The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Review of Antimicrobial Resistance in the Environment and Its Relevance to Environmental Regulators
Open accessAbstract
The environment is increasingly being recognized for the role it might play in the global spread of clinically relevant antibiotic resistance. Environmental regulators monitor and control many of the pathways responsible for the release of resistance-driving chemicals into the environment (e.g., antimicrobials, metals, and biocides). Hence, environmental regulators should be contributing significantly to the development of global and national antimicrobial resistance (AMR) action plans. It is argued that the lack of environment-facing mitigation actions included in existing AMR action plans is likely a function of our poor fundamental understanding of many of the key issues. Here, we aim to present the problem with AMR in the environment through the lens of an environmental regulator, using the Environment Agency (England's regulator) as an example from which parallels can be drawn globally. The issues that are pertinent to environmental regulators are drawn out to answer: What are the drivers and pathways of AMR? How do these relate to the normal work, powers and duties of environmental regulators? What are the knowledge gaps that hinder the delivery of environmental protection from AMR? We offer several thought experiments for how different mitigation strategies might proceed. We conclude that: (1) AMR Action Plans do not tackle all the potentially relevant pathways and drivers of AMR in the environment; and (2) AMR Action Plans are deficient partly because the science to inform policy is lacking and this needs to be addressed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Removal of heavy metal ions from wastewaters: A review
Fu, F., & Wang, Q. (2011) · Journal of Environmental Management · doi:10.1016/j.jenvman.2010.11.011 · Cited by 8,703
Antibiotic resistance is ancient
D’Costa, V. M., King, C. E., Kalan, L., Morar, M., Sung, W. W. L., Schwarz, C., Froese, D., Zazula, G., Calmels, F., Debruyne, R., et al. (2011) · Nature · doi:10.1038/nature10388 · Cited by 2,720
Occurrence of Antibiotics in the Aquatic Environment
Hirsch, R., Ternes, T., Haberer, K., & Kratz, K.-L. (1999) · Science of The Total Environment · doi:10.1016/s0048-9697(98)00337-4 · Cited by 2,140 · cited 1×
“Antibiotics found in manure- or sludge-amended agricultural soils will enter groundwater as a result of rainfall, irrigation, and other human activities (Hirsch et al., 1999; Hu et al., 2010; Sui et al., 2015).”
BackgroundThe shared antibiotic resistome of soil bacteria and human pathogens
Forsberg, K. J., Reyes, A., Wang, B., Selleck, E. M., Sommer, M. O. A., & Dantas, G. (2012) · Science · doi:10.1126/science.1220761 · Cited by 1,650
Pharmaceuticals as emerging contaminants and their removal from water. A review
Rivera-Utrilla, J., Sánchez-Polo, M., Ferro-García, M. Á., Prados-Joya, G., & Ocampo-Pérez, R. (2013) · Chemosphere · doi:10.1016/j.chemosphere.2013.07.059 · Cited by 1,486
SOS response promotes horizontal dissemination of antibiotic resistance genes
Beaber, J. W., Hochhut, B., & Waldor, M. K. (2004) · Nature · doi:10.1038/nature02241 · Cited by 1,186
Antibiotic resistance gene spread due to manure application on agricultural fields
Heuer, H., Schmitt, H., & Smalla, K. (2011) · Current Opinion in Microbiology · doi:10.1016/j.mib.2011.04.009 · Cited by 985
Intrinsic and acquired resistance mechanisms in enterococcus
Hollenbeck, B. L., & Rice, L. B. (2012) · Virulence · doi:10.4161/viru.21282 · Cited by 795
Sui, Q., Cao, X., Lu, S., Zhao, W., Qiu, Z., & Yu, G. (2015) · Emerging Contaminants · doi:10.1016/j.emcon.2015.07.001 · Cited by 664
Buffet-Bataillon, S., Tattevin, P., Bonnaure-Mallet, M., & Jolivet-Gougeon, A. (2012) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2012.01.011 · Cited by 601 · cited 2×
“…as alkyldimethyl-benzyl-ammonium chloride (ADBAC), stearalkonium chloride, isothiazoliumbenzalkonium chloride, cetrimonium chloride/bromide (cetrimide), cetylpyridinium chloride, alkyl amino alkyl glycines and didecyldimethylammonium chloride (DDAC)] (Russell, 2003; Buffet-Bataillon et al., 2012).”
BackgroundInfluential
Cited by
Antibiotic resistance in the environment
Larsson, D. G. J., & Flach, C.-F. (2022) · Nature Reviews Microbiology · doi:10.1038/s41579-021-00649-x · Cited by 3,164
Manyi-Loh, C., Mamphweli, S., Meyer, E., & Okoh, A. (2018) · Molecules · doi:10.3390/molecules23040795 · Cited by 1,808
Antibiotic Resistance: One Health One World Outlook
Aslam, B., Khurshid, M., Arshad, M. I., Muzammil, S., Rasool, M., Yasmeen, N., Shah, T., Chaudhry, T. H., Rasool, M. H., Shahid, A., et al. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.771510 · Cited by 609
Current status and future challenges in implementing and upscaling vertical farming systems
van Delden, S. H., SharathKumar, M., Butturini, M., Graamans, L. J. A., Heuvelink, E., Kacira, M., Kaiser, E., Klamer, R. S., Klerkx, L., Kootstra, G., et al. (2021) · Nature Food · doi:10.1038/s43016-021-00402-w · Cited by 544
Antimicrobial resistance in the environment: The Indian scenario
Taneja, N., & Sharma, M. (2019) · Indian Journal of Medical Research · doi:10.4103/ijmr.ijmr_331_18 · Cited by 317
Metadata
- Authors
- Singer, A. C., Shaw, H., Rhodes, V., & Hart, A.
- Venue
- Frontiers in Microbiology
- Publisher
- Frontiers Media SA
- Published
- 2016-11-01
- Volume
- 7
- Pages
- 1728-1728
- ISSN
- 1664-302X (ISSN-L)
- OpenAlex
- W2547337573
- Cited by
- 844
- References
- 12
- FWCI
- 27.05
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Review of Antimicrobial Resistance in the Environment and Its Relevance to Environmental Regulators. https://app.cochat.ai/papers/10.3389/fmicb.2016.01728
- The paper
- Singer, A. C., Shaw, H., Rhodes, V., & Hart, A. (2016). Review of Antimicrobial Resistance in the Environment and Its Relevance to Environmental Regulators. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2016.01728
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
