294-294
- ISSN
- 1664-3224 (ISSN-L)
- PMC
- PMC5826197
- OpenAlex
- W2793749910
- Cited by
- 284
- References
- 123
- Citations by year
- 2026: 25 · 2025: 38 · 2024: 33 · 2023: 40 · 2022: 29 · 2021: 36 · 2020: 49 · 2019: 26 · 2018: 7
- FWCI
- 2.89
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Frontiers in Immunology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Research Foundation (NRF-2016R1A5A1011974)
- National Research Foundation of Korea (NRF-2016R1A5A1011974, NRF-2016R1C1B2006591, 2016R1A5A1011974)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › TGF-β signaling in diseases
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Health Sciences › Medicine › Oncology › Cancer Cells and Metastasis
- Keywords
- endothelial-to-mesenchymal transition, endothelial dysfunction, inflammation, endothelial heterogeneity, fibrosis, pulmonary arterial hypertension, atherosclerosis, vascular dysfunction, signaling pathways, therapeutic target
- MeSH terms
- Humans, Inflammation, Vascular Diseases, Endothelial Cells, Cell Transdifferentiation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
